1. Wakayama Medical University

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    1. Mentioned In 78 Articles

    2. Association between P-selectin Glycoprotein Ligand-1 and Pathogenesis in Acute Coronary Syndrome Assessed by Optical Coherence Tomography

      Association between P-selectin Glycoprotein Ligand-1 and Pathogenesis in Acute Coronary Syndrome Assessed by Optical Coherence Tomography

      Objective Although monocytes appear to be actively involved in the onset of acute coronary syndrome (ACS), they are heterogenous in human peripheral blood. How up-regulation of monocyte subsets leads to coronary plaque rupture followed by thrombus formation remains unclear. Recent studies have shown that P-selectin glycoprotein ligand-1 (PSGL-1) is involved in monocyte activation in patients with thrombus formation. We therefore investigated the relationship between the expression of PSGL-1 on monocyte subsets and thrombus formation using frequency-domain optical coherence tomography (FD-OCT) in patients with ACS. Methods We enrolled a total of 100 individuals in this study: patients with acute myocardial infarction ...

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    3. A Case of In-Stent Neoatherosclerosis 10 Years after Carotid Artery Stent Implantation: Observation with Optical Coherence Tomography and Plaque Histological Findings

      A Case of In-Stent Neoatherosclerosis 10 Years after Carotid Artery Stent Implantation: Observation with Optical Coherence Tomography and Plaque Histological Findings
      ...u MASUO^1), Katsuhisa HIRAYAMA^1), Yuji UEMATSU^1), Naoyuki NAKAO^1) 1) Department of Neurological Surgery, Wakayama Medical University -Submit Released 2013/11/20 Received 2013/02/28 Accepted 2013/04/09 Keywords:...
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    4. Comparison of diagnostic accuracy between multidetector computed tomography and virtual histology intravascular ultrasound for detecting optical coherence tomography-derived fibroatheroma

      Comparison of diagnostic accuracy between multidetector computed tomography and virtual histology intravascular ultrasound for detecting optical coherence tomography-derived fibroatheroma
      ...uted tomography Virtual histology IVUS Optical coherence tomography Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan Department of Cardiovascular Medicine, Social Insurance Kinan Ho...
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    5. Intravascular Ultrasound Versus Optical Coherence Tomography Guidance

      Intravascular Ultrasound Versus Optical Coherence Tomography Guidance

      IVUS Versus Angiography Guidance for DES PlacementFirst Author/Study (Ref. #), Year (Study)nStudy PopulationStudy DesignIVUS Criteria for Optimal ExpansionCriteria FulfilledMain Outcome MeasuresResultsRoy et al. (2), 20081,768De novo native coronary lesions, restenotic and SVG lesionsSingle-center registryDiscretion of the treating operator—Definite stent thrombosis and MACE at 12 monthsIVUS better (stent thrombosis and TLR)Classen et al. (3), 2011 (MATRIX)1,504 (SES)De novo native coronary and restenotic lesionsMulticenter registryDiscretion of the treating operator—30-day, 1-yr, and 2-yr rates of death/MI, MACE, and stent thrombosisIVUS betterPark et al. (4), 2009682Left main lesionsMulticenter registryDiscretion of the treating operator3-yr mortalityIVUS betterChieffo ...

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    6. Monolithically grown multi-color InAs quantum dots as a spectral-shape-controllable near-infrared broadband light source

      Monolithically grown multi-color InAs quantum dots as a spectral-shape-controllable near-infrared broadband light source

      We have grown monolithic multi-color InAs quantum dots (QDs) for use as a near-infrared (NIR) broadband light source. Our previously developed rotational metal mask enables selective-area growth of QD ensembles with emission peak wavelengths controlled by strain-reducing layers thicknesses, varying the emission approximately 1.2–1.3  μ m. The peak shift value was up to 120 nm, and a combined 160-nm-bandwidth emission spectrum was achieved. Further, the emission spectra shapes were controlled using specific optical excitation powers for each QD ensemble. These results demonstrate the effectiveness of multi-color QDs as a spectrum-shape-controllable NIR broadband light source, particularly suited for optical ...

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    7. Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

      Inter-Scan Reproducibility of Geometric Coronary Artery Measurements Using Frequency-Domain Optical Coherence Tomography

      Frequency-domain optical coherence tomography (FD-OCT) is a novel technology which provides high-resolution cross-sectional images of coronary arteries. The aim of this study was to evaluate the inter-scan reproducibility of geometric FD-OCT measurements in the clinical setting. We examined 20 coronary lesions using FD-OCT. Following the FD-OCT image acquisition (1 st pullback), and after the disengagement and re-engagement of the guiding catheter, an additional acquisition (2 nd pullback) was performed using a new FD-OCT catheter. There was excellent correlation for minimum lumen area ( r = 0.99, P < 0.001), lesion length ( r = 0.99, P < 0.001) and lumen volume ( r ...

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    8. Coronary Superficial and Spotty Calcium Deposits in Culprit Coronary Lesions of Acute Coronary Syndrome as Determined by Optical Coherence Tomography

      Coronary Superficial and Spotty Calcium Deposits in Culprit Coronary Lesions of Acute Coronary Syndrome as Determined by Optical Coherence Tomography
      ... * Atsushi Tanaka, MD, * Toshio Imanishi, MD, * Takashi Akasaka, MD Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan Received 14 November 2012; received in revised form 26 February ...
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    9. St. Jude Medical Announces Launch of 3-D Vessel Reconstruction Technology in Japan

      St. Jude Medical Announces Launch of 3-D Vessel Reconstruction Technology in Japan

      St. Jude Medical Press Release - St. Jude Medical, Inc. (NYSE:STJ), a global medical device company, today announced the launch of its ILUMIEN ™ OPTIS ™ System, a next-generation technology designed to help physicians make personalized stenting decisions based on each patient’s unique anatomy and disease state. The new ILUMIEN OPTIS system remains the only combined Fractional Flow Reserve (FFR) and intravascular Optical Coherence Tomography (OCT) imaging technology platform. Together, FFR and OCT offer physicians a physiological and anatomical view of the coronary vessels to help diagnose and treat coronary artery disease. The ILUMIEN OPTIS system provides enhancements to the ILUMIEN ...

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    10. Cardiac Allograft Vasculopathy Progression Associated With Intraplaque Neovascularization

      Cardiac Allograft Vasculopathy Progression Associated With Intraplaque Neovascularization

      A 52-year-old man underwent scheduled cardiac catheterization for assessment of cardiac allograft vasculopathy (CAV) at 3 and 12 months after heart transplantation (HTx). Intravascular ultrasound showed only mild CAV in the left anterior descending coronary artery (LAD) at 3 months ( B , Online Video 1 ). However, at 12 months, CAV progression was detected, predominantly in the proximal LAD ( A and C3 , Online Video 2 ). Corresponding optical coherence tomography images revealed the presence of many no-signal tubuloluminal structures within the fibrous plaque in serial frames. Parts of those structures were found to be connected to the vessel lumen, indicating neovascularization ( D2, D3 ...

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    11. Difference in neointimal appearance between early and late restenosis after sirolimus-eluting stent implantation assessed by optical coherence tomography

      Difference in neointimal appearance between early and late restenosis after sirolimus-eluting stent implantation assessed by optical coherence tomography

      Objectives: Late in-stent restenosis (ISR) is an important clinical issue in the drug-eluting stent era. Autopsy studies have reported different underlying mechanisms between early ISR and late ISR. The aim of the present study was to compare the neointimal tissue appearance between early ISR (<1 year) and late ISR (>1 year) after sirolimus-eluting stent (SES) implantation using optical coherence tomography (OCT). Materials and methods: We examined the neointimal tissue appearance in 48 ISR lesions after SES implantation [30 early ISR lesions (8±1 months after stenting) and 18 late ISR lesions (34±14 months after stenting)] by OCT. ISR was ...

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  2. About Wakayama Medical University

    Wakayama Medical University

    Wakayama Medical University is a public university in Wakayama, Wakayama, Japan. The predecessor of the school was founded in 1945, and it was chartered as a university in 1948.