1. Wenzhou Medical College

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    1. Mentioned In 122 Articles

    2. Optical coherence tomography angiography of the macular microcirculation in acute primary angle closure treated with phacoemulsification

      Optical coherence tomography angiography of the macular microcirculation in acute primary angle closure treated with phacoemulsification
      Purpose: To measure the changes of macular microcirculation in cases with unilateral acute primary angle closure (APAC) who were managed by phacoemulsification. Methods: Patients with unilateral APAC and managed by phacoemulsification were enrolled. The contralateral unaffected eyes were served as fellow group, and normal individuals were recruited as control group. Optical coherence tomography angiography (OCT-A) was performed to analyze the macular whole image vessel density (wiVD) and parafoveal vessel density ...
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    3. The Relationship Between Age and the Morphology of the Crystalline Lens, Ciliary Muscle, Trabecular Meshwork, and Schlemm's Canal: An in vivo Swept-Source Optical Coherence Tomography Study

      The Relationship Between Age and the Morphology of the Crystalline Lens, Ciliary Muscle, Trabecular Meshwork, and Schlemm's Canal: An in vivo Swept-Source Optical Coherence Tomography Study
      Purpose: To evaluate the effects of age on the morphologies of the crystalline lens, ciliary muscle (CM), Schlemm's canal (SC), and trabecular meshwork (TM) using swept-source optical coherence tomography (SS-OCT). Methods: Images of the crystalline lens and iridocorneal angle were obtained in healthy participants' eyes using SS-OCT. Morphological parameters of the crystalline lens, CM, and TM/SC were measured, and the relationship between these parameters and age was evaluated ...
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    4. Automatic Screening and Identifying Myopic Maculopathy on Optical Coherence Tomography Images Using Deep Learning

      Automatic Screening and Identifying Myopic Maculopathy on Optical Coherence Tomography Images Using Deep Learning
      Purpose: The purpose of this study was to engineer deep learning (DL) models that can identify myopic maculopathy in patients with high myopia based on optical coherence tomography (OCT) images. Methods: An artificial intelligence (AI) system was developed using 2342 qualified OCT macular images from 1041 patients with pathologic myopia admitted to the Affiliated Eye Hospital of Wenzhou Medical University (WMU). We adopted an ResNeSt101 architecture to train five independent ...
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    5. EE-Net: An edge-enhanced deep learning network for jointly identifying corneal micro-layers from optical coherence tomography

      EE-Net: An edge-enhanced deep learning network for jointly identifying corneal micro-layers from optical coherence tomography
      Accurate delineation of the corneal micro-layers depicted on optical coherence tomography (OCT) plays an important role in computerized detection and diagnosis of various corneal diseases ( e.g. , keratoconus and dry eye). In this study, we present a novel edge-enhanced convolutional neural network termed EE-Net to automatically delineate three corneal micro-layers from OCT images at the same time, including the epithelium layer, Bowmans layer, and stroma layer. We innovatively introduced a ...
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    6. Automated delineation of corneal layers on OCT images using a boundary-guided CNN

      Automated delineation of corneal layers on OCT images using a boundary-guided CNN
      Accurate segmentation of corneal layers depicted on optical coherence tomography (OCT) images is very helpful for quantitatively assessing and diagnosing corneal diseases ( e.g ., keratoconus and dry eye). In this study, we presented a novel boundary-guided convolutional neural network (CNN) architecture (BG-CNN) to simultaneously extract different corneal layers and delineate their boundaries. The developed BG-CNN architecture used three convolutional blocks to construct two network modules on the basis of the ...
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    7. Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia

      Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia
      Background/aims: Pathological myopia (PM) is a leading cause of blindness worldwide. We aimed to evaluate microvascular and chorioretinal changes in different stages of myopia with wide-field (WF) swept-source (SS) optical coherence tomography angiography (OCTA). Methods: This prospective cross-sectional observational study included 186 eyes of 122 patients who had undergone imaging between November 2018 and October 2020. Vessel density (VD) and vessel skeletonised density (VSD) of superficial capillary plexus, deep ...
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    8. Retinal Vascular Changes during the Menstrual Cycle Detected with Optical Coherence Tomography Angiography

      Retinal Vascular Changes during the Menstrual Cycle Detected with Optical Coherence Tomography Angiography
      Purpose. To evaluate the effects of the menstrual cycle on the retinal vascular status of healthy women by optical coherence tomography angiography (OCTA). Materials and Methods. Healthy women with regular natural menstrual cycles of 28 to 30 days were recruited for this prospective study. The womens retinal vascular status was measured by OCTA at 3 time points: the early follicular, ovulatory, and midluteal phases of the menstrual cycle. The main ...
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    9. Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography

      Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography
      Purpose . To measure the macular retinal vessel density (VD) and peripapillary retinal nerve fiber layer (RNFL) in primary angle-closure suspects (PACS) by Angio-OCT to be compared with normal subjects. Methods . Primary angle-closure suspect patients and normal subjects were enrolled in this study. The demographic and clinical characteristics of all subjects, such as RNFL thickness, retinal vessel density, and ocular perfusion pressure, were compared. Results . No significant difference was found in ...
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    10. Macular perfusion density evaluation in constant and intermittent exotropia by means of optical coherence tomography angiography

      Macular perfusion density evaluation in constant and intermittent exotropia by means of optical coherence tomography angiography
      Background: To quantify and compare retinal microvascular features using optical coherence tomography angiography (OCTA) in constant (XT) and intermittent exotropia (IXT). Methods: An observational cross-sectional study was conducted from September 2020 to November 2020 at the Affiliated Eye Hospital of Wenzhou Medical University. OCTA examination was performed to evaluate the macular perfusion density of the deep capillary plexus (DCP), superficial capillary plexus (SCP), and foveal avascular zone (FAZ) parameters in ...
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    11. Effect of Age and Cycloplegia on the Morphology of the Human Crystalline Lens: a Swept-source Optical Coherence Tomography Study

      Effect of Age and Cycloplegia on the Morphology of the Human Crystalline Lens: a Swept-source Optical Coherence Tomography Study
      Purpose: To evaluate the effect of age and cycloplegia on the morphology of crystalline lens using a swept-source optical coherence tomography (SS-OCT) system. Setting: hospital. Design: Prospective cross-sectional study. Methods: Seventy six individuals (age range, 18 to 86 years) were recruited. The parameters including anterior chamber depth (ACD), the radii of curvature of the anterior and posterior surface of crystalline lens (ALR and PLR), lens thickness (LT), lens equatorial diameter ...
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    12. Spectral-Domain Optical Coherence Tomography Imaging of the Typical cystoid degeneration

      Spectral-Domain Optical Coherence Tomography Imaging of the Typical cystoid degeneration
      Purpose: To describe the spectral-domain optical coherence tomography (SD-OCT) features of typical cystoid degeneration. Methods: This was a retrospective study of 11 eyes with typical cystoid degeneration (TCD). All patients had a complete ocular examination, ultra-widefield (UWF) pseudocolor fundus photography and SD-OCT with a 55 wide-field lens. We analyzed the cross-sectional structural information of SD-OCT imaging with TCD. Results: On SD-OCT, the TCD regions exhibited rolling hills patterns with irregularly ...
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    13. Identification of peripheral anterior synechia with anterior segment optical coherence tomography

      Identification of peripheral anterior synechia with anterior segment optical coherence tomography
      Purpose: To generate a model that evaluates the presence and extent of peripheral anterior synechia (PAS) based on anterior segment optical coherence tomography (AS-OCT). Methods: The extent of PAS involvement in the eyes of patients with angle closure was assessed by indentation gonioscopy, and the part of non-PAS and PAS were assigned into two groups (NPAS and PAS). Anterior chamber angles were then imaged by AS-OCT with light-emitting diode (LED ...
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    14. Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography

      Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography
      Purpose: To investigate the changes and evaluate the diagnosis value of circumpapillary vessel density (VD) in cases of acute primary angle closure (APAC). Design: Case-control study. Methods: APAC patients with a history of unilateral acute attack were enrolled. The eyes with acute episode constituted the case group while the contralateral eyes without attack consisted of the control group. Ophthalmic examinations including slit-lamp examination, best-corrected visual acuity, intraocular pressure and visual ...
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    15. Age-related Changes in Crystalline Lens Tilt and Decentration A Swept-source Optical Coherence Tomography Study

      Age-related Changes in Crystalline Lens Tilt and Decentration A Swept-source Optical Coherence Tomography Study
      Purpose: To investigate the age-related tilt and decentration of crystalline lenses using a swept-source optical coherence tomography biometer (Casia 2, TOMEY, Japan). Setting: Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China Design: Cross-sectional study Methods: The direction and magnitude of the crystalline lens were evaluated in 230 participants with ages ranging from 7 to 90 years using swept-source optical coherence tomography. The participants were divided into four age groups, and ...
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    16. Assessment of macular microvasculature features before and after vitrectomy in the idiopathic macular epiretinal membrane using a grading system: An optical coherence tomography angiography study

      Assessment of macular microvasculature features before and after vitrectomy in the idiopathic macular epiretinal membrane using a grading system: An optical coherence tomography angiography study
      Purpose To evaluate pre‐ and postoperative microvasculature features in eyes with different idiopathic macular epiretinal membrane (iERM) classifications using optical coherence tomography angiography (OCTA). Methods In this retrospective study, 100 eyes with iERM were enrolled; 62 eyes underwent pars plana vitrectomy (PPV). All iERM eyes were evaluated and graded using optical coherence tomography (OCT). According to the thickness of the fovea relative to the surrounding macula from OCT radial line ...
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  2. About Wenzhou Medical College

    Wenzhou Medical College

    Wenzhou Medical College, designated as a key university in Zhejiang, is an institution of higher learning under the leadership of Zhejiang Provincial Government. Its history can be traced back to Zhejiang Specialized Medical School established in Hangzhou in 1912, named "Zhejiang Second Medical College" at that time. In August 1958, part of Zhejiang Medical College was moved from Hangzhou to Wenzhou and began recruiting 5-year fulltime program students, hence the name Wenzhou Medical College (WMC).