1. Ursula Schmidt-Erfurth

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    1. Mentioned In 134 Articles

    2. Systematic ultrastructural comparison of swept-source and full-depth spectral domain optical coherence tomography imaging of diabetic macular oedema

      Systematic ultrastructural comparison of swept-source and full-depth spectral domain optical coherence tomography imaging of diabetic macular oedema
      Background/Aims Optical coherence tomography (OCT) is commonly used to diagnose and assess diabetic macular oedema (DME). Swept-source OCT (SS-OCT) promises improved imaging depth and more independence from media opacities. Heidelberg Spectralis full-depth imaging (FDI) combines details at different depths to one representation. The aim of this study was to determine the comparability of the imaging methods concerning DME ultrastructure. Methods Two graders assessed the presence of typical DME phenomena ...
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    3. An amplified-target loss approach for photoreceptor layer segmentation in pathological OCT scans

      An amplified-target loss approach for photoreceptor layer segmentation in pathological OCT scans
      Segmenting anatomical structures such as the photoreceptor layer in retinal optical coherence tomography (OCT) scans is challenging in pathological scenarios. Supervised deep learning models trained with standard loss functions are usually able to characterize only the most common disease appeareance from a training set, resulting in suboptimal performance and poor generalization when dealing with unseen lesions. In this paper we propose to overcome this limitation by means of an augmented ...
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    4. Multiclass segmentation as multitask learning for drusen segmentation in retinal optical coherence tomography

      Multiclass segmentation as multitask learning for drusen segmentation in retinal optical coherence tomography
      Automated drusen segmentation in retinal optical coherence tomography (OCT) scans is relevant for understanding age-related macular degeneration (AMD) risk and progression. This task is usually performed by segmenting the top/bottom anatomical interfaces that define drusen, the outer boundary of the retinal pigment epithelium (OBRPE) and the Bruch's membrane (BM), respectively. In this paper we propose a novel multi-decoder architecture that tackles drusen segmentation as a multitask problem. Instead ...
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    5. Comparison of Spectralis and Cirrus spectral domain optical coherence tomography for the objective morphometric assessment of the neuroretinal rim width

      Comparison of Spectralis and Cirrus spectral domain optical coherence tomography for the objective morphometric assessment of the neuroretinal rim width
      Purpose The assessment of cup-disc ratio as a surrogate parameter for the neuroretinal rim width (NRW) of the optic nerve is well established, but prone to human error and imprecision. Objective assessment of the NRW is provided by spectral domain optical coherence tomography (SD-OCT). This study is the first to systematically compare NRW measurements acquired with the Carl Zeiss Meditech Cirrus HD-OCT 5000 and the Heidelberg Engineering Spectralis SD-OCT. Methods ...
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    6. Semi‐automated quantification of geographic atrophy with blue‐light autofluorescence and spectral‐domain optical coherence tomography: a comparison between the region finder and the advanced retinal pigment epithelium tool in the clinical setting

      Semi‐automated quantification of geographic atrophy with blue‐light autofluorescence and spectral‐domain optical coherence tomography: a comparison between the region finder and the advanced retinal pigment epithelium tool in the clinical setting
      Purpose To compare inter‐ and intraobserver reliability and intermodality agreement on quantification of geographic atrophy, using two routinely available quantification tools, based on blue‐light fundus autofluorescence (BAF) and spectral‐domain optical coherence tomography (SD‐OCT). Methods Quantifications of atrophic lesions within the central 5 mm of 30 eyes from 30 patients (mean age: 76.1 years) were independently performed by two clinicians on BAF images using the region finder ...
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    7. Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success

      Summary of 6th International Meeting on OCT Angiography & Advances in OCT in Rome December 2018: A Tremendous Success
      ...arl Csaky, Amani Fawzi, Nadia Waheed, Caroline Baumal, (USA), Albert Augustin, Daniel Pauleikhoff, (Germany), Ursula Schmidt-Erfurth, Wolfgang Drexler (Austria), Anat Loewenstein, Ethan Priel (Israel), Alain Gaudric, Eri...
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    8. Dynamic Changes of Retinal Microaneurysms in Diabetes Imaged With In Vivo Adaptive Optics Optical Coherence Tomography

      Dynamic Changes of Retinal Microaneurysms in Diabetes Imaged With In Vivo Adaptive Optics Optical Coherence Tomography
      Purpose : To prospectively monitor microaneurysms (MAs) in three dimensions using adaptive optics optical coherence tomography (AOOCT). Methods : Patients with diabetes mellitus and parafoveal MAs were included in this longitudinal study. At baseline, MAs were identified in standard fluorescein angiography (FA) and subsequently imaged with an AOOCT prototype, incorporated into an AO fundus camera (RTX1, Imagine Eyes) device. Imaging was repeated every 3 months in each patient to explore the potential ...
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    9. Correlation between morphological characteristics in spectral‐domain‐optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy

      Correlation between morphological characteristics in spectral‐domain‐optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy
      Purpose The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical practice. Methods Retinal thickness (RT), the height, area and volume of subretinal fluid (SRF)/pigment epithelium detachments were evaluated using the standardized procedures of the Vienna Reading ...
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    10. Fully Automated Segmentation of Hyperreflective Foci in Optical Coherence Tomography Images

      Fully Automated Segmentation of Hyperreflective Foci in Optical Coherence Tomography Images
      The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease characteristics. The presence of hyperreflective foci (HRF) is related to disease progression in various retinal diseases. Manual identification of HRF in spectral-domain optical coherence tomography (SD-OCT) scans is error-prone and tedious. We present a fully automated ...
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    11. Comparison of SD-Optical Coherence Tomography Angiography and Indocyanine Green Angiography in Type 1 and 2 Neovascular Age-related Macular Degeneration

      Comparison of SD-Optical Coherence Tomography Angiography and Indocyanine Green Angiography in Type 1 and 2 Neovascular Age-related Macular Degeneration
      Purpose : The purpose of this study is to compare the ability of spectral domain optical coherence tomography angiography (SD-OCTA) and indocyanine green angiography (ICGA) to detect and measure lesion area in patients with type 1 and 2 choroidal neovascularization (CNV). Methods : Types 1 and 2 neovascular AMD (nAMD) were included in this prospective and observational case series. ETDRS best-corrected visual acuity (BCVA), ophthalmic examination with funduscopy, OCTA (AngioVue), fluorescein angiography ...
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    12. Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye

      Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye
      Imaging of the human retina with high resolution is an essential step towards improved diagnosis and treatment control. In this paper, we introduce a compact, clinically user-friendly instrument based on swept source optical coherence tomography (SS-OCT). A key feature of the system is the realization of two different operation modes. The first operation mode is similar to conventional OCT imaging and provides large field of view (FoV) images (up to ...
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    13. THREE-DIMENSIONAL ANALYSIS OF RETINAL MICROANEURYSMS WITH ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY

      THREE-DIMENSIONAL ANALYSIS OF RETINAL MICROANEURYSMS WITH ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To characterize retinal microaneurysms (MAs) in patients with diabetes using adaptive optics optical coherence tomography (AOOCT) and compare details found in AOOCT with those found in commercially available retinal imaging techniques. Methods: Patients with diabetes and MA in the macular area were included in this pilot study. The area of interest, identified in standard fluorescein angiography, was imaged using an AO fundus camera and AOOCT. Microaneurysms were characterized in ...
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    14. Correlation between morphological characteristics in spectral-domain-optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy

      Correlation between morphological characteristics in spectral-domain-optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy
      ...est in any of the products and methods mentioned in this study. Bianca S. Gerendas is a consultant for Roche. Ursula Schmidt-Erfurth is a consultant for Novartis, Genentech, Bayer, Boehringer and Carl Zeiss Meditec....
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    15. IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY

      IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To examine the involvement of the retinal pigment epithelium (RPE) in the presence of vitelliform macular lesions (VML) in Best vitelliform macular dystrophy (BVMD), autosomal recessive bestrophinopathy, and adult-onset vitelliform macular degeneration using polarization-sensitive optical coherence tomography (PS-OCT). Methods: A total of 35 eyes of 18 patients were imaged using a PS-OCT system and blue light fundus autofluorescence imaging. Pathogenic mutations in the BEST1 gene, 3 of which were ...
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  2. About Ursula Schmidt-Erfurth

    Ursula Schmidt-Erfurth

    Ursula M. Schmidt-Erfurth is a Professor of Opththalmology at the Vienna Medical University, Austria.

  3. Quotes

    1. Around 2.5 million people every year develop macular degeneration and diabetes-related retinopathy worldwide...Before OCT, around 20 per cent of patients with this condition worldwide went blind; now, however, it is only two per cent.
      In 200 years of the eye clinic: diseases of the retina can be predicted