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2. Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): one-year angiographic and clinical results
  
  Explore Journals Jun 27 2017 Cardiology
  
  ...ial online, Appendix). An independent data and safety monitoring committee monitored the safety of the trial. Wakayama Medical University (Wakayama, Japan), one of the clinical sites, undertook co-ordination of this tria...
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  Mentions: Terumo Corporation Wakayama Medical University European Society of Cardiology
3. Suboptimal agreement between optical coherence tomography and near-infrared spectroscopy for identification of lipid-laden plaque
  
  Explore eurointervention.org Jun 20 2017 Cardiology
  
  Recently developed intracoronary imaging techniques allow real-time, in vivo identification of lipid in atherosclerotic plaques. Optical coherence tomography (OCT), a light-based imaging technique with high axial resolution (10-20 m), identifies lipid-laden plaques as signal-poor regions with diffuse borders. A validation study performed versus histopathology confirmed the high sensitivity (90% to 94%) and specificity (90% to 92%) of OCT to identify lipid-laden plaques 1 . Near-infrared spectroscopy (NIRS) detects lipid-laden plaque by ...
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  Mentions: Wakayama Medical University Takashi Kubo Takashi Akasaka
4. Morphological and pharmacological determinants of peri-procedural myocardial infarction following elective stent implantation: Optical coherence tomography sub-analysis of the PRASFIT-Elective study
  
  Explore ScienceDirect Jun 17 2017 Cardiology
  
  Background Previous studies have suggested that peri-procedural myocardial infarction (PMI) following percutaneous coronary intervention (PCI) is associated with adverse short- and long-term outcomes, and several morphological predictors of PMI have been studied. However, the determinants of PMI under novel anti-platelet therapy are not fully elucidated. Methods and results PRASFIT-Elective is a multicenter, parallel-group study of PCI patients in non-acute settings receiving either prasugrel or clopidogrel in addition to aspirin. Among ...
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  Mentions: Wakayama Medical University Kobe University Graduate School of Medicine
5. Analysis of neointima development in flow diverters using optical coherence tomography imaging
  
  Explore jnis.bmj.com Jun 17 2017 Ophthalmology
  
  Background Flow diverters are used for the treatment of intracranial aneurysms. Surface modification may decrease the thrombogenicity of flow diverters but the details are unknown. Optical coherence tomography (OCT) is an intravascular imaging test with high resolution which identifies neointimal growth over stents. We compared the development of neointima in a flow diverter and stents with and without surface modification in a swine model. Methods In this study we implanted ...
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  Mentions: Wakayama Medical University Yonsei University
6. Prognosis of spontaneous coronary artery dissection treated by percutaneous coronary intervention with optical coherence tomography
  
  Explore ScienceDirect May 16 2017 Cardiology
  
  Background Although about half of patients with spontaneous coronary artery dissection (SCAD) face ongoing necrosis, conservative therapy is recommended due to a high complication rate in angiography-guided percutaneous coronary intervention (PCI). The aim of this study was to investigate clinical outcomes of SCAD treated by optical coherence tomography (OCT)-guided PCI. Methods This study consisted of consecutive 306 patients with acute coronary syndrome (ACS) who underwent OCT-guided PCI. Based on ...
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  Mentions: Wakayama Medical University Akio Kuroi Atsushi Tanaka
7. Impact of Plaque Rupture Detected by Optical Coherence Tomography on Transmural Extent of Infarction After Successful Stenting in ST-Segment Elevation Acute Myocardial Infarction
  
  Explore ScienceDirect May 1 2017 Cardiology
  
  bjectives The aim of the present study was to investigate the association between plaque rupture (PR) assessed by optical coherence tomography (OCT), and the transmural extent of infarction (TEI) assessed by contrast-enhanced cardiac magnetic resonance imaging (CE-CMR) in ST-segment elevation myocardial infarction (STEMI) patients after primary percutaneous coronary intervention (PCI). Background PR is associated with larger infarct size as assessed by cardiac enzymes in STEMI patients. CE-CMR is a favorable ...
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  Mentions: Wakayama Medical University Takashi Kubo Takashi Tanimoto
8. Gallium nitride light sources for optical coherence tomography
  
  Explore Conference Proceedings Mar 1 2017 Broadband Sources
  
  The advent of optical coherence tomography (OCT) has permitted high-resolution, non-invasive, in vivo imaging of the eye, skin and other biological tissue. The axial resolution is limited by source bandwidth and central wavelength. With the growing demand for short wavelength imaging, super-continuum sources and non-linear fibre-based light sources have been demonstrated in tissue imaging applications exploiting the near-UV and visible spectrum. Whilst the potential has been identified of using gallium ...
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  Mentions: University of Sheffield Wakayama Medical University Richard A. Hogg
9. Comparison between Preoperative Optical Coherence Tomography Findings of Carotid Artery Stenosis and Pathological Specimen of Removed Carotid Plaque: Case Report
  
  Explore jstage.jst.go.jp Feb 11 2017 Cardiology
  
  Objective: Optical coherence tomography (OCT) has recently been applied for the characterization of carotid plaques, but few studies have compared OCT findings with findings from histopathologic examination of carotid plaques. We consider the accuracy, problems, and limitation of OCT findings by comparing OCT findings of carotid artery stenosis and pathological specimen of removed carotid plaque, and confirm that the interpretation of coronary artery findings of OCT can be applied to ...
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  Mentions: Wakayama Medical University
10. Automatic Fibroatheroma Identification from Intravascular Optical Coherence Tomography Images
  
  Explore Apache Tomcat Feb 7 2017 Cardiology
  
  Vulnerable plaque identification is important in coronary heart disease diagnosis. Intravascular Optical Coherence Tomography (IVOCT) is an imaging modality which can characterize the appearance of vulnerable plaques. However, current used manual reading of the images is time consuming and subjective. Therefore, an automated and objective assessment of the plaque is necessary. This paper proposes a method for automatic identification of potential vulnerable plaque such as fibroatheroma in IVOCT images. In ...
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  Mentions: Wakayama Medical University Atsushi Tanaka Nicolas Foin
11. Thrombus and Plaque Erosion Characterized by Optical Coherence Tomography in Patients With Vasospastic Angin
  
  Explore ScienceDirect Dec 13 2016 Cardiology
  
  Introduction and objectives Vasospastic angina (VSA) can result in endothelial damage and thrombus formation. The aim of this study was to evaluate the incidence of thrombus and plaque characteristics at coronary spasm segments compared with nonspasm segments by using optical coherence tomography (OCT) in patients with suspected VSA. Methods One hundred and eighty-three patients with suspected VSA were enrolled in this study. The ergonovine provocation test was performed in all ...
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  Mentions: Seoul National University University of Ulsan Wakayama Medical University
12. Optical Coherence Tomography Predictors for Edge Restenosis After Everolimus-Eluting Stent Implantation
  
  Explore Circulation Oct 4 2016 Cardiology
  
  Background Stent edge restenosis (SER) remains a potential limitation of drug-eluting stents. The aim of this study was to determine optical coherence tomography (OCT) predictors for angiographic late SER after everolimus-eluting stent implantation. Methods and Results We retrospectively analyzed 319 patients who underwent OCT immediately after everolimus-eluting stent implantation and scheduled 9- to 12-month follow-up angiography. The binary angiographic SER rate was 10% (32/319) in the patients, 8.4 ...
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  Mentions: Wakayama Medical University Takashi Kubo Hironori Kitabata
13. Angiographic, optical coherence tomography and histology findings from combination of a drug-coated balloon with an everolimus-eluting stent in a porcine mode
  
  Explore Elsevier Health Aug 18 2016 Cardiology
  
  Background We designed a porcine model to compare the angiographic, optical coherence tomography (OCT) and histological findings of implanting an everolimus-eluting stent (EES) in the same segment of the coronary artery pre-treated with a drug-coating balloon (DCB; paccocath as carrier) with EES alone and DCB plus a bare metal stent (BMS). Methods Seven female swine averaging 46.02.4 kg were treated by random assignment as follows: DCB followed by ...
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  Mentions: Wakayama Medical University Takashi Kubo Takashi Akasaka
14. High-resolution and nondestructive profile measurement by spectral-domain optical coherence tomography with a visible broadband light source for optical-device fabrication
  
  Explore IOPscience Jul 29 2016 NDE/NDT
  
  We developed a spectral-domain optical coherence tomography (OCT) using a visible broadband light source (vis-OCT) for application to high-resolution and nondestructive profile measurement and imaging in semiconductor optical-device fabrication. By using visible broadband light centered at 625 nm and with spectral bandwidth of 260 nm, an axial resolution of 0.69 m in air was obtained. This was effective for inspection of a transparent photoresist film with thickness of 12 ...
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  Mentions: Wakayama Medical University
15. Assessment of Vascular Response after Stent Implantation by Intracoronary Optical Coherence Tomograph
  
  Explore synergy May 24 2016 Cardiology
  
  Optical coherence tomography (OCT) is a high resolution (10-20 m) imaging modality that provides microscopic visualization of the coronary artery including vascular response after stent implantation. Compared to conventional intravascular ultrasound, OCT can more clearly identify findings immediately after stent implantation, such as tissue protrusion, stent edge dissection, and incomplete stent strut apposition. Furthermore, OCT allows clinicians to accurately assess the late acquired stent malapposition and strut coverage which could ...
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  Mentions: Wakayama Medical University Takashi Kubo Hironori Kitabata
16. Optimal Imaging Matches Intravascular Ultrasound for Guiding PCI
  
  Explore dicardiology.com May 21 2016 Cardiology
  
  ...e a class IIa recommendation," he said. Commenting on the findings, Takashi Akasaka, professor of medicine at Wakayama Medical University, Wakayama, Japan, said, "There has previously been no direct comparative data for ...
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  Mentions: Wakayama Medical University Takashi Kubo Takashi Akasaka
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