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    1. Mentioned In 136 Articles

    2. Comparing Retinal Structure in Patients with Achromatopsia and Blue Cone Monochromacy Using OCT

      Comparing Retinal Structure in Patients with Achromatopsia and Blue Cone Monochromacy Using OCT
      Purpose: To compare foveal hypoplasia and the appearance of the ellipsoid zone (EZ) at the fovea in patients with genetically confirmed achromatopsia (ACHM) and blue cone monochromacy (BCM). Design: Retrospective, multi-center observational study. Subjects: Molecularly confirmed patients with ACHM (n = 89) and BCM (n = 33). Methods: We analyzed high-resolution spectral domain optical coherence tomography (SD-OCT) images of the macula from aforementioned patients with BCM. Three observers independently graded SD-OCT images ...
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    3. Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data

      Automated classification of otitis media with OCT: augmenting pediatric image datasets with gold-standard animal model data
      Otitis media (OM) is an extremely common disease that affects children worldwide. Optical coherence tomography (OCT) has emerged as a noninvasive diagnostic tool for OM, which can detect the presence and quantify the properties of middle ear fluid and biofilms. Here, the use of OCT data from the chinchilla, the gold-standard OM model for the human disease, is used to supplement a human image database to produce diagnostically relevant conclusions ...
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    4. Coherent Optical Detection of Middle Ear Disease

      Coherent Optical Detection of Middle Ear Disease
      Otitis media (OM) is the most common diagnosis in pediatric patients seen for illness in the United States, affects 90% of all children, and is the most common indication for antimicrobial therapy and surgery in young children. Despite many attempts to improve diagnosis, treatment, and prevention, OM continues its highly prevalent impact on children and substantial ongoing morbidity. OM continues as the most common cause of hearing loss in children ...
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    5. Redefining the Spectrum of Pentosan Polysulfate Retinopathy: Multimodal Imaging Findings from a Cross-Sectional Screening Study

      Redefining the Spectrum of Pentosan Polysulfate Retinopathy: Multimodal Imaging Findings from a Cross-Sectional Screening Study
      Purpose: There is growing evidence of a direct association between Pentosan polysulfate (PPS) therapy and the development of macular changes. Using standardized visual acuity testing and multimodal imaging, we investigate the impact on vision and describe an expanded spectrum of imaging findings among PPS users. Design: Cross-sectional screening study. Participants: Thirty-nine patients who were current or recent users of PPS. Methods: Participants underwent a brief eye exam and answered a ...
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    6. Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts

      Recommendations for OCTA reporting in retinal vascular disease: A Delphi approach by International Experts
      Purpose: To develop a consensus nomenclature for reporting optical coherence tomography angiography (OCTA) findings in retinal vascular disease (e.g., diabetic retinopathy, retinal vein occlusion) by international experts. Design: Delphi-based survey SUBJECTS, PARTICIPANTS AND/OR CONTROLS: Twenty-five retinal vascular disease and OCTA imaging experts METHODS, INTERVENTION, OR TESTING: A Delphi method of consensus development was used, comprising two rounds of online questionnaires, followed by a face-to-face meeting conducted virtually. Twenty-five ...
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    7. Medical College of Wisconsin Receives 2022 NIH Grant for Otitis Media Diagnosis and Treatment

      Medical College of Wisconsin Receives 2022 NIH Grant for Otitis Media Diagnosis and Treatment
      Medical College of Wisconsin received a 2022 NIH Grant for $576,383 for Otitis Media Diagnosis and Treatment. The principal investigator is Joseph Kerchner. Below is a summary of the proposed work. Otitis media (OM) is the most common diagnosis in pediatric patients seen for illness in the United States (1,2), affects 90% of all children (3,4) and is the most common indication for antimicrobial therapy and surgery ...
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    8. Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography

      Challenges Associated With Ellipsoid Zone Intensity Measurements Using Optical Coherence Tomography
      Optical coherence tomography (OCT) allows noninvasive visualization of individual retinal layers and has become a mainstay in the diagnosis and management of a wide range of retinal and systemic diseases. As the number of available treatments increases, there is growing interest in developing sensitive OCT-based biomarkers for assessing therapeutic response. In particular, the hyperreflective outer retinal band just posterior to the external limiting membrane, also known as the ellipsoid zone ...
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    9. Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel

      Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel
      Purpose: To assess the performance of two spectral-domain optical coherence tomography-angiography systems in a natural model of hypoperfusion: the hibernating thirteen-lined ground squirrel (13-LGS). Methods: Using a high-speed (130 kHz) OCT-A system (HS-OCT-A) and a commercial OCT (36 kHz; Bioptigen Envisu; BE-OCT-A), we imaged the 13-LGS retina throughout its hibernation cycle. Custom software was used to extract the superior, middle, and deep capillary plexus (SCP, MCP, and DCP, respectively). The ...
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    10. Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography

      Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography
      Patient-derived cancer organoids (PCOs) are in vitro organotypic models that reflect in vivo drug response, thus PCOs are an accessible model for cancer drug screening in a clinically relevant timeframe. However, current methods to assess the response of PCOs are limited. Here, a custom swept-source optical coherence tomography (OCT) system was used to rapidly evaluate volumetric growth and drug response in PCOs. This system was optimized for an inverted imaging ...
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    11. Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.

      Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.
      Medical College of Wisconsin Receives a 2021 NIH Grant for $390,398 for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography. The principal investigator is Iris Kassem. Below is a summary of the proposed work. The Medical College of Wisconsin prioritizes research as one of its missions and includes in its strategic plan accelerating discovery with cutting-edge, evidence-based research. With this support we request funds for the shared instrumentation of a ...
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    12. OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6

      OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6
      Objective: To determine the inter-reader agreement for incomplete and complete retinal pigment epithelium and outer retinal atrophy (iRORA and cRORA respectively) and their related features in age-related macular degeneration (AMD). Design: Inter-reader agreement study. Participants: Twelve readers from six reading centers. Methods: Following formal training, readers qualitatively assessed 60 optical coherence tomography (OCT) B-scans from 60 eyes with AMD for nine individual features associated with early atrophy and performed seven ...
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    13. Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia

      Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia
      Purpose : To determine whether artifacts in optical coherence tomography (OCT) images are associated with the success or failure of adaptive optics scanning light ophthalmoscopy (AOSLO) imaging in subjects with achromatopsia (ACHM). Methods : Previously acquired OCT and non-confocal, split-detector AOSLO images from one eye of 66 subjects with genetically confirmed achromatopsia (15 CNGA3 and 51 CNGB3 ) were reviewed along with best-corrected visual acuity (BCVA) and axial length. OCT artifacts in interpolated ...
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  2. About University of Wisconsin

    University of Wisconsin

    University of Wisconsin System has established itself as one of the world's premier public university systems. The UW educates more than 173,000 students on 26 campuses, and serves more than one million citizens through statewide extension programs. The UW System's campuses in Madison and Milwaukee offer both undergraduate and graduate degree programs, including doctoral and professional programs. Eleven comprehensive campuses provide students both undergraduate and master's degree programs in smaller, more individualized academic settings. The UW System's 13 UW Colleges deliver freshman-sophomore courses for students seeking a foundation for a bachelor's degree.