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2. Vasculature of a minipig eye (microCT Group, Institute of Anatomy, University of Bern)
  
  Explore YouTube Aug 12 2020 Ophthalmology
  
  ...MicroangioCT of a minipig eye (collaboration with Vetsuisse Faculty, University of Zurich and OCTlab Research Laboratory, Department of Ophthalmology, University of Basel). Contrast agent used: Angiofil (Fumedi...
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  Mentions: University of Zurich University of Bern
3. Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study
  
  Explore SAGE Journals Jul 3 2020 Ophthalmology
  
  Purpose: To report the characteristics of non-proliferative fellow eyes in patients with unilateral proliferative macular telangiectasia type 2 (MacTel). Methods: This was a multicenter, retrospective study and included fellow eyes of eyes with subretinal neovascular membrane (SRNVM). Multimodal imaging including fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) was performed. OCT and OCTA measurements included central macular thickness (CMT), subfoveal choroidal thickness (SFCT), foveal avascular zone (FAZ) area ...
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  Mentions: University of Pittsburgh L V Prasad Eye Institute University of Sydney
4. Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties
  
  Explore IOVS Journal Jun 19 2020 Ophthalmology
  
  Purpose : Quasi-static optical coherence elastography (OCE) is an emerging technology to investigate corneal biomechanical behavior in situations similar to physiological stress conditions. Herein OCE was applied to evaluate previously inaccessible biomechanical characteristics of human corneal tissue and to study the role of Bowman's layer in corneal biomechanics. Methods : Human corneal donor buttons ( n = 23) were obtained and Descemet's membrane and endothelium were removed. In 11 corneas, Bowman's ...
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  Mentions: University of Zurich University of Geneva
5. Spectral Domain Optical Coherence Tomography in Awake Rabbits Allows Identification of the Visual Streak, a Comparison with Histology
  
  Explore TVST Journal Apr 28 2020 Ophthalmology
  
  Purpose : To evaluate visual streak (VS) identification on spectral-domain optical coherence tomography (SD-OCT) scans in awake rabbits. To report thickness measurements in the VS and adjacent retina on OCT B-scans and histologic sections and to assess inter-method bias, precision and repeatability between OCT and histology. Methods : Vertical SD-OCT B-scan images through the optic nerve head and VS were acquired from 16 awake, ophthalmologically healthy experimental rabbits. Scans were acquired from ...
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  Mentions: University of Zurich
6. Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke. A Prospective Observational Study
  
  Explore Home - ClinicalTrials.gov Apr 27 2020 Ophthalmology , Clinical Trials
  
  Fundoscopy, optical coherence tomography (OCT) and OCT-angiography (OCTA) are established examinations and bear minimal risks. The recognition of retinal microvascular signs will enhance the pathophysiological understanding of the vasculopathy in patients with intracerebral haemorrhage (ICH) and aneurysmatic subarachnoid hemorrhage (aSAH) and might serve as prognostic and diagnostic indicators.
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  Mentions: University of Zurich
7. Optical coherence tomography of patients with Parkinson’s disease and progressive supranuclear palsy
  
  Explore ScienceDirect Dec 12 2019 Neurology , Ophthalmology
  
  Objectives To determine if Parkinsons disease (PD) and progressive supranuclear palsy (PSP) differed on retinal measurements using optical coherence tomography (OCT). Patients and methods In a prospective, controlled, cross-sectional cohort study, we recruited patients with PD or PSP for more than three years, as well as control subjects. We measured peripapillary retinal nerve fiber layer (RNFL) thickness and macular volume using spectral-domain OCT. The association between these OCT measures and ...
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  Mentions: University of British Columbia University Hospital Zurich University of Zurich
8. Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns
  
  Explore ScienceDirect Sep 14 2019 Ophthalmology
  
  Purpose To characterize the topographic relationships among vitreous structures including the premacular bursa, prevascular vitreous fissures, cisterns and lacunae in healthy subjects using en face and cross-sectional swept-source optical coherence tomography (SS-OCT). Design Prospective comparative study. Subjects Sixty eyes of 60 healthy subjects (age range = 4 35 years). Eyes of individuals younger than 20 years (n= 29) were compared with eyes of individuals aged 20 years or older (n=31 ...
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  Mentions: LuEsther T. Mertz Retinal Research Center University of Zurich K. Bailey Freund
9. Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography
  
  Explore IOVS Journal Aug 6 2019 Ophthalmology
  
  Purpose : The purpose of this study is to assess with spectral-domain optical coherence tomography (OCT) the interspecies variation of outer retinal morphology and identification of choriocapillaris in four research animal species. Methods : Spectralis HRA+OCT images acquired from locations dorsal, central, and ventral to the optic disc in healthy, anesthetized animals were evaluated by two independent readers. First, the number of OCT B-scans on which a choriocapillaris layer could clearly ...
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  Mentions: University of Zurich
10. Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction
  
  Explore Hindawi Publishing Corporation Jul 1 2019 Ophthalmology
  
  Multimodal imaging techniques were performed in a patient with a newly emerged visual field defect; a missing retinal lesion on fundus examination made the diagnosis challenging but infrared imaging showed a larger area of retinal abnormality temporal to the fovea. Indocyanine green angiography (IA) showed late hypofluorescence and there was mild hyperautofluorescence which is known from acute zonal occult outer retinopathy (AZOOR). Despite normal fluorescein angiography (FA) results, a perfusion ...
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  Mentions: University of Heidelberg Stephan Michels University of Zurich
11. Faster, wider, deeper: imaging advances in focus at Hot Topics session
  
  Explore Home: SPIE.org Feb 19 2019
  
  ...ding of brain function, [and the] diagnosis and treatment of neurological disorders," says Daniel Razansky of University of Zurich and ETH Zurich, one of the speakers at the BiOS Hot Topics session at SPIE Photonics West...
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  Mentions: Cornell University Yoshiaki Yasuno University of Tsukuba
12. Changes in Coronary Plaque Composition in Patients With Acute Myocardial Infarction Treated With High-Intensity Statin Therapy (IBIS-4): A Serial Optical Coherence Tomography Study
  
  Explore ScienceDirect Dec 19 2018 Cardiology
  
  Objectives This study assessed changes in optical coherence tomography (OCT)-defined plaque composition in patients with ST-elevation myocardial infarction (STEMI) receiving high-intensity statin treatment. Background OCT is a high-resolution modality capable of measuring plaque characteristics including fibrous cap thickness (FCT) and macrophage infiltration. There is limited in vivo evidence regarding the effects of statins on OCT-defined coronary atheroma composition and no evidence in the context of STEMI. Methods In the ...
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  Mentions: Imperial College London Leiden University University of Copenhagen
13. Optical coherence tomography as a means to characterize visual pathway involvement in multiple sclerosis
  
  Explore LWW Online Aug 7 2018 Neurology , Ophthalmology
  
  Purpose of review Optical coherence tomography (OCT) is a noninvasive in-vivo imaging tool that enables the quantification of the various retinal layer thicknesses. Given the frequent involvement of the visual pathway in multiple sclerosis , OCT has become an important tool in clinical practice, research and clinical trials. In this review, the role of OCT as a means to investigate visual pathway damage in multiple sclerosis is discussed. Recent findings Evidence ...
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  Mentions: University Hospital Zurich University of Zurich
14. THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY
  
  Explore LWW Online May 16 2017 Ophthalmology
  
  Purpose: To analyze submacular perforating scleral vessels (PSVs) using enhanced depth imaging spectral domain optical coherence tomography (EDI-SDOCT). Methods: Twenty-two eyes of 11 healthy women were included in this retrospective study. Central EDI-SDOCT scans (3 x 4.5 x 1.9 mm, 13.5 mm2 scan area) were acquired and postprocessed by denoising, manual sclera segmentation, and PSV investigated by five graders. Results: Mean age was 22.4 +/- 6.2 ...
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  Mentions: Johns Hopkins University University Hospital Zurich Hendrik P. N. Scholl
15. Optical Coherence Tomography and Magnetic Resonance Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
  
  Explore MDPI Open Access Journals Platform Nov 15 2016 Neurology , Ophthalmology
  
  Irreversible disability in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is largely attributed to neuronal and axonal degeneration, which, along with inflammation, is one of the major pathological hallmarks of these diseases. Optical coherence tomography (OCT) is a non-invasive imaging tool that has been used in MS, NMOSD, and other diseases to quantify damage to the retina, including the ganglion cells and their axons. The fact that these ...
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  Mentions: University Hospital Zurich University of Zurich
16. Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography
  
  Explore IOVS Journal Sep 14 2016 Ophthalmology
  
  Purpose : The purposes of this study were to describe choroidal findings observed using optical coherence tomography with enhanced depth imaging (EDI-OCT) in eyes with birdshot chorioretinitis (BSCR) and to test the hypothesis that these findings are related to participant demographics, clinical characteristics, and treatment. Methods : In a multicenter, cross-sectional study, 172 eyes of 86 individuals with BSCR underwent a standardized clinical evaluation, including defined protocols for EDI-OCT imaging, with macular ...
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  Mentions: Johns Hopkins University Duke University Northwestern University
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