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2. The relation between optical coherence tomography-detected layered pattern and acute side branch occlusion after provisional stenting of coronary bifurcation lesions
  
  Explore ScienceDirect Jan 1 2019 Cardiology
  
  Background/Purpose. Layered pattern (presumed to be healed plaque after a thrombotic event) can be observed by optical coherence tomography (OCT). We sought to assess the ability of OCT-detected plaque composition to predict acute side branch (SB) occlusion after provisional bifurcation stenting. Methods This is a retrospective observational study using pre-intervention OCT in the main vessel to predict Thrombolysis in Myocardial Infarction (TIMI) flow grade 1 in a SB (diameter ...
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  Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz
3. Viscosity monitoring during hemodiluted blood coagulation using optical coherence elastography
  
  Explore IEEE Xplore Jun 5 2018
  
  Rapid and accurate clot diagnostic systems are needed for the assessment of hemodiluted blood coagulation. We develop a real-time optical coherence elastography (OCE) system, which measures the attenuation coefficient of a compressional wave induced by a piezoelectric transducer (PZT) in a drop of blood using optical coherence tomography (OCT), for the determination of viscous properties during the dynamic whole blood coagulation process. Changes in the viscous properties increase the attenuation ...
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  Mentions: UC Irvine Zhejiang University Jiang Zhu
4. Loquat Bruise Detection Using Optical Coherence Tomography Based on Microstructural Parameters
  
  Explore Home - Springer Apr 26 2018 NDE/NDT , Other Non-Medical
  
  Slight postharvest bruises of loquats remarkably affect the quality and shelf life of the fruits, but they are difficult to identify using visual inspection. Sub-surface structural changes in cells caused by mechanical injury or impact can be detected using spectroscopy-based methods from different angles. Optical coherence tomography (OCT), a non-destructive technology, can acquire cross-sectional images to analyze sub-surface structures of loquats, thus offering the potential to identify fruit bruises. This ...
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  Mentions: Zhejiang University
5. All-fiber probe for optical coherence tomography with an extended depth of focus by a high-efficient fiber-based filter
  
  Explore ScienceDirect Jan 5 2018 Probes
  
  Although methods have been proposed to maintain high transverse resolution over an increased depth range, it is not straightforward to scale down the bulk-optic solutions to minimized probes of optical coherence tomography (OCT). In this paper, we propose a high-efficient fiber-based filter in an all-fiber OCT probe to realize an extended depth of focus (DOF) while maintaining a high transverse resolution. Mode interference in the probe is exploited to modulate ...
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  Mentions: Zhihua Ding Zhejiang University Peng Li
6. Adaptive classifier allows enhanced flow contrast in OCT angiography using a histogram-based motion threshold and 3D Hessian analysis-based shape filtering
  
  Explore OSA | OSA Publishing Dec 8 2017
  
  In this Letter, we propose an adaptive digital classifier for flow contrast enhancement in optical coherence tomography angiography (OCTA). To solve the depth dependence in the initial motion-based classification, a depth-adaptive motion threshold was determined by performing a histogram analysis of an en-face image at each depth and identifying the static and dynamic voxel populations through fitting. In the follow-up shape-based classification, to adapt to the deformed vessel shapes in ...
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  Mentions: Zhejiang University Peking University Qiushi Ren
7. Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography
  
  Explore OSA | OSA Publishing Oct 18 2017
  
  In this study, we demonstrated the feasibility of using a handheld optical coherence tomography (OCT) for in vivo visualizations of the microstructural and microvascular features of various oral mucosal types. To scan arbitrary locations of the oral mucosa, a scanning probe was developed, composed of a probe body fabricated by a 3D printer, miniaturized two-axis galvanometer, relay lenses, and reflective prism. With a 3D printing technique, the probe weight and ...
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  Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University
8. Phase and amplitude correction in polygon tunable laser-based optical coherence tomography
  
  Explore SPIE Digital Library Oct 10 2017
  
  Phase instability is a serious problem in swept-source optical coherence tomography (OCT) with polygon tunable lasers; however, these devices have additional issues. We found that polygon tunable lasers also have fluctuations in output power and sweep range: the former creates artifacts that may impair the recognition of sample information, and the latter reduces the interference signal utilization during phase correction. We demonstrate a method that uses the calibration signal to ...
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  Mentions: Zhejiang University
9. Spectral-domain optical coherence tomography dynamic changes and steroid response in multiple evanescent white dot syndrome
  
  Explore 欢迎访问国际眼科杂志编辑部 Sep 2 2017 Ophthalmology
  
  Dear Editor, Multiple evanescent white dot syndrome (MEWDS) was first described in 1984 as a rare, acute, unilateral, multifocal retinochoroidal disorder, typically affecting young myopic women[1]. Previous studies with fluorescein angiography (FA) and electrophysiology suggested that MEWDS to be a disease in the retinal pigment epithelium (RPE) or outer retina[2], while recent studies with spectraldomain optical coherence tomography (SD-OCT) suggested it may be an outer retinal disease due ...
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  Mentions: Zhejiang University
10. In Vivo Calcium Detection by Comparing Optical Coherence Tomography, Intravascular Ultrasound, and Angiography
  
  Explore ScienceDirect Aug 8 2017 Cardiology
  
  Objectives The aim of this study was to evaluate optical coherence tomography (OCT) and intravascular ultrasound (IVUS) versus coronary angiography in the assessment of target lesion calcification and its effect on stent expansion. Background IVUS is more sensitive than angiography in the detection of coronary artery calcium, but the relationship among IVUS, OCT, and angiography has not been studied. Methods Overall, 440 lesions (440 patients with stable angina) underwent OCT- ...
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  Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz
11. Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe
  
  Explore Home - Springer Jul 22 2017
  
  Biomedical materials have different optical properties (e.g. absorption) for different wavelengths. Therefore, probing biomedical materials with multiple wavelengths not only can get in-depth understanding of the detected biomedical materials but also can differentiate the detected biomedical materials. To achieve this purpose, in this conference paper, we present our initial results of building up a portable multiple-wavelength biomedical sensing system. At this initial phase, we assembled this kind of system ...
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  Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University
12. Lens-free all-fiber probe with an optimized output beam for optical coherence tomography
  
  Explore OSA | OSA Publishing Jul 14 2017 Probes
  
  A high-efficiency lensless all-fiber probe for optical coherence tomography (OCT) is presented. The probe is composed of a segment of large-core multimode fiber (MMF), a segment of tapered MMF, and a length of single-mode fiber (SMF). A controllable output beam can be designed by a simple adjustment of its probe structure parameters (PSPs), instead of the selection of fibers with different optical parameters. A side-view probe with a diameter of ...
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  Mentions: Zhihua Ding Zhejiang University Yi Shen
13. Quasi-needle-like focus synthesized by optical coherence tomography
  
  Explore OSA | OSA Publishing Mar 28 2017
  
  It is known that lateral resolution and depth of focus (DOF) in an optical imaging system are coupled, and a compromise between them has to be made. In this Letter, we propose to resolve the trade-off between lateral resolution and the DOF by a synthetic effective point spread function in optical path length (OPL) domain. A quasi-needle-like focus is synthesized by optical coherence tomography. We demonstrate that the synthesized quasi-needle-like ...
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  Mentions: Zhihua Ding Zhejiang University Peng Li
14. Motion correction using overlapped data correlation based on a spatial-spectral encoded parallel optical coherence tomography
  
  Explore OSA | OSA Publishing Mar 24 2017
  
  This paper presents an approach to remove motion artifacts based on a spatial-spectral encoded parallel OCT (SSE-POCT) system, where encoded rectangular illumination is employed. Motion artifacts within a B-scan are avoided due to parallel detection intrinsic to parallel OCT, while those between successive B-scans are estimated and corrected by a proposed overlapped data correlation (ODC) algorithm. To preserve axial resolution, decoded B-scan corresponding to complete spectrum is stitched from successive ...
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  Mentions: Zhihua Ding Zhejiang University Peng Li
15. Coagulation monitoring based on blood elastic measurement using optical coherence tomography
  
  Explore Conference Proceedings Mar 1 2017
  
  Blood coagulation monitoring is important to diagnose hematological diseases and cardiovascular diseases and to predict the risk of bleeding and excessive clotting. In this study, we developed a system to dynamically monitor blood coagulation and quantitatively determine the coagulation function by blood elastic measurement. When blood forms a clot from a liquid, ultrasonic force induces a shear wave, which is detected by optical coherence tomography (OCT). The coagulation of porcine ...
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  Mentions: Zhongping Chen UC Irvine Zhejiang University
16. A useful way to develop effective in vivo skin optical clearing agents
  
  Explore Wiley Online Library Dec 23 2016 Dermatology
  
  Skin optical clearing has shown tremendous potential in improving various optical imaging performances, but there is some certain blindness in screening out high-efficiency in vivo optical clearing methods. In this work, three optical clearing agents: sucrose (Suc), fructose (Fruc) and PEG-400 (PEG), and two chemical penetration enhancers: propylene glycol (PG) and thiazone (Thiaz) were used. PEG was firstly mixed with the two penetration enhancers, respectively, and then mixed with Fruc ...
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  Mentions: Zhihua Ding Zhejiang University Peng Li
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