1. Yalin Zheng

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    1. Mentioned In 15 Articles

    2. Differentiating Generic versus Branded Pharmaceutical Tablets Using Ultra-High-Resolution Optical Coherence Tomography

      Differentiating Generic versus Branded Pharmaceutical Tablets Using Ultra-High-Resolution Optical Coherence Tomography
      Optical coherence tomography (OCT) has recently been demonstrated as a powerful tool to image through pharmaceutical film coatings. Majority of the existing systems can, however, resolve film coatings for thickness greater than 10 m. Here we report on an ultra-high-resolution (UHR) OCT system, with 1 m axial and 1.6 m lateral resolutions, which can resolve thin coatings at approximately 4 m. We further demonstrate a novel application of the ...
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      Mentions: Yalin Zheng
    3. Sub-surface imaging of soiled cotton fabric using full-field optical coherence tomography

      Sub-surface imaging of soiled cotton fabric using full-field optical coherence tomography
      In the laundry industry, colorimetry is a common way to evaluate the stain removal efficiency of detergents and cleaning products. For ease of visualization, the soiling agent is treated with a dye before measurement. However, it effectively measures the dye removal rather than stain removal, and it cannot provide depth-resolved information of the sample. In this study, we show that full-field (FF) optical coherence tomography (OCT) technique is capable of ...
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      Mentions: Yalin Zheng
    4. Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures

      Line-Field Optical Coherence Tomography as a tool for In vitro characterization of corneal biomechanics under physiological pressures
      There has been a lot of interest in accurately characterising corneal biomechanical properties under intraocular pressure (IOP) to help better understand ocular pathologies that are associated with elevated IOP. This study investigates the novel use of Line-Field Optical Coherence Tomography (LF-OCT) as an elastographic tool for accurately measuring mechanical properties of porcine corneas based on volumetric deformation following varying IOPs. A custom-built LF-OCT was used to measure geometrical and corneal ...
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      Mentions: Yalin Zheng
    5. Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography

      Imaging of Corneal Neovascularization: Optical Coherence Tomography Angiography and Fluorescence Angiography
      Purpose : The purpose of this study was to compare optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) for the assessment of corneal neovascularization (CoNV). Methods : Patients with CoNV extending at least 3 mm into the cornea were included. All patients underwent corneal imaging at the same visit. Images were recorded using the AngioVue OCTA system (Optovue, Inc.) with the long corneal adaptor module (CAM-L). ICGA images were recorded ...
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    6. Deformation velocity imaging using optical coherence tomography and its applications to the cornea

      Deformation velocity imaging using optical coherence tomography and its applications to the cornea
      Optical coherence tomography (OCT) can monitor human donor corneas non-invasively during the de-swelling process following storage for corneal transplantation, but currently only resultant thickness as a function of time is extracted. To visualize and quantify the mechanism of de-swelling, we present a method exploiting the nanometer sensitivity of the Fourier phase in OCT data to image deformation velocities. The technique was demonstrated by non-invasively showing during de-swelling that osmotic flow ...
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      Mentions: Yalin Zheng
    7. Scan-Less Line Field Optical Coherence Tomography, with Automatic Image Segmentation, as a Measurement Tool for Automotive Coatings

      Scan-Less Line Field Optical Coherence Tomography, with Automatic Image Segmentation, as a Measurement Tool for Automotive Coatings
      The measurement of the thicknesses of layers is important for the quality assurance of industrial coating systems. Current measurement techniques only provide a limited amount of information. Here, we show that spectral domain Line Field (LF) Optical Coherence Tomography (OCT) is able to return to the user a cross sectional B-Scan image in a single shot with no mechanical moving parts. To reliably extract layer thicknesses from such images of ...
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      Mentions: Yalin Zheng
    8. High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography

      High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography
      We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 m in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an ...
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      Mentions: Yalin Zheng
    9. Reconstruction of 3D surface maps from anterior segment optical coherence tomography images using graph theory and genetic algorithms

      Reconstruction of 3D surface maps from anterior segment optical coherence tomography images using graph theory and genetic algorithms
      Automatic segmentation of anterior segment optical coherence tomography images provides an important tool to aid management of ocular diseases. Previous studies have mainly focused on 2D segmentation of these images. A novel technique capable of producing 3D maps of the anterior segment is presented here. This method uses graph theory and dynamic programming with shape constraint to segment the anterior and posterior surfaces in individual 2D images. Genetic algorithms are ...
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    10. Automated segmentation of the choroid in retinal optical coherence tomography images

      Automated segmentation of the choroid in retinal optical coherence tomography images
      The choroid is a tissue layer at the back of the eye, which can be imaged by optical coherence tomography (OCT). Choroidal thickness has been proven to be correlated to several ophthalmic diseases in several studies. In this paper we proposed a novel segmentation technique to address this challenge. This technique firstly automatically segments the inner boundary of the choroid using a two-stage fast active contour model. It secondly allows ...
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      Mentions: Yalin Zheng
    11. Volumetric image mining based on decomposition and graph analysis: An application to retinal optical coherence tomography

      Volumetric image mining based on decomposition and graph analysis: An application to retinal optical coherence tomography
      In this paper, we introduce a method for classifying volumetric images using a decomposition and graph analysis based method. Volume decomposition plays an important role in simplifying Three-Dimensional (3-D) volumes so as to enhance their analysis. Hierarchical decomposition techniques incrementally divide a given 3-D volume into sub-volumes according to some critical function and then (typically) represent the decomposition as a tree. The issue is the nature of the critical function ...
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      Mentions: Yalin Zheng
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  2. About Yalin Zheng

    Yalin Zheng

    Yalin Zheng is from the University of Liverpool, Department of Eye and Vision Science, Institute of Ageing and Chronic Disease, Department of Eye and Vision Science, United Kingdom