1. Wolfgang Drexler

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    1. Mentioned In 119 Articles

    2. Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees.

      Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT  on December 15th in Rome Italy which Already has over 1,000 Attendees.
      ...Eric Souied, Richard Spaide, Giovanni Staurenghi, Nadia Waheed. Quan Dong Nguyen, SriniVas Sadda, Yves Cohen, Wolfgang Drexler, Joseph Carroll, and Ursula Schmidt Erfurth. The growing number of attendees (from 450 to 145...
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    3. Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography

      Mapping Retinal and Choroidal Thickness in Unilateral Nongranulomatous Acute Anterior Uveitis Using Three-Dimensional 1060-nm Optical Coherence Tomography
      Purpose : To analyze retinal thickness (RT) and choroidal thickness (ChT) changes in patients with unilateral nongranulomatous acute anterior uveitis (AAU) using three-dimensional (3D) 1060-nm optical coherence tomography (OCT). Methods : Retinal and choroidal thickness maps were statistically analyzed for 24 patients with newly diagnosed unilateral AAU before therapy. A total of 17 patients were followed until resolution of inflammatory activity (twice in the first week, then weekly). Resolution occurred in all ...
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    4. Mapping diurnal changes in choroidal, Haller’s and Sattler’s layer thickness using 3-dimensional 1060-nm optical coherence tomography

      Mapping diurnal changes in choroidal, Haller’s and Sattler’s layer thickness using 3-dimensional 1060-nm optical coherence tomography
      Purpose To test the significance of diurnal changes in choroidal, Hallers and Sattlers layer thickness in healthy subjects using spatial analysis of three-dimensional (3D) 1060-nm optical coherence tomography (OCT) scans. Methods Automatically generated choroidal, Hallers and Sattlers layer thickness maps were statistically analyzed for 19 healthy subjects at two time points (8 a.m. and 6 p.m.) that represent the currently proposed ChT peak and nadir. All subjects were ...
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    5. Introduction to the feature issue on the 25 year anniversary of optical coherence tomography

      Introduction to the feature issue on the 25 year anniversary of optical coherence tomography
      This feature issue commemorates the approximately 25 year history of Optical Coherence Tomography (OCT), one of the most successful biophotonic technologies. While OCT has technological origins traceable to ultrafast laser development and fiber optic system test instrumentation of the 1980s, innovations in low coherence interferometry for optical ranging and imaging for biomedical applications in the U.S., Europe and Japan by the early 1990s led to coinage of the now ...
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    6. Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics

      Visualization of micro-capillaries using optical coherence tomography angiography with and without adaptive optics
      The purpose of this work is to investigate the benefits of adaptive optics (AO) technology for optical coherence tomography angiography (OCTA). OCTA has shown great potential in non-invasively enhancing the contrast of vessels and small capillaries. Especially the capability of the technique to visualize capillaries with a lateral extension that is below the transverse resolution of the system opens unique opportunities in diagnosing retinal vascular diseases. However, there are some ...
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    7. OCT - catching macular degeneration before vision loss

      OCT - catching macular degeneration before vision loss
      Growing old leads to a growing number of health problems, including those that challenge our ability to see. Age-related macular degeneration (AMD) is a disease that -- until recently -- robbed the elderly of the ability to read, drive and see the faces of their loved ones. Thanks to the invention of OCT, doctors can catch the disease before vision is lost. And with the aid of new drugs, AMD can be ...
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    8. Comprehensive vascular imaging using optical coherence tomography-based angiography and photoacoustic tomography

      Comprehensive vascular imaging using optical coherence tomography-based angiography and photoacoustic tomography
      Studies have proven the relationship between cutaneous vasculature abnormalities and dermatological disorders, but to image vasculature noninvasively in vivo , advanced optical imaging techniques are required. In this study, we imaged a palm of a healthy volunteer and three subjects with cutaneous abnormalities with photoacoustic tomography (PAT) and optical coherence tomography with angiography extension (OCTA). Capillaries in the papillary dermis that are too small to be discerned with PAT are visualized ...
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    9. Combined multi-modal photoacoustic tomography, optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging

      Combined multi-modal photoacoustic tomography, optical coherence tomography (OCT) and OCT angiography system with an articulated probe for in vivo human skin structure and vasculature imaging
      ...1479–1489 (2006). [Crossref] [PubMed] A. Alex, B. Považay, B. Hofer, S. Popov, C. Glittenberg, S. Binder, and W. Drexler, “Multispectral in vivo three-dimensional optical coherence tomography of human skin,” J. Biomed. O...
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    10. Key Developments for Partial Coherence Biometry and Optical Coherence Tomography in the Human Eye Made in Vienna

      Key Developments for Partial Coherence Biometry and Optical Coherence Tomography in the Human Eye Made in Vienna
      Purpose : To describe key developments of optical biometry and optical coherence tomography (OCT) for ophthalmic applications made by one of the pioneering research groups. Methods : Partial coherence interferometry (PCI) as the basic ranging technology for modern optical biometry and for OCT was introduced for biomedical applications in the 1980s. Later, Fourier domain (FD) OCT was introduced and demonstrated to provide superior sensitivity as compared to time domain OCT. Further developments ...
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    11. Multi-modal adaptive optics system including fundus photography and optical coherence tomography for the clinical setting

      Multi-modal adaptive optics system including fundus photography and optical coherence tomography for the clinical setting
      We present a new compact multi-modal imaging prototype that combines an adaptive optics (AO) fundus camera with AO-optical coherence tomography (OCT) in a single instrument. The prototype allows acquiring AO fundus images with a field of view of 4x4 and with a frame rate of 10fps. The exposure time of a single image is 10 ms. The short exposure time results in nearly motion artifact-free high resolution images of the ...
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    12. Line-field parallel swept source interferometric imaging at up to 1  MHz

      Line-field parallel swept source interferometric imaging at up to 1  MHz
      We present a novel medical imaging modality based on optical coherence tomography (OCT) that enables in vivo 3D tomography at acquisition rates up to 1 MHz. Line field parallel swept source interferometric imaging (LPSI) combines line-field swept source OCT with modulation of the interferometric signal in spatial direction for full range imaging. This method enables high speed imaging with cost-effective and commercially available technology. We explain the realization of the ...
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    13. In vivo dual-modality photoacoustic and optical coherence tomography imaging of human dermatological pathologies

      In vivo dual-modality photoacoustic and optical coherence tomography imaging of human dermatological pathologies
      ...ed] A. Alex, J. Weingast, M. Weinigel, M. Kellner-Höfer, R. Nemecek, M. Binder, H. Pehamberger, K. König, and W. Drexler, “Three-dimensional multiphoton/optical coherence tomography for diagnostic applications in dermato...
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    14. 1-15 of 119 1 2 3 4 5 6 7 8 »
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  2. About Wolfgang Drexler

    Wolfgang Drexler

    Wolfgang Drexler was a Full Professor of Biomedical Imaging at the School of Optometry and Vision Sciences at Cardiff University, Wales, UK from 2006 to 2009. Since October 2009 he is a Full Professor of Medical Physics and the Head of the Center for Medical Physics and Biomedical Engineering at the Medical University of Vienna, Austria, Honorary Distinguished Professor at Cardiff University and is also Director of the Christian Doppler Laboratory. He is a member of the Austrian Academy of Science and has published more than 150 publications (including Nature Medicine and PNAS).

  3. Quotes

    1. State-of-the-art OCT technology has its limitations: it is bulky, the size of a desk top and quite expensive, costing anything in the region of €100, 000 per unit. It can detect abnormalities but at the present moment, compact, cost effective versions that can be used outside of hospitals and in private practice in a hand held mode do not exist...The core component of our OCTChip project targets the size of a 1 cent coin. It will reduce costs and is maintenance free. Hence retinal diseases like Diabetic Retinopathy and Glaucoma as well as other retina diseases that are worldwide leading causes for blindness might be diagnosed via screening with this cost-effective compact point-of-care version of OCT...OCTChip fosters wide spread use to visualise and quantify the retina in more definition, so we can diagnose diseases better, quicker, and cheaper.
      In Coin-Sized Scanner to Target Blindness
    2. Miniaturization of OCT-based imaging technology on integrated photonics enables a novel, unique generation of not only cost-effective, but also compact, robust and nearly maintenance-free handheld OCT systems...The partners of the BiopsyPen Project have exquisite complementary expertise to accomplish a significant step towards this ambitious goal.”
      In MedLumics Announces “BiopsyPen Project” with €3.6M EU in Funding; Initiative Aimed at New Clinical Applications for Optical Coherence Tomography
    3. Swept-source technology from Insight has the potential to revolutionize OCT in the future, especially regarding ease of use, flexibility, and unique OCT performance.
      In Akinetic all-semiconductor swept lasers boost OCT image quality
    4. Lasers and light-­‐based methods have long promised to deliver benefits to clinicians through faster, more accurate, more sensitive, and more cost-­‐effective diagnosis of cancer and other important diseases, but so far most optical diagnostic instruments are expensive, complex and have limited performance. A key reason for this is that the lasers and light sources they use, are adapted from other industrial and scientific applications, and have not been optimized for these new clinical uses. Now in FAMOS, we will develop and demonstrate the next generation of light sources to produce step changes in cost/performance that will trigger development of a whole new world of non-­‐invasive clinical diagnostic tools.
      In European Commission backs biophotonics ‘FAMOS’ consortium with €10.1M for project to develop new lasers for earlier, better diagnosis of major diseases
    5. We've passed acceptance and we're between elation and state of the art...I personally think that OCT will never replace any gold standard like histology or established imaging modalities, but it will be very important at generating information in the future...It provides you with more information for earlier diagnosis.
      In Optical coherence tomography: cellular and functional retinal imaging