1. Yves T. Wang

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    1. Mentioned In 10 Articles

    2. Mapping conduction velocity of early embryonic hearts with a robust fitting algorithm

      Mapping conduction velocity of early embryonic hearts with a robust fitting algorithm
      Cardiac conduction maturation is an important and integral component of heart development. Optical mapping with voltage-sensitive dyes allows sensitive measurements of electrophysiological signals over the entire heart. However, accurate measurements of conduction velocity during early cardiac development is typically hindered by low signal-to-noise ratio (SNR) measurements of action potentials. Here, we present a novel image processing approach based on least squares optimizations, which enables high-resolution, low-noise conduction velocity mapping of ...
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    3. Capturing structure and function in an embryonic heart with biophotonic tools

      Capturing structure and function in an embryonic heart with biophotonic tools
      Disturbed cardiac function at an early stage of development has been shown to correlate with cellular/molecular, structural as well as functional cardiac anomalies at later stages culminating in the congenital heart defects (CHDs) that present at birth. While our knowledge of cellular and molecular steps in cardiac development is growing rapidly, our understanding of the role of cardiovascular function in the embryo is still in an early phase. One ...
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    4. Three-dimensional correction of conduction velocity in the embryonic heart using integrated optical mapping and optical coherence tomography

      Three-dimensional correction of conduction velocity in the embryonic heart using integrated optical mapping and optical coherence tomography
      ...late the structure and electrophysiology, thereby improving our understanding of heart development. Pei Ma ; Yves T. Wang ; Shi Gu ; Michiko Watanabe ; Michael W. Jenkins, et al. "Three-dimensional correction of conduc...
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    5. Apparatus for low coherence optical imaging

      Apparatus for low coherence optical imaging
      The present invention relates to an apparatus for low coherence optical imaging, and more particularly to an apparatus for low coherence optical imaging which can obtain the information of the different depths of a sample simultaneously. The apparatus comprises a phase transformation unit or a beam shift unit. The phase transformation unit or beam shift unit transforms and reflects the reference light, such that the reflected reference light comprises different ...
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    6. Optical imaging apparatus and method

      Optical imaging apparatus and method
      The present invention relates to an optical imaging apparatus and a method, and more particularly to an optical imaging apparatus and a method with short coherence length optical source. The apparatus comprises an optical source with a plurality of outputs for providing a reference light and a sample light; a sample probe module for leading the sample light to a sample, and leading an information light out; an interference module ...
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    7. Cell death detection by quantitative three-dimensional single-cell tomography

      Cell death detection by quantitative three-dimensional single-cell tomography
      Ultrahigh-resolution optical coherence tomography (UR-OCT) has been used for the first time to our knowledge to study single-cell basal cell carcinoma (BCC) in vitro. This noninvasive, in situ, label-free technique with deep imaging depth enables three-dimensional analysis of scattering properties of single cells with cellular spatial resolution. From three-dimensional UR-OCT imaging, live and dead BCC cells can be easily identified based on morphological observation. We developed a novel method to ...
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    8. Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea

      Feature Of The Week 4/4/10: Ce3+:YAG double-clad crystal fiber based optical coherence tomography on fish cornea
      Feature Of The Week 4/4/10: With the tremendous success of optical coherence tomography (OCT) in recent years, high resolution and high image fidelity are getting more importance. So far, several approaches have been proposed to achieve high axial resolution, such as multiplexed superluminescent diode, femtosecond laser, continuum generation from photonic crystal fiber, and xenon illuminator. In general, these solutions are either have high cost, exhibit bumpy spectrum, or ...
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  2. About Yves T. Wang

    Yves T. Wang is in the Department of Biomedical Engineering at the Case Western Reserve University.