1. Zhejiang University

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    1. Mentioned In 117 Articles

    2. New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography

      New insights into fibrous cap thickness of vulnerable plaques assessed by optical coherence tomography
      Objective: Vulnerable plaques with fibrous cap thickness (FCT) of 65 m are prone to rupture and/or thrombosis. However, plaques with FCT 65 m cause acute myocardial infarction and even sudden death. We aimed to investigate the relationship between 65 FCT 80 m and plaque rupture and/or thrombosis using optical coherence tomography (OCT). Methods: OCT was performed on culprit lesions in 502 consecutively enrolled patients to identify FCT. Patients ...
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    3. Three-dimensional optical coherence digital-null deformography of multi-refractive-surface optics with nanometer sensitivity

      Three-dimensional optical coherence digital-null deformography of multi-refractive-surface optics with nanometer sensitivity
      Knowledge of the lens deformation during the reliability test is critical for lens design and fabrication. Refractive surface distorts the optical path of probing light, and poses a great challenge to measuring the test-induced nanoscale changes of all refractive lens surfaces simultaneously. In this work, we present an optical coherence digital-null deformography (ODD). A digital null, i.e., the interference signals (including intensity and phase) of the backscattered probing light ...
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    4. Analysis of macular microvasculature with optical coherence tomography angiography for migraine: A systematic review and meta-analysis

      Analysis of macular microvasculature with optical coherence tomography angiography for migraine: A systematic review and meta-analysis
      Objective: This study aimed to evaluate the features of macular microvasculature with optical coherence tomography angiography (OCTA) among migraine patients. Methods: We systematically searched PubMed, Web of Science, Embase, and Cochrane Library for studies that evaluated the macular microvasculature of migraine patients. The weighted mean differences (WMDs) of the foveal avascular zone (FAZ), foveal superficial capillary plexus (SCP) vessel density (VD), parafoveal SCP VD, foveal deep capillary plexus (DCP) VD ...
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    5. Development of a deep learning algorithm for myopic maculopathy classification based on OCT images using transfer learning

      Development of a deep learning algorithm for myopic maculopathy classification based on OCT images using transfer learning
      Purpose: To apply deep learning (DL) techniques to develop an automatic intelligent classification system identifying the specific types of myopic maculopathy (MM) based on macular optical coherence tomography (OCT) images using transfer learning (TL). Method: In this retrospective study, a total of 3,945 macular OCT images from 2,866 myopic patients were recruited from the ophthalmic outpatients of three hospitals. After culling out 545 images with poor quality, a ...
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    6. Detecting vulnerable carotid plaque and its component characteristics: Progress in related imaging techniques

      Detecting vulnerable carotid plaque and its component characteristics: Progress in related imaging techniques
      Carotid atherosclerotic plaque rupture and thrombosis are independent risk factors for acute ischemic cerebrovascular disease. Timely identification of vulnerable plaque can help prevent stroke and provide evidence for clinical treatment. Advanced invasive and non-invasive imaging modalities such as computed tomography, magnetic resonance imaging, intravascular ultrasound, optical coherence tomography, and near-infrared spectroscopy can be employed to image and classify carotid atherosclerotic plaques to provide clinically relevant predictors used for patient risk ...
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    7. OCT-Based Biomarkers are Associated with Systemic Inflammation in Patients with Treatment-Naïve Diabetic Macular Edema

      OCT-Based Biomarkers are Associated with Systemic Inflammation in Patients with Treatment-Naïve Diabetic Macular Edema
      Introduction: Diabetic macular edema (DME) is one of the major sight-threatening complications of diabetic retinopathy, which is associated with retinal inflammation. However, it is still unknown whether DME is associated with systemic inflammation. The study aimed to investigate the association between systemic inflammatory and optical coherence tomography (OCT) biomarkers in patients with treatment-nave center-involving diabetic macular edema (DME) and to further explore the role of systemic inflammation in DME. Methods ...
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    8. Correlation Between Serum Uric Acid Levels and Coronary Plaque Characteristics on Optical Coherence Tomography

      Correlation Between Serum Uric Acid Levels and Coronary Plaque Characteristics on Optical Coherence Tomography
      Elevated serum uric acid (sUA) is associated with increasing risk of coronary heart disease (CHD). However, existing research is limited by potential confounders. Herein, our study aims to probe the association between sUA levels and the morphological characteristics of coronary plaque by a propensity score matching (PSM) analysis.All 420 patients with CHD who had undergone optical coherence tomography of culprit lesions were included. Eligible patients were assigned into 2 ...
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    9. Retinal Structure Detection in OCTA Image via Voting-based Multi-task Learning

      Retinal Structure Detection in OCTA Image via Voting-based Multi-task Learning
      Automated detection of retinal structures, such as retinal vessels (RV), the foveal avascular zone (FAZ), and retinal vascular junctions (RVJ), are of great importance for understanding diseases of the eye and clinical decision-making. In this paper, we propose a novel Voting-based Adaptive Feature Fusion multi-task network (VAFF-Net) for joint segmentation, detection, and classification of RV, FAZ, and RVJ in optical coherence tomography angiography (OCTA). A task-specific voting gate module is ...
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    10. Evaluation of retinal vessel and perfusion density in migraine patients by optical coherence tomography angiography

      Evaluation of retinal vessel and perfusion density in migraine patients by optical coherence tomography angiography
      Background: Migraine is a neurovascular disease and has been reported as a risk factor for ocular vascular complications. Our study aimed to compare the retinal vessel density and perfusion density between migraine patients and healthy subjects by optical coherence tomography angiography (OCTA). Methods: In this prospective study, 23 patients with migraine with aura (MWA) and 31 patients with migraine without aura (MWOA), and 32 age- and gender-matched healthy controls (HC ...
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    11. OCT biomarkers related to subthreshold micropulse laser treatment effect in central serous chorioretinopathy

      OCT biomarkers related to subthreshold micropulse laser treatment effect in central serous chorioretinopathy
      Background: To identify the OCT biomarkers related to the anatomical outcomes in eyes with central serous chorioretinopathy (CSCR) after subthreshold micropulse laser (SML) treatment. Methods: Patients with CSCR underwent SML were enrolled in this retrospective study. Only patients who underwent enhanced depth imaging optical coherence tomography (EDI-OCT) examination before and after SML were selected. Patients were divided into two groups based on whether subretinal fluid (SRF) absorbed or not after ...
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    12. Endoscopic optical coherence tomography angiography using inverse SNR-amplitude decorrelation features and electrothermal micro-electro-mechanical system raster scan

      Endoscopic optical coherence tomography angiography using inverse SNR-amplitude decorrelation features and electrothermal micro-electro-mechanical system raster scan
      Background: Angiogenesis is closely associated with tumor development and progression. Endoscopic optical coherence tomography angiography (OCTA) enables rapid inspection of mucosal 3D vasculature of inner organs in the early-stage tumor diagnosis; however, it is limited by instabilities of the optical signal and beam scanning. Methods: In the phase-unstable swept source OCTA (SS-OCTA), amplitude decorrelation was used to compute the motion-induced changes as motion contrast. The influence of the random noise-induced ...
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    13. Novel Findings of Retinal and Choroidal Features Utilizing Optical Coherence Tomography Angiography Analysis in Patients With Autoimmune Posterior Uveitis

      Novel Findings of Retinal and Choroidal Features Utilizing Optical Coherence Tomography Angiography Analysis in Patients With Autoimmune Posterior Uveitis
      Purpose: To analyze the quantitative parameters acquired by optical coherence tomography angiography (OCTA) in patients with autoimmune posterior uveitis. Methods: OCTA images of 65 eyes affected with uveitis and 65 normal control (NC) eyes were obtained. The central macular thickness (CMT), retinal thicknesses, foveal avascular zone (FAZ) area, foveal density 300 m (FD300), and vascular density (VD) were compared among acute uveitic eyes, chronic uveitic eyes, and NC eyes. VDs ...
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    14. Optimized number of the primary singular values for image reconstruction in reflection matrix based optical coherence tomography

      Optimized number of the primary singular values for image reconstruction in reflection matrix based optical coherence tomography
      A reflection matrix based optical coherence tomography (OCT) is recently proposed and expected to extend the imaging-depth limit twice. However, the imaging depth and hence the image quality heavily depend on the number of primary singular values considered for image reconstruction. To this regard, we propose a method based on correlation between image pairs reconstructed from different number of singular values and corresponding remainders. The obtained correlation curve and another ...
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    15. Outer Macular Microvascular Supply in Retinitis Pigmentosa Examined using Optical Coherence Tomography Angiography

      Outer Macular Microvascular Supply in Retinitis Pigmentosa Examined using Optical Coherence Tomography Angiography
      Purpose . To determine the vessel density of the superior (SCP) and deep retinal capillary plexuses (DCP) in patients with retinitis pigmentosa (RP) using optical coherence tomography angiography (OCTA). Methods . This was a cross-sectional study. A total of 25 eyes of 25 healthy volunteers and 30 eyes of 17 patients with RP were evaluated in this study. The integrity of the ellipsoid zone in the macular fovea was evaluated as an ...
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    16. Clinical determinants of coronary artery disease burden and vulnerability using optical coherence tomography co-registered with intravascular ultrasound

      Clinical determinants of coronary artery disease burden and vulnerability using optical coherence tomography co-registered with intravascular ultrasound
      Objectives: We investigated clinical determinants of disease burden and vulnerability using optical coherence tomography (OCT) co-registered with intravascular ultrasound (IVUS) in a large cohort of patients. Methods: A total of 704 patients [44.5% with acute coronary syndromes (ACS)] underwent coronary intervention. IVUS plaque burden and OCT lipid, macrophage and calcium indices and the presence of thrombus, plaque rupture and thin-cap fibroatheroma (TCFA) were analyzed. Results: Median patient age was ...
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  2. About Zhejiang University

    Zhejiang University

    Zhejiang University, sometimes referred to as Zheda, is a national university in China. Founded in 1897, Zhejiang University is one of China's oldest and most prestigious institutions of higher education. Zhejiang University is located approximately 112 miles (180 km) southwest of Shanghai in the city of Hangzhou, Zhejiang Province. Zhejiang University Library collection contains about 6.9 million volumes, making it one of the largest academic libraries in the country. The university focuses on both undergraduate and graduate education.