1. Vasile Sirbu

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    1. Mentioned In 27 Articles

    2. Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium

      Optical Coherence Tomography Findings in Patients with Coronary Stent Thrombosis: A Report of the PREvention of Late Stent Thrombosis by an Interdisciplinary Global European Effort (PRESTIGE) Consortium
      Background Stent thrombosis (ST) is a serious complication following coronary stenting. Intravascular optical coherence tomography (OCT) may provide insights into mechanistic processes leading to ST. We performed a prospective, multicenter study to evaluate OCT findings in patients with ST. Methods Consecutive patients presenting with ST were prospectively enrolled in a registry using a centralized telephone registration system. After angiographic confirmation of ST, OCT imaging of the culprit vessel was performed ...
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    3. Fate of Nonculprit Plaques in Patients With STEMI Undergoing Primary PCI Followed by Statin Therapy : A Serial Optical Coherence Tomography Analysis From the OCTAVIA Study

      Fate of Nonculprit Plaques in Patients With STEMI Undergoing Primary PCI Followed by Statin Therapy : A Serial Optical Coherence Tomography Analysis From the OCTAVIA Study
      ...ihiro Shimamura, Davide Capodanno, Guilherme F. Attizzani, Massimo Fineschi, Giuseppe Musumeci, Ugo Limbruno, Vasile Sirbu, Micol Coccato, Leonardo De Luca You can get the full-text article here... ...if you are:...
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    4. The OPTIS Integrated System: real-time, co-registration of angiography and optical coherence tomography

      The OPTIS Integrated System: real-time, co-registration of angiography and optical coherence tomography
      The efficacy of an IVUS-guided stent implantation strategy to improve acute results and clinical outcome has been described previously. OCT is another technique which allows high-resolution intracoronary imaging. However, the use of invasive imaging modalities to guide PCI has, as yet, played a limited role in current clinical practice. This may be partly explained by the expertise required for interpretation and clinical decision making. We present a novel technology which ...
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    5. Impact of Culprit Plaque and Atherothrombotic Components on Incomplete Stent Apposition in Patients With ST-Elevation Myocardial Infarction Treated With Everolimus-Eluting Stents – An OCTAVIA Substudy –

      Impact of Culprit Plaque and Atherothrombotic Components on Incomplete Stent Apposition in Patients With ST-Elevation Myocardial Infarction Treated With Everolimus-Eluting Stents – An OCTAVIA Substudy –
      Background: The role of culprit plaque and related atherothrombotic components on incomplete stent apposition (ISA) occurrence after primary percutaneous coronary intervention (p-PCI) is unknown. Methods and Results: ST-segment elevation myocardial infarction (STEMI) patients undergoing p-PCI with an everolimus-eluting stent were prospectively investigated with optical coherence tomography (OCT) of the infarct-related artery before, after stenting and at 9 months. OCT data, aspirated thrombus and serum inflammatory biomarkers were analyzed. 114 patients ...
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    6. Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction : Results of the OCTAVIA (Optical Coherence Tomography Assessment of Gender Diversity in Primary Angiop

      Mechanisms of Atherothrombosis and Vascular Response to Primary Percutaneous Coronary Intervention in Women Versus Men With Acute Myocardial Infarction : Results of the OCTAVIA (Optical Coherence Tomography Assessment of Gender Diversity in Primary Angiop
      Objectives This study sought to assess in vivo sex differences in the pathophysiology of ST-segment elevation myocardial infarction (STEMI) and vascular response to primary percutaneous coronary intervention (PCI). Background There is no consensus on whether differences in the pathophysiology of STEMI and response to primary PCI between women and men reflect biological factors as opposed to differences in age. Methods In this prospective, multicenter study, 140 age-matched men and women ...
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    7. Coronary artery disease in systemic sclerosis not clinically apparent: findings from optical coherence tomography

      Coronary artery disease in systemic sclerosis not clinically apparent: findings from optical coherence tomography
      A 42-year-old female was referred for intermittent effort angina. She had low body mass index, no coronary risk factors and an unremarkable past medical history except for a Raynaud's phenomenon. Owing to a normal exercise stress test ( Panel A ), symptoms were initially attributed to anxiety. However, a 24h-EKG monitoring revealed diffuse ST-segment depression during
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    8. Optical coherence tomography versus intravascular ultrasound to evaluate coronary artery disease and percutaneous coronary intervention

      Optical coherence tomography versus intravascular ultrasound to evaluate coronary artery disease and percutaneous coronary intervention
      ...ase and Percutaneous Coronary Intervention ^ * Hiram G. Bezerra, MD, PhD^⁎, * Guilherme F. Attizzani, MD^⁎, * Vasile Sirbu, MD^†, * Giuseppe Musumeci, MD^†, * Nikoloz Lortkipanidze, MD^†, * Yusuke Fujino, MD^⁎, * Wei Wan...
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    9. Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve

      Volumetric assessment of lesion severity with optical coherence tomography: relationship with fractional flow reserve
      Aims: Frequency-domain optical coherence tomography (FD-OCT) provides a rapid tomographic scan of a coronary vessel, with an accurate reconstruction of its lumen profile. An FD-OCT-based metric that corresponds more closely with physiological significance of lesions may enable more precise guidance of interventional procedures. The aim of this feasibility study was to evaluate a new method for quantifying coronary lesion severity that estimates hyperaemic flow resistance of branched vessel segments imaged ...
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    10. Optical coherence tomography evidence of endothelial erosion as a cause of ST-segment elevation myocardial infarction

      Optical coherence tomography evidence of endothelial erosion as a cause of ST-segment elevation myocardial infarction
      High-resolution intracoronary imaging provided relevant insights into the field of pathophysiology of acute coronary syndromes (ACS). Human autopsy studies have shown that endothelial erosion may lead to intravascular thrombosis and acute myocardial infarction. We report the case of a 51-year-old woman presenting with ST-segment elevation ACS. In this patient, frequency domain optical coherence tomography (FD-OCT) was performed into the infarct-related artery, showing in-vivo findings suggestive of endothelial erosion, associated with ...
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      Mentions: Vasile Sirbu
    11. The Role of Optical Coherence Tomography in Clarifying the Mechanisms for Dobutamine Stress Echocardiography-Induced Takotsubo Cardiomyopathy

      The Role of Optical Coherence Tomography in Clarifying the Mechanisms for Dobutamine Stress Echocardiography-Induced Takotsubo Cardiomyopathy
      Takotsubo cardiomyopathy is a clinical disorder characterized by a transient dilatation and akynesis or dyskinesis of the left ventricular (LV) apex, mimicking an anterior wall acute myocardial infarction in the absence of significant coronary artery disease (CAD). It typically occurs during an episode of severe emotional or physical stress. Recent reports suggested the potential of dobutamine stress echocardiography (DSE) in inducing the aforementioned syndrome. The transient dysfunction of the LV ...
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      Mentions: Vasile Sirbu
    12. Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST

      Impact of different stent alloys on human vascular response to everolimus-eluting stent. An optical coherence tomography study. The OCTEVEREST
      Background: New generation drug-eluting stents (DES) incorporate thinner struts and novel alloys to improve clinical performance. Nevertheless, the impact of novel stent materials and designs on human vascular response to DES remains elusive. We sought to evaluate the in-vivo coronary artery response to platinum-chromium (PtCr) versus cobalt-chromium (CoCr) stents featuring the same durable polymer and antiproliferative drug by optical coherence tomography (OCT). Methods and Results: A total of 42 patients ...
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    13. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ...er, MD, Maria D. Radu, MD, Johannes Rieber, MD, Maria Riga, MD, Andrew Rollins, PhD, Mireille Rosenberg, PhD, Vasile Sirbu, MD, Patrick W.J.C. Serruys, MD, PhD, Kenei Shimada, MD, Toshiro Shinke, MD, Junya Shite, MD, Eli...
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    14. Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography

      Serial Assessment of Coronary Artery Response to Paclitaxel-Eluting Stents Using Optical Coherence Tomography
      Background—The paucity of longitudinal, serial high-resolution imaging studies has limited our understanding of in vivo arterial response to drug-eluting stents. We sought to investigate the human coronary response to paclitaxel-eluting stent implantation, using serial optical coherence tomography assessments. Methods and Results—Thirty patients with at least 2 significant coronary lesions in different vessels were treated with a paclitaxel-eluting stent. The most severe stenosis (lesion A) was treated at the ...
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    15. Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging

      Examination of the In Vivo Mechanisms of Late Drug-Eluting Stent Thrombosis: Findings From Optical Coherence Tomography and Intravascular Ultrasound Imaging
      ...and positive vessel remodeling as imaged by IVUS were associated with LST after DES. Giulio Guagliumi, MD*,*, Vasile Sirbu, MD*, Giuseppe Musumeci, MD*, Robert Gerber, MD, Giuseppe Biondi-Zoccai, MD*, Hideyuki Ikejima, M...
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    16. Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)

      Impact of Drug Release Kinetics on Vascular Response to Different Zotarolimus-Eluting Stents Implanted in Patients With Long Coronary Stenoses: The LongOCT Study (Optical Coherence Tomography in Long Lesions)
      ... Coherence Tomography in Long Lesions [LongOCT]; NCT01133925) Giulio Guagliumi, MD*,*, Hideyuki Ikejima, MD*, Vasile Sirbu, MD*, Hiram Bezerra, MD, PhD, Giuseppe Musumeci, MD*, Nikoloz Lortkipanidze, MD*, Luigi Fiocca, M...
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    17. 1-15 of 27 1 2 »
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  2. About Vasile Sirbu

    Vasile Sirbu is from the Cardiovascular Department at Ospedali Riuniti di Bergamo in Bergamo, Italy.