1. Victor X. D. Yang

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    1. Mentioned In 103 Articles

    2. Endovascular Cerebral Venous Sinus Imaging with Optical Coherence Tomography

      Endovascular Cerebral Venous Sinus Imaging with Optical Coherence Tomography
      BACKGROUND AND PURPOSE: Imaging of the cerebral venous sinuses has evolved Substantially during the past 2 decades, and most recently intravascular sinus imaging with sonography has shed light on the pathophysiology of sinus thrombosis and intracranial hypertension. Optical coherence tomography is the highest resolution intravascular imaging technique available but has not been previously used in cerebral sinus imaging. The purpose of this study was to develop a preclinical animal model ...
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    3. Endovascular optical coherence tomography imaging in cerebrovascular disease

      Endovascular optical coherence tomography imaging in cerebrovascular disease
      Endovascular optical coherence tomography (OCT) is the highest resolution imaging modality currently available with spatial resolution of 10 m. Although originally developed for interventional cardiology, the ability to visualize the luminal environment and anatomy, along with the stent-vessel interaction could be of great utility for various cerebrovascular diseases, and the adoption of endovascular OCT imaging in the evolving field of interventional neuroradiology seems instinctive. The purpose of this study is ...
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    4. Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU

      Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU
      We recently proposed an optical coherence tomographic angiography (OCTA) algorithm, Gabor optical coherence tomographic angiography (GOCTA), which can extract microvascular signals from a spectral domain directly with lower computational complexity compared to other algorithms. In this manuscript, we combine a programmable swept source, an OCT complex signal detecting unit, and graphics process units (GPU) to achieve a real-time en-face GOCTA system for human skin microvascular imaging. The programmable swept source ...
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    5. Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model

      Optical coherence tomography imaging after endovascular thrombectomy: a novel method for evaluating vascular injury in a swine model
      Although studies have shown that some degree of iatrogenic endothelial injury occurs during endovascular thrombectomy (EVT), the clinical significance of such injury is uncertain. Furthermore, it is likely that iatrogenic effects such as endothelial denudation, intimal dissection, and tunica media edema will have varying clinical implications. The purpose of this study was to assess the feasibility of endovascular optical coherence tomography (OCT) in quantifying vessel injury in real time after ...
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    6. Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed

      Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed
      We previously proposed a Gabor optical coherence tomography angiography (GOCTA) algorithm for spectral domain optical coherence tomography (SDOCT) to extract microvascular signals from spectral fringes directly, with speed improvement of 4 to 20 times over existing methods. In this manuscript, we explored the theoretical basis of GOCTA with comparison of experimental data using solid and liquid displacement sample targets, demonstrating that the majority of the GOCTA sensitivity advantage over speckle ...
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    7. Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation

      Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation
      Evidence regarding the role of early (24 hours) antithrombotics post-revascularization with either intravenous thrombolysis (IVT), endovascular thrombectomy (EVT), or a combination of both remains scarce. In 2018 the American Heart Association/American Stroke Association changed their recommendation, stating that the risk of antithrombotic therapy within the first 24 hours after treatment with IVT (with or without EVT) is uncertain. This was changed after data emerged that early antithrombotics may be ...
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    8. Optical coherence tomography–guided flow diversion for aneurysmal treatment

      Optical coherence tomography–guided flow diversion for aneurysmal treatment
      A 28-year-old man presenting with right third nerve palsy was diagnosed with a giant unruptured aneurysm supplied by the right posterior communicating and cerebral arteries (figure 1, A and B). The aneurysm was treated with flow-diverting stent-assisted coiling. Two months later, he presented with new-onset left-sided weakness, and MRI showed increased edema in the thalamus (figure 1C) and increased aneurysm size and no filling. There was no evidence of stent ...
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    9. Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases

      Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases
      Studies evaluating individuals for endothelial injury after endovascular thrombectomy (EVT) have been done by means of retrieved human thrombus, MR vessel-wall imaging, and animal histopathological studies. These techniques have limitations, because MR imaging has insufficient spatial resolution to directly visualize endothelium, and histopathological examinations are performed ex vivo and are unable to provide real-time patterns of injury. The purpose of the current study was to obtain in vivo intraluminal imaging ...
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    10. Optical coherence tomography for dynamic axial correction of an optical end-effector for robot-guided surgical laser ablation

      Optical coherence tomography for dynamic axial correction of an optical end-effector for robot-guided surgical laser ablation
      Robot-guided laser ablation for surgical applications potentially offers many advantages compared to by-hand mechanical tissue cutting. However, given that tissue can be rough and/or uneven, ablation quality can be compromised if the beam waist deviates significantly from the target tissue surface. Therefore, we present a method that uses optical coherence tomography (OCT) for dynamic refocusing of robot-guided surgical laser ablation. A 7-DOF robotic manipulator with an OCT-equipped optical payload ...
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    11. Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease

      Optical Coherence Tomography as an Adjunct During Carotid Artery Stenting for Carotid Atherosclerotic Disease
      Purpose Carotid artery stenting (CAS) has been proven to decrease the risk of stroke in symptomatic patients with moderate/high-grade carotid stenosis; however, there is an increased periprocedural risk of stroke with CAS compared to carotid endarterectomy. The goal of this article is to report the utilization of endovascular optical coherence tomography (OCT) during CAS to aid in the identification of stent malapposition, plaque prolapse, and adjacent residual thrombus that ...
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    12. 2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography

      2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography
      In this manuscript, a two-dimensional (2D) micro-electro-mechanical system (MEMS)-based, high-speed beam-shifting spectral domain optical coherence tomography (MHB-SDOCT) is proposed for speckle noise reduction and absolute flow rate measurement. By combining a zigzag scanning protocol, the frame rates of 45.2 Hz for speckle reduction and 25.6 Hz for flow rate measurement are achieved for in-vivo tissue imaging. Phantom experimental results have shown that by setting the incident beam ...
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    13. Beam-shifting technique for speckle reduction and flow rate measurement in optical coherence tomography

      Beam-shifting technique for speckle reduction and flow rate measurement in optical coherence tomography
      In this Letter, we propose a beam-shifting optical coherence tomography scheme for speckle reduction and blood flow rate calculation, where variations of the speckle pattern and Doppler angle were generated by parallel shifting of the sample beam incident on the objective lens. The resultant optical coherent tomography images could then be averaged for speckle noise reduction and simultaneously analyzed for flow rate measurement. The performance of the proposed technique was ...
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    14. Buffer-averaging super-continuum source based spectral domain optical coherence tomography for high speed imaging

      Buffer-averaging super-continuum source based spectral domain optical coherence tomography for high speed imaging
      In super-continuum (SC) source based spectral domain optical coherence tomography (SC-SDOCT), the stability of the power spectral density (PSD) has a significant impact on OCT system sensitivity and image signal to noise ratio (SNR). High speed imaging decreases the camera's exposure time, thus each A-scan contained fewer laser pulse excited SC wideband emissions, resulting in a decrease of SNR. In this manuscript, we present a buffer-averaging SC-SDOCT (BASC-SDOCT) to ...
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    15. Carotid artery stenting with optical coherence tomography

      Carotid artery stenting with optical coherence tomography
      A 61-year-old man underwent a left cervical internal carotid artery stenting following a recent ischemic stroke. Postoperative angiography was satisfactory and did not reveal any in-stent filling defect ( figure 1A ). Optical coherence tomography (OCT) probe was used to visualize the endoluminal area following stenting. OCT confirmed optimum placement of the stent and reveled a small plaque protrusion from the stent struts following deployment ( figure 1B ).
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  2. About Victor X. D. Yang

    Victor X. D. Yang

    Victor Yang, PhD, is an Assistant Professor in the Department of Electrical and Computer Engineering and the Department of Physics at Ryerson University in Canada. Research Focus: Optical coherence tomography, intra-operative fluorescence imaging, photodynamic therapy, micro-machined electro-mechanical probes/catheters.

  3. Quotes

    1. Young Ryerson researchers are working with the best in the field, and I think they can compete on the world stage in the near future.
      In An engineer and doctor, researcher Victor Yang develops medical technology to detect and treat disease
    2. These collaborations are out-of-the-box partnerships that lead to creative thinking and practical problem solving. They just reflect our university's history and traditional strength, in a new arena.
      In An engineer and doctor, researcher Victor Yang develops medical technology to detect and treat disease