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    1. Mentioned In 88 Articles

    2. INTRAOPERATIVE IMAGING OF RETAINED PERFLUOROCARBON LIQUID USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY

      INTRAOPERATIVE IMAGING OF RETAINED PERFLUOROCARBON LIQUID USING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To report images of retained perfluorocarbon liquid (PFCL) on the surface of the retina obtained during an intraoperative use of hand-held spectral domain optical coherence tomography. Methods: A 54-year-old man underwent pars plana vitrectomy with injection of PFCL to repair retinal detachment. Postoperatively, visually significant PFCL droplets were found to be retained in the eye. During the surgical removal of PFCL, a hand-held spectral domain optical coherence tomography was ...
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    3. Assessing the Accuracy of Foveal Avascular Zone Measurements Using Optical Coherence Tomography Angiography: Segmentation and Scaling

      Assessing the Accuracy of Foveal Avascular Zone Measurements Using Optical Coherence Tomography Angiography: Segmentation and Scaling
      Purpose : The foveal avascular zone (FAZ) is altered in numerous diseases. We assessed factors (axial length, segmentation method, age, sex) impacting FAZ measurements from optical coherence tomography (OCT) angiography images. Methods : We recruited 116 Caucasian subjects without ocular disease, and acquired two 3 3 mm AngioVue scans per each right eye (232 total scans). In images of the superficial plexus, the FAZ was segmented using the AngioVue semiautomatic nonflow measurement ...
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    4. Blood capillaries and vessels segmentation in optical coherence tomography angiogram using fuzzy C-means and Curvelet transform

      Blood capillaries and vessels segmentation in optical coherence tomography angiogram using fuzzy C-means and Curvelet transform
      Blood capillaries density and vessels structure in vivo brain provide information about diseases and hemodynamic in the brain network. Capillary density in animal brain is one of the indexes that determines if it has diabetes. Capillary density in the animal brain subjected to diabetes diminishes over time. Variation in physical structure and diameter of the vessels as a function of time gives us information about hemodynamic in the brain network ...
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    5. Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity

      Simultaneous Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Correlate Retinal Thickness Changes to Vascular Abnormalities in an In Vivo Mouse Model of Retinopathy of Prematurity
      Background . Retinopathy of prematurity (ROP) is a condition of abnormal retinal vascular development (RVD) in premature infants. Fluorescein angiography (FA) has depicted phases (early, mid, late, and mature) of RVD in oxygen-induced retinopathy (OIR) mice. We sought to establish the relationship between retinal structural and vascular changes using simultaneous FA and spectral domain optical coherence tomography (SD-OCT). Method . 63 mice were exposed to 77% oxygen at postnatal day 7 (P7 ...
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    6. The University of Wisconsin-Madison Receives Grant for Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases

      The University of Wisconsin-Madison Receives  Grant for  Epidemiology of Age-Related Macular Degeneration and Other Retinal Diseases
      ...of AMD independent of age, smoking status, and high-risk genetic markers.

      The University of Wisconsin-Madison Receives a 2017 NIH Grant for $768,348 for Epidemiology of Age-Related Macular...

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    7. University of Wisconsin-Madison Receives NIH Grant for Epidemiology of Age-Related Macular Degeneration and Other retinal diseases -Enrollment Center

      University of Wisconsin-Madison Receives NIH Grant  for Epidemiology of Age-Related Macular Degeneration and Other retinal diseases -Enrollment Center
      ...sis of AMD independent of age, smoking status, and high-risk genetic markers.

      University of Wisconsin-Madison Receives a 2017 NIH Grant for $149,848 for Epidemiology of Age-Related Macular...

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    8. The Effect of Retinal Melanin on Optical Coherence Tomography Images

      The Effect of Retinal Melanin on Optical Coherence Tomography Images
      Purpose : We assessed the effect of melanin on the appearance of hyperreflective outer retinal bands in optical coherence tomography (OCT) images. Methods : A total of 23 normal subjects and 51 patients with albinism were imaged using the Bioptigen high-resolution spectral-domain OCT. In addition, three wild type, three albino ( slc45a2 b4/b4 ), and eight tyrosinase mosaic zebrafish were imaged with the hand-held Bioptigen Envisu R2200 OCT. To identify pigmented versus nonpigmented ...
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    9. Involuntary Eye Motion Correction in Retinal Optical Coherence Tomography: Hardware or Software Solution?

      Involuntary Eye Motion Correction in Retinal Optical Coherence Tomography: Hardware or Software Solution?
      In this paper, we review state-of-the-art techniques to correct eye motion artifacts in Optical Coherence Tomography (OCT) imaging. The methods for eye motion artifact reduction can be categorized into two major classes: 1) hardware-based techniques and 2) software-based techniques. In the first class, additional hardware is mounted onto the OCT scanner to gather information about the eye motion patterns during OCT data acquisition. This information is later processed and applied ...
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    10. Imaging the adult zebrafish cone mosaic using optical coherence tomography

      Imaging the adult zebrafish cone mosaic using optical coherence tomography
      Zebrafish ( Danio rerio ) provide many advantages as a model organism for studying ocular disease and development, and there is great interest in the ability to non-invasively assess their photoreceptor mosaic. Despite recent applications of scanning light ophthalmoscopy, fundus photography, and gonioscopy to in vivo imaging of the adult zebrafish eye, current techniques either lack accurate scaling information (limiting quantitative analyses) or require euthanizing the fish (precluding longitudinal analyses). Here we ...
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    11. Directional optical coherence tomography systems and methods

      Directional optical coherence tomography systems and methods
      An optical coherence tomography system that includes an optical device having an adjustable optical element configured to displace a pupil entry point of light is provided. Optical coherence tomography methods using the optical coherence tomography system are also provided. The subject optical coherence tomography systems and methods find use in a variety of different applications, including imaging applications.
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    12. Variability in Spectral-Domain Optical Coherence Tomography over 4 Weeks by Age

      Variability in Spectral-Domain Optical Coherence Tomography over 4 Weeks by Age
      Purpose: To quantify variation in spectral-domain optical coherence tomography (SD-OCT) measures of total retinal thickness (top of inner limiting membrane to top of retinal pigment epithelium, RPE) and RPE thickness measures over a 4-week period and by age. Methods: A total of 76 volunteers aged 4085 years were seen at three visits over 4 weeks. Two Topcon SD-OCT scans were taken at each visit. Following grid re-centration, total retinal and ...
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    13. Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics

      Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics
      We analyzed heart wall motion and blood flow dynamics in chicken embryos using in vivo optical coherence tomography (OCT) imaging and computational fluid dynamics (CFD) embryo-specific modeling. We focused on the heart outflow tract (OFT) region of day 3 embryos, and compared normal (control) conditions to conditions after performing an OFT banding intervention, which alters hemodynamics in the embryonic heart and vasculature. We found that hemodynamics and cardiac wall motion ...
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    14. Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography

      Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography
      Angle-resolved low coherence interferometry (a/LCI) is an optical technique used to measure nuclear morphology in situ . However, a/LCI is not an imaging modality and can produce ambiguous results when the measurements are not properly oriented to the tissue architecture. Here we present a 2D a/LCI system which incorporates optical coherence tomography imaging to guide the measurements. System design and characterization are presented, along with example cases which ...
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  2. About University of Wisconsin

    University of Wisconsin

    University of Wisconsin System has established itself as one of the world's premier public university systems. The UW educates more than 173,000 students on 26 campuses, and serves more than one million citizens through statewide extension programs. The UW System's campuses in Madison and Milwaukee offer both undergraduate and graduate degree programs, including doctoral and professional programs. Eleven comprehensive campuses provide students both undergraduate and master's degree programs in smaller, more individualized academic settings. The UW System's 13 UW Colleges deliver freshman-sophomore courses for students seeking a foundation for a bachelor's degree.