1. Wakayama Medical University

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    1. Mentioned In 148 Articles

    2. Natural Course of Lipid-rich Plaques Assessed with Combination of Intra-vascular Ultrasound and Optical Coherence Tomography

      Background Identification of coronary lesions with morphological characteristic of "rupture-prone plaques" is not sufficient. We examined the natural history of non-culprit lipid-rich plaques in patients with acute coronary syndrome (ACS). Methods Fifty patients with ACS who underwent percutaneous coronary intervention (PCI) were enrolled. We retrospectively assessed the extent of residual non-culprit lipid-rich plaques and these fibrous cap thickness (FCT) by use of intra-vascular ultrasound (IVUS) and optical coherence tomography (OCT ...
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    3. Distribution and Frequency of Thin-Capped Fibroatheromas and Ruptured Plaques in the Entire Culprit Coronary Artery in Patients With Acute Coronary Syndrome as Determined by Optical Coherence Tomography

      The aim of this study was to investigate the distribution and frequency of thin-capped fibroatheromas (TCFAs) within the entire length of culprit coronary arteries in patients with acute coronary syndrome. Our population was drawn from 43 consecutive patients with acute coronary syndrome (with or without ST-segment elevation) who underwent optical coherence tomography to visualize the entire culprit coronary artery using a nonocclusive optical coherence tomographic technique. Patients were categorized divided ...
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    4. Cardiac Optical Coherence Tomography

      Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially ...
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    5. “Continuous-Flushing” OCT Identifies Vulnerable Plaques

      New findings show that using non-occlusive optical coherence tomography (OCT) in patients with acute coronary syndromes can help identify vulnerable thin-capped fibroatheromas (TCFAs) and ruptured plaques in culprit coronary arteries. The study, published online ahead of print in the August 4, 2008, issue of American Journal of Cardiology, also found TCFAs to significantly correlate with high plasma levels of C-reactive protein (CRP). Atsushi Tanaka, MD, and colleagues from Wakayama University ...
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    6. Comparison of Vascular Response After Sirolimus-Eluting Stent Implantation Between Patients With Unstable and Stable Angina Pectoris: A Serial Optical Coherence Tomography Study

      ...ma, Japan. * Reprint requests and correspondence: Dr. Takashi Akasaka, Department of Cardiovascular Medicine, Wakayama Medical University, 811-1, Kimiidera, Wakayama, 641-8509, Japan. (Email: Objectives: The aim of the p...
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    7. Effect of statin therapy on coronary fibrous-cap thickness in patients with acute coronary syndrome: Assessment by optical coherence tomography study

      Background The thickness of coronary fibrous caps is a major determinant of vulnerable plaques. Several clinical trials have suggested that statin therapy could stabilize vulnerable plaques. Recently, optical coherence tomography (OCT) has been proposed as an effective histology-resolution imaging modality for assessing such micro-structural changes. Methods Forty AMI patients with hyperlipidemia were enrolled and underwent percutaneous coronary intervention (PCI). They were divided into two groups; statin treatment group (n = 23 ...
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    8. Identification of multiple plaque ruptures by optical coherence tomography in a patient with acute myocardial infarction: a three-vessel study

      Optical coherence tomography (OCT) is a new imaging modality capable of obtaining cross-sectional images of coronary vessels with a high resolution of about 10 µm, which is about 10-fold greater than that of intravascular ultrasound. A 57-year-old man was admitted to our hospital with acute posterior myocardial infarction. An emergency coronary angiography demonstrated 99% stenosis (TIMI 2 flow) in segment 11 of the left circumflex artery, and 75% stenosis in ...
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    9. Safety and Feasibility of an Intravascular Optical Coherence Tomography Image Wire System in the Clinical Setting

      Optical coherence tomography (OCT) is a fiber-optic technology that enables high-resolution intracoronary imaging. The aim of this study was to evaluate the safety and feasibility of intracoronary imaging with OCT in the clinical setting; 76 patients with coronary artery disease from 8 centers were enrolled. The OCT imaging system (ImageWire, Light Imaging Inc., Westford, Massachusetts) consists of a 0.006 inch fiber-optic core that rotates within a 0.016 inch ...
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    10. Optical coherence tomography after cutting balloon angioplasty

      Optical coherence tomography (OCT) is a recently developed optical imaging technique that provides high-resolution (approximately 10–20 µm) cross-sectional images of vessels. A 74-year-old man was admitted for chest pain. A coronary angiogram showed diffuse in-stent restenosis of an Express (Boston Scientific Corporation and Medinol Ltd) 2.75 x 15 mm stent which had been implanted in the left anterior descending coronary artery six months earlier (panel A; arrow). Using ...
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    11. 136-148 of 148 « 1 2 3 4 5 6 7 8 9 10
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  2. About Wakayama Medical University

    Wakayama Medical University

    Wakayama Medical University is a public university in Wakayama, Wakayama, Japan. The predecessor of the school was founded in 1945, and it was chartered as a university in 1948.