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2. Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats
  
  Explore Wiley Online Library May 30 2022 Ophthalmology
  
  Purpose: To evaluate the outer retinal band thickness and choriocapillaris (CC) visibility in four distinct retinal regions in dogs and cats imaged with spectral domain optical coherence tomography (SD-OCT). To attempt delineation of a fovea-like region in canine and feline SD-OCT scans, aided by the identification of outer retinal thickness differences between retinal regions. Methods: Spectralis HRA + OCT SD-OCT scans from healthy, anesthetized dogs (n = 10) and cats (n = 12 ...
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  Mentions: University of Zurich
3. Optical coherence tomography in coronary atherosclerosis assessment and intervention
  
  Explore Nature Publishing Group Apr 30 2022 Cardiology
  
  Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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  Mentions: Brigham and Women’s Hospital Johns Hopkins University Massachusetts Institute of Technology
4. Total Neuro-retinal Tubulation (TNT), a novel imaging finding
  
  Explore ScienceDirect Feb 7 2022 Ophthalmology
  
  A peculiar tubular structure was found in the left eye (LE) of a 71-year-old patient with diabetic retinopathy , who already had undergone panretinal-photocoagulation, detected by spectral-domain optical coherence tomography (SD-OCT) as an incidental finding . The reason for consultation was vitreous hemorrhage of the fellow-eye. Fundoscopic examination of LE revealed three oval retinal holes separated by small bridges of retinal tissue, which corresponded to tubular structures visible in SD-OCT, surrounded by ...
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  Mentions: Carl Zeiss Meditec University of Zurich
5. Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy
  
  Explore BMJ Health & Care Informatics May 26 2021 Ophthalmology
  
  Background/aims To assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy. Design Observational study with retrospective analysis of data. Methods Participants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person ...
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  Mentions: University College London University of Zurich
6. Globotrioasylsphingosine Levels and Optical Coherence Tomography Angiography in Fabry Disease Patients
  
  Explore MDPI Open Access Journals Platform Mar 11 2021 Ophthalmology
  
  Background: To date, there are no studies associating the dried blood spot (DBS) levels of globotrioasylsphingosine (lysoGb3) with quantitative optical coherence tomography angiography (OCTA) parameters in Fabry disease (FD) patients. Here, we aimed to investigate the association between OCTA vessel density (VD), vessel length density (VLD) with DBS lysoGb3. Methods: A retrospective, single center analysis of all consecutive FD patients enrolled at the Department of Ophthalmology of the University Hospital ...
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  Mentions: University of Zurich
7. Vasculature of a minipig eye (microCT Group, Institute of Anatomy, University of Bern)
  
  Explore YouTube Aug 12 2020 Ophthalmology
  
  ...MicroangioCT of a minipig eye (collaboration with Vetsuisse Faculty, University of Zurich and OCTlab Research Laboratory, Department of Ophthalmology, University of Basel). Contrast agent used: Angiofil (Fumedi...
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  Mentions: University of Zurich University of Bern
8. Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study
  
  Explore SAGE Journals Jul 3 2020 Ophthalmology
  
  Purpose: To report the characteristics of non-proliferative fellow eyes in patients with unilateral proliferative macular telangiectasia type 2 (MacTel). Methods: This was a multicenter, retrospective study and included fellow eyes of eyes with subretinal neovascular membrane (SRNVM). Multimodal imaging including fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) was performed. OCT and OCTA measurements included central macular thickness (CMT), subfoveal choroidal thickness (SFCT), foveal avascular zone (FAZ) area ...
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  Mentions: University of Pittsburgh L V Prasad Eye Institute University of Sydney
9. Quasi-Static Optical Coherence Elastography to Characterize Human Corneal Biomechanical Properties
  
  Explore IOVS Journal Jun 19 2020 Ophthalmology
  
  Purpose : Quasi-static optical coherence elastography (OCE) is an emerging technology to investigate corneal biomechanical behavior in situations similar to physiological stress conditions. Herein OCE was applied to evaluate previously inaccessible biomechanical characteristics of human corneal tissue and to study the role of Bowman's layer in corneal biomechanics. Methods : Human corneal donor buttons ( n = 23) were obtained and Descemet's membrane and endothelium were removed. In 11 corneas, Bowman's ...
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  Mentions: University of Zurich University of Geneva
10. Spectral Domain Optical Coherence Tomography in Awake Rabbits Allows Identification of the Visual Streak, a Comparison with Histology
  
  Explore TVST Journal Apr 28 2020 Ophthalmology
  
  Purpose : To evaluate visual streak (VS) identification on spectral-domain optical coherence tomography (SD-OCT) scans in awake rabbits. To report thickness measurements in the VS and adjacent retina on OCT B-scans and histologic sections and to assess inter-method bias, precision and repeatability between OCT and histology. Methods : Vertical SD-OCT B-scan images through the optic nerve head and VS were acquired from 16 awake, ophthalmologically healthy experimental rabbits. Scans were acquired from ...
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  Mentions: University of Zurich
11. Insights From the Retina on Cerebral Microvascular Dysfunction in Haemorrhagic Stroke. A Prospective Observational Study
  
  Explore Home - ClinicalTrials.gov Apr 27 2020 Ophthalmology , Clinical Trials
  
  Fundoscopy, optical coherence tomography (OCT) and OCT-angiography (OCTA) are established examinations and bear minimal risks. The recognition of retinal microvascular signs will enhance the pathophysiological understanding of the vasculopathy in patients with intracerebral haemorrhage (ICH) and aneurysmatic subarachnoid hemorrhage (aSAH) and might serve as prognostic and diagnostic indicators.
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  Mentions: University of Zurich
12. Optical coherence tomography of patients with Parkinson’s disease and progressive supranuclear palsy
  
  Explore ScienceDirect Dec 12 2019 Neurology , Ophthalmology
  
  Objectives To determine if Parkinsons disease (PD) and progressive supranuclear palsy (PSP) differed on retinal measurements using optical coherence tomography (OCT). Patients and methods In a prospective, controlled, cross-sectional cohort study, we recruited patients with PD or PSP for more than three years, as well as control subjects. We measured peripapillary retinal nerve fiber layer (RNFL) thickness and macular volume using spectral-domain OCT. The association between these OCT measures and ...
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  Mentions: University of British Columbia University Hospital Zurich University of Zurich
13. Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns
  
  Explore ScienceDirect Sep 14 2019 Ophthalmology
  
  Purpose To characterize the topographic relationships among vitreous structures including the premacular bursa, prevascular vitreous fissures, cisterns and lacunae in healthy subjects using en face and cross-sectional swept-source optical coherence tomography (SS-OCT). Design Prospective comparative study. Subjects Sixty eyes of 60 healthy subjects (age range = 4 35 years). Eyes of individuals younger than 20 years (n= 29) were compared with eyes of individuals aged 20 years or older (n=31 ...
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  Mentions: LuEsther T. Mertz Retinal Research Center University of Zurich
14. Interspecies Variation of Outer Retina and Choriocapillaris Imaged With Optical Coherence Tomography
  
  Explore IOVS Journal Aug 6 2019 Ophthalmology
  
  Purpose : The purpose of this study is to assess with spectral-domain optical coherence tomography (OCT) the interspecies variation of outer retinal morphology and identification of choriocapillaris in four research animal species. Methods : Spectralis HRA+OCT images acquired from locations dorsal, central, and ventral to the optic disc in healthy, anesthetized animals were evaluated by two independent readers. First, the number of OCT B-scans on which a choriocapillaris layer could clearly ...
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  Mentions: University of Zurich
15. Optical Coherence Tomography Angiography (OCT-A) in a Patient with Occult Retinal Dysfunction
  
  Explore Hindawi Publishing Corporation Jul 1 2019 Ophthalmology
  
  Multimodal imaging techniques were performed in a patient with a newly emerged visual field defect; a missing retinal lesion on fundus examination made the diagnosis challenging but infrared imaging showed a larger area of retinal abnormality temporal to the fovea. Indocyanine green angiography (IA) showed late hypofluorescence and there was mild hyperautofluorescence which is known from acute zonal occult outer retinopathy (AZOOR). Despite normal fluorescein angiography (FA) results, a perfusion ...
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  Mentions: University of Heidelberg University of Zurich
16. Faster, wider, deeper: imaging advances in focus at Hot Topics session
  
  Explore Home: SPIE.org Feb 19 2019
  
  ...ding of brain function, [and the] diagnosis and treatment of neurological disorders," says Daniel Razansky of University of Zurich and ETH Zurich, one of the speakers at the BiOS Hot Topics session at SPIE Photonics West...
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  Mentions: Cornell University University of Tsukuba University of Zurich
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