1. Wakayama Medical University

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    1. Mentioned In 143 Articles

    2. Assessment by Optical Coherence Tomography of Stent Struts Across Side Branch – Comparison of Bare-Metal Stents and Drug-Eluting Stents –

      Assessment by Optical Coherence Tomography of Stent Struts Across Side Branch – Comparison of Bare-Metal Stents and Drug-Eluting Stents –
      ... Ozaki1), Kumiko Hirata1), Masato Mizukoshi1) and Takashi Akasaka1) 1) Department of Cardiovascular Medicine, Wakayama Medical University Background: Late stent thrombosis (LST) after drug-eluting stent (DES) implantatio...
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    3. Clinical Classification and Plaque Morphology Determined by Optical Coherence Tomography in Unstable Angina Pectoris

      Clinical Classification and Plaque Morphology Determined by Optical Coherence Tomography in Unstable Angina Pectoris
      Unstable angina pectoris (UAP) is categorized with the Braunwald classification. However, the association of clinical presentation and plaque structure/function has not yet been elucidated in relation to cause. We used optical coherence tomography to investigate this relation. One hundred fifteen patients with primary UAP were categorized according to the Braunwald classification. Patients with class I UAP had the highest frequency of ulcers without fibrous cap disruption (p = 0.003 ...
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    4. The Effect of Lipid and Inflammatory Profiles on the Morphological Changes of Lipid-Rich Plaques in Patients With Non-ST-Segment Elevated Acute Coronary Syndrome: Follow-Up Study by Optical Coherence Tomography and Intravascular Ultrasound

      The Effect of Lipid and Inflammatory Profiles on the Morphological Changes of Lipid-Rich Plaques in Patients With Non-ST-Segment Elevated Acute Coronary Syndrome: Follow-Up Study by Optical Coherence Tomography and Intravascular Ultrasound
      ... Kimura, MD, PhD, Masato Mizukoshi, MD, PhD, Takashi Akasaka, MD, PhD* Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan * Reprint requests and correspondence: Dr. Takashi Akasaka, Depar...
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    5. Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris

      Association of monocyte subset counts with coronary fibrous cap thickness in patients with unstable angina pectoris
      Abstract: Objectives: We examined whether distinct monocyte subsets relate in specific ways to coronary fibrous cap thickness (FCT) in patients with unstable angina pectoris (UAP).Methods: Forty patients with UAP who underwent percutaneous coronary intervention were enrolled in this study. The changes in the non-culprit FCT were assessed by optical coherence tomography (OCT) at baseline and after 9 months. The distinct monocyte subsets (CD14+CD16−CCR2+ and CD14+CD16+CX3CR1 ...
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    6. Relation of Microchannel Structure Identified by Optical Coherence Tomography to Plaque Vulnerability in Patients With Coronary Artery Disease

      Relation of Microchannel Structure Identified by Optical Coherence Tomography to Plaque Vulnerability in Patients With Coronary Artery Disease
      Increased neovascularization in atherosclerotic plaques is associated with plaque vulnerability. The high resolution of optical coherence tomography (OCT) might provide a chance to directly visualize plaque neovascularization in vivo. The aim of the present study was to investigate the relation between microchannels in culprit plaques identified by OCT and plaque vulnerability in patients with coronary artery disease. A total of 63 consecutive patients with coronary artery disease who had undergone ...
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    7. Optical coherence tomography in unprotected left main coronary artery stenting

      Optical coherence tomography in unprotected left main coronary artery stenting
      Aims: Delayed or incomplete stent endothelisation and stent malapposition may predispose to DES thrombosis that can be catastrophic event in the left main coronary artery (LMCA). OCT can accurately identify stents struts and arterial tissue, but is limited by the need of vessel blood clearance and penetration; also no data exists on its use in LMCA. We sought to verify whether optical coherence tomography (OCT) can accurately assess arterial wall ...
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    8. Multiple Coronary Lesion Instability in Patients With Acute Myocardial Infarction as Determined by Optical Coherence Tomography

      Autopsy studies have suggested that acute myocardial infarction (AMI) represents a pan-coronary process of vulnerable plaque development. We performed multifocal optical coherence tomographic (OCT) examination to compare coronary lesion instability between AMI and stable angina pectoris (SAP). A total of 42 patients with AMI (n = 26) or SAP (n = 16) who had multivessel disease and underwent multivessel coronary intervention were enrolled in the present study. The OCT examination was performed ...
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    9. Activated Platelet is Associated With Subclinical Stent Thrombosis Detected by Optical Coherence Tomography

      Activated Platelet is Associated With Subclinical Stent Thrombosis Detected by Optical Coherence Tomography
      Backgrounds: While stent thrombosis is a critical issue in the drug-eluting stent era, there are few monitoring markers for stent thrombosis. Optical coherence tomography (OCT) introducing as a high-resolution modality allows us to assess plaque characteristics, including in-stent micro-thrombus. We hypothesized that in vivo activated platelet was associated with in-stent thrombus formation. The aim of this study was to investigate the relationship between in vivo platelet activity and in-stent thrombus ...
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    10. Impact of Culprit Lesion Characteristics on Microvascular Obstruction in Patients With Acute Coronary Syndrome: An Optical Coherence Tomography and Cardiac Magnetic Resonance Imaging Study

      Background: The degree of myocardial damage is an important determinant of clinical outcomes in patients with acute coronary syndrome (ACS). We have reported that lesion characteristics are associated with slow flow phenomenon. The aim of this study was to investigate whether culprit lesion characteristics identified by optical coherence tomography (OCT) were associated with microvascular obstruction (MVO) assessed by contrast-enhanced magnetic resonance imaging (ce-MRI) in patients with ACS. Methods: We enrolled ...
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    11. Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis

      ... Royal Brompton Hospital and Imperial College, London, UK 6 Massachusetts General Hospital, Boston, MA, USA 7 Wakayama Medical University, Wakayama, Japan 8 Medical Center Cleveland, Cleveland, OH, USA 9 Spedali Riuniti,...
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    12. 59 Optical Coherence Tomography Papers Presentations at Transcatheter Cardiovascular Therapeutics Conference (TCT 2009)

      59 Optical Coherence Tomography Papers Presentations at Transcatheter Cardiovascular Therapeutics Conference (TCT 2009)
      Optical Coherence Tomography (OCT) continues to make substantial progress in cardiovascular applications as evidence by the impressive number of OCT papers presented at this years Transcatheter Cardiovascular Therapeutics Conference (TCT 2009). The table below contains a list of the presenters and titles. Additional information on these talks can be found in the Symposia CD when it is released. See the Cardiology category above for additional information on OCT in cardiology.
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  2. About Wakayama Medical University

    Wakayama Medical University

    Wakayama Medical University is a public university in Wakayama, Wakayama, Japan. The predecessor of the school was founded in 1945, and it was chartered as a university in 1948.