Articles that mention University of Western Australia -Optical Coherence Tomography News

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2. Clinical validation of the RTVue optical coherence tomography angiography image quality indicators
  
  Explore Wiley Online Library Nov 14 2019 Ophthalmology
  
  Importance All automated image quality indicators for en face optical coherence tomography angiography (OCTA) images require gold standard validation for determining optimal thresholds. Background A manual grading system (gold standard) for OCTA images was validated and compared to two automated image quality indicators: signal strength index (SSI) and scan quality index (SQI) generated by different software versions of the Optovue OCTA device. Design Retrospective cross‐sectional study. Participants 52 eyes ...
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  Mentions: Optovue University of Western Australia Fred K. Chen
3. Clinical feasibility of optical coherence elastography for tumour margin assessment in breast-conserving surgery (Thesis)
  
  Explore the UWA Profiles and Research Repository Nov 4 2019 Student Theses
  
  Currently, 20-30% of patients undergoing breast-conserving surgery require a second surgery due to tumour being found within the margin of the excised lump, determined days following surgery. The work presented in this thesis aims to develop a widefield optical coherence elastography system suitable for intraoperative margin assessment to reduce additional procedures. Early feasibility studies are presented investigating the ability for three optical coherence elastography variants to visualise a range of ...
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  Mentions: University of Western Australia
4. Recent progress in optical probing and manipulation of tissue: introduction
  
  Explore OSA | OSA Publishing Sep 17 2019
  
  This feature issue of Biomedical Optics Express represents a cross-section of the most recent work in tissue optics, including exciting developments in tissue optical clearing, deep tissue imaging, optical elastography, nanophotonics in tissue, and therapeutic applications of light, amongst others. A collection of 33 papers provides a comprehensive overview of current research in tissue optics, much of it inspired and informed by the pioneering work of Prof. Valery Tuchin. The ...
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  Mentions: Kirill V. Larin University of Houston David D. Sampson
5. Automatic choroidal segmentation in OCT images using supervised deep learning methods
  
  Explore Nature Publishing Group Sep 16 2019 Ophthalmology
  
  The analysis of the choroid in the eye is crucial for our understanding of a range of ocular diseases and physiological processes. Optical coherence tomography (OCT) imaging provides the ability to capture highly detailed cross-sectional images of the choroid yet only a very limited number of commercial OCT instruments provide methods for automatic segmentation of choroidal tissue. Manual annotation of the choroidal boundaries is often performed but this is impractical ...
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  Mentions: University of Queensland University of Western Australia Fred K. Chen
6. The Effect of Stent Artefact on Quantification of Plaque Features Using Optical Coherence Tomography (OCT): A Feasibility and Clinical Utility Study
  
  Explore ScienceDirect Jul 7 2019 Cardiology
  
  Background Optical coherence tomography (OCT) can detect detailed plaque features in native coronary arteries. Stent struts cause shadows that partially obscure the vessel wall, but plaque features can still be seen. We investigated the impact of stent artefact on plaque quantification and whether the plaque behind struts is associated with microvascular dysfunction. Methods Patients retrospectively recruited from two centres, underwent OCT pre- and post-stenting on the same vessel segment. Lipid ...
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  Mentions: University of Western Australia Gijs van Soest Jurgen M. Ligthart
7. Depth-resolved birefringence imaging of collagen fiber organization in the human oral mucosa in vivo
  
  Explore OSA | OSA Publishing Jun 5 2019
  
  Stromal collagen organization has been identified as a potential prognostic indicator in a variety of cancers and other diseases accompanied by fibrosis. Changes in the connective tissue are increasingly considered for grading dysplasia and progress of oral squamous cell carcinoma, investigated mainly ex vivo by histopathology. In this study, polarization-sensitive optical coherence tomography (PS-OCT) with local phase retardation imaging is used for the first time to visualize depth-resolved (i.e ...
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  Mentions: David D. Sampson University of Western Australia Julia Walther
8. Method and system for characterising biological tissue
  
  Explore uspto.gov Mar 19 2019 Patents , Probes
  
  The present disclosure provides a method for characterizing a region of interest within or between biological tissue. The method comprises inserting at least a portion of a probe into the region of interest and directing electromagnetic radiation to the region of interest and receiving electromagnetic radiation from the region of interest using the probe in a direction that is transversal to a length of the probe. Further, the method comprises ...
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  Mentions: University of Western Australia Robert A. McLaughlin Brendan F. Kennedy
9. Finger-mounted quantitative micro-elastography
  
  Explore OSA | OSA Publishing Mar 14 2019 Probes
  
  We present a finger-mounted quantitative micro-elastography (QME) probe, capable of measuring the elasticity of biological tissue in a format that avails of the dexterity of the human finger. Finger-mounted QME represents the first demonstration of a wearable elastography probe. The approach realizes optical coherence tomography-based elastography by focusing the optical beam into the sample via a single-mode fiber that is fused to a length of graded-index fiber. The fiber is ...
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  Mentions: University of Western Australia University of St. Andrews Andrea Curatolo
10. Optical probe at surgeon's fingertips for breast cancer removal
  
  Explore electronics360.globalspec.com Mar 14 2019 Oncology , Probes
  
  ...erpendicular to the body and pressed on the tissue while OCT images are recorded. Source: Rowan W. Sanderson, University of Western Australia sense of touch into high-resolution images. The system uses measurements from ...
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  Mentions: University of Western Australia
11. Analysis of spatial resolution in phase-sensitive compression optical coherence elastography
  
  Explore OSA | OSA Publishing Mar 6 2019
  
  Optical coherence elastography (OCE) is emerging as a method to image the mechanical properties of tissue on the microscale. However, the spatial resolution, a main advantage of OCE, has not been investigated and is not trivial to evaluate. To address this, we present a framework to analyze resolution in phase-sensitive compression OCE that incorporates the three main determinants of resolution: mechanical deformation of the sample, detection of this deformation using ...
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  Mentions: University of Western Australia Brendan F. Kennedy
12. Handheld optical palpation of turbid tissue with motion-artifact correction
  
  Explore OSA | OSA Publishing Jan 7 2019
  
  Handheld imaging probes are needed to extend the clinical translation of optical elastography to in vivo applications, yet such probes have received little attention. In this paper, we present the first demonstration of optical palpation using a handheld probe. Optical palpation is a variant of optical elastography that uses three-dimensional optical coherence tomography (3D-OCT) to provide maps of stress at the tissue surface under static compression. Using this technique, stiff ...
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  Mentions: University of Western Australia Andrea Curatolo Brendan F. Kennedy
13. Branch Retinal Vein Occlusion Secondary To A Retinal Arteriolar Macroaneurysm: A Novel Mechanism Supported By Multimodal Imaging
  
  Explore LWW Online Jan 1 2019 Ophthalmology
  
  Background/Purpose: To report a case of a branch retinal vein occlusion secondary to a retinal arteriolar macroaneurysm (RAM). Methods: Retrospective case report describing examination findings, treatment outcome and unique multimodal imaging features demonstrated on fluorescein angiography, optical coherence tomography, optical coherence tomography angiography and adaptive optics photography of the retinal vessels and RAM. Results: A 61-year-old man presented with 20/200 vision in the right eye because of a ...
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  Mentions: University of Western Australia
14. Short-time series optical coherence tomography angiography and its application to cutaneous microvasculature
  
  Explore OSA | OSA Publishing Dec 26 2018 Dermatology
  
  We present a new optical coherence tomography (OCT) angiography method for imaging tissue microvasculature in vivo based on the characteristic frequency-domain flow signature in a short time series of a single voxel. The angiography signal is generated by Fourier transforming the OCT signal time series from a given voxel in multiple acquisitions and computing the average magnitude of non-zero (high-pass) frequency components. Larger temporal variations of the OCT signal caused ...
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  Mentions: David D. Sampson University of Western Australia Qiang Wang
15. Research Fellow Opening at University of Western Australia
  
  Explore Optical Coherence Tomography News Oct 29 2018 Jobs & Studentships
  
  ...hematical Sciences School of Engineering Department of Electrical, Electronic and Computer Engineering The University of Western Australia (UWA) is ranked amongst the top 100 universities in the world and a member of ...
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  Mentions: University of Western Australia Sir Charles Gairdner Hospital Brendan F. Kennedy
16. Robust reconstruction of local optic axis orientation with fiber-based polarization-sensitive optical coherence tomography
  
  Explore OSA | OSA Publishing Oct 24 2018
  
  It is challenging to recover local optic axis orientation from samples probed with fiber-based polarization-sensitive optical coherence tomography (PS-OCT). In addition to the effect of preceding tissue layers, the transmission through fiber and system elements, and imperfect system alignment, need to be compensated. Here, we present a method to retrieve the required correction factors from measurements with depth-multiplexed PS-OCT, which accurately measures the full Jones matrix. The correction considers both ...
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  Mentions: Harvard University David D. Sampson University of Western Australia
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