1. Wenzhou Medical College

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    1. Mentioned In 118 Articles

    2. Automated delineation of corneal layers on OCT images using a boundary-guided CNN

      Automated delineation of corneal layers on OCT images using a boundary-guided CNN
      Accurate segmentation of corneal layers depicted on optical coherence tomography (OCT) images is very helpful for quantitatively assessing and diagnosing corneal diseases ( e.g ., keratoconus and dry eye). In this study, we presented a novel boundary-guided convolutional neural network (CNN) architecture (BG-CNN) to simultaneously extract different corneal layers and delineate their boundaries. The developed BG-CNN architecture used three convolutional blocks to construct two network modules on the basis of the ...
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    3. Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia

      Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia
      Background/aims: Pathological myopia (PM) is a leading cause of blindness worldwide. We aimed to evaluate microvascular and chorioretinal changes in different stages of myopia with wide-field (WF) swept-source (SS) optical coherence tomography angiography (OCTA). Methods: This prospective cross-sectional observational study included 186 eyes of 122 patients who had undergone imaging between November 2018 and October 2020. Vessel density (VD) and vessel skeletonised density (VSD) of superficial capillary plexus, deep ...
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    4. Retinal Vascular Changes during the Menstrual Cycle Detected with Optical Coherence Tomography Angiography

      Retinal Vascular Changes during the Menstrual Cycle Detected with Optical Coherence Tomography Angiography
      Purpose. To evaluate the effects of the menstrual cycle on the retinal vascular status of healthy women by optical coherence tomography angiography (OCTA). Materials and Methods. Healthy women with regular natural menstrual cycles of 28 to 30 days were recruited for this prospective study. The womens retinal vascular status was measured by OCTA at 3 time points: the early follicular, ovulatory, and midluteal phases of the menstrual cycle. The main ...
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    5. Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography

      Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography
      Purpose . To measure the macular retinal vessel density (VD) and peripapillary retinal nerve fiber layer (RNFL) in primary angle-closure suspects (PACS) by Angio-OCT to be compared with normal subjects. Methods . Primary angle-closure suspect patients and normal subjects were enrolled in this study. The demographic and clinical characteristics of all subjects, such as RNFL thickness, retinal vessel density, and ocular perfusion pressure, were compared. Results . No significant difference was found in ...
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    6. Macular perfusion density evaluation in constant and intermittent exotropia by means of optical coherence tomography angiography

      Macular perfusion density evaluation in constant and intermittent exotropia by means of optical coherence tomography angiography
      Background: To quantify and compare retinal microvascular features using optical coherence tomography angiography (OCTA) in constant (XT) and intermittent exotropia (IXT). Methods: An observational cross-sectional study was conducted from September 2020 to November 2020 at the Affiliated Eye Hospital of Wenzhou Medical University. OCTA examination was performed to evaluate the macular perfusion density of the deep capillary plexus (DCP), superficial capillary plexus (SCP), and foveal avascular zone (FAZ) parameters in ...
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    7. Effect of Age and Cycloplegia on the Morphology of the Human Crystalline Lens: a Swept-source Optical Coherence Tomography Study

      Effect of Age and Cycloplegia on the Morphology of the Human Crystalline Lens: a Swept-source Optical Coherence Tomography Study
      Purpose: To evaluate the effect of age and cycloplegia on the morphology of crystalline lens using a swept-source optical coherence tomography (SS-OCT) system. Setting: hospital. Design: Prospective cross-sectional study. Methods: Seventy six individuals (age range, 18 to 86 years) were recruited. The parameters including anterior chamber depth (ACD), the radii of curvature of the anterior and posterior surface of crystalline lens (ALR and PLR), lens thickness (LT), lens equatorial diameter ...
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    8. Spectral-Domain Optical Coherence Tomography Imaging of the Typical cystoid degeneration

      Spectral-Domain Optical Coherence Tomography Imaging of the Typical cystoid degeneration
      Purpose: To describe the spectral-domain optical coherence tomography (SD-OCT) features of typical cystoid degeneration. Methods: This was a retrospective study of 11 eyes with typical cystoid degeneration (TCD). All patients had a complete ocular examination, ultra-widefield (UWF) pseudocolor fundus photography and SD-OCT with a 55 wide-field lens. We analyzed the cross-sectional structural information of SD-OCT imaging with TCD. Results: On SD-OCT, the TCD regions exhibited rolling hills patterns with irregularly ...
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    9. Identification of peripheral anterior synechia with anterior segment optical coherence tomography

      Identification of peripheral anterior synechia with anterior segment optical coherence tomography
      Purpose: To generate a model that evaluates the presence and extent of peripheral anterior synechia (PAS) based on anterior segment optical coherence tomography (AS-OCT). Methods: The extent of PAS involvement in the eyes of patients with angle closure was assessed by indentation gonioscopy, and the part of non-PAS and PAS were assigned into two groups (NPAS and PAS). Anterior chamber angles were then imaged by AS-OCT with light-emitting diode (LED ...
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    10. Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography

      Changes in circumpapillary retinal vessel density after acute primary angle closure episode via OCT angiography
      Purpose: To investigate the changes and evaluate the diagnosis value of circumpapillary vessel density (VD) in cases of acute primary angle closure (APAC). Design: Case-control study. Methods: APAC patients with a history of unilateral acute attack were enrolled. The eyes with acute episode constituted the case group while the contralateral eyes without attack consisted of the control group. Ophthalmic examinations including slit-lamp examination, best-corrected visual acuity, intraocular pressure and visual ...
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    11. Age-related Changes in Crystalline Lens Tilt and Decentration A Swept-source Optical Coherence Tomography Study

      Age-related Changes in Crystalline Lens Tilt and Decentration A Swept-source Optical Coherence Tomography Study
      Purpose: To investigate the age-related tilt and decentration of crystalline lenses using a swept-source optical coherence tomography biometer (Casia 2, TOMEY, Japan). Setting: Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China Design: Cross-sectional study Methods: The direction and magnitude of the crystalline lens were evaluated in 230 participants with ages ranging from 7 to 90 years using swept-source optical coherence tomography. The participants were divided into four age groups, and ...
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    12. Assessment of macular microvasculature features before and after vitrectomy in the idiopathic macular epiretinal membrane using a grading system: An optical coherence tomography angiography study

      Assessment of macular microvasculature features before and after vitrectomy in the idiopathic macular epiretinal membrane using a grading system: An optical coherence tomography angiography study
      Purpose To evaluate pre‐ and postoperative microvasculature features in eyes with different idiopathic macular epiretinal membrane (iERM) classifications using optical coherence tomography angiography (OCTA). Methods In this retrospective study, 100 eyes with iERM were enrolled; 62 eyes underwent pars plana vitrectomy (PPV). All iERM eyes were evaluated and graded using optical coherence tomography (OCT). According to the thickness of the fovea relative to the surrounding macula from OCT radial line ...
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    13. Assessment of Choroidal Vascularity and Choriocapillaris Blood Perfusion in Anisomyopic Adults by SS-OCT/OCTA

      Assessment of Choroidal Vascularity and Choriocapillaris Blood Perfusion in Anisomyopic Adults by SS-OCT/OCTA
      Purpose: To explore the association of choroidal vascularity and choriocapillaris blood perfusion with myopic severity in anisomyopes. Methods: Refractive error, axial length (AL), and other biometric parameters were measured in 34 anisomyopic young adults. Macular choroidal thickness (ChT) and choroidal vascularity, including total choroidal area (TCA), luminal area (LA), stromal area (SA), and choroidal vascularity index (CVI), were determined from swept-source optical coherence tomography (SS-OCT) vertical and horizontal B-scans. The ...
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    14. Detection of neovascularisation in the vitreoretinal interface slab using widefield swept-source optical coherence tomography angiography in diabetic retinopathy

      Detection of neovascularisation in the vitreoretinal interface slab using widefield swept-source optical coherence tomography angiography in diabetic retinopathy
      Aims To compare the efficacy of diabetic retinal neovascularisation (NV) detection using the widefield swept-source optical coherence tomography angiography (WF SS-OCTA) vitreoretinal interface (VRI) Angio slab and SS-OCT VRI Structure slab. Methods A prospective, observational study was performed at Massachusetts Eye and Ear from January 2019 to June 2020. Patients with proliferative diabetic retinopathy (PDR), patients with non-proliferative diabetic retinopathy and patients with diabetes but without diabetic retinopathy were included ...
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    15. Morphological changes in and quantitative analysis of macular retinal microvasculature by optical coherence tomography angiography in hypertensive retinopathy

      Morphological changes in and quantitative analysis of macular retinal microvasculature by optical coherence tomography angiography in hypertensive retinopathy
      Hypertension is a serious global health problem. Hypertensive retinopathy is generally considered to be a predictor of vascular disease elsewhere in the human body. In the past few decades, a variety of grading systems have been proposed for hypertensive retinopathy. However, these grading systems have some limitations. This study utilized optical coherence tomography angiography (OCTA) to investigate the morphological changes and macular retinal microvasculature in depth among 100 patients with ...
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    16. Evaluation of microvasculature alterations in convalescent Vogt-Koyanagi-Harada disease using optical coherence tomography angiography

      Evaluation of microvasculature alterations in convalescent Vogt-Koyanagi-Harada disease using optical coherence tomography angiography
      Purpose To evaluate the microvasculature alterations in convalescent Vogt-Koyanagi-Harada (VKH) disease using optical coherence tomography angiography (OCTA), and to explore the association between microvasculature and the presence of sunset glow fundus (SGF). Methods A cross-sectional study was conducted with 28 VKH patients at convalescent stage and 25 healthy individuals. Both eyes of each participant were enrolled. The VKH patients were classified into two subgroups based on the existence of SGF ...
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  2. About Wenzhou Medical College

    Wenzhou Medical College

    Wenzhou Medical College, designated as a key university in Zhejiang, is an institution of higher learning under the leadership of Zhejiang Provincial Government. Its history can be traced back to Zhejiang Specialized Medical School established in Hangzhou in 1912, named "Zhejiang Second Medical College" at that time. In August 1958, part of Zhejiang Medical College was moved from Hangzhou to Wenzhou and began recruiting 5-year fulltime program students, hence the name Wenzhou Medical College (WMC).