1. Yan Li

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    1. Mentioned In 62 Articles

    2. Oregon Health & Science University Receives NIH Grant for Optical Coherence Tomography Differential Diagnosis and Treatment of Irregular Corneas

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Oregon Health & Science University Receives NIH Grant for Optical Coherence Tomography Differential Diagnosis and Treatment of Irregular Corneas
      ...Coherence Tomography Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. Below is a summary of the proposed work.

      To see well, the cornea m...

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      Mentions: National Institutes of Health Oregon Health & Science University Yan Li

    3. Ultrahigh-sensitive optical coherence elastography

      Explore Nature Publishing Group
      Ultrahigh-sensitive optical coherence elastography
      The phase stability of an optical coherence elastography (OCE) system is the key determining factor for achieving a precise elasticity measurement, and it can be affected by the signal-to-noise ratio (SNR), timing jitters in the signal acquisition process, and fluctuations in the optical path difference (OPD) between the sample and reference arms. In this study, we developed an OCE system based on swept-source optical coherence tomography (SS-OCT) with a common-path ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    4. Bulk motion subtraction in optical coherence tomography angiography

      Explore uspto.gov Ophthalmology , Patents
      Bulk motion subtraction in optical coherence tomography angiography
      Described herein is an algorithm to remove decorrelation noise due to bulk motion in optical coherence tomography angiography (OCTA). OCTA B-frames are divided into segments within which the bulk motion velocity could be assumed constant. This velocity is recovered using linear regression of decorrelation versus the logarithm of reflectance in axial lines (A-lines) identified as bulk tissue by percentile analysis. The fitting parameters are used to calculate a reflectance-adjusted threshold ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    5. Optical Vaginal Biopsy Using Optical Coherence Tomography

      Explore LWW Online Gynecology
      Optical Vaginal Biopsy Using Optical Coherence Tomography
      Objective Optical coherence tomography is a noninvasive technology that visualizes tissue microstructure with high spatial resolution. We designed a novel vaginal system that demonstrates a clear distinction between vaginal tissues planes. In this study, we sought to compare vaginal tomographic images of premenopausal, perimenopausal, and postmenopausal women, demonstrate feasibility of tracking vaginal tissue changes after treatment with fractional-pixel CO 2 laser therapy, and obtain a histologic correlation of these findings ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    6. Early Diagnostic Value of Optical Coherence Tomography in The Clinical Prediction Model for Optic Nerve Injury in Saddle Space Occupying Patients

      Explore ScienceDirect Ophthalmology
      Early Diagnostic Value of Optical Coherence Tomography in The Clinical Prediction Model for Optic Nerve Injury in Saddle Space Occupying Patients
      In this study, 50 patients with anterior ischemic optic neuropathy due to saddle block were selected as the experimental group, and 50 healthy subjects were used as the control group to conduct a study. The best corrected visual acuity examination, optical coherence tomography and visual evoked potential examination were performed on the two groups. The results of the study showed that the majority of patients were middle-aged and older people ...
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      Mentions: Yan Li

    7. In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography

      Explore SAGE Journals Ophthalmology
      In vivo evaluation of posterior eye elasticity using shaker-based optical coherence elastography
      Age-related macular degeneration (AMD) is a progressive retinal disease and becomes the leading cause of blindness. It is well established that early detection is the key to preservation of functional vision. However, it is very difficult to diagnose AMD in very early stages, before structural changes are evident. Consequently, investigating the biomechanical properties of the retina maybe essential for understanding its physiological function. In this study, we present a shear ...
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      Mentions: Zhongping Chen University of Southern California UC Irvine

    8. Application of Corneal Optical Coherence Tomography Angiography for Assessment of Vessel Depth in Corneal Neovascularization

      Explore LWW Online Ophthalmology
      Application of Corneal Optical Coherence Tomography Angiography for Assessment of Vessel Depth in Corneal Neovascularization
      Purpose: To map and measure the depths of corneal neovascularization (NV) using 3-dimensional optical coherence tomography angiography (OCTA) at 2 different wavelengths. Methods: Corneal NV of varying severity, distribution, and underlying etiology was examined. Average NV depth and vessel density were measured using 840-nm spectral-domain OCTA and 1050-nm swept-source OCTA. The OCTA results were compared with clinical slit-lamp estimation of NV depth. Results: Twelve eyes with corneal NV from 12 ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto David Huang

    9. Cerebral edema detection in vivo after middle cerebral artery occlusion using swept-source optical coherence tomography

      Explore SPIE Digital Library Neurology
      Cerebral edema detection in vivo after middle cerebral artery occlusion using swept-source optical coherence tomography
      Cerebral edema is a severe complication of ischemic cerebrovascular disease, which can lead to microcirculation compression resulting in additional ischemic damage. Real-time and continuous in vivo imaging techniques for edema detection are of great significance to basic research on cerebral edema. We attempted to monitor the cerebral edema status in rats with middle cerebral artery occlusion (MCAO) over time, using a wide field-of-view swept-source optical coherence tomography (SS-OCT) system. Optical ...
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      Mentions: University of Michigan Yan Li

    10. OHSU Receives NIH Grant ffor Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      OHSU Receives NIH Grant ffor Optical Coherence Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas
      ...nce Tomography-Aided Differential Diagnosis and Treatment of Irregular Corneas. The principal investigator is Yan Li. The program began in 2018 and ends in 2023. Below is a summary of the proposed work.

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      Mentions: National Institutes of Health Oregon Health & Science University Yan Li

    11. Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging

      Explore OSA | OSA Publishing Gastroenterology
      Multimodal endoscopy for colorectal cancer detection by optical coherence tomography and near-infrared fluorescence imaging
      While colonoscopy is the gold standard for diagnosis and classification of colorectal cancer (CRC), its sensitivity and specificity are operator-dependent and are especially poor for small and flat lesions. Contemporary imaging modalities, such as optical coherence tomography (OCT) and near-infrared (NIR) fluorescence, have been investigated to visualize microvasculature and morphological changes for detecting early stage CRC in the gastrointestinal (GI) tract. In our study, we developed a multimodal endoscopic system ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    12. Visual Optics Postdoctoral/Research Fellow Opening at Oregon Health & Science University

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      Visual Optics Postdoctoral/Research Fellow Opening at Oregon Health & Science University
      ... independently and with team members. To apply, please contact Professors David Huang ( huangd@ohsu.edu ) and Yan Li ( liyan@ohsu.edu ). A postdoctoral research fellow position is available in the Center for Ophthalmic O...
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      Mentions: National Institutes of Health David Huang Oregon Health & Science University

    13. 1.7 micron optical coherence tomography for vaginal tissue characterization in vivo

      Explore Wiley Online Library Gynecology
      1.7 micron optical coherence tomography for vaginal tissue characterization in vivo
      Objectives Optical coherence tomography (OCT) can noninvasively visualize in vivo tissue microstructure with high spatial resolution that approaches the histologic level. Currently, OCT studies in gynecology are few and limited to a conventional 1.3m center wavelength swept light source which provides high spatial resolution but limited penetration depth. Here, we present a novel endoscopic OCT system with improved penetration depth and high resolution. Methods A novel endoscopic OCT system ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    14. Deep imaging in highly scattering media by combining reflection matrix measurement with Bessel-like beam based optical coherence tomography

      Explore aip.scitation.org
      Deep imaging in highly scattering media by combining reflection matrix measurement with Bessel-like beam based optical coherence tomography
      Multiple scattering in biomedical tissue limits the imaging depth within a range of 12mm for conventional optical imaging techniques. To extend the imaging depth into the scattering medium, a computational method based on the reflection matrix measurement has been developed to retrieve the singly back-scattered signal light from the dominant detrimental multiple-scattered background. After applying singular value decomposition on the measured matrix in the post-process, the target image underneath the ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    15. Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Multimodality endoscopic optical coherence tomography and fluorescence imaging technology for visualization of layered architecture and subsurface microvasculature
      Endoscopic imaging technologies, such as endoscopic optical coherence tomography (OCT) and near-infrared fluorescence, have been used to investigate vascular and morphological changes as hallmarks of early cancer in the gastrointestinal tract. Here we developed a high-speed multimodality endoscopic OCT and fluorescence imaging system. Using this system, the architectural morphology and vasculature of the rectum wall were obtained simultaneously from a Sprague Dawley rat in vivo . This multimodality imaging strategy in ...
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      Mentions: Zhongping Chen UC Irvine Yan Li

    16. Optical coherence tomography angiography of a pigmented Fuchs' adenoma (age-related hyperplasia of the nonpigmented ciliary body epithelium) masquerading as a ciliary body melanoma

      Explore ScienceDirect Ophthalmology
      Optical coherence tomography angiography of a pigmented Fuchs' adenoma (age-related hyperplasia of the nonpigmented ciliary body epithelium) masquerading as a ciliary body melanoma
      Purpose To report a case of age-related hypertrophy of the nonpigmented ciliary epithelium (ARH-NPCE) clinically resembling a ciliary body melanoma and report the optical coherence tomography angiography (OCTA) findings associated with this lesion. Observations A 51-year-old male was referred for evaluation of a deeply pigmented ciliary body mass with extension through the iris root. Iridocyclectomy was performed due to concern for ciliary body melanoma. Histopathologic analysis was instead consistent with ...
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      Mentions: David Huang Oregon Health & Science University Center for Ophthalmic Optics and Lasers
    17. 1-15 of 62 1 2 3 4 »
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  4. About Yan Li

    Yan Li

    Yan Li is with the Center for Opthalmic Optics and Lasers. Dr. Yan Li earned her PhD in Biomedical Engineering from Case Western Reserve University. She is currently a senior research associate in the Department of Ophthalmology, Keck School of Medicine of USC. She received her master’s degree in Biomedical Engineering at the Zhejiang University, China, in 2000. Her research interests include medical image processing, optical coherence tomography for imaging the corneal and anterior segment of the eye, planning refractive surgeries, and guiding the treatment of anterior eye diseases with optical coherence tomography.

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