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2. COMPARISON OF PROJECTION-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY-BASED METRICS FOR THE EARLY DETECTION OF RETINAL MICROVASCULAR IMPAIRMENTS IN DIABETES MELLITUS
  
  Explore LWW Online Oct 9 2019 Ophthalmology
  
  Purpose: To determine the ability of nonperfusion, vessel density , and morphologic measurements using projection-resolved optical coherence tomography angiography to detect early retinal microvasculature impairments in diabetes mellitus. Methods: A retrospective review was performed on Type 2 diabetes mellitus patients with no diabetic retinopathy (DR) or mild nonproliferative DR and age-matched controls imaged with optical coherence tomography angiography . Foveal avascular zone-related metrics and extrafoveal avascular area were measured in optical coherence ...
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  Mentions: Zhejiang University
3. Optical Coherence Tomography Angiography in Pinguecula and Pterygium
  
  Explore LWW Online Aug 27 2019 Ophthalmology
  
  Purpose: To investigate the density of conjunctival blood vessels in normal eyes and in eyes with pinguecula or pterygium . Methods: In this cross-sectional study, the conjunctival blood vessel density of 15 normal eyes, 15 pinguecula eyes, and 15 pterygium eyes of 43 healthy adults was assessed using optical coherence tomography angiography with an anterior segment lens adapter. The nasal surface of each eye (3 3 mm) was scanned 3 times ...
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  Mentions: Zhejiang University
4. Velocity range estimation for liquid flow based on optical micro-angiography
  
  Explore ScienceDirect Jun 25 2019
  
  Optical micro-angiography (OMAG) is widely used in vivo imaging due to its non-invasive and highly sensitive measurements. It can effectively distinguish flowing and stationary particles for applications such as micro-size blood vessel. However, the detectable flow velocity of OMAG is restricted by the system parameters. Their relationship is usually unknown and thus increase the difficulty of OMAG application on liquid flow measurements. This study for the first time proposes a ...
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  Mentions: Tsinghua University Zhejiang University Yonghong He
5. Improve depth of field of optical coherence tomography using finite energy Airy beam
  
  Explore OSA | OSA Publishing Jun 12 2019
  
  We report a technique to break the depth of field (DOF) limit in optical coherence tomography (OCT) using a finite energy Airy beam. The Airy beam is generated using a phase mask in a Fourier transform schematic and provides the DOF improvement due to its low diffraction. We compare Airy beam OCT with conventional Gaussian beam OCT using lateral resolution and sensitivity. Experimental data from the polystyrene beads in water ...
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  Mentions: Zhejiang University University of Missouri
6. Anterior Segment Biometry with Phenylephrine and Tropicamide during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography
  
  Explore Hindawi Publishing Corporation Feb 28 2019 Ophthalmology
  
  Purpose . To investigate the influence of phenylephrine and tropicamide on anterior segment biometry with ultralong scan depth optical coherence tomography (UL-OCT) during accommodation. Methods . In this study, 20 left eyes of healthy volunteers with a meanstandard deviation age of 31.055.84years and a mean refraction of 1.161.11 diopters (range 03.0D) were imaged using UL-OCT after instillation of artificial tears, phenylephrine, and tropicamide in three follow-up trials ...
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  Mentions: Zhejiang University Peng Li
7. The relation between optical coherence tomography-detected layered pattern and acute side branch occlusion after provisional stenting of coronary bifurcation lesions
  
  Explore ScienceDirect Jan 1 2019 Cardiology
  
  Background/Purpose. Layered pattern (presumed to be healed plaque after a thrombotic event) can be observed by optical coherence tomography (OCT). We sought to assess the ability of OCT-detected plaque composition to predict acute side branch (SB) occlusion after provisional bifurcation stenting. Methods This is a retrospective observational study using pre-intervention OCT in the main vessel to predict Thrombolysis in Myocardial Infarction (TIMI) flow grade 1 in a SB (diameter ...
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  Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz
8. Viscosity monitoring during hemodiluted blood coagulation using optical coherence elastography
  
  Explore IEEE Xplore Jun 5 2018
  
  Rapid and accurate clot diagnostic systems are needed for the assessment of hemodiluted blood coagulation. We develop a real-time optical coherence elastography (OCE) system, which measures the attenuation coefficient of a compressional wave induced by a piezoelectric transducer (PZT) in a drop of blood using optical coherence tomography (OCT), for the determination of viscous properties during the dynamic whole blood coagulation process. Changes in the viscous properties increase the attenuation ...
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  Mentions: UC Irvine Zhejiang University Jiang Zhu
9. Loquat Bruise Detection Using Optical Coherence Tomography Based on Microstructural Parameters
  
  Explore Home - Springer Apr 26 2018 NDE/NDT , Other Non-Medical
  
  Slight postharvest bruises of loquats remarkably affect the quality and shelf life of the fruits, but they are difficult to identify using visual inspection. Sub-surface structural changes in cells caused by mechanical injury or impact can be detected using spectroscopy-based methods from different angles. Optical coherence tomography (OCT), a non-destructive technology, can acquire cross-sectional images to analyze sub-surface structures of loquats, thus offering the potential to identify fruit bruises. This ...
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  Mentions: Zhejiang University
10. All-fiber probe for optical coherence tomography with an extended depth of focus by a high-efficient fiber-based filter
  
  Explore ScienceDirect Jan 5 2018 Probes
  
  Although methods have been proposed to maintain high transverse resolution over an increased depth range, it is not straightforward to scale down the bulk-optic solutions to minimized probes of optical coherence tomography (OCT). In this paper, we propose a high-efficient fiber-based filter in an all-fiber OCT probe to realize an extended depth of focus (DOF) while maintaining a high transverse resolution. Mode interference in the probe is exploited to modulate ...
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  Mentions: Zhihua Ding Zhejiang University Peng Li
11. Adaptive classifier allows enhanced flow contrast in OCT angiography using a histogram-based motion threshold and 3D Hessian analysis-based shape filtering
  
  Explore OSA | OSA Publishing Dec 8 2017
  
  In this Letter, we propose an adaptive digital classifier for flow contrast enhancement in optical coherence tomography angiography (OCTA). To solve the depth dependence in the initial motion-based classification, a depth-adaptive motion threshold was determined by performing a histogram analysis of an en-face image at each depth and identifying the static and dynamic voxel populations through fitting. In the follow-up shape-based classification, to adapt to the deformed vessel shapes in ...
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  Mentions: Zhejiang University Peking University Qiushi Ren
12. Noninvasive structural and microvascular anatomy of oral mucosae using handheld optical coherence tomography
  
  Explore OSA | OSA Publishing Oct 18 2017
  
  In this study, we demonstrated the feasibility of using a handheld optical coherence tomography (OCT) for in vivo visualizations of the microstructural and microvascular features of various oral mucosal types. To scan arbitrary locations of the oral mucosa, a scanning probe was developed, composed of a probe body fabricated by a 3D printer, miniaturized two-axis galvanometer, relay lenses, and reflective prism. With a 3D printing technique, the probe weight and ...
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  Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University
13. Phase and amplitude correction in polygon tunable laser-based optical coherence tomography
  
  Explore SPIE Digital Library Oct 10 2017
  
  Phase instability is a serious problem in swept-source optical coherence tomography (OCT) with polygon tunable lasers; however, these devices have additional issues. We found that polygon tunable lasers also have fluctuations in output power and sweep range: the former creates artifacts that may impair the recognition of sample information, and the latter reduces the interference signal utilization during phase correction. We demonstrate a method that uses the calibration signal to ...
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  Mentions: Zhejiang University
14. Spectral-domain optical coherence tomography dynamic changes and steroid response in multiple evanescent white dot syndrome
  
  Explore 欢迎访问国际眼科杂志编辑部 Sep 2 2017 Ophthalmology
  
  Dear Editor, Multiple evanescent white dot syndrome (MEWDS) was first described in 1984 as a rare, acute, unilateral, multifocal retinochoroidal disorder, typically affecting young myopic women[1]. Previous studies with fluorescein angiography (FA) and electrophysiology suggested that MEWDS to be a disease in the retinal pigment epithelium (RPE) or outer retina[2], while recent studies with spectraldomain optical coherence tomography (SD-OCT) suggested it may be an outer retinal disease due ...
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  Mentions: Zhejiang University
15. In Vivo Calcium Detection by Comparing Optical Coherence Tomography, Intravascular Ultrasound, and Angiography
  
  Explore ScienceDirect Aug 8 2017 Cardiology
  
  Objectives The aim of this study was to evaluate optical coherence tomography (OCT) and intravascular ultrasound (IVUS) versus coronary angiography in the assessment of target lesion calcification and its effect on stent expansion. Background IVUS is more sensitive than angiography in the detection of coronary artery calcium, but the relationship among IVUS, OCT, and angiography has not been studied. Methods Overall, 440 lesions (440 patients with stable angina) underwent OCT- ...
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  Mentions: Columbia University Cardiovascular Research Foundation Gary S. Mintz
16. Using Optical Coherence Tomography to Identify of Oral Mucosae with 3D-Printing Probe
  
  Explore Home - Springer Jul 22 2017
  
  Biomedical materials have different optical properties (e.g. absorption) for different wavelengths. Therefore, probing biomedical materials with multiple wavelengths not only can get in-depth understanding of the detected biomedical materials but also can differentiate the detected biomedical materials. To achieve this purpose, in this conference paper, we present our initial results of building up a portable multiple-wavelength biomedical sensing system. At this initial phase, we assembled this kind of system ...
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  Mentions: National Taiwan University Meng-Tsan Tsai Chang Gung University
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