1. Yali Jia

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    1. Mentioned In 114 Articles

    2. Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography

      Explore SPIE Digital Library Ophthalmology
      Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography
      Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the role of IOP in glaucoma progression, as well as retinal physiology in general, remains incompletely understood. We demonstrate the use of visible light optical coherence tomography to measure retinal responses to acute IOP elevation in Brown Norway rats. We monitored retinal responses in reflectivity, angiography, blood flow, oxygen saturation (sO2 ), and oxygen metabolism over a range of ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    3. High dynamic range optical coherence tomography angiography (HDR-OCTA)

      Explore OSA | OSA Publishing
      High dynamic range optical coherence tomography angiography (HDR-OCTA)
      The dynamic range of current optical coherence tomography (OCT) angiography (OCTA) images is limited by the fixed scanning intervals. High speed OCT devices introduce the possibility of extending the flow signal dynamic range. In this study, we created a novel scanning pattern for achieving high dynamic range (HDR)-OCTA with a superior scanning efficiency. We implemented a bidirectional, interleaved scanning pattern that is sensitive to different flow speeds by adjustable ...
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      Mentions: Oregon Health & Science University Yali Jia

    4. Systems and methods to compensate for reflectance variation in OCT angiography

      Explore uspto.gov Patents
      Systems and methods to compensate for reflectance variation in OCT angiography
      Methods and systems for improving quantification of OCT angiography data are disclosed. The disclosure specifically relates to methods for compensating for the effect of tissue reflectance to improve the accuracy and repeatability of OCT angiography measurements. These improvements are effected by deriving and then utilizing a dynamic thresholding approach to process decorrelation data to properly classify flow versus non-flow data in OCT angiograms. The disclosed methods overcome quantification errors associated ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    6. Correlation of Outer Retinal Degeneration and Choriocapillaris Loss in Stargardt Disease Using En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography

      Explore American Journal of Ophthalmology Ophthalmology
      Correlation of Outer Retinal Degeneration and Choriocapillaris Loss in Stargardt Disease Using En Face Optical Coherence Tomography and Optical Coherence Tomography Angiography
      Purpose This study measured and correlated degeneration of the junction between the inner and outer segments (IS/OS), the retinal pigment epithelium (RPE), and the choriocapillaris (CC) in Stargardt disease (STGD). Design Prospective cross-sectional study. Methods This study was conducted at the Casey Eye Institute. A total of 23 patients with STGD were enrolled and underwent optical coherence tomography angiography (OCTA). Scans were centered on the fovea. OCT slab projections ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    7. Signal strength reduction effects in optical coherence tomographic angiography

      Explore Ophthalmology Retina Ophthalmology
      Signal strength reduction effects in optical coherence tomographic angiography
      Objective To elucidate the relationship between vessel density (VD) measurements and signal strength in optical coherence tomography angiography (OCTA). Design Cross-sectional study. Subjects: Healthy volunteers. Methods OCTA images obtained from healthy volunteers were analyzed to demonstrate the relationship between signal strength index (SSI) and VD. Experiments were performed to determine the effects of signal strength reduction on VD measurements on the Optovue/AngioVue and Cirrus/AngioPlex OCTA systems. Signal strength ...
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      Mentions: Optovue David Huang Oregon Health & Science University

    8. Maximum value projection produces better en face OCT angiograms than mean value projection

      Explore OSA | OSA Publishing Ophthalmology
      Maximum value projection produces better en face OCT angiograms than mean value projection
      Optical coherence tomography angiography (OCTA) images rely on en face data projections for both qualitative and quantitative interpretation. Both maximum value and mean value projections are commonly used, and many researchers consider them essentially interchangeable approaches. On the contrary, we find that maximum value projection achieves a consistently higher signal-to-noise ratio and higher image contrast across multiple vascular layers, in both healthy eyes and for each disease examined.
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    9. OHSU Receives NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Angiography in Diabetic Retinopathy

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      OHSU Receives NIH Grant for Wide-Field and Projection-Resolved Optical Coherence Angiography in Diabetic Retinopathy
      ... and Projection-Resolved Optical Coherence Angiography in Diabetic Retinopathy. The principal investigator is Yali Jia. The program began in 2019 and ends in 2021. Below is a summary of the proposed work. Our group has ...
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      Mentions: National Institutes of Health Oregon Health & Science University Yali Jia

    10. Systems and methods for automated segmentation of retinal fluid in optical coherence tomography

      Explore uspto.gov Ophthalmology , Patents
      Systems and methods for automated segmentation of retinal fluid in optical coherence tomography
      Disclosed herein are methods and systems for the identification and characterization of fluid accumulation in the retina using OCT imaging. The disclosed methods and systems are directed to the automated segmentation of retinal fluid using 2D or 3D structural OCT scan images. Approaches for visualization and quantification of both intraretinal and subretinal fluid are presented. Methods are also disclosed for using OCT angiography data to improve the quality of retinal ...
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      Mentions: Oregon Health & Science University Yali Jia

    11. Detection of Non-exudative Choroidal Neovascularization and Progression to Exudative Choroidal Neovascularization Using Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Detection of Non-exudative Choroidal Neovascularization and Progression to Exudative Choroidal Neovascularization Using Optical Coherence Tomography Angiography
      Objective To detect non-exudative choroidal neovascularization (CNV) in age-related macular degeneration with optical coherence tomography angiography (OCTA) and determine risk of developing exudative CNV compared to eyes without non-exudative CNV. Design Prospective longitudinal observational study Participants Consecutive patients with drusen and pigmentary changes in the study eye and exudative neovascular AMD in the fellow eye. Methods Study participants underwent spectral domain OCTA (AngioVue, Optovue, Inc), clinical exam, and structural OCT ...
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      Mentions: Optovue David Huang Oregon Health & Science University

    12. Systems and methods to remove shadowgraphic flow projections in OCT angiography

      Explore uspto.gov Ophthalmology , Patents
      Systems and methods to remove shadowgraphic flow projections in OCT angiography
      Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    13. Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition

      Explore OSA | OSA Publishing Ophthalmology
      Real-time cross-sectional and en face OCT angiography guiding high-quality scan acquisition
      Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercially available OCTA systems are currently based on OCT signal quality alone, without knowledge of OCTA signal quality. This results in low yield rates for further quantification. In this Letter, we developed a novel OCTA platform based on ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    14. DETECTION OF CLINICALLY UNSUSPECTED RETINAL NEOVASCULARIZATION WITH WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      DETECTION OF CLINICALLY UNSUSPECTED RETINAL NEOVASCULARIZATION WITH WIDE-FIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To evaluate wide-field optical coherence tomography angiography (OCTA) for detection of clinically unsuspected neovascularization (NV) in diabetic retinopathy (DR). Methods: This prospective observational single-center study included adult patients with a clinical diagnosis of nonproliferative DR. Participants underwent a clinical examination, standard 7-field color photography, and OCTA with commercial and prototype swept-source devices. The wide-field OCTA was achieved by montaging five 6 10-mm scans from a prototype device into a ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    15. Automated detection of shadow artifacts in optical coherence tomography angiography

      Explore OSA | OSA Publishing Ophthalmology
      Automated detection of shadow artifacts in optical coherence tomography angiography
      Frequently, when imaging retinal vasculature with optical coherence tomography angiography (OCTA) in diseased eyes, there are unavoidable obstacles to the propagation of light such as vitreous floaters or the pupil boundary. These obstacles can block the optical coherence tomography (OCT) beam and impede the visualization of the underlying retinal microcirculation. Detecting these shadow artifacts is especially important in the quantification of metrics that assess retinal disease progression because they might ...
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      Mentions: David Huang Oregon Health & Science University Yali Jia

    16. Automated phase unwrapping in Doppler optical coherence tomography

      Explore SPIE Digital Library
      Automated phase unwrapping in Doppler optical coherence tomography
      Phase wrapping is a crucial issue in Doppler optical coherence tomography (OCT) and restricts its automatic implementation for clinical applications that quantify total retinal blood flow. We propose an automated phase-unwrapping technique that takes advantage of the parabolic profile of blood flow velocity in vessels. Instead of inspecting the phase shift manually, the algorithm calculates the gradient magnitude of the phase shift on the cross-sectional image and automatically detects the ...
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      Mentions: Oregon Health & Science University Yali Jia
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