Articles that mention Yali Jia -Optical Coherence Tomography News

Yali Jia

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1. Mentioned In 130 Articles
2. Retinal capillary oximetry with visible light optical coherence tomography
  
  Explore pnas.org May 12 2020 Ophthalmology
  
  Assessing oxygen saturation (sO 2 ) remains challenging but is nonetheless necessary for understanding retinal metabolism. We and others previously achieved oximetry on major retinal vessels and measured the total retinal oxygen metabolic rate in rats using visible-light optical coherence tomography. Here we extend oximetry measurements to capillaries and investigate all three retinal vascular plexuses by amplifying and extracting the spectroscopic signal from each capillary segment under the guidance of optical ...
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  Mentions: Oregon Health & Science University Yali Jia
3. Depth-resolved optimization of a real-time sensorless adaptive optics optical coherence tomography
  
  Explore OSA | OSA Publishing May 2 2020
  
  Sensorless adaptive optics optical coherence tomography (AO-OCT) is a technology to image retinal tissue with high resolution by compensating ocular aberrations without wavefront sensors. In this Letter, a fast and robust hill-climbing algorithm is developed to optimize five Zernike modes in AO-OCT with a numerical aperture between that of conventional AO and commercial OCT systems. The merit function is generated in real time using graphics processing unit while axially tracking ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
4. Optical coherence tomography angiography avascular area association with one-year treatment requirement and disease progression in diabetic retinopathy
  
  Explore American Journal of Ophthalmology Apr 29 2020 Ophthalmology
  
  Purpose To assess the association between optical coherence tomography angiography (OCTA) quantified avascular areas (AA) and diabetic retinopathy (DR) severity, progression and treatment requirement in the following year. Design Prospective cohort study. Methods We recruited diabetic patients from tertiary academic retina practice and obtained 3x3-mm macular OCTA scans with AngioVue system and standard 7-field color photographs at baseline and 1-year visit. A masked grader determined the DR severity from the ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
5. Systems and methods to remove shadowgraphic flow projections on OCT angiography
  
  Explore uspto.gov Apr 28 2020 Ophthalmology , Patents
  
  Methods and systems for suppressing shadowgraphic flow projection artifacts in OCT angiography images of a sample are disclosed. In one example approach, normalized OCT angiography data is analyzed at the level of individual A-scans to classify signals as either flow or projection artifact. This classification information is then used to suppress projection artifacts in the three dimensional OCT angiography dataset.
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  Mentions: David Huang Oregon Health & Science University Yali Jia
6. Imaging retinal structures at cellular-level resolution by visible-light optical coherence tomography
  
  Explore OSA | OSA Publishing Apr 3 2020 Ophthalmology
  
  In vivo high-resolution images are the most direct way to understand retinal function and diseases. Here we report the use of visible-light optical coherence tomography with volumetric registration and averaging to achieve cellular-level retinal structural imaging in a rat eye, covering the entire depth of the retina. Vitreous fibers, nerve fiber bundles, and vasculature were clearly revealed, as well as at least three laminar sublayers in the inner plexiform layer ...
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  Mentions: Oregon Health & Science University Yali Jia
7. Bulk motion subtraction in optical coherence tomography angiography
  
  Explore uspto.gov Mar 17 2020 Ophthalmology , Patents
  
  Described herein is an algorithm to remove decorrelation noise due to bulk motion in optical coherence tomography angiography (OCTA). OCTA B-frames are divided into segments within which the bulk motion velocity could be assumed constant. This velocity is recovered using linear regression of decorrelation versus the logarithm of reflectance in axial lines (A-lines) identified as bulk tissue by percentile analysis. The fitting parameters are used to calculate a reflectance-adjusted threshold ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
8. Sectorwise Visual Field Simulation Using Optical Coherence Tomographic Angiography Nerve Fiber Layer Plexus Measurements in Glaucoma
  
  Explore ScienceDirect Nov 29 2019 Ophthalmology
  
  Purpose To simulate 24-2 visual field (VF) using optical coherence tomographic angiography (OCTA) for glaucoma evaluation. Design Cross-sectional study. Methods One eye each of 39 glaucoma and 31 age-matched normal participants was scanned using 4.5-mm OCTA scans centered on the disc. The peripapillary retinal nerve fiber layer plexus capillary density (NFLP_CD, %area) was measured. The NFLP_CD and 24-2 VF maps were divided into 8 corresponding sectors using an extension ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
9. Quantification of local circulation with OCT angiography
  
  Explore uspto.gov Nov 26 2019 Ophthalmology , Patents
  
  Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
10. Measuring Glaucomatous Focal Perfusion Loss in the Peripapillary Retina using Optical Coherence Tomographic Angiography
  
  Explore Ophthalmology Nov 12 2019 Ophthalmology
  
  Purpose To measure low perfusion areas (LPA) and focal perfusion loss (FPL) in the peripapillary retina using optical coherence tomographic angiography (OCTA) in glaucoma. Design Prospective observation study. Participants Forty-seven primary open angle glaucoma (POAG) patients and 36 normal subjects were analyzed. Methods One eye of each subject was scanned using AngioVue 4.5-mm OCTA scan centered on the disc. En face nerve fiber layer plexus angiogram was generated. Using ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
11. Longitudinal Detection of Radiation-Induced Peripapillary and Macular Retinal Capillary Ischemia Using Optical Coherence Tomography Angiography
  
  Explore ScienceDirect Oct 15 2019 Ophthalmology
  
  Purpose To study longitudinal changes in retinal capillary circulation in eyes treated with iodine 125 (I-125) plaque brachytherapy for uveal melanoma using optical coherence tomography angiography (OCTA). Design Longitudinal prospective study of 21 subjects undergoing treatment for uveal melanoma with I-125 plaque brachytherapy. Eyes with melanoma were imaged with OCTA prior to treatment and at 12 month intervals until 2 years post-brachytherapy. Participants After IRB-approval, participants were enrolled prospectively from ...
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  Mentions: Optovue David Huang Oregon Health & Science University
12. Automated quantification of nonperfusion in the retina using optical coherence tomography angiography
  
  Explore uspto.gov Oct 1 2019 Ophthalmology , Patents
  
  Disclosed are methods and systems for measuring areas of nonperfusion in the retina using OCT imaging. The disclosed methods and systems allow for the automated segmentation and quantification of avascular areas of the retina utilizing information obtained from both structural OCT and OCT angiography (OCTA) data. The disclosed methods include filtering approaches which enhance vessel structure while suppressing noise, dynamic thresholding approaches to mitigate the detrimental effects of within-scan variability ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
13. Detecting and measuring areas of choriocapillaris low perfusion in intermediate, non-neovascular age-related macular degeneration
  
  Explore SPIE Digital Library Sep 17 2019 Ophthalmology
  
  Age-related macular degeneration (AMD) is a vision-threatening disease that affects the outer retina and choroid of elderly adults. Because photoreceptors are found in the outer retina and rely primarily on the trophic support of the underlying choriocapillaris, imaging of flow or lack thereof in choriocapillaris by optical coherence tomography angiography (OCTA) has great clinical potential in AMD assessment. We introduce a metric using OCTA, named focal perfusion loss (FPL) to ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
14. Detection of reduced retinal vessel density in eyes with geographic atrophy secondary to age-related macular degeneration using projection-resolved optical coherence tomography angiography
  
  Explore American Journal of Ophthalmology Sep 14 2019 Ophthalmology
  
  Purpose To compare retinal vessel density in eyes with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) to age-matched healthy eyes using projection-resolved optical coherence tomography angiography (PR-OCTA). Design Prospective cross-sectional study. Methods Study participants underwent macular 33-mm OCTA scans with spectral domain OCTA. Reflectance-compensated retinal vessel densities were calculated on projection-resolved superficial vascular complex (SVC), intermediate capillary plexus (ICP), and deep capillary plexus (DCP). Quantitative analysis using normalized ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
15. Automated segmentation of peripapillary retinal boundaries in OCT combining a convolutional neural network and a multi-weights graph search
  
  Explore OSA | OSA Publishing Aug 29 2019
  
  Quantitative analysis of the peripapillary retinal layers and capillary plexuses from optical coherence tomography (OCT) and OCT angiography images depend on two segmentation tasks delineating the boundary of the optic disc and delineating the boundaries between retinal layers. Here, we present a method combining a neural network and graph search to perform these two tasks. A comparison of this novel methods segmentation of the disc boundary showed good agreement with ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
16. Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography
  
  Explore SPIE Digital Library Jul 18 2019 Ophthalmology
  
  Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the role of IOP in glaucoma progression, as well as retinal physiology in general, remains incompletely understood. We demonstrate the use of visible light optical coherence tomography to measure retinal responses to acute IOP elevation in Brown Norway rats. We monitored retinal responses in reflectivity, angiography, blood flow, oxygen saturation (sO2 ), and oxygen metabolism over a range of ...
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  Mentions: David Huang Oregon Health & Science University Yali Jia
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