1. Yusuke Fujino

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    1. Mentioned In 28 Articles

    2. Association of skin autofluorescence with plaque vulnerability evaluated by optical coherence tomography in patients with cardiovascular disease

      Association of skin autofluorescence with plaque vulnerability evaluated by optical coherence tomography in patients with cardiovascular disease
      Background and aims Accumulation of advanced glycation end products (AGEs) can be measured non-invasively by skin autofluorescence (SAF) whose values are elevated in patients with cardiovascular disease (CVD). Optical coherence tomography (OCT) is an intravascular imaging modality that could allow visualization of plaque composition. We aim to examine the relationship between SAF and plaque composition evaluated by frequency-domain OCT in patients with CVD. Methods We prospectively enrolled 108 patients with ...
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    3. One-year follow-up optical coherence tomography after endovascular treatment with a new-generation zotarolimus-eluting stent for chronic mesenteric ischemia

      One-year follow-up optical coherence tomography after endovascular treatment with a new-generation zotarolimus-eluting stent for chronic mesenteric ischemia
      A 62-year-old man experienced lower abdominal pain triggered by a hypotensive episode during hemodialysis for end-stage renal failure. Computed tomography scan and subsequent angiography revealed a significant calcified stenosis at the proximal part of inferior mesenteric artery (IMA) ( Fig. 1 A-C). Abdominal angina was diagnosed and his symptoms were reproduced during intentional hypotension induced by intravenous administration of calcium channel blocker with drop in the Pd/Pa within the IMA ...
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      Mentions: Yusuke Fujino
    4. Difference in Vascular Response between Sirolimus-eluting- and Everolimus-eluting Stents in Ostial Left Circumflex Artery after Unprotected Left Main as Observed by

      Difference in Vascular Response between Sirolimus-eluting- and Everolimus-eluting Stents in Ostial Left Circumflex Artery after Unprotected Left Main as Observed by
      Background Kissing-balloon technique (KBT) is commonly performed during percutaneous coronary intervention of distal unprotected left main coronary artery (ULM) aiming at obtaining optimal opening of the side branch (left circumflex artery; LCX) ostium. Nonetheless, detailed evaluation of vascular response to stents in LCX ostium is lacking. We therefore evaluated the vascular response to different drug-eluting stents (DES) in ostial LCX after ULM by means of optical coherence tomography (OCT). Methods ...
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    5. Three-dimensional registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      Three-dimensional registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation
      Evidence suggests high-resolution, high-contrast, 100 frames / s 100frames/s intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and three-dimensional (3-D) registration methods to provide validation of IVOCT pullback volumes using microscopic, color, and fluorescent cryo-image volumes with optional registered cryo-histology. A specialized registration method matched IVOCT pullback images acquired in the catheter reference frame to a ...
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    6. Optical coherence tomography assessment of in-stent restenosis after percutaneous coronary intervention with two-stent technique in unprotected left main

      Optical coherence tomography assessment of in-stent restenosis after percutaneous coronary intervention with two-stent technique in unprotected left main
      Background Optical coherence tomography (OCT) has contributed to a better understanding of in-stent restenosis (ISR); however, studies evaluating ISR pattern after two-stent technique in unprotected left main (ULM) are lacking. We aim to evaluate the ISR pattern of proximal LAD and LCX after two-stent technique in ULM. Methods We performed OCT in 26 patients with isolated or combined ISR (identified by angiography as 50%) after two stent implantation in the ...
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    7. 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation
      High resolution, 100 frames/sec intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and 3D registration methods, to provide validation of IVOCT pullback volumes using microscopic, brightfield and fluorescent cryoimage volumes, with optional, exactly registered cryo-histology. The innovation was a method to match an IVOCT pullback images, acquired in the catheter reference frame, to a true ...
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    8. Extremely Late Catch-Up Phenomenon After First-Generation Sirolimus-Eluting Stent in the Left Main Stem : Insights From Optical Coherence Tomography

      Extremely Late Catch-Up Phenomenon After First-Generation Sirolimus-Eluting Stent in the Left Main Stem : Insights From Optical Coherence Tomography
      A72-year-old man had undergone angioplasty of the left main stem (LMS) with an implantation of a first-generation drug-eluting stent (DES) (3.5 18-mm Cypher stent, Cordis, Johnson Johnson, Bridgewater, New Jersey) (Figure 1A). Post-procedural intravascular ultrasound (IVUS) had shown a well-expanded stent (Figures 1A0 and 1Aac). Four years later, both angiography and IVUS exhibited no significant in-stent restenosis (ISR) or stent recoil (Figures 1B, 1B0 , and 1Ba0 c0 ). At 7 ...
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    9. Extremely Late Catch-Up Phenomenon After First-Generation Sirolimus-Eluting Stent in the Left Main Stem

      Extremely Late Catch-Up Phenomenon After First-Generation Sirolimus-Eluting Stent in the Left Main Stem
      A 72-year-old man had undergone angioplasty of the left main stem (LMS) with an implantation of a first-generation drug-eluting stent (DES) (3.5 18-mm Cypher stent, Cordis, Johnson Johnson, Bridgewater, New Jersey) ( Figure 1A ). Post-procedural intravascular ultrasound (IVUS) had shown a well-expanded stent ( Figures 1A and 1Aac ). Four years later, both angiography and IVUS exhibited no significant in-stent restenosis (ISR) or stent recoil ( Figures 1B, 1B, and 1Bac ). At 7 ...
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    10. A Honeycomb-Like Structure in Chronic Total Occlusion Demonstrated by Frequency-Domain Optical Coherence Tomography

      A Honeycomb-Like Structure in Chronic Total Occlusion Demonstrated by Frequency-Domain Optical Coherence Tomography
      ...re in Chronic Total Occlusion Demonstrated by Frequency-Domain Optical Coherence Tomography Yusuke Fujino x Yusuke Fujino Search for articles by this author Affiliations * New Tokyo Hospital, Chiba, Japan Corresp...
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    11. 3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search

      3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search
      Worldwide, many hundreds of thousands of stents are implanted each year to revascularize occlusions in coronary arteries. Intravascular optical coherence tomography (OCT) is an important emerging imaging technique, which has the resolution and contrast necessary to quantitatively analyze stent deployment and tissue coverage following stent implantation. Automation is needed, as current, it takes up to 16 hours to manually analyze hundreds of images and thousands of stent struts from a ...
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    12. New Insights on acute expansion and longitudinal elongation of bioresorbable vascular scaffolds In-Vivo and at bench test: A note of caution on reliance to compliance charts and nominal length

      New Insights on acute expansion and longitudinal elongation of bioresorbable vascular scaffolds In-Vivo and at bench test: A note of caution on reliance to compliance charts and nominal length
      ..., PhD^1,3,*, 4. Bruno Francaviglia MD^1, 5. Carmelo Grasso MD^1, 6. Carmelo Sgroi MD^1, 7. Wei Wang PhD^5, 8. Yusuke Fujino MD^6, 9. Stephen J. Ganocy PhD^7, 10. Giovanni Longo MD^1, 11. Claudia I. Tamburino MD^1, 12. Ma...
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    13. Impact of Main-Branch Calcified Plaque on Side-Branch Stenosis in Bifurcation Stenting: An Optical Coherence Tomography Study

      Impact of Main-Branch Calcified Plaque on Side-Branch Stenosis in Bifurcation Stenting: An Optical Coherence Tomography Study
      ...aque on Side-Branch Stenosis in Bifurcation Stenting: An Optical Coherence Tomography Study Yusuke Fujino x Yusuke Fujino Search for articles by this author Affiliations * Department of Cardiology, New Tokyo Hospit...
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    14. Intravascular Frequency-Domain Optical Coherence Tomography Assessment of Carotid Artery Disease in Symptomatic and Asymptomatic Patients

      Intravascular Frequency-Domain Optical Coherence Tomography Assessment of Carotid Artery Disease in Symptomatic and Asymptomatic Patients
      Objectives The goal of this study was to investigate carotid plaque characteristics in symptomatic versus asymptomatic patients with the use of nonocclusive optical coherence tomography (OCT). Background The identification of asymptomatic patients with carotid disease who are at risk of stroke remains a challenge. There is an increasing awareness that plaque characteristics may best risk-stratify this population. We hypothesized that OCT, a new high-resolution (10 m) imaging modality, might be ...
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  2. About Yusuke Fujino

    Yusuke Fujino is at the Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio  and Department of Cardiology, New Tokyo Hospital, Chiba, Japan.