1. Vanderbilt University

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    1. Mentioned In 102 Articles

    2. Cross-Sectional Tracking of Particle Motion in Evaporating Drops: Flow Fields and Interfacial Accumulation

      Cross-Sectional Tracking of Particle Motion in Evaporating Drops: Flow Fields and Interfacial Accumulation
      The lack of an effective technique for three-dimensional flow visualization has limited the experimental exploration of the coffee ring effect to the two dimensional, top-down viewpoint. In this report, high-speed, cross-sectional imaging of the flow fields was obtained by using optical coherence tomography to track particle motion in an evaporating colloidal water drop. This approach enables z-dimensional mapping of primary and secondary flow fields and changes in these fields over ...
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    3. Optical coherence tomography and hyperspectral imaging of vascular recovery in a model of peripheral arterial disease

      Optical coherence tomography and hyperspectral imaging of vascular recovery in a model of peripheral arterial disease
      Peripheral arterial disease (PAD) leads to an increased risk of myocardial infarction and stroke, increased mortality, and reduced quality of life. The mouse hind limb ischemia (HLI) model is the most commonly used system for studying the mechanisms of collateral vessel formation and for testing new PAD therapies, but there is a lack of techniques for acquiring physiologically-relevant, quantitative data intravitally in this model. In this work, non-invasive, quantitative optical ...
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    4. In vivo imaging of gold nanorod contrast agents using photothermal optical coherence tomography

      In vivo imaging of gold nanorod contrast agents using photothermal optical coherence tomography
      Photothermal optical coherence tomography (PT-OCT) has the potential to increase the molecular specificity of OCT for in vivo pre-clinical studies of cancer, in order to better understand drug uptake and treatment response. However, the use of PT-OCT to image contrast agents in vivo has yet to be demonstrated. Here, we characterize PT-OCT imaging of gold nanorod (GNR) contrast agents, and we further apply these techniques for in vivo imaging. The ...
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    5. Contrast enhancement in optical coherence tomography

      Contrast enhancement in optical coherence tomography
      Photothermal heating helps image contrast agents at scarce concentrations over a scattering tissue background. Molecular imaging is a powerful tool for studying disease progression and potential therapies in animals. Optical coherence tomography (OCT) is an important biomedical imaging modality, filling the niche between ultrasound and microscopy. However, OCT suffers from an inherent lack of molecular contrast (the ability to distinguish a molecule of interest from others). This is because the ...
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    6. In vivo photothermal optical coherence tomography of gold nanorod contrast agents

      In vivo photothermal optical coherence tomography of gold nanorod contrast agents
      Photothermal optical coherence tomography (PT-OCT) is a potentially powerful tool for molecular imaging. Here, we characterize PT-OCT imaging of gold nanorod (GNR) contrast agents in phantoms, and we apply these techniques for in vivo GNR imaging. The PT-OCT signal was compared to the bio-heat equation in phantoms, and in vivo PT-OCT images were acquired from subcutaneous 400 pM GNR Matrigel injections into mice. Experiments revealed that PT-OCT signals varied as ...
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    7. Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes

      Dual-modality photothermal optical coherence tomography and magnetic-resonance imaging of carbon nanotubes
      We demonstrate polyethylene-glycol-coated single-walled carbon nanotubes (CNTs) as contrast agents for both photothermal optical coherence tomography (OCT) and magnetic-resonance imaging (MRI). Photothermal OCT was accomplished with a spectral domain OCT system with an amplitude-modulated 750 nm pump beam using 10 mW of power, and T2 MRI was achieved with a 4.7 T animal system. Photothermal OCT and T2 MRI achieved sensitivities of nanomolar concentrations to CNTs dispersed in amine-terminated ...
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    8. A miniature forward-imaging optical coherence tomography (OCT) probe

      A miniature forward-imaging optical coherence tomography (OCT) probe
      Optical coherence tomography (OCT) has had a tremendous global health impact upon the current ability to diagnose, treat, and monitor multiple eye diseases. We propose that a miniature forward-imaging OCT probe can be developed for real-time ocular imaging. A miniature 25-gauge forward-imaging probe was designed and developed to use with an 850 nm spectral-domain optical coherence tomography (SDOCT) system (Bioptigen, Inc. Durham, NC). Imaging parameters were determined. Ocular tissues were ...
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    9. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ... $400,000 University of Alabama at Birmingham $400,000 University of Washington $400,000 Vanderbilt University $400,000 Case Western Reserve University $310,000 University of Texas Me...
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    10. Julie Albon From Cardiff University Receives American Health Assistance Foundation Award for $100k

      Julie Albon From Cardiff University Receives American Health Assistance Foundation Award for $100k
      ...factors but do not have AMD. Jonathan L. Haines, Ph.D., director of the Center for Human Genetics Research at Vanderbilt University, will look for risk genes by comparing the DNA of African Americans with AMD to that of ...
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    11. 76-90 of 102 « 1 2 3 4 5 6 7 »
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  2. About Vanderbilt University

    Vanderbilt University

    Vanderbilt University is a private, nonsectarian, coeducational research university in Nashville, Tennessee, USA. Founded in 1873, the university is named for shipping and rail magnate "Commodore" Cornelius Vanderbilt, who provided Vanderbilt its initial $1 million endowment despite having never been to the South. The Commodore hoped that his gift and the greater work of the university would help to heal the sectional wounds inflicted by the Civil War.