1. Yali Jia

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    1. Mentioned In 135 Articles

    2. Plexus-specific retinal capillary avascular area in exudative age-related macular degeneration with projection-resolved OCT angiography

      Explore BJO Online Ophthalmology
      Plexus-specific retinal capillary avascular area in exudative age-related macular degeneration with projection-resolved OCT angiography
      Objective To detect the plexus-specific retinal capillary avascular area in exudative age-related macular degeneration (EAMD) with projection-resolved optical coherence tomography angiography (PR-OCTA). Methods and analysis In this prospective cross-sectional single centre study, eyes with treatment-nave EAMD underwent macular 33mm OCTA with AngioVue system. OCTA scans were analysed and processed including three-dimensional projection artefact removal, retinal layer semi-automated segmentation and en face angiogram generation. Automated quantification of extrafoveal (excluding the central ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    3. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

      Explore OSA | OSA Publishing
      Split-spectrum amplitude-decorrelation angiography with optical coherence tomography
      Amplitude decorrelation measurement is sensitive to transverse flow and immune to phase noise in comparison to Doppler and other phase-based approaches. However, the high axial resolution of OCT makes it very sensitive to the pulsatile bulk motion noise in the axial direction. To overcome this limitation, we developed split-spectrum amplitude-decorrelation angiography (SSADA) to improve the signal-to-noise ratio (SNR) of flow detection. The full OCT spectrum was split into several narrower ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    4. Oregon Health & Science University Receives a NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Explore Optical Coherence Tomography News Ophthalmology
      Oregon Health & Science University Receives a NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
      ...tion-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy. The principal investigator is Yali Jia. Below is a summary of the proposed work. Our group has demonstrated that optical coherence tomograp...
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      Mentions: National Institutes of Health Oregon Health & Science University Yali Jia

    5. Sensorless adaptive-optics optical coherence tomographic angiography

      Explore OSA | OSA Publishing
      Sensorless adaptive-optics optical coherence tomographic angiography
      Optical coherence tomographic angiography (OCTA) can image the retinal blood flow but visualization of the capillary caliber is limited by the low lateral resolution. Adaptive optics (AO) can be used to compensate ocular aberrations when using high numerical aperture (NA), and thus improve image resolution. However, previously reported AO-OCTA instruments were large and complex, and have a small sub-millimeter field of view (FOV) that hinders the extraction of biomarkers with ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    6. Automated segmentation of retinal fluid volumes from structural and angiographic optical coherence tomography using deep learning

      Explore arxiv.org Ophthalmology
      Automated segmentation of retinal fluid volumes from structural and angiographic optical coherence tomography using deep learning
      Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 3-mm OCT scans were acquired on one eye by a 70-kHz OCT commercial AngioVue system (RTVue-XR; Optovue, Inc.) from 51 participants in a clinical diabetic retinopathy (DR) study (45 with retinal edema and 6 healthy controls). A CNN with U-Net-like architecture was ...
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      Mentions: Optovue Oregon Health & Science University Yali Jia

    7. Retinal capillary oximetry with visible light optical coherence tomography

      Explore pnas.org Ophthalmology
      Retinal capillary oximetry with visible light optical coherence tomography
      Assessing oxygen saturation (sO 2 ) remains challenging but is nonetheless necessary for understanding retinal metabolism. We and others previously achieved oximetry on major retinal vessels and measured the total retinal oxygen metabolic rate in rats using visible-light optical coherence tomography. Here we extend oximetry measurements to capillaries and investigate all three retinal vascular plexuses by amplifying and extracting the spectroscopic signal from each capillary segment under the guidance of optical ...
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      Mentions: Oregon Health & Science University Yali Jia

    8. Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography

      Explore OSA | OSA Publishing
      Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography
      Sensorless adaptive optics optical coherence tomography (AO-OCT) is a technology to image retinal tissue with high resolution by compensating ocular aberrations without wavefront sensors. In this Letter, a fast and robust hill-climbing algorithm is developed to optimize five Zernike modes in AO-OCT with a numerical aperture between that of conventional AO and commercial OCT systems. The merit function is generated in real time using graphics processing unit while axially tracking ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    9. Optical coherence tomography angiography avascular area association with one-year treatment requirement and disease progression in diabetic retinopathy

      Explore American Journal of Ophthalmology Ophthalmology
      Optical coherence tomography angiography avascular area association with one-year treatment requirement and disease progression in diabetic retinopathy
      Purpose To assess the association between optical coherence tomography angiography (OCTA) quantified avascular areas (AA) and diabetic retinopathy (DR) severity, progression and treatment requirement in the following year. Design Prospective cohort study. Methods We recruited diabetic patients from tertiary academic retina practice and obtained 3x3-mm macular OCTA scans with AngioVue system and standard 7-field color photographs at baseline and 1-year visit. A masked grader determined the DR severity from the ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    10. Systems and methods to remove shadowgraphic flow projections on OCT angiography

      Explore uspto.gov Ophthalmology , Patents
      Systems and methods to remove shadowgraphic flow projections on OCT angiography
      Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    11. Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography
      In vivo high-resolution images are the most direct way to understand retinal function and diseases. Here we report the use of visible-light optical coherence tomography with volumetric registration and averaging to achieve cellular-level retinal structural imaging in a rat eye, covering the entire depth of the retina. Vitreous fibers, nerve fiber bundles, and vasculature were clearly revealed, as well as at least three laminar sublayers in the inner plexiform layer ...
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      Mentions: Oregon Health & Science University Yali Jia

    12. Bulk motion subtraction in optical coherence tomography angiography

      Explore uspto.gov Ophthalmology , Patents
      Bulk motion subtraction in optical coherence tomography angiography
      Described herein is an algorithm to remove decorrelation noise due to bulk motion in optical coherence tomography angiography (OCTA). OCTA B-frames are divided into segments within which the bulk motion velocity could be assumed constant. This velocity is recovered using linear regression of decorrelation versus the logarithm of reflectance in axial lines (A-lines) identified as bulk tissue by percentile analysis. The fitting parameters are used to calculate a reflectance-adjusted threshold ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    13. Sectorwise Visual Field Simulation Using Optical Coherence Tomographic Angiography Nerve Fiber Layer Plexus Measurements in Glaucoma

      Explore ScienceDirect Ophthalmology
      Sectorwise Visual Field Simulation Using Optical Coherence Tomographic Angiography Nerve Fiber Layer Plexus Measurements in Glaucoma
      Purpose To simulate 24-2 visual field (VF) using optical coherence tomographic angiography (OCTA) for glaucoma evaluation. Design Cross-sectional study. Methods One eye each of 39 glaucoma and 31 age-matched normal participants was scanned using 4.5-mm OCTA scans centered on the disc. The peripapillary retinal nerve fiber layer plexus capillary density (NFLP_CD, %area) was measured. The NFLP_CD and 24-2 VF maps were divided into 8 corresponding sectors using an extension ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    14. Quantification of local circulation with OCT angiography

      Explore uspto.gov Ophthalmology , Patents
      Quantification of local circulation with OCT angiography
      Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    15. Measuring Glaucomatous Focal Perfusion Loss in the Peripapillary Retina using Optical Coherence Tomographic Angiography

      Explore Ophthalmology Ophthalmology
      Measuring Glaucomatous Focal Perfusion Loss in the Peripapillary Retina using Optical Coherence Tomographic Angiography
      Purpose To measure low perfusion areas (LPA) and focal perfusion loss (FPL) in the peripapillary retina using optical coherence tomographic angiography (OCTA) in glaucoma. Design Prospective observation study. Participants Forty-seven primary open angle glaucoma (POAG) patients and 36 normal subjects were analyzed. Methods One eye of each subject was scanned using AngioVue 4.5-mm OCTA scan centered on the disc. En face nerve fiber layer plexus angiogram was generated. Using ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    16. Longitudinal Detection of Radiation-Induced Peripapillary and Macular Retinal Capillary Ischemia Using Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Longitudinal Detection of Radiation-Induced Peripapillary and Macular Retinal Capillary Ischemia Using Optical Coherence Tomography Angiography
      Purpose To study longitudinal changes in retinal capillary circulation in eyes treated with iodine 125 (I-125) plaque brachytherapy for uveal melanoma using optical coherence tomography angiography (OCTA). Design Longitudinal prospective study of 21 subjects undergoing treatment for uveal melanoma with I-125 plaque brachytherapy. Eyes with melanoma were imaged with OCTA prior to treatment and at 12 month intervals until 2 years post-brachytherapy. Participants After IRB-approval, participants were enrolled prospectively from ...
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      Mentions: Optovue David Huang Oregon Health & Science University
    17. 1-15 of 135 1 2 3 4 5 6 7 8 9 »
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