Articles that mention University of Western Australia -Optical Coherence Tomography News

University of Western Australia

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2. Retinal layer thicknesses retrieved with different segmentation algorithms from optical coherence tomography scans acquired under different signal-to-noise ratio conditions
  
  Explore OSA | OSA Publishing Nov 15 2020 Ophthalmology
  
  Glaucomatous damage can be quantified by measuring the thickness of different retinal layers. However, poor image quality may hamper the accuracy of the layer thickness measurement. We determined the effect of poor image quality (low signal-to-noise ratio) on the different layer thicknesses and compared different segmentation algorithms regarding their robustness against this degrading effect. For this purpose, we performed OCT measurements in the macular area of healthy subjects and degraded ...
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  Mentions: University of Western Australia Barry Cense Yonsei University
3. Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated
  
  Explore TVST Journal Oct 17 2020 Ophthalmology
  
  Purpose : To use a deep learning model to develop a fully automated method (fully semantic network and graph search [FS-GS]) of retinal segmentation for optical coherence tomography (OCT) images from patients with Stargardt disease. Methods : Eighty-seven manually segmented (ground truth) OCT volume scan sets (5171 B-scans) from 22 patients with Stargardt disease were used for training, validation and testing of a novel retinal boundary detection approach (FS-GS) that combines a ...
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  Mentions: University of Queensland University of Western Australia Fred K. Chen
4. Camera-based optical palpation
  
  Explore Nature Publishing Group Oct 7 2020
  
  Optical elastography is undergoing extensive development as an imaging tool to map mechanical contrast in tissue. Here, we present a new platform for optical elastography by generating sub-millimetre-scale mechanical contrast from a simple digital camera. This cost-effective, compact and easy-to-implement approach opens the possibility to greatly expand applications of optical elastography both within and beyond the field of medical imaging. Camera-based optical palpation (CBOP) utilises a digital camera to acquire ...
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  Mentions: University of Western Australia Andrea Curatolo Brendan F. Kennedy
5. Detection of localized pulsatile motion in cutaneous microcirculation by speckle decorrelation optical coherence tomography angiography
  
  Explore SPIE Digital Library Sep 17 2020 Dermatology
  
  Significance: Pulsatility is a vital characteristic of the cardiovascular system. Characterization of the pulsatility pattern locally in the peripheral microvasculature is currently not readily available and would provide an additional source of information, which may prove important in understanding the pathophysiology of arterial stiffening, vascular ageing, and their linkage with cardiovascular disease development. Aim: We aim to confirm the suitability of speckle decorrelation optical coherence tomography angiography (OCTA) under various ...
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  Mentions: David D. Sampson University of Western Australia Qiang Wang
6. Influence of tissue fixation on depth-resolved birefringence of oral cavity tissue samples
  
  Explore SPIE Digital Library Sep 12 2020 Dentistry
  
  Significance: To advance our understanding of the contrast observed when imaging with polarization-sensitive optical coherence tomography (PS-OCT) and its correlation with oral cancerous pathologies, a detailed comparison with histology provided via ex vivo fixed tissue is required. The effects of tissue fixation, however, on such polarization-based contrast have not yet been investigated. Aim: A study was performed to assess the impact of tissue fixation on depth-resolved (i.e., local) birefringence ...
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  Mentions: Massachusetts General Hospital Harvard University David D. Sampson
7. In vivo imaging of the depth-resolved optic axis of birefringence in human skin
  
  Explore OSA | OSA Publishing Sep 2 2020
  
  Recent progress has enabled the reconstruction of the local (i.e., depth-resolved) optic axis (OAx) of biological tissue from measurements made with polarization-sensitive optical coherence tomography (PS-OCT). Here we demonstrate local OAx imaging in healthy human skin in vivo . The images reveal dense, weaving patterns that are imperceptible in OCT intensity tomograms or conventional PS-OCT metrics and that suggest a mesh-like tissue organization, consistent with the morphology of dermal collagen ...
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  Mentions: Massachusetts General Hospital Harvard University David D. Sampson
8. Optical coherence tomography: a novel imaging approach to visualize and quantify cutaneous microvascular structure and function in patients with diabetes.
  
  Explore BMJ Open Diabetes Research & Care Aug 29 2020 Dermatology
  
  Introduction The pathophysiology of microvascular disease is poorly understood, partly due to the lack of tools to directly image microvessels in vivo. Research design and methods In this study, we deployed a novel optical coherence tomography (OCT) technique during local skin heating to assess microvascular structure and function in diabetics with (DFU group, n=13) and without (DNU group, n=10) foot ulceration, and healthy controls (CON group, n=13 ...
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  Mentions: University of Western Australia
9. Contrast-free optical coherence tomography: Systematic evaluation of non-contrast media for intravascular assessment
  
  Explore Journals | PLOS Aug 25 2020 Cardiology
  
  Background Coronary revascularization using imaging guidance is rapidly becoming the standard of care. Intravascular optical coherence tomography uses near-infrared light to obtain high resolution intravascular images. Standard optical coherence tomography imaging technique employs iodinated contrast dye to achieve the required blood clearance during acquisition. We sought to systematically evaluate the technical performance of saline as an alternative to iodinated contrast for intravascular optical coherence tomography assessment. Methods and results We ...
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  Mentions: University of Western Australia University of Calgary University of Ottawa
10. Strain and elasticity imaging in compression optical coherence elastography: the two‐decade perspective and recent advances
  
  Explore Wiley Online Library Aug 5 2020
  
  Quantitative mapping of deformation and elasticity in optical coherence tomography has attracted much attention of researchers during the last two decades. However, despite intense effort it took ~15years to demonstrate optical coherence elastography (OCE) as a practically useful technique. Similarly to medical ultrasound, where elastography was first realized using the quasi‐static compression principle and later shear‐wave‐based systems were developed, in OCE these two approaches also developed in ...
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  Mentions: University of Western Australia Institute of Applied Physics Brendan F. Kennedy
11. Change in Leadership at OBEL, The University of Western Australia
  
  Explore Optical Coherence Tomography News Aug 4 2020
  
  ... moving fast in OCT, but I was working…. still in telecoms. It wasn’t until starting my own group back at the University of Western Australia, that I could shift fields to biomedical optics and begin to pursue OCT. For t...
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  Mentions: Adrian G. Podoleanu University of Kent David D. Sampson
12. Investigating Local Polarisation Contrast With Fibre-Based Polarisation-Sensitive Optical Coherence Tomography and Microscopy (Thesis)
  
  Explore Pure API May 31 2020 Student Theses
  
  This thesis makes several important contributions to polarisation-sensitive optical coherence tomography (PS-OCT) through developing no el methods to effectively extract local contrast from birefringence and the orientation of the associated optic axis, at conventional and ultra-high resolution.
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  Mentions: University of Western Australia
13. Jones matrix‐based speckle‐decorrelation angiography using polarization‐sensitive optical coherence tomography
  
  Explore Wiley Online Library May 22 2020
  
  We show that polarization‐sensitive optical coherence tomography angiography (PS‐OCTA) based on full Jones matrix assessment of speckle decorrelation offers improved contrast and depth of vessel imaging over conventional OCTA. We determine how best to combine the individual Jones matrix elements and compare the resulting image quality to that of a conventional OCT scanner by co‐locating and imaging the same skin locations with closely matched scanning setups. Vessel ...
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  Mentions: David D. Sampson University of Western Australia Qiang Wang
14. OCT Shines with a New Type of Contrast
  
  Explore Home: SPIE.org Apr 26 2020
  
  ...ed review collects perspectives of several international groups involved in OCT researchincluding groups from University of Western Australia, University of Amsterdam and Erasmus Medical Center in The Netherlands, and Un...
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  Mentions: James G. Fujimoto Vanderbilt University University of Western Australia
15. Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery
  
  Explore Optical Coherence Tomography News Apr 26 2020 Oncology
  
  Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)based elastography technique ...
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  Mentions: University of Western Australia Andrea Curatolo Brendan F. Kennedy
16. Optical coherence tomography shines with a new type of contrast
  
  Explore PhysOrg.com Apr 20 2020 Ophthalmology
  
  ...d review collects perspectives of several international groups involved in OCT research—including groups from University of Western Australia, University of Amsterdam and related medical centers in The Netherlands, and U...
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  Mentions: Vanderbilt University University of Western Australia
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