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2. Optical coherence tomography in coronary atherosclerosis assessment and intervention
  
  Explore Nature Publishing Group Apr 30 2022 Cardiology
  
  Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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  Mentions: Brigham and Women’s Hospital Johns Hopkins University Massachusetts Institute of Technology
3. Combined Use of Multiple Intravascular Imaging Techniques in Acute Coronary Syndrome
  
  Explore Frontiers Feb 4 2022 Cardiology
  
  Recent advances in intravascular imaging techniques have made it possible to assess the culprit lesions of acute coronary syndrome (ACS) in the clinical setting. Intravascular ultrasound (IVUS) is the most commonly used intravascular imaging technique that provides cross-sectional images of coronary arteries. IVUS can assess plaque burden and vessel remodeling. Optical coherence tomography (OCT) is a high-resolution (10 m) intravascular imaging technique that uses near-infrared light. OCT can identify key ...
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  Mentions: University of Ulsan Wakayama Medical University Shanghai Jiao Tong University
4. Automatic Coregistration Between Coronary Angiography and Intravascular Optical Coherence Tomography
  
  Explore ScienceDirect Sep 26 2021 Cardiology
  
  This study sought to evaluate a novel approach for automatic coregistration of optical coherence tomography (OCT) and coronary angiography. Lumen diameters and side branches from both coronary angiography and OCT were used to create 2 feature sets. Subsequently, a 2-step coregistration approach was performed on the feature sets for matching of each OCT cross section on the angiographic centerline. For validation, all side branches with 1.0 mm diameter were ...
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  Mentions: Wakayama Medical University Shanghai Jiao Tong University
5. Usefulness of optical coherence tomography with angiographic coregistration in the guidance of coronary stent implantation
  
  Explore Home - Springer Jul 22 2021 Cardiology
  
  Optical coherence tomography (OCT)-angiography coregistration during stent implantation may be useful to avoid geographical mismatch and incomplete lesion coverage. Untreated lipid-rich plaque at stent edge is associated with subsequent stent edge restenosis. The present study sought to compare the frequency of untreated lipid-rich plaque at the stent edge between OCT-guided percutaneous coronary intervention (PCI) with and without OCT-angiography coregistration. We investigated 398 patients who underwent OCT-guided stent implantation (n ...
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  Mentions: Wakayama Medical University
6. Evaluation of coronary plaques and atherosclerosis using optical coherence tomography
  
  Explore Taylor & Francis Online Apr 8 2021 Cardiology
  
  Introduction: Coronary angiography (CAG) is the standard modality for assessing coronary stenosis; however, it has limitations in assessing coronary plaque morphology. Optical coherence tomography (OCT) is a high-resolution (10-20m) light-based intravascular imaging technique that can identify more detailed coronary plaque morphology compared to other intravascular imaging modalities. OCT is remarkable for characterizing fibrous, fibrocalcific, and lipid-rich plaques. The capabilities of OCT are well suited for discriminating three types of unstable ...
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  Mentions: Wakayama Medical University
7. 1.1 μm waveband tunable laser using emission-wavelength-controlled InAs quantum dots for swept-source optical coherence tomography applications
  
  Explore IOPscience Mar 2 2021 Tunable Sources
  
  In this study, an optical gain chip using emission-wavelength-controlled self-assembled InAs quantum dots (QDs) was developed for swept-source optical coherence tomography (SS-OCT) applications. The optical characterizations indicated that the QDs emission wavelength and optical gain spectra were controlled in the 1.1 m waveband by optimizing the QDs growth conditions. This waveband is useful for obtaining a large imaging depth of OCT because of an optimal balance between absorption and ...
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  Mentions: Wakayama Medical University
8. Optical coherence tomography detection of vulnerable plaques at high risk of developing acute coronary syndrome
  
  Explore Journals Feb 26 2021 Cardiology
  
  Aims: The ability of optical coherence tomography (OCT) to detect plaques at high risk of developing acute coronary syndrome (ACS) remains unclear. The aim of this study was to evaluate the association between non-culprit plaques characterized as both lipid-rich plaque (LRP) and thin-cap fibroatheroma (TCFA) by OCT and the risk of subsequent ACS events at the lesion level. Methods and results: In 1378 patients who underwent OCT, 3533 non-culprit plaques ...
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  Mentions: Cardiovascular Research Foundation Wakayama Medical University
9. Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence
  
  Explore eurointervention.pcronline.com Feb 2 2021 Cardiology
  
  Background Intravascular optical coherence tomography (IVOCT) enables detailed plaque characterisation in-vivo, but visual assessment is time-consuming and subjective. Aims This study aims to develop and validate an automatic framework for IVOCT plaque characterisation using artificial intelligence (AI). Methods IVOCT pullbacks from 5 international centres were analysed in a corelab, annotating basic plaque components, inflammatory markers and other structures. A deep convolutional network with encoding-decoding architecture and pseudo-3D input was developed ...
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  Mentions: Cardiovascular Research Foundation Wakayama Medical University Chinese Academy of Sciences
10. Impact of Optical Coherence Tomography Imaging on Decision-Making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes
  
  Explore jstage.jst.go.jp Jan 22 2021 Cardiology
  
  Background: Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and optimization. The aim of the present study was to compare lumen expansion of stent-treated lesions immediately after the procedure for ACS between OCT-guided PCI and angiography-guided PCI.Methods and Results:This study investigated stent-treated lesions immediately after PCI for ACS by using quantitative coronary angiography ...
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  Mentions: Wakayama Medical University
11. Saline as an alternative to radio-contrast for optical coherence tomography guided percutaneous coronary intervention: A prospective comparison
  
  Explore ScienceDirect Jan 21 2021 Cardiology
  
  Objectives: To do a quantitative comparison of saline and contrast Frequency domain optical coherence tomography (FD-OCT) during percutaneous coronary intervention (PCI) optimisation. Methods: 13 pairs of OCT runs were analysed, wherein each pair consisted of a contrast run and a heparinized saline run taken in the same coronary artery at the same position. Quantitative analysis was done comparing minimal lumen area (MLA), proximal reference diameter (PRD), distal reference diameter (DRD ...
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  Mentions: Wakayama Medical University
12. Prevalence, Features, and Prognosis of Artery-to-Artery Embolic ST-Segment-Elevation Myocardial Infarction: An Optical Coherence Tomography Study
  
  Explore Home | AHA/ASA Journals Dec 1 2020 Cardiology
  
  Background The major underlying mechanisms contributing to acute coronary syndrome are plaque rupture, plaque erosion, and calcified nodule. Artery-to-artery embolic myocardial infarction (AAEMI) was defined as ST-segment-elevation myocardial infarction caused by migrating thrombus formed at the proximal ruptured plaque. The aim of this study was to investigate the prevalence and clinical features of AAEMI by using optical coherence tomography. Methods and Results This study retrospectively enrolled 297 patients with ST-segment-elevation ...
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  Mentions: Wakayama Medical University
13. NIRS-IVUS for Differentiating Coronary Plaque Rupture, Erosion and Calcified Nodule in Acute Myocardial Infarction
  
  Explore ScienceDirect Nov 23 2020 Cardiology
  
  Objectives This study sought to investigate the ability of combined near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) to differentiate plaque rupture (PR), plaque erosion (PE), or calcified nodule (CN) in acute myocardial infarction (AMI). Background Most acute coronary syndromes occur from coronary thrombosis based on PR, PE, or CN. In vivo differentiation among PR, PE, and CN is a major challenge for intravascular imaging. Methods The study enrolled 244 patients with ...
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  Mentions: Wakayama Medical University
14. Supporting evidence for ST-segment elevation myocardial infarction from optical coherence tomography
  
  Explore eurointervention.pcronline.com Nov 17 2020 Cardiology
  
  A 56-year-old male with current smoking and dyslipidemia was admitted to our hospital because of anterior ST-segment elevation myocardial infarction (STEMI). Echocardiogram showed akinesis in the apex of the left ventricle, and the ejection fraction was 55%. There was no evidence of atrial fibrillation, cardiac shunts or any cardiac thrombus. He had no history of the emotional stress, cocaine intake or thrombophilia. And, also there was no episode that suspected ...
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  Mentions: Wakayama Medical University
15. Comparison of Optical Flow Ratio and Fractional Flow Ratio in Stent-Treated Arteries Immediately After Percutaneous Coronary Intervention
  
  Explore jstage.jst.go.jp Oct 31 2020 Cardiology
  
  Background: Optical flow ratio (OFR) is a recently developed method for functional assessment of coronary artery disease based on computational fluid dynamics of vascular anatomical data from intravascular optical coherence tomography (OCT). The purpose of this study was to investigate the relationship between OFR and fractional flow reserve (FFR) in stent-treated arteries immediately after percutaneous coronary intervention (PCI). Methods and Results: The OFR and FFR were measured in 103 coronary ...
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  Mentions: Wakayama Medical University
16. OPtical Coherence Tomography Guided Coronary Stent IMplantation Compared to Angiography: A Multicenter Randomized TriaL in PCI
  
  Explore eurointervention.pcronline.com Sep 5 2020 Cardiology
  
  AIMS: Randomized trials have demonstrated improvement in clinical outcomes with intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI. The ILUMIEN III trial demonstrated non-inferiority of an optical coherence tomography (OCT)- versus IVUS-guided PCI strategy in achieving similar post-PCI lumen dimensions. ILUMIEN IV is a large-scale, multicenter, randomized trial designed to demonstrate the superiority of OCT- versus angiography-guided stent implantation in patients with high-risk clinical characteristics (diabetes ...
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  Mentions: Columbia University Mount Sinai School of Medicine Cardiovascular Research Foundation
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