1. Wenzhou Medical College

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    1. Mentioned In 84 Articles

    2. Deep learning based early stage diabetic retinopathy detection using optical coherence tomography

      Deep learning based early stage diabetic retinopathy detection using optical coherence tomography
      Diabetic retinopathy (DR) is one of the leading causes of preventable blindness globally. Performing retinal examinations on all diabetic patients is an unmet need, and detection at an early stage can provide better control of the disease. The objective of this study is to provide an optical coherence tomography (OCT) image based diagnostic technology for automated early DR diagnosis, including at both grades 0 and 1. This work can help ...
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    3. Relationship of Posterior Capsular Opacification and Capsular Bend Type Investigation Based on Swept-source Optical Coherence Tomography

      Relationship of Posterior Capsular Opacification and Capsular Bend Type Investigation Based on Swept-source Optical Coherence Tomography
      Purpose : To investigate the relationship between capsular bend type and posterior capsule opacification (PCO) at a three-dimensional (3D) level using high-speed swept-source optical coherence tomography (SS-OCT). Methods : This was a retrospective study. A total of 99 eyes that underwent standard cataract surgery with phacoemulsification 2 years ago were analyzed. Standard SS-OCT radial scanning was performed in all eyes and the obtained photos were used for morphological observations of the capsular ...
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    4. Precise delineation and tumor localization based on novel image registration strategy between optical coherence tomography and computed tomography in the radiotherapy of intraocular cancer

      Precise delineation and tumor localization based on novel image registration strategy between optical coherence tomography and computed tomography in the radiotherapy of intraocular cancer
      Radiation-associated toxicities due to sophisticated ocular anatomy and shape variability of organs at risk (OARs) are major concerns during external beam radiation therapy (EBRT) of patients with intraocular cancer. A novel two-step image registration strategy between optical coherence tomography (OCT) and computed tomography (CT) images was proposed and validated to precisely localize the target in the EBRT of patients with intraocular cancer. Specifically, multiple features from OCT and CT images ...
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    5. Evaluation of choroidal thickness in amblyopia using optical coherence tomography

      Evaluation of choroidal thickness in amblyopia using optical coherence tomography
      Objective: To investigate the choroidal thickness in children with amblyopia through spectral-domain optical coherence tomography. Methods: A total of 31 children with unilateral amblyopia and 31 right eyes of controls with normal vision were enrolled in the study. The choroidal thickness was measured directly below the fovea and at 12 other locations: 1, 2 and 3mm superior, temporal, inferior, and nasal to the fovea. All the parameters were compared between ...
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    6. Semi-Supervised Automatic Segmentation of Layer and Fluid Region in Retinal Optical Coherence Tomography Images Using Adversarial Learning

      Semi-Supervised Automatic Segmentation of Layer and Fluid Region in Retinal Optical Coherence Tomography Images Using Adversarial Learning
      Optical coherence tomography (OCT) is a primary imaging technique for ophthalmic diagnosis due to its advantages in high resolution and non-invasiveness. Diabetes is a chronic disease, which could cause retinal layer deformation and fluid accumulation. It might increase the risk of blindness, and thus, it is important to monitor the morphology change of the retinal layer and fluid accumulation for diabetes patients. Due to the existence of deformation and fluid ...
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    7. Integrating Handcrafted and Deep Features for Optical Coherence Tomography Based Retinal Disease Classification

      Integrating Handcrafted and Deep Features for Optical Coherence Tomography Based Retinal Disease Classification
      Deep Neural Networks (DNNs) have been widely applied to automatic analysis of medical images for disease diagnosis, and to help human experts by efficiently processing immense amounts of images. While handcrafted feature has been used for eye disease detection or classification since the 1990s, DNN was recently adopted in this area and showed very promising performance. Since handcrafted and deep feature can extract complementary information, we propose in this paper ...
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    8. Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification With Swept-Source Optical Coherence Tomography

      Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification With Swept-Source Optical Coherence Tomography
      To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT).To observe the 60 eyes of 60 patients in our study.
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    9. Lens nuclear opacity quantitation with long-range swept-source optical coherence tomography: correlation to LOCS III and a Scheimpflug imaging-based grading system

      Lens nuclear opacity quantitation with long-range swept-source optical coherence tomography: correlation to LOCS III and a Scheimpflug imaging-based grading system
      Purpose To quantitate lens nuclear opacity using long-range swept-source optical coherence tomography (SS-OCT) images and to evaluate the correlation of this method to Lens Opacities Classification System III (LOCS III) and a Scheimpflug imaging-based grading system (Pentacam Nuclear Stage function; PNS). Methods This study enrolled 120 participants (120 eyes) with age-related nuclear cataracts. The best-corrected visual acuity (BCVA), LOCS III nuclear opalescence (NO) and nuclear colour (NC) were obtained. The ...
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    10. Evaluation of peripapillary choroidal distribution in children by enhanced depth imaging optical coherence tomography

      Evaluation of peripapillary choroidal distribution in children by enhanced depth imaging optical coherence tomography
      Background To evaluate the peripapillary choroidal thickness (PPCT) in Chinese children aged 6 to 12 years old and to analyze correlative factors. Methods PPCT was measured with enhanced depth imaging optical coherence tomography (EDI-OCT) in 154 children (76 myopes and 78 emmetropia) aged 6 to 12 years, with spherical equivalent refractive errors between +0.50 and5.50 diopters(D). Peripapillary choroidal imaging was performed using circular scans of a diameter ...
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    11. Short term effect of choroid thickness in the horizontal meridian detected by spectral domain optical coherence tomography in myopic children after orthokeratology

      Short term effect of choroid thickness in the horizontal meridian detected by spectral domain optical coherence tomography in myopic children after orthokeratology
      AIM : To investigate choroidal thickness changes in the horizontal meridian after orthokeratology. METHODS : This is a prospective cross-sectional observed study. Subjects (n=30; 11.31.7y) with low-to-moderate myopia (-1.0 to -6.0 diopters), wore orthokeratology (Ortho-K) lenses for 3mo. Before and after Ortho-K, OCT scans were made through the fovea in the horizontal meridian. Choroid thickness around the fovea was acquired by custom software. The analyzed regions along ...
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    12. Leveraging WeChat Social-Media and Messaging Platform to Increase Physical Activity in Chinese Glaucoma Patients

      Leveraging WeChat Social-Media and Messaging Platform to Increase Physical Activity in Chinese Glaucoma Patients
      ...weeks randomized control trial with three total study visits. 80 patients from an academic glaucoma clinic in Wenzhou Medical College will be randomized into two groups. The intervention group will be enrolled into an Of...
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    13. Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

      Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography
      Purpose . To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods . Twenty participants (4 males and 16 females, 23.03.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours ...
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    14. Inner Retinal Microvasculature Damage Correlates With Outer Retinal Disruption During Remission in Behçet's Posterior Uveitis by Optical Coherence Tomography Angiography

      Inner Retinal Microvasculature Damage Correlates With Outer Retinal Disruption During Remission in Behçet's Posterior Uveitis by Optical Coherence Tomography Angiography
      Purpose : To quantify the inner retinal vascular changes that occur in the superficial and deep layers in patients with Behet's disease (BD) in remission using optical coherence tomography angiography (OCTA) and to evaluate the associations with outer retinal structure. Methods : Nineteen eyes from 19 patients with BD in remission were enrolled, including 10 eyes with less than five ocular attacks ( n 5) and nine eyes with five or more ...
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    15. Axial elongation measured by long scan depth optical coherence tomography during pilocarpine-induced accommodation in intraocular lens-implanted eyes

      Axial elongation measured by long scan depth optical coherence tomography during pilocarpine-induced accommodation in intraocular lens-implanted eyes
      We used an ultra-long scan depth optical coherence tomography (UL-OCT) system to investigate changes in axial biometry of pseudophakic eyes during pilocarpine- induced accommodation. The right eyes from 25 healthy subjects (age range 49 to 84 years) with an intraocular lens (IOL) were imaged twice in the non-accommodative and the accommodative states. A custom-built UL-OCT instrument imaged the whole eye. Then accommodation was induced by two drops of 0.5 ...
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    16. Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography

      Precision of a new ocular biometer in eyes with cataract using swept source optical coherence tomography combined with Placido-disk corneal topography
      The present study was to assess the precision (repeatability and reproducibility) of a new optical biometer (OA-2000, Tomey, Japan) based on swept-source optical coherence tomography (SS-OCT) and Placido disk topography in eyes with cataracts. Seventy-eight eyes from seventy-eight patients with cataracts were evaluated. Axial length (AL), anterior chamber depth (ACD), keratometry (K) over a 2.5mm and 3.0mm diameter, lens thickness (LT), central corneal thickness (CCT) and white-to-white (WTW ...
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  2. About Wenzhou Medical College

    Wenzhou Medical College

    Wenzhou Medical College, designated as a key university in Zhejiang, is an institution of higher learning under the leadership of Zhejiang Provincial Government. Its history can be traced back to Zhejiang Specialized Medical School established in Hangzhou in 1912, named "Zhejiang Second Medical College" at that time. In August 1958, part of Zhejiang Medical College was moved from Hangzhou to Wenzhou and began recruiting 5-year fulltime program students, hence the name Wenzhou Medical College (WMC).