1. Yoshiaki Yasuno

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    1. Mentioned In 125 Articles

    2. Full-range ultrahigh-resolution spectral-domain optical coherence tomography in 1.7 µm wavelength region for deep-penetration and high-resolution imaging of turbid tissues

      Full-range ultrahigh-resolution spectral-domain optical coherence tomography in 1.7 µm wavelength region for deep-penetration and high-resolution imaging of turbid tissues
      For the first time, we developed a full-range ultrahigh-resolution (UHR) spectral-domain optical coherence tomography (SD-OCT) technique working in the 1.7 m wavelength region. This technique allowed high-resolution, deep-tissue imaging. By using a supercontinuum source operating at a wavelength of 1.7 m, an axial resolution of 3.6 m in a tissue specimen was achieved. To enhance the imaging depth of UHR-SD-OCT, we performed full-range OCT imaging based on ...
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    3. Quantitative Evaluation of Phase Retardation in Filtering Blebs Using Polarization-Sensitive Optical Coherence Tomography

      Quantitative Evaluation of Phase Retardation in Filtering Blebs Using Polarization-Sensitive Optical Coherence Tomography
      Purpose : Polarization-sensitive optical coherence tomography (PS-OCT) can detect and evaluate scar fibrosis of the filtering blebs after glaucoma surgery. Although the change in phase retardation reportedly reflects bleb function, quantitative assessment of phase retardation in ocular tissues has not been conducted. We aimed to establish quantitative methods to investigate changes in phase retardation in the blebs after surgery using PS-OCT. Methods : Twenty-two blebs of 22 patients who had undergone glaucoma ...
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    4. Program for correcting data measured by PS-OCT and PS-OCT system equipped with the program

      Program for correcting data measured by PS-OCT and PS-OCT system equipped with the program
      Data measured by PS-OCT is corrected in a non-linear manner to enhance the quantitative analysis capability of PS-OCT and permit accurate quantitative diagnosis, including diagnosis of disease stage of lesions, as a useful means for computer diagnosis. Even when retardation per PS-OCT 1 contains error and becomes noise and its distribution is not normal or symmetrical around the true value, measured data is converted using a distribution conversion function obtained ...
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    5. Investigation of Thermal Effects of Photocoagulation on Retinal Tissue Using Fine-Motion-Sensitive Dynamic Optical Coherence Tomography

      Investigation of Thermal Effects of Photocoagulation on Retinal Tissue Using Fine-Motion-Sensitive Dynamic Optical Coherence Tomography
      ...con Corp, Tomey Corp., Canon, and patent-license to Tomey Corp. In addition, Toyohiko Yatagai, Masahide Itoh, Yoshiaki Yasuno received a Japanese patent P2007-101365A for “Method for calibration of a spectral optical coh...
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    6. Swept source optical coherence tomography and method for stabilizing phase thereof

      Swept source optical coherence tomography and method for stabilizing phase thereof
      In an embodiment, a computer 16, which generates tomographic images based on spectral interference signals detected by a light detector 15 from overlaid reference light emitted by a swept-source type light source 2 of a SS-OCT, split, and then reflected by a fixed reference mirror 8 on one hand and object light reflected by an object to be measured 6 on the other, is caused to function to apply rough ...
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    7. Objective Evaluation of Functionality of Filtering Bleb Based on Polarization-Sensitive Optical Coherence Tomography

      Objective Evaluation of Functionality of Filtering Bleb Based on Polarization-Sensitive Optical Coherence Tomography
      Purpose : The fibrosis score is a new diagnostic score that we have developed to evaluate the function of bleb structures after glaucoma filtration surgery using polarization-sensitive optical coherence tomography (PS-OCT). This study aims to assess the efficacy of the fibrosis score in discriminating nonfunctional from the functional blebs. Methods : A total of 20 patients who had undergone glaucoma filtration surgery were imaged at different time periods after surgery using PS-OCT ...
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    8. Eye motion corrected OCT imaging with Lissajous scan pattern

      Eye motion corrected OCT imaging with Lissajous scan pattern
      Ophthalmic optical coherence tomography (OCT) is a powerful tool which provides high resolution three dimensional (3D) volumetric image of human retina. However, the measurement data of OCT suffer motion artifact due to the involuntary eye motion during data acquisition. To eliminate this motion artifact and provide the true shape of retinal image, an eye motion corrected OCT imaging method based on Lissajous scan pattern is proposed in this paper. In ...
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    9. Quantitative optical coherence tomography by maximum a-posteriori estimation of signal intensity

      Quantitative optical coherence tomography by maximum a-posteriori estimation of signal intensity
      A maximum a-posteriori (MAP) estimator for signal amplitude of optical coherence tomography (OCT) is presented. This estimator provides an accurate and low bias estimation of the correct OCT signal amplitude even at very low signal-tonoise ratios. As a result, contrast improvement of retinal OCT images is demonstrated. In addition, this estimation method allows for an estimation reliability to be calculated. By combining the MAP estimator with a previously demonstrated attenuation ...
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    10. Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography

      Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography
      Quantitative evaluation of optical properties of choroid and sclera are performed by multifunctional optical coherence tomography. Five normal eyes, five glaucoma eyes and one choroidal atrophy eye are examined. The refractive error was found to be correlated with choroidal birefringence, polarization uniformity, and flow in addition to scleral birefringence among normal eyes. The significant differences were observed between the normal and the glaucoma eyes, as for choroidal polarization uniformity, flow ...
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    11. Three-dimensional multifunctional optical coherence tomography for skin imaging

      Three-dimensional multifunctional optical coherence tomography for skin imaging
      Optical coherence tomography (OCT) visualizes cross-sectional microstructures of biological tissues. Recent developments of multifunctional OCT (MF-OCT) provides multiple optical contrasts which can reveal currently unknown tissue properties. In this contribution we demonstrate multifunctional OCT specially designed for dermatological investigation. And by utilizing it to measure four different body parts of in vivo human skin, three-dimensional scattering OCT, OCT angiography, polarization uniformity tomography, and local birefringence tomography images were obtained by ...
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    12. Maximum a posteriori estimator for high-contrast image composition of optical coherence tomography

      Maximum a posteriori estimator for high-contrast image composition of optical coherence tomography
      A quantitative signal amplitude estimator for optical coherence tomography (OCT) is presented. It is based on a statistical model of OCT signal and noise, using a Bayesian maximum a posteriori (MAP) estimation framework. Multiple OCT images are used for estimation, similar to the widely utilized intensity averaging method. The estimator is less biased especially at low-intensity regions, where intensity averaging approaches the noise power and hence is biased. The estimator ...
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    13. Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography

      Birefringence imaging of posterior eye by multi-functional Jones matrix optical coherence tomography
      A clinical grade prototype of posterior multifunctional Jones matrix optical coherence tomography (JM-OCT) is presented. This JM-OCT visualized depth-localized birefringence in addition to conventional cumulative phase retardation imaging through local Jones matrix analysis. In addition, it simultaneously provides a sensitivity enhanced scattering OCT, a quantitative polarization uniformity contrast, and OCT-based angiography. The probe beam is at 1- m wavelength band. The measurement speed and the depth-resolution were 100,000 A-lines ...
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    14. Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography

      Noninvasive vascular imaging of ruptured retinal arterial macroaneurysms by Doppler optical coherence tomography
      Background To describe Doppler optical coherence tomography (OCT) imaging of ruptured retinal arterial macroaneurysms (RAMs). Methods Four eyes of four patients with ruptured RAMs were prospectively studied. Vascular imaging was obtained using swept-source Doppler OCT, and compared with indocyanine green angiography images. Results En face projection of Doppler OCT images clearly showed RAMs at the corresponding locations of lesions in the indocyanine green angiography images. In Doppler OCT images, RAMs ...
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    15. Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography

      Noninvasive Vascular Imaging of Polypoidal Choroidal Vasculopathy by Doppler Optical Coherence Tomography
      Purpose. To noninvasively investigate the vascular architecture of polypoidal lesions in polypoidal choroidal vasculopathy (PCV) using Doppler optical coherence tomography (OCT), and to evaluate the clinical usefulness of Doppler OCT for the assessment of therapeutic effects in PCV. Methods. Fifteen eyes of 15 patients with treatment-nave PCV were prospectively studied. Vascular imaging was obtained using 1060-nm swept-source Doppler OCT, and compared with indocyanine green angiography (ICGA) images. The therapeutic effect ...
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  2. About Yoshiaki Yasuno

    Yoshiaki Yasuno

    Yoshiaki Yasuno is a Researcher in the Computational Optics Group in the Institute of Applied Physics, University of Tsukuba in Japan.