1. Ursula Schmidt-Erfurth

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    1. Mentioned In 126 Articles

    2. Fully Automated Segmentation of Hyperreflective Foci in Optical Coherence Tomography Images

      Fully Automated Segmentation of Hyperreflective Foci in Optical Coherence Tomography Images
      The automatic detection of disease related entities in retinal imaging data is relevant for disease- and treatment monitoring. It enables the quantitative assessment of large amounts of data and the corresponding study of disease characteristics. The presence of hyperreflective foci (HRF) is related to disease progression in various retinal diseases. Manual identification of HRF in spectral-domain optical coherence tomography (SD-OCT) scans is error-prone and tedious. We present a fully automated ...
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    3. Comparison of SD-Optical Coherence Tomography Angiography and Indocyanine Green Angiography in Type 1 and 2 Neovascular Age-related Macular Degeneration

      Comparison of SD-Optical Coherence Tomography Angiography and Indocyanine Green Angiography in Type 1 and 2 Neovascular Age-related Macular Degeneration
      Purpose : The purpose of this study is to compare the ability of spectral domain optical coherence tomography angiography (SD-OCTA) and indocyanine green angiography (ICGA) to detect and measure lesion area in patients with type 1 and 2 choroidal neovascularization (CNV). Methods : Types 1 and 2 neovascular AMD (nAMD) were included in this prospective and observational case series. ETDRS best-corrected visual acuity (BCVA), ophthalmic examination with funduscopy, OCTA (AngioVue), fluorescein angiography ...
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    4. Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye

      Compact akinetic swept source optical coherence tomography angiography at 1060 nm supporting a wide field of view and adaptive optics imaging modes of the posterior eye
      Imaging of the human retina with high resolution is an essential step towards improved diagnosis and treatment control. In this paper, we introduce a compact, clinically user-friendly instrument based on swept source optical coherence tomography (SS-OCT). A key feature of the system is the realization of two different operation modes. The first operation mode is similar to conventional OCT imaging and provides large field of view (FoV) images (up to ...
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    5. THREE-DIMENSIONAL ANALYSIS OF RETINAL MICROANEURYSMS WITH ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY

      THREE-DIMENSIONAL ANALYSIS OF RETINAL MICROANEURYSMS WITH ADAPTIVE OPTICS OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To characterize retinal microaneurysms (MAs) in patients with diabetes using adaptive optics optical coherence tomography (AOOCT) and compare details found in AOOCT with those found in commercially available retinal imaging techniques. Methods: Patients with diabetes and MA in the macular area were included in this pilot study. The area of interest, identified in standard fluorescein angiography, was imaged using an AO fundus camera and AOOCT. Microaneurysms were characterized in ...
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    6. Correlation between morphological characteristics in spectral-domain-optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy

      Correlation between morphological characteristics in spectral-domain-optical coherence tomography, different functional tests and a patient's subjective handicap in acute central serous chorioretinopathy
      ...est in any of the products and methods mentioned in this study. Bianca S. Gerendas is a consultant for Roche. Ursula Schmidt-Erfurth is a consultant for Novartis, Genentech, Bayer, Boehringer and Carl Zeiss Meditec....
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    7. IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY

      IMAGING OF VITELLIFORM MACULAR LESIONS USING POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To examine the involvement of the retinal pigment epithelium (RPE) in the presence of vitelliform macular lesions (VML) in Best vitelliform macular dystrophy (BVMD), autosomal recessive bestrophinopathy, and adult-onset vitelliform macular degeneration using polarization-sensitive optical coherence tomography (PS-OCT). Methods: A total of 35 eyes of 18 patients were imaged using a PS-OCT system and blue light fundus autofluorescence imaging. Pathogenic mutations in the BEST1 gene, 3 of which were ...
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    8. Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT on December 15th in Rome Italy which Already has over 1,000 Attendees.

      Register Now for the International Congress on OCT Angiography, "en face" OCT, and Advances in OCT  on December 15th in Rome Italy which Already has over 1,000 Attendees.
      ...Staurenghi, Nadia Waheed. Quan Dong Nguyen, SriniVas Sadda, Yves Cohen, Wolfgang Drexler, Joseph Carroll, and Ursula Schmidt Erfurth. The growing number of attendees (from 450 to 1450 in three years) shows that the meeti...
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    9. Predicting Macular Edema Recurrence from Spatio-Temporal Signatures in Optical Coherence Tomography Images

      Predicting Macular Edema Recurrence from Spatio-Temporal Signatures in Optical Coherence Tomography Images
      Prediction of treatment responses from available data is key to optimizing personalized treatment. Retinal diseases are treated over long periods and patients response patterns differ substantially, ranging from a complete response to a recurrence of the disease and need for re-treatment at different intervals. Linking observable variables in high-dimensional observations to outcome is challenging. In this paper, we present and evaluate two different data-driven machine learning approaches operating in a ...
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    10. Predicting Macular Edema Recurrence from Spatio-Temporal Signatures in Optical Coherence Tomography Image

      Predicting Macular Edema Recurrence from Spatio-Temporal Signatures in Optical Coherence Tomography Image
      Abstract: Prediction of treatment responses from available data is key to optimizing personalized treatment. Retinal diseases are treated over long periods and patients response patterns differ substantially, ranging from a complete response to a recurrence of the disease and need for re-treatment at different intervals. Linking observable variables in high-dimensional observations to outcome is challenging. In this paper, we present and evaluate two different data-driven machine learning approaches operating in ...
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    11. Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images

      Supervised learning and dimension reduction techniques for quantification of retinal fluid in optical coherence tomography images
      Purpose The purpose of the present study is to develop fast automated quantification of retinal fluid in optical coherence tomography (OCT) image sets. Methods We developed an image analysis pipeline tailored towards OCT images that consists of five steps for binary retinal fluid segmentation. The method is based on feature extraction, pre-segmention, dimension reduction procedures, and supervised learning tools. Results Fluid identification using our pipeline was tested on two separate ...
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    12. COMPARISON OF GANGLION CELL INNER PLEXIFORM LAYER THICKNESS BY CIRRUS AND SPECTRALIS OPTICAL COHERENCE TOMOGRAPHY IN DIABETIC MACULAR EDEMA

      COMPARISON OF GANGLION CELL INNER PLEXIFORM LAYER THICKNESS BY CIRRUS AND SPECTRALIS OPTICAL COHERENCE TOMOGRAPHY IN DIABETIC MACULAR EDEMA
      Purpose: Reduced thickness of the ganglion cell inner plexiform layer indicates diabetic neurodegeneration and can be assessed by spectral domain optical coherence tomography. The authors investigated the comparability of ganglion cell inner plexiform layer measurements from two spectral domain optical coherence tomography devices in patients with diabetic macular edema (DME). Methods: Analysis of optical coherence tomography data sets of eyes with and fellow eyes without DME. Macular cube scans of ...
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    13. Monitoring retinoschisis and non-acute retinal detachment by optical coherence tomography: morphologic aspects and clinical impact

      Monitoring retinoschisis and non-acute retinal detachment by optical coherence tomography: morphologic aspects and clinical impact
      Purpose To differentiate retinoschisis (RS) from non-acute retinal detachment (naRD) in clinical routine using optical coherence tomography (OCT), describe unique morphological OCT characteristics and monitor disease progression. Methods This prospective, observational study included 64 eyes of 44 patients with either RS or naRD. Patients were examined clinically and using Heidelberg Spectralis OCT , Topcon DRI OCT and Cirrus HRA-OCT over 2 years with follow-up at 1, 3, 6, 12 and 24 ...
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    14. Identification and clinical role of choroidal neovascularization characteristics based on optical coherence tomography angiography

      Identification and clinical role of choroidal neovascularization characteristics based on optical coherence tomography angiography
      Purpose To suggest a novel classification of neovascular age-related macular degeneration (AMD) based on optical coherence tomography angiography (OCTA) and to correlate morphological characteristics based on optical coherence tomography (OCT)/OCTA with clinical criteria of disease activity. Methods A total of 88 eyes with neovascular AMD (14 treatment-nave, 74 eyes following anti-vascular endothelial growth factor treatment (VEGF)) were examined using the AngioVue OCTA system (Optovue, Inc., Fremont, CA, USA) and ...
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    15. Reproducibility of Retinal Thickness Measurements across Spectral-Domain Optical Coherence Tomography Devices using Iowa Reference Algorithm

      Reproducibility of Retinal Thickness Measurements across Spectral-Domain Optical Coherence Tomography Devices using Iowa Reference Algorithm
      PURPOSE: Establishing and obtaining consistent quantitative indices of retinal thickness from a variety of clinically used Spectral-Domain Optical Coherence Tomography scanners. DESIGN: Retinal images from five Spectral-Domain Optical Coherence Tomography scanners were used to determine total retinal thickness with scanner-specific correction factors establishing consistency of thickness measurement across devices. PARTICIPANTS: 55 Fovea-centered Spectral-Domain Optical Coherence Tomography volumes from eleven subjects were analyzed, obtained from Cirrus HD-OCT, RS-3000, Heidelberg Spectralis, RTVue ...
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  2. About Ursula Schmidt-Erfurth

    Ursula Schmidt-Erfurth

    Ursula M. Schmidt-Erfurth is a Professor of Opththalmology at the Vienna Medical University, Austria.

  3. Quotes

    1. Around 2.5 million people every year develop macular degeneration and diabetes-related retinopathy worldwide...Before OCT, around 20 per cent of patients with this condition worldwide went blind; now, however, it is only two per cent.
      In 200 years of the eye clinic: diseases of the retina can be predicted