1. Zhongping Chen

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    181-195 of 227 « 1 2 ... 10 11 12 13 14 15 »
    1. Mentioned In 227 Articles

    2. Gradient-index lens rod based probe for office-based optical coherence tomography of the human larynx

      Optical coherence tomography (OCT) is an evolving noninvasive imaging modality that has been used to image the human larynx during surgical endoscopy. The design of a long gradient-index lens-based probe capable of capturing images of the human larynx by use of spectral domain OCT during a typical o ... [J. Biomed. Opt. 14, 014017 (2009)] published Wed Feb 11, 2009.
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    3. Effect of Erythrocyte Aggregation on Hematocrit Measurement Using Spectral-Domain Optical Coherence Tomography

      Optical coherence tomography (OCT) has the potential to be a noninvasive method for hematocrit (HCT) measurement. This study shows the effect of erythrocyte aggregation at the level seen in healthy humans and pathological states on HCT measurement based on monitoring the slope changes in OCT depth reflectivity profile using spectral-domain optical coherence tomography (SDOCT). Our measurement indicates that the HCT estimated by SDOCT depends on the erythrocyte aggregation state and ...
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    4. Imaging the Human Tympanic Membrane Using Optical Coherence Tomography In Vivo.

      Objective: Optical coherence tomography (OCT) is a diagnostic imaging modality that combines low coherence light with interferometry to produce high-resolution cross-sectional images of living tissues. Using this technology, we have imaged in vivo the human tympanic membrane (TM) in the office clinic setting and characterized TM microstructure in normal and pathologic conditions. Study Design: Prospective clinical trial. Materials and Methods: The normal and diseased TMs in 10 adult subjects were ...
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    5. An optical coherence tomography (OCT)-based air jet indentation system for measuring the mechanical properties of soft tissues

      Abstract. A novel noncontact indentation system with the combination of an air jet and optical coherence tomography (OCT) was presented in this paper for the quantitative measurement of the mechanical properties of soft tissues. The key idea of this method is to use a pressure-controlled air jet as an indenter to compress the soft tissue in a noncontact way and utilize the OCT signals to extract the deformation induced. This ...
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    6. Topographical variations in the polarization sensitivity of articular cartilage as determined by polarization-sensitive optical coherence tomography and polarized light microscopy

      ... Irvine, California 92612 Patrick Hoover Oakland University, Department of Physics, Rochester, Michigan 48309 Zhongping Chen University of California, Irvine, College of Medicine, Beckman Laser Institute and Medical Cl...
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    7. Optical Coherence Tomography–Enhanced Microlaryngoscopy: Preliminary Report of a Noncontact Optical Coherence Tomography System Integrated With a Surgical Microscope

      ... MS; Shuguang Guo, PhD; Jorge A. Perez, BS; Jianping Su, MS; James M. Ridgway, MD; William B. Armstrong, MD; Zhongping Chen, PhD; Brian J. F. Wong, MD, PhD Objectives: Optical coherence tomography (OCT) is a new imaging...
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    8. Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor

      ... ABSTRACT REFERENCES (13) Jianping Su,^1 Jun Zhang,^2 Lingfeng Yu,^2 Henri G Colt,^3 Matthew Brenner,^2,3 and Zhongping Chen^1,2 ^1University of California, Irvine, Department of Biomedical Engineering, Irvine, Californi...
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    9. High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs.

      Related Articles High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs. Opt Express. 2008 Feb 18;16(4):2547-54 Authors: Jeon MY, Zhang J, Wang Q, Chen Z We report on the development of a high-speed, wide bandwidth Fourier domain mode-locked (FDML) wavelength swept laser of around 1300 nm using two gain media for high-resolution and high-speed Fourier domain optical coherence tomography. The wavelength swept laser ...
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    10. 181-195 of 227 « 1 2 ... 10 11 12 13 14 15 »
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  2. About Zhongping Chen

    Zhongping Chen

    Zhongping Chen is a Professor of Biomedical Engineering and Director of the F-OCT Laboratory at the University of California, Irvine. He is a Co-founder and Chairman of OCT Medical Imaging Inc. Dr. Chen received his B.S. degree in Applied Physics from Shanghai Jiao Tong University in 1982, his M.S. degree in Electrical Engineering in 1987, and his Ph.D. degree in Applied Physics from Cornell University in 1993. Dr. Chen’s research interests encompass the areas of biomedical photonics, microfabrication, biomaterials and biosensors. His research group has pioneered the development of functional optical coherence tomography, which simultaneously provides high resolution 3-D images of tissue structure, blood flow, and birefringence. These functional extensions of OCT offer contrast enhancements and provide mapping of many clinically important parameters. In addition, his group has developed a number of endoscopic and intravascular rotational and linear 2-D probes for OCT and MPM imaging and translated these technologies to clinical applications through collaboration with clinicians. He has led numerous major research projects funded by NIH, NSF, DOD, and DARPA, including several interdisciplinary research projects such as the NIH Biomedical Research Partnership (BRP) grant and NSF Biophotonics Partnership Initiative grant. Dr. Chen has published more than 200 peer-reviewed papers and review articles and holds a number of patents in the fields of biomaterials, biosensors, and biomedical imaging. Dr. Chen is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), a Fellow of SPIE, and a Fellow of the Optical Society of America.