1. University of Western Australia

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    1. Mentioned In 180 Articles

    3. Robust reconstruction of local optic axis orientation with fiber-based polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing
      Robust reconstruction of local optic axis orientation with fiber-based polarization-sensitive optical coherence tomography
      It is challenging to recover local optic axis orientation from samples probed with fiber-based polarization-sensitive optical coherence tomography (PS-OCT). In addition to the effect of preceding tissue layers, the transmission through fiber and system elements, and imperfect system alignment, need to be compensated. Here, we present a method to retrieve the required correction factors from measurements with depth-multiplexed PS-OCT, which accurately measures the full Jones matrix. The correction considers both ...
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      Mentions: Harvard University David D. Sampson University of Western Australia

    4. Retinal imaging with optical coherence tomography and low‐loss adaptive optics using a 2.8‐mm beam size

      Explore Wiley Online Library Ophthalmology
      Retinal imaging with optical coherence tomography and low‐loss adaptive optics using a 2.8‐mm beam size
      As data acquisition for retinal imaging with optical coherence tomography (OCT) becomes faster, efficient collection of photons becomes more important to maintain image quality. One approach is to use a larger aperture at the eyes pupil to collect more photons that have been reflected from the retina. A 2.8‐mm beam diameter system with only 7 reflecting surfaces was developed for low‐loss retinal imaging. The larger beam size ...
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      Mentions: University of Western Australia Barry Cense

    5. Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes

      Explore Nature Publishing Group Probes
      Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes
      Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical function and dimensions comparable to the optical fibre diameter. Recently, major advances in two-photon direct laser writing have enabled 3D printing of arbitrary three-dimensional micro/nanostructures with a surface roughness acceptable ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin

    7. Posterior Choroidal Stroma Reduces Accuracy of Automated Segmentation of Outer Choroidal Boundary in Swept Source Optical Coherence Tomography

      Explore IOVS Journal Ophthalmology
      Posterior Choroidal Stroma Reduces Accuracy of Automated Segmentation of Outer Choroidal Boundary in Swept Source Optical Coherence Tomography
      Purpose : To determine the influence of choroidal boundary morphology on the accuracy of automated measurements of subfoveal choroidal thickness (SFCT) in swept source optical coherence tomography (SSOCT). Methods : A retrospective image analysis of foveal-centered horizontal line scans from normal and diseased eyes using the Topcon DRI OCT-1 Atlantis SSOCT was conducted. Subfoveal choroid-scleral junction (CSJ) and retina-choroidal junction (RCJ) morphologies were graded by two observers. Automated SFCT (A-SFCT) was compared ...
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      Mentions: Topcon Medical Systems University of Western Australia University of Sydney

    8. Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography

      Explore LWW Online Ophthalmology
      Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography
      Purpose: To investigate the utility of optical coherence tomography angiography (OCTA) for detecting pathologic vascularization within pigment epithelial detachments (PEDs). Methods: This was a retrospective, cross-sectional, consecutive case series. Multimodal imaging (structural OCT, fluorescein, and indocyanine green angiography) was used as the gold standard to classify PEDs as nonvascularized or vascularized. Optical coherence tomography angiography imaging of the PED was subsequently and independently evaluated to classify PEDs as vascularized or ...
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      Mentions: Singapore Eye Research Institute LuEsther T. Mertz Retinal Research Center University of Western Australia

    10. Optical palpation for the visualization of tumor in human breast tissue

      Explore Wiley Online Library Oncology
      Optical palpation for the visualization of tumor in human breast tissue
      Accurate and effective removal of tumor in one operation is an important goal of breast‐conserving surgery. However, it is not always achieved. Surgeons often utilize manual palpation to assess the surgical margin and/or the breast cavity. Manual palpation, however, is subjective and has relatively low‐resolution. Here, we investigate a tactile imaging technique, optical palpation, for the visualization of tumor. Optical palpation generates maps of the stress at ...
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      Mentions: University of Western Australia Brendan F. Kennedy

    11. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

      Explore Wiley Online Library
      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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      Mentions: David D. Sampson University of Western Australia Qiang Wang

    12. Photonic force optical coherence elastography for three-dimensional mechanical microscopy

      Explore Nature Publishing Group
      Photonic force optical coherence elastography for three-dimensional mechanical microscopy
      Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise alignment associated with the excitation and detection of individual bead oscillations. In contrast, radiation pressure from a low-numerical aperture optical beam can apply transversely localized force over an extended depth range. Here we present photonic force optical coherence elastography (PF-OCE ...
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      Mentions: Cornell University University of Western Australia Steven G. Adie

    13. Realistic simulation and experiment reveals the importance of scatterer microstructure in optical coherence tomography image formation

      Explore OSA | OSA Publishing
      Realistic simulation and experiment reveals the importance of scatterer microstructure in optical coherence tomography image formation
      Realistic simulation of image formation in optical coherence tomography, based on Maxwells equations, has recently been demonstrated for sample volumes of practical significance. Yet, there remains a limitation whereby reducing the size of cells used to construct a computational grid, thus allowing for a more realistic representation of scatterer microstructure, necessarily reduces the overall sample size that can be modelled. This is a significant problem since, as is well known ...
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      Mentions: University College London David D. Sampson Nicolaus Copernicus University

    14. Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review

      Explore SAGE Journals Otolaryngology
      Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review
      Objective To evaluate the recent developments in optical coherence tomography (OCT) for tympanic membrane (TM) and middle ear (ME) imaging and to identify what further development is required for the technology to be integrated into common clinical use. Data Sources PubMed, Embase, Google Scholar, Scopus, and Web of Science. Review Methods A comprehensive literature search was performed for English language articles published from January 1966 to January 2018 with the ...
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      Mentions: University of Western Australia Brendan F. Kennedy Ruchire Eranga Wijesinghe

    15. Wide-field quantitative micro-elastography of human breast tissue

      Explore OSA | OSA Publishing
      Wide-field quantitative micro-elastography of human breast tissue
      Currently, 20-30% of patients undergoing breast-conserving surgery require a second surgery due to insufficient surgical margins in the initial procedure. We have developed a wide-field quantitative micro-elastography system for the assessment of tumor margins. In this technique, we map tissue elasticity over a field-of-view of ~46 46 mm. We performed wide-field quantitative micro-elastography on thirteen specimens of freshly excised tissue acquired from patients undergoing a mastectomy. We present wide-field optical ...
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      Mentions: University of Western Australia Andrea Curatolo Brendan F. Kennedy

    16. A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography

      Explore SPIE Digital Library Pulmonology
      A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography
      Airway inhalation injuries are present in up to a third of all major burns patients and are the leading cause of mortality among this population. Understanding the mechanism of injury could minimise oedema (swelling) and airway damage. In this study, we present an anatomical OCT (aOCT) imaging system, based on a 1300-nm wavelength, high-speed, long-range MEMS-VCSEL swept laser source, for real-time volumetric imaging and assessment of inhalation injuries in airways ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin
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  4. About University of Western Australia

    University of Western Australia

    University of Western Australia  is a leading Australian research university and has an international reputation for excellence, innovation and enterprise. A member of the Australian 'Group of Eight' research universities, it is also among Australia's leading research universities.

    The Optical and Biomedical Engineering Laboratory is in the School of Electrical, Electronic and Computer Engineering at the University of Western Australia in Perth, Western Australia.  OBEL's research is in the fields of biomedical optics, biophotonics, and optical microscopy. It is conducted at the interfaces of the disciplines of optics, biomedical engineering, biology and clinical medicine.

  5. Related Topics

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    2. Anatomical optical coherence tomography: a safe and effective tool for quantitative long-term monitoring of upper airway size and shape
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    3. Audio frequency in vivo optical coherence elastography
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