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    1. Mentioned In 128 Articles

    2. Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel

      Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel
      Purpose: To assess the performance of two spectral-domain optical coherence tomography-angiography systems in a natural model of hypoperfusion: the hibernating thirteen-lined ground squirrel (13-LGS). Methods: Using a high-speed (130 kHz) OCT-A system (HS-OCT-A) and a commercial OCT (36 kHz; Bioptigen Envisu; BE-OCT-A), we imaged the 13-LGS retina throughout its hibernation cycle. Custom software was used to extract the superior, middle, and deep capillary plexus (SCP, MCP, and DCP, respectively). The ...
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    3. Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography

      Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography
      Patient-derived cancer organoids (PCOs) are in vitro organotypic models that reflect in vivo drug response, thus PCOs are an accessible model for cancer drug screening in a clinically relevant timeframe. However, current methods to assess the response of PCOs are limited. Here, a custom swept-source optical coherence tomography (OCT) system was used to rapidly evaluate volumetric growth and drug response in PCOs. This system was optimized for an inverted imaging ...
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    4. Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.

      Medical College of Wisconsin Receives NIH Grant for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography.
      Medical College of Wisconsin Receives a 2021 NIH Grant for $390,398 for Ophthalmic Microscope with Intraoperative Optical Coherence Tomography. The principal investigator is Iris Kassem. Below is a summary of the proposed work. The Medical College of Wisconsin prioritizes research as one of its missions and includes in its strategic plan accelerating discovery with cutting-edge, evidence-based research. With this support we request funds for the shared instrumentation of a ...
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    5. Optical Coherence Tomography Signs of Early Atrophy in Age-related Macular Degeneration: Inter-Reader Agreement. CAM Report 6

      Optical Coherence Tomography Signs of Early Atrophy in Age-related Macular Degeneration: Inter-Reader Agreement. CAM Report 6
      Objective: To determine the inter-reader agreement for incomplete and complete retinal pigment epithelium and outer retinal atrophy (iRORA and cRORA respectively) and their related features in age-related macular degeneration (AMD). Design: Inter-reader agreement study. Participants: Twelve readers from six reading centers. Methods: Following formal training, readers qualitatively assessed 60 optical coherence tomography (OCT) B-scans from 60 eyes with AMD for nine individual features associated with early atrophy and performed seven ...
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    6. Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia

      Optical Coherence Tomography Artifacts Are Associated With Adaptive Optics Scanning Light Ophthalmoscopy Success in Achromatopsia
      Purpose : To determine whether artifacts in optical coherence tomography (OCT) images are associated with the success or failure of adaptive optics scanning light ophthalmoscopy (AOSLO) imaging in subjects with achromatopsia (ACHM). Methods : Previously acquired OCT and non-confocal, split-detector AOSLO images from one eye of 66 subjects with genetically confirmed achromatopsia (15 CNGA3 and 51 CNGB3 ) were reviewed along with best-corrected visual acuity (BCVA) and axial length. OCT artifacts in interpolated ...
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    7. Spectral Domain Optical Coherence Tomography Predictors of Visual Acuity in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2)

      Spectral Domain Optical Coherence Tomography Predictors of Visual Acuity in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2)
      Objective To evaluate the association between baseline demographic and SD-OCT features with visual acuity (VA) in the S tudy of CO mparative Treatments for RE tinal Vein Occlusion 2 (SCORE2) over 2 years. Design Post- hoc analysis of prospective clinical trial data. Participants 362 SCORE2 participants with macular edema secondary to central retinal (CRVO) or hemi-retinal vein occlusion (HRVO). Methods SD-OCT volume scans were assessed at the SCORE2 reading center ...
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    8. Autoimmune retinopathy: findings and limitations from optical coherence tomography angiography

      Autoimmune retinopathy: findings and limitations from optical coherence tomography angiography
      Background and objective To report novel findings and limitations from optical coherence tomography angiography (OCTA) in the evaluation of autoimmune retinopathy (AIR). Study design We retrospectively reviewed features of five patients diagnosed with AIR and five controls. OCTA scans were obtained and manually segmented to provide accurate measurements of foveal avascular zone (FAZ), vessel density, and retinal thickness at different levels. Results The total retina and superficial vessel density throughout ...
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    9. Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics

      Assessing the Influence of OCT-A Device and Scan Size on Retinal Vascular Metrics
      Purpose : The purpose of this study was to investigate the effect of device and scan size on quantitative optical coherence tomography angiography (OCT-A) metrics. Methods : The 3 3 mm scans from Optovue AngioVue and Zeiss AngioPlex systems were included for 18 eyes of 18 subjects without ocular pathology. The foveal avascular zone (FAZ) was segmented manually by two observers, from which estimates of FAZ area (using both the nominal image ...
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    10. Medical College of Wisconsin Receives NIH Grant for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae

      Medical College of Wisconsin Receives NIH Grant for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae
      Medical College of Wisconsin Receives a 2020 NIH Grant for $486,444 for Assessing Photoreceptor Structure and Function in Normal and Diseased Retinae. The principal investigator is Joseph Carroll. Below is a summary of the proposed work. Inherited retinal degenerations affect approximately 1 in 1,500 individuals in the US, and given the extreme genotypic and phenotypic heterogeneity, the prospect of treating these devastating diseases is a formidable task. Nevertheless ...
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    11. Quantification of Geographic Atrophy using Spectral Domain Optical Coherence Tomography in Age-Related Macular Degeneration

      Quantification of Geographic Atrophy using Spectral Domain Optical Coherence Tomography in Age-Related Macular Degeneration
      Purpose To compare geographic atrophy (GA) area and enlargement rate measured with SD OCT to fundus autofluorescence (FAF), color fundus photography (CFP), and infrared reflectance (IR) imaging. Design; Retrospective, multicenter, natural history case series. Participants 70 eyes with GA from 48 participants were included. Methods Participants underwent SD OCT, FAF, CFP, and IR imaging at baseline and 12 months in the study eye. SD OCT images were graded for GA ...
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    12. Retinal specialist versus artificial intelligence detection of retinal fluid from optical coherence tomography: AREDS2 10-year Follow-On

      Retinal specialist versus artificial intelligence detection of retinal fluid from optical coherence tomography: AREDS2 10-year Follow-On
      Purpose To evaluate the performance of retinal specialists in detecting retinal fluid presence in spectral domain optical coherence tomography (SD-OCT) macular volume scans from eyes with age-related macular degeneration (AMD), and to compare performance with the artificial intelligence (AI)-based Notal OCT Analyzer (NOA). Design Prospective comparison of retinal fluid grades from human retinal specialists and the NOA on SD-OCT scans from two commonly used devices (Cirrus and Spectralis). Participants ...
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    13. Double diversity optical coherence tomography

      Double diversity optical coherence tomography
      This article provides theoretical analysis for a new generation of optical coherence tomography (OCT) scanners to overcome some main limitations of the technology. In the new design, exposure and detection are not limited to plane-waves that enter or reflect back from the sample exclusively orthogonally. Instead, the sample is scanned by more complex radiation patterns such as spherical or partially spherical light waves. Images that are generated based on this ...
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    14. Imaging of Macrophage-Like Cells in Living Human Retina Using Clinical OCT

      Imaging of Macrophage-Like Cells in Living Human Retina Using Clinical OCT
      Purpose : To image retinal macrophages at the vitreoretinal interface in the living human retina using a clinical optical coherence tomography (OCT) device. Methods : Eighteen healthy controls and three patients with retinopathies were imaged using a clinical spectral-domain OCT. In controls, 10 sequential scans were collected at three different locations: (1) 9 degrees temporal to the fovea, (2) the macula, and (3) the optic nerve head (ONH). Intervisit repeatability was evaluated ...
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  2. About University of Wisconsin

    University of Wisconsin

    University of Wisconsin System has established itself as one of the world's premier public university systems. The UW educates more than 173,000 students on 26 campuses, and serves more than one million citizens through statewide extension programs. The UW System's campuses in Madison and Milwaukee offer both undergraduate and graduate degree programs, including doctoral and professional programs. Eleven comprehensive campuses provide students both undergraduate and master's degree programs in smaller, more individualized academic settings. The UW System's 13 UW Colleges deliver freshman-sophomore courses for students seeking a foundation for a bachelor's degree.