1. Yali Jia

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    1. Mentioned In 122 Articles

    2. Optical coherence tomography angiography of non-exudative choroidal neovascularization

      Optical coherence tomography angiography of non-exudative choroidal neovascularization
      Age-related macular degeneration (AMD) has been classified in two groups, neovascular and non-neovascular, which historically has been synonymous with exudative and non-exudative, respectively. Neovascular AMD occurs when pathologic blood vessels, choroidal neovascularization (CNV), arise from the choroid and extend above Bruchs membrane toward the outer retina. Often these vessels are exudative in nature, resulting in leakage of fluid, lipid exudate, or blood causing vision loss. The exudation from CNV allows ...
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    3. Choriocapillaris evaluation in choroideremia using optical coherence tomography angiography

      Choriocapillaris evaluation in choroideremia using optical coherence tomography angiography
      The choriocapillaris plays an important role in supporting the metabolic demands of the retina. Studies of the choriocapillaris in disease states with optical coherence tomography angiography (OCTA) have proven insightful. However, image artifacts complicate the identification and quantification of the choriocapillaris in degenerative diseases such as choroideremia. Here, we demonstrate a supervised machine learning approach to detect intact choriocapillaris based on training with results from an expert grader. We trained ...
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    4. Optical coherence tomographic angiography of choroidal neovascularization ill-defined with fluorescein angiography

      Optical coherence tomographic angiography of choroidal neovascularization ill-defined with fluorescein angiography
      Purpose To evaluate the morphological structure of ill-defined choroidal neovascularisation (CNV) with traditional fluorescein angiography (FA) compared with optical coherence tomographic angiography (OCTA). Methods A retrospective case series study of 11 eyes with ill-defined CNV on FA was performed. Eyes were scanned with commercially available spectral-domain optical coherence tomography (OCT) (70 000 A-scans/s). The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to distinguish blood flow from static tissue. En ...
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    5. Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors

      Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors
      Purpose To evaluate tumor vasculature with optical coherence tomography angiography (OCTA) in malignant iris melanomas and benign iris lesions. Design Cross-sectional observational clinical study. Participants Patients with iris lesions and healthy volunteers. Methods Eyes were imaged using OCTA systems operating at 1050- and 840-nm wavelengths. Three-dimensional OCTA scans were acquired. Iris melanoma patients treated with radiation therapy were imaged again after I-125 plaque brachytherapy at 6 and 18 months. Main ...
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    6. Visualization of 3 Distinct Retinal Plexuses by Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Visualization of 3 Distinct Retinal Plexuses by Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Importance Projection artifacts in optical coherence tomography angiography (OCTA) blur the retinal vascular plexuses together and limit visualization of the individual plexuses. Objective To describe projection-resolved (PR) OCTA in eyes with diabetic retinopathy (DR) and healthy eyes. Design, Setting, and Participants In this case-control study, patients with DR and healthy controls were enrolled in this observational study from January 26, 2015, to December 4, 2015, at a tertiary academic center ...
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    7. Automated Quantification of Nonperfusion in Three Retinal Plexuses Using Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Automated Quantification of Nonperfusion in Three Retinal Plexuses Using Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Purpose : The purpose of this study was to evaluate an automated algorithm for detecting avascular area (AA) in optical coherence tomography angiograms (OCTAs) separated into three individual plexuses using a projection-resolved technique. Methods : A 3 3 mm macular OCTA was obtained in 13 healthy and 13 mild nonproliferative diabetic retinopathy (NPDR) participants. A projection-resolved algorithm segmented OCTA into three vascular plexuses: superficial, intermediate, and deep. An automated algorithm detected AA ...
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    8. Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology

      Evaluation of artifact reduction in optical coherence tomography angiography with real-time tracking and motion correction technology
      Artifacts introduced by eye motion in optical coherence tomography angiography (OCTA) affect the interpretation of images and the quantification of parameters with clinical value. Eradication of such artifacts in OCTA remains a technical challenge. We developed an algorithm that recognizes five different types of motion artifacts and used it to evaluate the performance of three motion removal technologies. On en face maximum projection of flow images, the summed flow signal ...
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    9. Compensation for Reflectance Variation in Vessel Density Quantification by Optical Coherence Tomography Angiography

      Compensation for Reflectance Variation in Vessel Density Quantification by Optical Coherence Tomography Angiography
      Purpose : To compensate for reflectance variation when quantifying vessel density by optical coherence tomography angiography (OCTA). Methods : Healthy participants received 66-mm macular and 4.54.5-mm optic nerve head (ONH) angiography scans on a 70-kHz spectral-domain optical coherence tomography system. The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to compute the OCTA signal. Mean reflectance projection and maximum decorrelation projection were used to create en face OCT and OCTA images ...
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    10. Calibration of optical coherence tomography angiography with a microfluidic chip

      Calibration of optical coherence tomography angiography with a microfluidic chip
      A microfluidic chip with microchannels ranging from 8 to 96 m 96m was used to mimic blood vessels down to the capillary level. Blood flow within the microfluidic channels was analyzed with split-spectrum amplitude-decorrelation angiography (SSADA)-based optical coherence tomography (OCT) angiography. It was found that the SSADA decorrelation value was related to both blood flow speed and channel width. SSADA could differentiate nonflowing blood inside the microfluidic channels from ...
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    11. Evaluating Polypoidal Choroidal Vasculopathy With Optical Coherence Tomography Angiography

      Evaluating Polypoidal Choroidal Vasculopathy With Optical Coherence Tomography Angiography
      Purpose : We observed and analyzed the morphologic characteristics of polypoidal lesions and abnormal branching vascular network (BVN) in patients with polypoidal choroidal vasculopathy (PCV) by optical coherence tomography angiography (OCTA). Methods : A retrospective observational case series was done of patients with PCV. All patients were scanned with a 70-kHz spectral-domain OCT system using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm to distinguish blood flow from static tissue. The OCTA images of ...
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    12. Quantification of choroidal neovascularization vessel length using optical coherence tomography angiography

      Quantification of choroidal neovascularization vessel length using optical coherence tomography angiography
      Quantification of choroidal neovascularization (CNV) as visualized by optical coherence tomography angiography (OCTA) may have importance clinically when diagnosing or tracking disease. Here, we present an automated algorithm to quantify the vessel skeleton of CNV as vessel length. Initial segmentation of the CNV on en face angiograms was achieved using saliency-based detection and thresholding. A level set method was then used to refine vessel edges. Finally, a skeleton algorithm was ...
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    13. Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography

      Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography
      Purpose : To use multiplane en face Doppler optical coherence tomography (OCT) to measure the change in total retinal blood flow (TRBF) in response to hyperoxia. Methods : One eye of each healthy human participant ( n = 8) was scanned with a commercial high-speed (70-kHz) spectral OCT system. Three repeated scans were captured at baseline and after 10 minutes of oxygen (hyperoxia) by open nasal mask. The procedure was performed twice on day ...
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    14. Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study

      Relationship Between Retinal Perfusion and Retinal Thickness in Healthy Subjects: An Optical Coherence Tomography Angiography Study
      Purpose : To investigate the relationship between retinal perfusion and retinal thickness in the peripapillary and macular areas of healthy subjects. Methods : Using spectral-domain optic coherence tomography and split-spectrum amplitude decorrelation angiography (SSADA) algorithm, retinal perfusion and retinal thicknesses in the macular and peripapillary areas were measured in healthy volunteers, and correlations among these variables were analyzed. Results : Overall, 64 subjects (121 eyes) including 28 males and 36 females with a ...
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    15. Optical Coherence Tomography Angiography

      Optical Coherence Tomography Angiography
      Optical coherence tomography angiography (OCTA) is a noninvasive approach that can visualize blood vessels down to the capillary level. With the advent of high-speed OCT and efficient algorithms, practical OCTA of ocular circulation is now available to ophthalmologists. Clinical investigations that used OCTA have increased exponentially in the past few years. This review will cover the history of OCTA and survey its most important clinical applications. The salient problems in ...
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    16. 61-75 of 122 « 1 2 3 4 5 6 7 8 »
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