1. University of Western Australia

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    1. Mentioned In 208 Articles

    2. Investigating Local Polarisation Contrast With Fibre-Based Polarisation-Sensitive Optical Coherence Tomography and Microscopy (Thesis)

      Investigating Local Polarisation Contrast With Fibre-Based Polarisation-Sensitive Optical Coherence Tomography and Microscopy (Thesis)
      This thesis makes several important contributions to polarisation-sensitive optical coherence tomography (PS-OCT) through developing no el methods to effectively extract local contrast from birefringence and the orientation of the associated optic axis, at conventional and ultra-high resolution.
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    3. Jones matrix‐based speckle‐decorrelation angiography using polarization‐sensitive optical coherence tomography

      Jones matrix‐based speckle‐decorrelation angiography using polarization‐sensitive optical coherence tomography
      We show that polarization‐sensitive optical coherence tomography angiography (PS‐OCTA) based on full Jones matrix assessment of speckle decorrelation offers improved contrast and depth of vessel imaging over conventional OCTA. We determine how best to combine the individual Jones matrix elements and compare the resulting image quality to that of a conventional OCT scanner by co‐locating and imaging the same skin locations with closely matched scanning setups. Vessel ...
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    4. Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery
      Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)based elastography technique ...
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    5. Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation

      Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation
      Significance: Optical coherence tomography (OCT) provides cross-sectional and volumetric images of backscattering from biological tissue that reveal the tissue morphology. The strength of the scattering, characterized by an attenuation coefficient, represents an alternative and complementary tissue optical property, which can be characterized by parametric imaging of the OCT attenuation coefficient. Over the last 15 years, a multitude of studies have been reported seeking to advance methods to determine the OCT ...
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    6. Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery
      Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)based elastography technique ...
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    7. Coronary Artery Segmentation from Intravascular Optical Coherence Tomography Using Deep Capsules

      Coronary Artery Segmentation from Intravascular Optical Coherence Tomography Using Deep Capsules
      The segmentation and analysis of coronary arteries from intravascular optical coherence tomography (IVOCT) is an important aspect of diagnosing and managing coronary artery disease. However, automated, robust IVOCT image analysis tools are lacking. Current image processing methods are hindered by the time needed to generate these expert-labelled datasets and also the potential for bias during the analysis. Here we present a new deep learning method based on capsules to automatically ...
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    8. Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast

      Three‐dimensional mapping of the attenuation coefficient in optical coherence tomography to enhance breast tissue micro‐architecture contrast
      Effective intraoperative tumor margin assessment is needed to reduce re‐excision rates in breast‐conserving surgery (BCS). Mapping the attenuation coefficient in optical coherence tomography (OCT) throughout a sample to create an image (attenuation imaging) is one promising approach. For the first time, three‐dimensional OCT attenuation imaging of human breast tissue micro‐architecture using a wide‐field (up to ~45453.5mm) imaging system is demonstrated. Representative results from three ...
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    9. Handheld volumetric manual compression‐based quantitative micro‐elastography

      Handheld volumetric manual compression‐based quantitative micro‐elastography
      Compression optical coherence elastography typically requires a mechanical actuator to impart a controlled uniform strain to the sample. However, for handheld scanning, this adds complexity to the design of the probe and the actuator stroke limits the amount of strain that can be applied. In this work, we present a new volumetric imaging approach that utilises bidirectional manual compression via the natural motion of the user's hand to induce ...
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    10. RTVue XR AngioVue Optical Coherence Tomography Angiography Software Upgrade Impacts on Retinal Thickness and Vessel Density Measurements

      RTVue XR AngioVue Optical Coherence Tomography Angiography Software Upgrade Impacts on Retinal Thickness and Vessel Density Measurements
      Purpose : To determine the impact of an AngioVue software upgrade on total retinal thickness (RT) and inner retinal vessel density (VD) measurements derived from optical coherence tomography angiography (OCTA). Methods : Optovue OCTA images (3 3 mm) from 126 individuals (105 healthy eyes and 72 eyes with retinal disease) were acquired before an upgrade of the AngioVue software, which resulted in an inward shift of the outer boundary of the inner ...
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    11. Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus

      Vectorial birefringence imaging by optical coherence microscopy for assessing fibrillar microstructures in the cornea and limbus
      The organization of fibrillar tissue on the micrometer scale carries direct implications for health and disease but remains difficult to assess in vivo . Polarization-sensitive optical coherence tomography measures birefringence, which relates to the microscopic arrangement of fibrillar tissue components. Here, we demonstrate a critical improvement in leveraging this contrast mechanism by employing the improved spatial resolution of focus-extended optical coherence microscopy (1.4 m axially in air and 1.6 ...
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    12. SURGICAL MANAGEMENT OF TRAUMATIC MACULAR HOLE Optical Coherence Tomography Features and Outcomes

      SURGICAL MANAGEMENT OF TRAUMATIC MACULAR HOLE Optical Coherence Tomography Features and Outcomes
      Purpose: To report the outcomes of eyes receiving surgical management for traumatic macular holes. To describe the preoperative and postoperative optical coherence tomography features of traumatic macular holes and to explore associations between preoperative clinical and optical coherence tomography features, and visual outcome. Methods: Retrospective study of patients undergoing vitrectomy for traumatic macular hole and entered into the Australian and New Zealand Society of Retinal Specialists surgical registry. Preoperative clinical ...
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    13. 1-15 of 208 1 2 3 4 ... 12 13 14 »
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  2. About University of Western Australia

    University of Western Australia

    University of Western Australia  is a leading Australian research university and has an international reputation for excellence, innovation and enterprise. A member of the Australian 'Group of Eight' research universities, it is also among Australia's leading research universities.

    The Optical and Biomedical Engineering Laboratory is in the School of Electrical, Electronic and Computer Engineering at the University of Western Australia in Perth, Western Australia.  OBEL's research is in the fields of biomedical optics, biophotonics, and optical microscopy. It is conducted at the interfaces of the disciplines of optics, biomedical engineering, biology and clinical medicine.