1. University of Western Australia

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    1. Mentioned In 171 Articles

    2. Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography

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      Label‐free volumetric imaging of conjunctival collecting lymphatics ex vivo by optical coherence tomography lymphangiography
      We employ optical coherence tomography (OCT) and optical coherence microscopy (OCM) to study conjunctival lymphatics in porcine eyes ex vivo . This study is a precursor to the development of in vivo imaging of the collecting lymphatics for potentially guiding and monitoring glaucoma filtration surgery. OCT scans at 1300 nm and higher‐resolution OCM scans at 785 nm reveal the lymphatic vessels via their optical transparency. Equivalent signal characteristics are also ...
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      Mentions: David D. Sampson University of Western Australia Qiang Wang

    3. Photonic force optical coherence elastography for three-dimensional mechanical microscopy

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      Photonic force optical coherence elastography for three-dimensional mechanical microscopy
      Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise alignment associated with the excitation and detection of individual bead oscillations. In contrast, radiation pressure from a low-numerical aperture optical beam can apply transversely localized force over an extended depth range. Here we present photonic force optical coherence elastography (PF-OCE ...
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      Mentions: Cornell University University of Western Australia Steven G. Adie

    4. Realistic simulation and experiment reveals the importance of scatterer microstructure in optical coherence tomography image formation

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      Realistic simulation and experiment reveals the importance of scatterer microstructure in optical coherence tomography image formation
      Realistic simulation of image formation in optical coherence tomography, based on Maxwells equations, has recently been demonstrated for sample volumes of practical significance. Yet, there remains a limitation whereby reducing the size of cells used to construct a computational grid, thus allowing for a more realistic representation of scatterer microstructure, necessarily reduces the overall sample size that can be modelled. This is a significant problem since, as is well known ...
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      Mentions: University College London David D. Sampson Nicolaus Copernicus University

    5. Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review

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      Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review
      Objective To evaluate the recent developments in optical coherence tomography (OCT) for tympanic membrane (TM) and middle ear (ME) imaging and to identify what further development is required for the technology to be integrated into common clinical use. Data Sources PubMed, Embase, Google Scholar, Scopus, and Web of Science. Review Methods A comprehensive literature search was performed for English language articles published from January 1966 to January 2018 with the ...
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      Mentions: University of Western Australia Brendan F. Kennedy Ruchire Eranga Wijesinghe

    6. Wide-field quantitative micro-elastography of human breast tissue

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      Wide-field quantitative micro-elastography of human breast tissue
      Currently, 20-30% of patients undergoing breast-conserving surgery require a second surgery due to insufficient surgical margins in the initial procedure. We have developed a wide-field quantitative micro-elastography system for the assessment of tumor margins. In this technique, we map tissue elasticity over a field-of-view of ~46 46 mm. We performed wide-field quantitative micro-elastography on thirteen specimens of freshly excised tissue acquired from patients undergoing a mastectomy. We present wide-field optical ...
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      Mentions: University of Western Australia Andrea Curatolo Brendan F. Kennedy

    7. A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography

      Explore SPIE Digital Library Pulmonology
      A study of the effects of supine position and fluid intake on normal airway geometry using anatomical optical coherence tomography
      Airway inhalation injuries are present in up to a third of all major burns patients and are the leading cause of mortality among this population. Understanding the mechanism of injury could minimise oedema (swelling) and airway damage. In this study, we present an anatomical OCT (aOCT) imaging system, based on a 1300-nm wavelength, high-speed, long-range MEMS-VCSEL swept laser source, for real-time volumetric imaging and assessment of inhalation injuries in airways ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin

    8. Quantitative comparisons between optical coherence tomography angiography and matched histology in the human eye

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      Quantitative comparisons between optical coherence tomography angiography and matched histology in the human eye
      The aim was to quantitatively compare retinal vascular detail as seen on optical coherence tomography angiography (OCTA) and matched histology in the human eye. 13 normal human donor eyes were used. The central retinal artery was cannulated after which human packed red blood cells were perfused through the retinal vasculature. Retinal vessels were imaged using a custom-built OCTA device during red blood cell perfusion. The eye was subsequently perfused with ...
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      Mentions: University of Western Australia Marinko V. Sarunic Simon Fraser University

    9. Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye

      Explore OSA | OSA Publishing Ophthalmology
      Swept source optical coherence tomography and tunable lens technology for comprehensive imaging and biometry of the whole eye
      Standard optical systems in ophthalmology are strictly dedicated either to retinal or to anterior segment imaging due to the refractive properties of the eye. We demonstrate a swept source optical coherence tomography platform with an electrically tunable lens (ETL) for versatile 3D in vivo imaging of both the eyes anterior segment and the retina. The optimized optical setup with adaptive operational states of the ETL permits focusing on the retina ...
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      Mentions: Nicolaus Copernicus University University of Western Australia Karol Karnowski

    10. Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment

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      Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment
      The biannual International Conference on Biophotonics was recently held on April 30 to May 1, 2017, in Fremantle, Western Australia. This continuing conference series brought together key opinion leaders in biophotonics to present their latest results and, importantly, to participate in discussions on the future of the field and what opportunities exist when we collectively work together for using biophotonics for biological discovery and medical applications. One session in this ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign University of Western Australia

    11. Photonic force optical coherence elastography for threedimensional mechanical microscopy

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      Photonic force optical coherence elastography for threedimensional mechanical microscopy
      Optical tweezers are an invaluable tool for non-contact trapping and micro-manipulation, but their ability to facilitate high-throughput volumetric microrheology of biological samples for mechanobiology research is limited by the precise alignment associated with the excitation and detection of individual bead oscillations. In contrast, radiation pressure from a low numerical aperture optical beam can apply transversely localized force over an extended depth range. We propose photonic force optical coherence elastography (PF-OCE ...
      Read Full Article
      Mentions: Cornell University University of Western Australia Steven G. Adie

    12. Special Section Guest Editorial: Commemorating 25 Years of Optical Coherence Tomography: a Perspective on Biomedical Applications

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      Special Section Guest Editorial: Commemorating 25 Years of Optical Coherence Tomography: a Perspective on Biomedical Applications
      ptical coherence tomography (OCT) has become a major medical imaging technology in the time since its inception now more than 25 years ago. During this time, OCT has become very well established in ophthalmology, and this application area largely dominates the field. Next in importance and stage of development is cardiovascular medicine, also a strongly commercial technology, but at an earlier stage and a slower pace of uptake than ophthalmology ...
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      Mentions: Peter E. Andersen David D. Sampson University of Washington

    13. Ultrahigh-Resolution Optical Coherence Elastography Images Cellular-Scale Stiffness of Mouse Aorta

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      Ultrahigh-Resolution Optical Coherence Elastography Images Cellular-Scale Stiffness of Mouse Aorta
      Cellular-scale imaging of the mechanical properties of tissue has helped to reveal the origins of disease; however, cellular-scale resolution is not readily achievable in intact tissue volumes. Here, we demonstrate volumetric imaging of Youngs modulus using ultrahigh-resolution optical coherence elastography, and apply it to characterizing the stiffness of mouse aortas. We achieve isotropic resolution of better than 15 m over a 1-mm lateral field of view through the entire depth ...
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      Mentions: David D. Sampson University of Western Australia Andrea Curatolo

    14. Research Associate / Research Fellow Microscope-in-a-Needle at the University of Western Australia

      Explore Optical Coherence Tomography News Jobs & Studentships
      Research Associate / Research Fellow Microscope-in-a-Needle at the University of Western Australia
      ...fications and experience) Research & Development In Biomedical Photonics/Optical Microscopy (Australia) The University of Western Australia (UWA) is ranked amongst the top Australian universities and a member of the pr...
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      Mentions: David D. Sampson University of Western Australia Karol Karnowski

    15. Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration

      Explore SPIE Digital Library Pulmonology
      Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration
      Transbronchial needle aspiration (TBNA) of small lesions or lymph nodes in the lung may result in nondiagnostic tissue samples. We demonstrate the integration of an optical coherence tomography (OCT) probe into a 19-gauge flexible needle for lung tissue aspiration. This probe allows simultaneous visualization and aspiration of the tissue. By eliminating the need for insertion and withdrawal of a separate imaging probe, this integrated design minimizes the risk of dislodging ...
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      Mentions: David D. Sampson University of Western Australia Robert A. McLaughlin
    17. 1-15 of 171 1 2 3 4 ... 10 11 12 »
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  4. About University of Western Australia

    University of Western Australia

    University of Western Australia  is a leading Australian research university and has an international reputation for excellence, innovation and enterprise. A member of the Australian 'Group of Eight' research universities, it is also among Australia's leading research universities.

    The Optical and Biomedical Engineering Laboratory is in the School of Electrical, Electronic and Computer Engineering at the University of Western Australia in Perth, Western Australia.  OBEL's research is in the fields of biomedical optics, biophotonics, and optical microscopy. It is conducted at the interfaces of the disciplines of optics, biomedical engineering, biology and clinical medicine.

  5. Related Topics

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      132 articles also mentioned David D. Sampson
    2. Anatomical optical coherence tomography: a safe and effective tool for quantitative long-term monitoring of upper airway size and shape
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    3. Audio frequency in vivo optical coherence elastography
      49 articles also mentioned Brendan F. Kennedy
    4. Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography
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