1. Zhongping Chen

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    1. Mentioned In 227 Articles

    2. Optical Coherence Tomography of the Cochlea in the Porcine Model.

      Abstract: Objectives/Hypothesis: To demonstrate the feasibility of optical coherence tomography in microstructural imaging of the porcine cochlea. Study Design: Ex vivo, porcine model. Methods: Optical coherence tomographic images of the porcine cochlea were obtained by thinning the bone from the basal turn of the cochlea leaving the endosteum intact. The images were compared with the corresponding histological sections. Results: In the areas of thinned bone, images were obtained of ...
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    3. High speed spectral domain functional optical coherence tomography and optical doppler tomography for in vivo blood flow dynamics and tissue structure

      A system for tomographic imaging includes a source of at least partially coherent radiation, a frequency-swept laser source and an interferometer. The radiation in the interferometer is phase modulated at a modulation frequency for elimination of DC and autocorrelation noises as well as the mirror image. The interference fringes of the radiation backscattered from the sample into the interferometer are detected to obtain a spectral signal. The spectral signal of ...
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    4. Optical coherence tomography of the larynx in the awake patient

      Objective To demonstrate the feasibility of performing optical coherence tomography of the human larynx on the awake patient with a novel flexible fiberoptic delivery system. Study Design Prospective clinical trial. Subjects and Methods Imaging was performed in 17 awake patients. A flexible optical coherence tomography probe was inserted through the nose and placed in near or gentle contact with laryngeal tissues under direct endoscopic visualization. Results Images were successfully obtained ...
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    5. Imaging treated brain aneurysms in vivo using optical coherence tomography

      Jianping Su, Marlon S. Mathews, Chiedozie I. Nwagwu et al. Angiography is currently used to assess post-treatment human brain aneurysm healing, which can reveal vessel shape only. Optical coherence tomography (OCT) can reveal the vessel wall structure with high resolution, which has the advantage to assess vessel healing progress. An OCT endovascular cathet ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684732 (2008)] published Mon Feb 18, 2008.
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    6. High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs

      High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs
      We report on the development of a high-speed, wide bandwidth Fourier domain mode-locked (FDML) wavelength swept laser of around 1300 nm using two gain media for high-resolution and high-speed Fourier domain optical coherence tomography. The wavelength swept laser is capable of FWHM scanning range ... [Opt. Express 16, 2547-2554 (2008)]
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    7. Imaging of the Pediatric Airway Using Optical Coherence Tomography

      Objectives: Optical coherence tomography (OCT) is an imaging modality that uses a broadband light source to produce high‐resolution cross‐sectional images in living tissue (820 m). A prospective study of normal, benign, and pathologic tissues in the pediatric airway was conducted to assess the utility of OCT technology in characterizing the microanatomy of the pediatric upper aerodigestive tract in vivo. Study Design: Prospective clinical trial. Materials and Methods: Fifteen ...
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    8. 196-210 of 227 « 1 2 ... 11 12 13 14 15 »
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  2. About Zhongping Chen

    Zhongping Chen

    Zhongping Chen is a Professor of Biomedical Engineering and Director of the F-OCT Laboratory at the University of California, Irvine. He is a Co-founder and Chairman of OCT Medical Imaging Inc. Dr. Chen received his B.S. degree in Applied Physics from Shanghai Jiao Tong University in 1982, his M.S. degree in Electrical Engineering in 1987, and his Ph.D. degree in Applied Physics from Cornell University in 1993. Dr. Chen’s research interests encompass the areas of biomedical photonics, microfabrication, biomaterials and biosensors. His research group has pioneered the development of functional optical coherence tomography, which simultaneously provides high resolution 3-D images of tissue structure, blood flow, and birefringence. These functional extensions of OCT offer contrast enhancements and provide mapping of many clinically important parameters. In addition, his group has developed a number of endoscopic and intravascular rotational and linear 2-D probes for OCT and MPM imaging and translated these technologies to clinical applications through collaboration with clinicians. He has led numerous major research projects funded by NIH, NSF, DOD, and DARPA, including several interdisciplinary research projects such as the NIH Biomedical Research Partnership (BRP) grant and NSF Biophotonics Partnership Initiative grant. Dr. Chen has published more than 200 peer-reviewed papers and review articles and holds a number of patents in the fields of biomaterials, biosensors, and biomedical imaging. Dr. Chen is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), a Fellow of SPIE, and a Fellow of the Optical Society of America.