1. Yanmei Liang

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    1. Mentioned In 17 Articles

    2. High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging

      High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging
      Zebrafish are an important animal model, whose structure and function information can be used to study development, pathologic changes and genetic mutations. However, limited by the penetration depth, the available optical methods are difficult to image the whole-body zebrafish in juvenile and adult stages. Based on a home-made high-resolution polarization-sensitive optical coherence tomography (PS-OCT) system, we finished in vivo volumetric imaging for zebrafish, and various muscles can be clearly discerned ...
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    3. Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues

      Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues
      We report a multimodal optical system by combining OCT with autofluorescence imaging for identifying neck tissues, which can use the advantages of large field of view and high sensitivity for identifying parathyroid glands of fluorescence imaging, and high-resolution structural imaging of OCT to confirm them and identify lymph nodes and metastatic lymph nodes at the same time. It is proven that this multimodal optical system can be used to identify ...
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    4. Identification of oral cancer in OCT images based on an optical attenuation model

      Identification of oral cancer in OCT images based on an optical attenuation model
      Surgery is still the first choice to treat oral cancer, where it is important to detect surgical margins in order to reduce cancer recurrence and maintain oral-maxillofacial function simultaneously. As a non-invasive and in situ imaging technique, optical coherence tomography (OCT) can obtain images close to the resolution of histopathology, which makes it have great potential in intraoperative diagnosis. However, it is not enough to find surgical margins accurately just ...
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    5. Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging

      Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging
      Significance: Optical coherence tomography (OCT) has proven useful for detecting various oral maxillofacial abnormalities. To apply it to clinical applications including biopsy guidance and routine screening, a handheld imaging probe is indispensable. OCT probes reported for oral maxillofacial imaging were either based on a bulky galvanometric mirror pair (not compact or long enough) or a distal-end microelectromechanical systems (MEMS) scanner (raised safety concerns), or adapted from fiber-optic catheters (ill-suited for ...
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    6. Identification of atherosclerotic plaques in intravascular optical coherence tomography images based on textures and artificial neural network

      Identification of atherosclerotic plaques in intravascular optical coherence tomography images based on textures and artificial neural network
      Intravascular optical coherence tomography (IVOCT) is becoming an important choice for in vivo diagnosis of coronary artery diseases. The atherosclerotic disease can be detected from IVOCT images, but the segmentation of IVOCT images and identification of plaques are mainly performed manually. This process is laborious and time consuming and its accuracy relies on the expertise of the observer. To address these limitations, a semi-automated identification algorithm based on texture features ...
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    7. Robust, accurate depth-resolved attenuation characterization in optical coherence tomography

      Robust, accurate depth-resolved attenuation characterization in optical coherence tomography
      Depth-resolved optical attenuation coefficient is a valuable tissue parameter that complements the intensity-based structural information in optical coherent tomography (OCT) imaging. Herein we systematically analyzed the under- and over-estimation bias of existing depth-resolved methods when applied to real biological tissues, and then proposed a new algorithm that remedies these issues and accommodates general OCT data that contain incomplete decay and noise floor, thereby affording consistent estimation accuracy for practical biological ...
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    8. Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography

      Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography
      An approach to characterize laser-induced bulk damage in optical crystal materials was demonstrated. With a homemade swept-source optical coherence tomography (SS-OCT) system, we obtained three-dimensional images of the bulk damage produced by laser pulses with wavelength of 351 nm, pulse width of 5 ns, beam diameter of 5.5 mm and fluences from 4.56 J/cm 2 to 9.95 J/cm 2 in Potassium Dihydrogen Phosphate (KDP) crystal ...
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    9. Automatic identification of parathyroid in optical coherence tomography images

      Automatic identification of parathyroid in optical coherence tomography images
      Background and Objective The identification and preservation of parathyroid is a major problem in thyroid surgery. In order to solve this problem, optical coherence tomography was involved as a real-time, non-invasive high-resolution imaging technique. This study demonstrated an effective and fast method to distinguish parathyroid tissue from thyroid, lymph node, and adipose tissue in their ex vivo optical coherence tomography (OCT) images automatically. Methods OCT images were obtained from parathyroid ...
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    10. Optical clearing for luminal organ imaging with ultrahigh-resolution optical coherence tomography

      Optical clearing for luminal organ imaging with ultrahigh-resolution optical coherence tomography
      The imaging depth of optical coherence tomography (OCT) in highly scattering biological tissues (such as luminal organs) is limited, particularly for OCT operating at shorter wavelength regions (such as around 800nm). For the first time, the optical clearing effect of the mixture of liquid paraffin and glycerol on luminal organs was explored with ultrahigh-resolution spectral domain OCT at 800nm.Ex vivostudies were performed on pig esophagus and bronchus, and guinea ...
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    11. Study on application of optical clearing technique in skin diseases

      Study on application of optical clearing technique in skin diseases
      So far, the study of the optical clearing is almost always about healthy tissue. However, the ultimate goal is to detect diseases for clinical application. Optical clearing on diseased skins is explored. The effect is evaluated by applying a combined liquid paraffin and glycerol mixed solution on several kinds of diseased skins in vitro . Scanning experiments from optical coherence tomography show that it has different effects among fibroma, pigmented nevus ...
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    12. Analyses and calculations of noise in optical coherence tomography systems

      Significant progress has been made in the study of optical coherence tomography (OCT) - a non-invasive, high resolution, and in vivo diagnostic method for medical imaging applications. In this paper, the principles of noise analyses for OCT systems have been described. Comparisons are made of signal-to-noise ratios for both balanced and unbalanced detection schemes under the ideal no-stray light situation as well as the non-ideal situation where residual reflections and scatterings ...
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    13. Two-dimensional image sharpening in optical coherence tomography by deconvolution

      Point spread functions (PSF) of a given OCT system in both longitudinal and transversal directions often cause bluring in OCT images. A two-dimensional sharpening method is proposed to simultaneously deconvolve both the longitudinal and transversal PSFs. This is achieved through employing an artific ... [Proc. SPIE Int. Soc. Opt. Eng. 6826, 682608 (2008)] published Tue Jan 8, 2008.
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    14. 1-17 of 17
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  2. About Yanmei Liang

    Yanmei Liang

    Yanmei Liang is an associate professor ofNankai University,China. She received the Ph.D degree in optical engineering fromInstituteofModern OpticsatNankai University,Chinain 2003. Her research experience and interests are optical information processing and image processing. Her current research focus is the development of optical technology for medical application.