1. University of Zurich

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    1. Mentioned In 45 Articles

    2. Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats

      Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats
      Purpose: To evaluate the outer retinal band thickness and choriocapillaris (CC) visibility in four distinct retinal regions in dogs and cats imaged with spectral domain optical coherence tomography (SD-OCT). To attempt delineation of a fovea-like region in canine and feline SD-OCT scans, aided by the identification of outer retinal thickness differences between retinal regions. Methods: Spectralis HRA + OCT SD-OCT scans from healthy, anesthetized dogs (n = 10) and cats (n = 12 ...
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    3. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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    4. Total Neuro-retinal Tubulation (TNT), a novel imaging finding

      Total Neuro-retinal Tubulation (TNT), a novel imaging finding
      A peculiar tubular structure was found in the left eye (LE) of a 71-year-old patient with diabetic retinopathy , who already had undergone panretinal-photocoagulation, detected by spectral-domain optical coherence tomography (SD-OCT) as an incidental finding . The reason for consultation was vitreous hemorrhage of the fellow-eye. Fundoscopic examination of LE revealed three oval retinal holes separated by small bridges of retinal tissue, which corresponded to tubular structures visible in SD-OCT, surrounded by ...
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    5. Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy

      Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy
      Background/aims To assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy. Design Observational study with retrospective analysis of data. Methods Participants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person ...
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    6. Globotrioasylsphingosine Levels and Optical Coherence Tomography Angiography in Fabry Disease Patients

      Globotrioasylsphingosine Levels and Optical Coherence Tomography Angiography in Fabry Disease Patients
      Background: To date, there are no studies associating the dried blood spot (DBS) levels of globotrioasylsphingosine (lysoGb3) with quantitative optical coherence tomography angiography (OCTA) parameters in Fabry disease (FD) patients. Here, we aimed to investigate the association between OCTA vessel density (VD), vessel length density (VLD) with DBS lysoGb3. Methods: A retrospective, single center analysis of all consecutive FD patients enrolled at the Department of Ophthalmology of the University Hospital ...
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    7. Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study

      Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study
      Purpose: To report the characteristics of non-proliferative fellow eyes in patients with unilateral proliferative macular telangiectasia type 2 (MacTel). Methods: This was a multicenter, retrospective study and included fellow eyes of eyes with subretinal neovascular membrane (SRNVM). Multimodal imaging including fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) was performed. OCT and OCTA measurements included central macular thickness (CMT), subfoveal choroidal thickness (SFCT), foveal avascular zone (FAZ) area ...
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    8. Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties

      Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties
      Purpose : Quasi-static optical coherence elastography (OCE) is an emerging technology to investigate corneal biomechanical behavior in situations similar to physiological stress conditions. Herein OCE was applied to evaluate previously inaccessible biomechanical characteristics of human corneal tissue and to study the role of Bowman's layer in corneal biomechanics. Methods : Human corneal donor buttons ( n = 23) were obtained and Descemet's membrane and endothelium were removed. In 11 corneas, Bowman's ...
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    9. Spectral Domain Optical Coherence Tomography in Awake Rabbits Allows Identification of the Visual Streak, a Comparison with Histology

      Spectral Domain Optical Coherence Tomography in Awake Rabbits Allows Identification of the Visual Streak, a Comparison with Histology
      Purpose : To evaluate visual streak (VS) identification on spectral-domain optical coherence tomography (SD-OCT) scans in awake rabbits. To report thickness measurements in the VS and adjacent retina on OCT B-scans and histologic sections and to assess inter-method bias, precision and repeatability between OCT and histology. Methods : Vertical SD-OCT B-scan images through the optic nerve head and VS were acquired from 16 awake, ophthalmologically healthy experimental rabbits. Scans were acquired from ...
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    10. Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke. A Prospective Observational Study

      Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke. A Prospective Observational Study
      Fundoscopy, optical coherence tomography (OCT) and OCT-angiography (OCTA) are established examinations and bear minimal risks. The recognition of retinal microvascular signs will enhance the pathophysiological understanding of the vasculopathy in patients with intracerebral haemorrhage (ICH) and aneurysmatic subarachnoid hemorrhage (aSAH) and might serve as prognostic and diagnostic indicators.
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    11. Optical coherence tomography of patients with Parkinson’s disease and progressive supranuclear palsy

      Optical coherence tomography of patients with Parkinson’s disease and progressive supranuclear palsy
      Objectives To determine if Parkinsons disease (PD) and progressive supranuclear palsy (PSP) differed on retinal measurements using optical coherence tomography (OCT). Patients and methods In a prospective, controlled, cross-sectional cohort study, we recruited patients with PD or PSP for more than three years, as well as control subjects. We measured peripapillary retinal nerve fiber layer (RNFL) thickness and macular volume using spectral-domain OCT. The association between these OCT measures and ...
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    12. Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns

      Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns
      Purpose To characterize the topographic relationships among vitreous structures including the premacular bursa, prevascular vitreous fissures, cisterns and lacunae in healthy subjects using en face and cross-sectional swept-source optical coherence tomography (SS-OCT). Design Prospective comparative study. Subjects Sixty eyes of 60 healthy subjects (age range = 4 35 years). Eyes of individuals younger than 20 years (n= 29) were compared with eyes of individuals aged 20 years or older (n=31 ...
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    13. Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography

      Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography
      Purpose : The purpose of this study is to assess with spectral-domain optical coherence tomography (OCT) the interspecies variation of outer retinal morphology and identification of choriocapillaris in four research animal species. Methods : Spectralis HRA+OCT images acquired from locations dorsal, central, and ventral to the optic disc in healthy, anesthetized animals were evaluated by two independent readers. First, the number of OCT B-scans on which a choriocapillaris layer could clearly ...
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    14. Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction

      Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction
      Multimodal imaging techniques were performed in a patient with a newly emerged visual field defect; a missing retinal lesion on fundus examination made the diagnosis challenging but infrared imaging showed a larger area of retinal abnormality temporal to the fovea. Indocyanine green angiography (IA) showed late hypofluorescence and there was mild hyperautofluorescence which is known from acute zonal occult outer retinopathy (AZOOR). Despite normal fluorescein angiography (FA) results, a perfusion ...
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  2. About University of Zurich

    University of Zurich

    University of Zurich (Universität Zürich) is the largest university of Switzerland, in the city of Zürich. It was founded on April 29, 1833 with faculties of theology, law, medicine and philosophy. Currently, the University has faculties of arts, economics, law, medicine, science, theology and veterinary medicine. University Hosptial Zurich is a teaching hosptical associated with the University of Zurich.