1. Zhejiang University

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    1. Mentioned In 103 Articles

    2. Clinical determinants of coronary artery disease burden and vulnerability using optical coherence tomography co-registered with intravascular ultrasound

      Clinical determinants of coronary artery disease burden and vulnerability using optical coherence tomography co-registered with intravascular ultrasound
      Objectives: We investigated clinical determinants of disease burden and vulnerability using optical coherence tomography (OCT) co-registered with intravascular ultrasound (IVUS) in a large cohort of patients. Methods: A total of 704 patients [44.5% with acute coronary syndromes (ACS)] underwent coronary intervention. IVUS plaque burden and OCT lipid, macrophage and calcium indices and the presence of thrombus, plaque rupture and thin-cap fibroatheroma (TCFA) were analyzed. Results: Median patient age was ...
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    3. Subcutaneous sweat pore estimation from optical coherence tomography

      Subcutaneous sweat pore estimation from optical coherence tomography
      Sweat pore, one of the level 3 features of fingerprint, has attracted much attention in fingerprint recognition. Traditional sweat pores on surface fingerprint are unclear or blurred when fingers are stained or damaged. Subcutaneous sweat pores, as cross section of the sweat glands, are resistant to external interferences. With 3D fingertip information measured by optical coherence tomography (OCT), the subcutaneous sweat pore estimation from OCT volume data is investigated. First ...
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    4. Attention Based Deep Learning System for Automated Diagnoses of Age-Related Macular Degeneration in Optical Coherence Tomography Images

      Attention Based Deep Learning System for Automated Diagnoses of Age-Related Macular Degeneration in Optical Coherence Tomography Images
      Purpose The progression of age-related macular degeneration (AMD) is critical to treatment decisions in clinical practice. The disease can be classified into four categories namely, drusen, inactive choroidal neovascularization (CNV), active CNV, and normal, according to severity based on optical coherence tomography (OCT) images. Interpreting numerous OCT images is still time-consuming and labor-intensive, especially for the detection of the CNV activity. To address this problem, we developed a deep learning ...
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    5. In vivo non-contact measurement of human iris elasticity by optical coherence elastography

      In vivo non-contact measurement of human iris elasticity by optical coherence elastography
      Quantifying the mechanical properties of the iris can offer valuable insights into the pathophysiology of primary angle closure glaucoma (PACG). However, current techniques for iris elastography remain ex vivo with limited clinical applications. This article describes a proposition for a non-contact and non-invasive air-puff Optical coherence elastography (OCE) system that can evaluate iris elasticity in vivo. Ten eyes recruited from seven subjects underwent OCE imaging acquisition under three different illumination ...
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    6. Optical Coherence Tomography Angiography-Based Quantitative Assessment of Morphologic Changes in Active Myopic Choroidal Neovascularization During Anti-vascular Endothelial Growth Factor Therapy

      Optical Coherence Tomography Angiography-Based Quantitative Assessment of Morphologic Changes in Active Myopic Choroidal Neovascularization During Anti-vascular Endothelial Growth Factor Therapy
      Purpose: To establish quantitative profile of the morphologic changes among patients with active myopic choroidal neovascularization (mCNV) before and after anti-vascular endothelial growth factor (VEGF) therapy using optical coherence tomography angiography (OCTA) to assess the therapeutic response. Methods: Patients with active mCNV who received anti-VEGF injections between February 2017 to October 2020 and fit the study criteria were retrospectively reviewed. Quantitative analysis of their OCTA images were carried out to ...
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    7. Feasibility Study of Detecting Plum’s Early Mechanical Injury Based on Optical Coherence Tomography and Cell Morphological Parameters

      Feasibility Study of Detecting Plum’s Early Mechanical Injury Based on Optical Coherence Tomography and Cell Morphological Parameters
      Mechanical injury, which is hardly observed by naked eyes and machine vision technique if the epidermis of the plum is not ruptured, tends to be the main cause of the shorten shelf life and decay of plums. For the purpose of non-destructive discriminate the mechanical injury, this study proposes to apply optical coherence tomography (OCT) to conduct 3D observation to plums subcutaneous tissues, and to automatically compute the tissues morphological ...
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    8. Higher choroidal thickness and lower choriocapillaris blood flow signal density based on optical coherence tomography angiography in diabetics

      Higher choroidal thickness and lower choriocapillaris blood flow signal density based on optical coherence tomography angiography in diabetics
      Diabetes mellitus (DM) is one of the fastest growing chronic diseases in the world and one of the main causes of vision loss. Whether or not diabetic choroidopathy (DC) is involved in the initiation and progression of diabetic ocular complications needs to be explored. We included 54 diabetic eyes from 36 diabetic patients, and 54 healthy eyes from 32 control subjects after propensity scores matching. All of the subjects were ...
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    9. Automatic 3D adaptive vessel segmentation based on linear relationship between intensity and complex-decorrelation in optical coherence tomography angiography

      Automatic 3D adaptive vessel segmentation based on linear relationship between intensity and complex-decorrelation in optical coherence tomography angiography
      Background: Vascular quantitative metrics have been widely used in the preclinical studies and clinical applications (e.g., the diagnosis and treatment of port wine stain, PWS), which require accurate vessel segmentation. An automatic 3D adaptive vessel segmentation is in need for a reproducible and objective quantification of the optical coherence tomography angiography (OCTA) image. Methods: Human skin imaging was performed with a lab-built optical coherence tomography (OCT) system. Rather than ...
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    10. Recent progress of nondestructive techniques for fruits damage inspection: a review

      Recent progress of nondestructive techniques for fruits damage inspection: a review
      In the process of growing, harvesting, and storage, fruits are vulnerable to mechanical damage , microbial infections, and other types of damage , which not only reduce the quality of fruits , increase the risk of fungal infections, in turn greatly affect food safety, but also sharply reduce economic benefits. Hence, it is essential to identify damaged fruits in time. Rapid and nondestructive detection of fruits damage is in great demand. In this ...
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    11. High performance OCTA enabled by combining features of shape, intensity, and complex decorrelation

      High performance OCTA enabled by combining features of shape, intensity, and complex decorrelation
      Motion contrast optical coherence tomography angiography (OCTA) entails a precise identification of dynamic flow signals from the static background, but an intermediate region with voxels exhibiting a mixed distribution of dynamic and static scatterers is almost inevitable in practice, which degrades the vascular contrast and connectivity. In this work, the static-dynamic intermediate region was pre-defined according to the asymptotic relation between inverse signal-to-noise ratio (iSNR) and decorrelation, which was theoretically ...
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    12. Fast simulation and design of the fiber probe with a fiber-based pupil filter for optical coherence tomography using the eigenmode expansion approach

      Fast simulation and design of the fiber probe with a fiber-based pupil filter for optical coherence tomography using the eigenmode expansion approach
      Fiber probes for optical coherence tomography (OCT) recently employ a short section of step-index multimode fiber (SIMMF) to generate output beams with extended depth of focus (DOF). As the focusing region of the output beam is generally close to the probe end, it is not feasible to adopt the methods for bulk-optics with spatial pupil filters to the fiber probes with fiber-based filters. On the other hand, the applicable method ...
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    13. Novel endoscopic optical diagnostic technologies in medical trial research: recent advancements and future prospects

      Novel endoscopic optical diagnostic technologies in medical trial research: recent advancements and future prospects
      Novel endoscopic biophotonic diagnostic technologies have the potential to non-invasively detect the interior of a hollow organ or cavity of the human body with subcellular resolution or to obtain biochemical information about tissue in real time. With the capability to visualize or analyze the diagnostic target in vivo, these techniques gradually developed as potential candidates to challenge histopathology which remains the gold standard for diagnosis. Consequently, many innovative endoscopic diagnostic ...
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    14. Comparison of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and total cholesterol/high-density lipoprotein cholesterol for the prediction of thin-cap fibroatheroma determined by intravascular optical coherence tomography

      Comparison of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and total cholesterol/high-density lipoprotein cholesterol for the prediction of thin-cap fibroatheroma determined by intravascular optical coherence tomography
      Background The correlation among the ratios of low-density lipoprotein cholesterol/high-density lipoprotein cholesterol (LDL-C/ HDL-C), total cholesterol/high-density lipoprotein cholesterol (TC/HDL-C) and thin-cap fibroatheroma has not yet been established. Methods It was a single center, retrospective observational study. In total, we recruited 421 patients (82.4% men; mean age 65.73 10.44 years) with one culprit vessel which determined by intravascular optical coherence tomography (OCT). The thinnest-capped fibroatheroma ...
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    15. Characterisation of macular superficial vessel density alteration in preclinical ethambutol-induced optic neuropathy using optical coherence tomography angiography

      Characterisation of macular superficial vessel density alteration in preclinical ethambutol-induced optic neuropathy using optical coherence tomography angiography
      Aim To investigate the changes in macular vessel density (mVD) and its relationship to macular ganglion cellinner plexiform layer (mGCIPL) thickness in patients receiving ethambutol (EMB) therapy for tuberculosis without recognisable clinical symptoms or signs of EMB-induced optic neuropathy (EON). Methods A total of 23 eyes of 13 patients using EMB therapy for 6 months without EON (preclinical EON) as the EMB group, 40 eyes of 23 healthy individuals as ...
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  2. About Zhejiang University

    Zhejiang University

    Zhejiang University, sometimes referred to as Zheda, is a national university in China. Founded in 1897, Zhejiang University is one of China's oldest and most prestigious institutions of higher education. Zhejiang University is located approximately 112 miles (180 km) southwest of Shanghai in the city of Hangzhou, Zhejiang Province. Zhejiang University Library collection contains about 6.9 million volumes, making it one of the largest academic libraries in the country. The university focuses on both undergraduate and graduate education.