1. UT Southwestern Medical Center

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    1. Mentioned In 63 Articles

    2. Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis

      Longitudinal study of vision and retinal nerve fiber layer thickness in multiple sclerosis
      Objective Cross-sectional studies of optical coherence tomography (OCT) show that retinal nerve fiber layer (RNFL) thickness is reduced in multiple sclerosis (MS) and correlates with visual function. We determined how longitudinal changes in RNFL thickness relate to visual loss. We also examined patterns of RNFL thinning over time in MS eyes with and without a prior history of acute optic neuritis (ON). Methods Patients underwent OCT measurement of RNFL thickness ...
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    3. Macular Atrophy in Birdshot Retinochoroidopathy: An Optical Coherence Tomography and Multifocal Electroretinography Analysis

      Purpose: The purpose of this study was to evaluate macular atrophy by frequency-domain optical coherence tomography (OCT) in patients with birdshot retinochoroidopathy and to compare the resulting thickness measures with visual acuity and multifocal electroretinography (mfERG). Methods: Measures were obtained from 14 eyes of 7 patients with birdshot retinochoroidopathy and 23 normal eyes. Optical coherence tomography-3 measures of macular thinning were related to visual acuity, mfERG response density, and time ...
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    4. Macular Volume Determined by Optical Coherence Tomography as a Measure of Neuronal Loss in Multiple Sclerosis

      Macular Volume Determined by Optical Coherence Tomography as a Measure of Neuronal Loss in Multiple Sclerosis
      ...delphia; Departments of Neurology (Mss Frohman and Conger and Dr Frohman) and Ophthalmology (Dr Frohman), The University of Texas Southwestern Medical Center, Dallas; Departments of Ophthalmology (Dr Burkholder) and Neur...
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    5. Relationship of optic nerve and brain conventional and non-conventional MRI measures and retinal nerve fiber layer thickness, as assessed by OCT and GDx: A pilot study

      BackgroundMeasurement of retinal nerve fiber layer (RNFL) thickness in multiple sclerosis (MS) is gaining increasing attention.ObjectivesTo explore the relationship between RNFL thickness as measured by optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx), and conventional and non-conventional optic nerve and brain MRI measures.MethodsTwelve relapsing–remitting (RR) MS patients (12 affected and 12 unaffected eyes) and 4 age- and sex-matched normal controls (NC) (8 ...
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    6. Corneal Deturgescence after Descemet Stripping Automated Endothelial Keratoplasty Evaluated by Visante Anterior Segment Optical Coherence Tomography

      Purpose: To evaluate postoperative corneal deturgescence after Descemet stripping endothelial keratoplasty (DSAEK) using the Visante anterior segment optical coherence tomography (OCT) system (Carl Zeiss Meditec Inc, Dublin, California, USA).Design: Retrospective case series. Methods: We included 21 eyes (9 males and 12 females; mean age ± standard deviation, 76.3 ± 12 years). The Visante OCT system was used to determine the central and peripheral endothelial keratoplasty graft thickness and total central ...
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    7. Thickness of Receptor and Post-receptor Retinal Layers in Patients with Retinitis Pigmentosa Measured with Frequency-Domain Optical Coherence Tomography (fdOCT)

      PURPOSE: To better understand the effects of retinitis pigmentosa (RP) on post-receptor anatomy by measuring the thickness of the receptor, inner nuclear, retinal ganglion cell (RGC), and retinal nerve fiber layers (RNFL) with frequency-domain optical coherence tomography (fdOCT). METHODS: FdOCT scans were obtained from the horizontal midline in 30 patients with RP and 23 comparable age control subjects. Raw images were exported and the thickness of photoreceptor/RPE, inner nuclear ...
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    8. Reproducibility of Optical Coherence Tomography in Multiple Sclerosis

      Background  Optical coherence tomography (OCT) is a promising new method of quantifying axon thickness in the retinal nerve fiber layer (RNFL) that has been used predominantly by ophthalmologists to monitor glaucoma. Optical coherence tomography is being considered as a potential outcome measure in multiple sclerosis (MS) clinical trials, but no data exist on the reproducibility of this technique in MS centers.Objective  To determine the reproducibility of OCT measurement of ...
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    9. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis.

      Related Articles Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis. Arch Neurol. 2008 Jul;65(7):924-928 Authors: Zaveri MS, Conger A, Salter A, Frohman TC, Galetta SL, Markowitz CE, Jacobs DA, Cutter GR, Ying GS, Maguire MG, Calabresi PA, Balcer LJ, Frohman EM BACKGROUND: Optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx) are similar yet provide ...
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    10. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis

      Background Optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx) are similar yet provide information on different aspects of retinal nerve fiber layer (RNFL) structure (thickness values similar to histology for OCT vs birefringence of microtubules for GDx). Objectives To compare the ability of OCT and GDx to distinguish eyes of patients with multiple sclerosis (MS) from eyes of disease-free controls and thus identify RNFL abnormalities ...
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  2. About UT Southwestern Medical Center

    UT Southwestern Medical Center

    University of Texas Southwestern Medical Center. Part of The University of Texas System, UT Southwestern is governed by the UT Board of Regents. President Dr. Daniel K. Podolsky leads the medical center which includes three degree-granting institutions: UT Southwestern Medical School, UT Southwestern Graduate School of Biomedical Sciences and UT Southwestern School of Health Professions. These three schools train nearly 4,200 medical, graduate and health professions students, residents and postdoctoral fellows each year.