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2. Regression patterns of central serous chorioretinopathy using en face optical coherence tomography
  
  Explore Home - Springer Apr 1 2022 Ophthalmology
  
  Purpose To study the regression patterns of subretinal fluid (SRF) in central serous chorioretinopathy (CSCR) on sequential en face optical coherence tomography (OCT) and its relationship to leak locations. Methods Retrospective study on patients with acute CSCR. Inclusion criteria were (i) availability of data, sequential OCT and OCT angiography (B scan and en face OCT) every 2 weeks until resolution of SRF or 6 months, whichever is earlier; (ii) single ...
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  Mentions: University of Waterloo
3. 400 kHz Spectral Domain Optical Coherence Tomography for Corneal Imaging
  
  Explore UWSpace Home Feb 3 2022 Ophthalmology , Student Theses
  
  The cornea is the transparent, outermost layer of the human eye that contributes approximately 70% of the refractive power of the eye in air. It is composed of five major tissue layers: the epithelium, the Bowmans membrane, the stroma, the Descemets membrane, and the endothelium. Corneal diseases such as Keratoconus and Fuchs dystrophy can change the morphology of some or all of the corneal layers, which can lead to vision ...
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  Mentions: University of Waterloo
4. Wide-field optical coherence tomography imaging in diabetic retinopathy
  
  Explore SAGE Journals Nov 10 2021 Ophthalmology
  
  Purpose: To report the individual retinal layer thicknesses up to mid-equator in patients with diabetic retinopathy (DR) using Spectralis (Heidelberg Engineering, Heidelberg, Germany) wide-field optical coherence tomography (OCT). Methods: Retinal layers were segmented using a custom designed semi-automated algorithm, where reference points were marked by the examiner to enable software to automatically compute the thickness values of each retinal sublayer at an interval of 1 mm from reference points. The ...
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  Mentions: University of Waterloo UCSD University of Perugia
5. ODTiD: Optic Nerve Head SD-OCT Image Dataset
  
  Explore Medical Journals Publisher Oct 20 2021 Ophthalmology
  
  Introduction: Optic disc tilt (ODT) or tilted optic disc is a common finding in the general population. It is due to anomalous development caused by the malclosure of the embryonic optic fissure. ODT is commonly associated with high myopia as well as other conditions. In recent days, the common method to image the optic disc (OD) is by optical coherence tomography (OCT). To the best of our knowledge, there are ...
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  Mentions: University of Waterloo Carl Zeiss Meditec
6. Three-dimensional virtual histology in unprocessed resected tissues with photoacoustic remote sensing (PARS) microscopy and optical coherence tomography (OCT)
  
  Explore Nature Publishing Group Jul 4 2021 Oncology
  
  Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, current methods for capturing these microscopy images require resource intensive tissue preparation that may delay diagnosis for days or weeks. To streamline this process, clinicians are limited to assessing small macroscopically representative subsets of tissues. Here, a combined photoacoustic remote sensing (PARS) microscope and swept source optical coherence tomography system designed to circumvent these diagnostic limitations is presented ...
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  Mentions: University of Waterloo University of Alberta
7. Functional and structural ophthalmic imaging using noncontact multimodal photoacoustic remote sensing microscopy and optical coherence tomography
  
  Explore Nature Publishing Group Jun 3 2021 Microscopy
  
  Early diagnosis of ocular diseases improves the understanding of pathophysiology and aids in accurate monitoring and effective treatment. Advanced, multimodal ocular imaging platforms play a crucial role in visualization of ocular components and provide clinicians with a valuable tool for evaluating various eye diseases. Here, for the first time we present a non-contact, multiwavelength photoacoustic remote sensing (PARS) microscopy and swept-source optical coherence tomography (SS-OCT) for in-vivo functional and structural ...
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8. Validation of Optical Coherence Tomography Retinal Segmentation in Neurodegenerative Disease
  
  Explore TVST Journal Sep 17 2019 Ophthalmology
  
  Purpose : This study assessed agreement between an automated spectral-domain optical coherence tomography (SD-OCT) retinal segmentation software and manually corrected segmentation to validate its use in a prospective clinical study of neurodegenerative diseases (NDD). Methods : The sample comprised 30 subjects with NDD, including vascular cognitive impairment, frontotemporal dementia, Parkinson's disease, and Alzheimer's disease. Macular SD-OCT scans were acquired and segmented using Heidelberg Spectralis. For the central foveal B scan ...
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  Mentions: University of Toronto University of Waterloo
9. OCTID: Optical Coherence Tomography Image Database
  
  Explore arxiv.org Dec 22 2018 Ophthalmology
  
  Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for the early diagnosis of retinal diseases. In this paper, we describe a comprehensive open-access database containing more than 500 high-resolution images categorized into different pathological conditions. The image classes include Normal (NO), Macular Hole (MH), Age-related Macular Degeneration (AMD), Central Serous ...
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10. 250 kHz, 1.5 µm resolution SD-OCT for in-vivo cellular imaging of the human cornea
  
  Explore OSA | OSA Publishing Nov 29 2018 Microscopy , Ophthalmology
  
  We present the first spectral domain optical coherence tomography (SD-OCT) system that combines an isotropic imaging resolution of ~1.5 m in biological tissue with a 250 kHz image acquisition rate, for in vivo non-contact, volumetric imaging of the cellular structure of the human cornea. OCT images of the healthy human cornea acquired with this system reveal the cellular structure of the corneal epithelium, cellular debris and mucin clusters in ...
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  Mentions: University of Waterloo Singapore Eye Research Institute
11. Lid-parallel conjunctival fold (LIPCOF) morphology imaged by optical coherence tomography and its relationship to LIPCOF grade
  
  Explore ScienceDirect Nov 17 2018 Ophthalmology
  
  Purpose Lid-parallel conjunctival folds (LIPCOF) are a well-accepted clinical sign in dry eye diagnosis. Commonly, LIPCOF is classified by grading the number of folds observed by slit-lamp microscope. This study investigated the relationship between subjective grading scale and LIPCOF morphology imaged by optical coherence tomography (OCT). Methods Temporal and nasal LIPCOF of 42 subjects (mean age 27.38.4 (SD) years; 13M, 29F) were observed and classified by an experienced ...
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  Mentions: University of Waterloo Cardiff University Carl Zeiss Meditec
12. Visualisation of the visual system
  
  Explore Wiley Online Library Oct 24 2018 Ophthalmology
  
  In vivo imaging techniques have had a major impact on vision science research, not least because they provide access to the entire human visual pathway from the anterior eye to higher‐level processing areas within the brain. A special issue of Ophthalmic Physiological Optics titled Imaging the visual system: from the eye to the brain 1 highlighted the breadth of imaging‐related research in vision science by including papers that ...
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  Mentions: University of Waterloo Specsavers
13. Comparative Study of Optical Coherence Tomography Angiography and Phase-Resolved Doppler Optical Coherence Tomography for Measurement of Retinal Blood Vessels Caliber
  
  Explore TVST Journal Aug 28 2018 Ophthalmology
  
  Purpose : To compare the accuracy of Doppler optical coherence tomography (DOCT) and OCT angiography (OCTA) for measuring retinal blood vessel caliber at different flow rates. Methods : A research-grade 1060-nm OCT system with 3.5-m axial resolution in retinal tissue and 92,000 A scan/s image acquisition rate was used in this study. DOCT and OCTA measurements were acquired both from a flow phantom and in vivo from retinal blood ...
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14. Automated Segmentation of Retinal Optical Coherence Tomography Images (Thesis)
  
  Explore UWSpace Home Aug 25 2018 Ophthalmology , Student Theses
  
  Aim Optical Coherence Tomography (OCT) is a fast and non-invasive medical imaging technique which helps in the investigation of each individual retinal layer structure. For early detection of retinal diseases and the study of their progression, segmentation of the OCT images into the distinct layers of the retina plays a crucial role. However, segmentation done by the clinicians manually is extremely tedious, time-consuming and variable with respect to the expertise ...
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15. Developing algorithms for the analysis of retinal Optical Coherence Tomography images (Thesis)
  
  Explore UWSpace Home Aug 24 2018 Ophthalmology , Student Theses
  
  Vision loss, with a prevalence loss greater than 42 million in the United States is one of the major challenges of today's health-care industry and medical science. Early detection of different retinal-related diseases will dramatically reduce the risk of vision loss. Optical Coherence Tomography (OCT) is a relatively new imaging technique which is of great importance in the identification of ocular and especially retinal diseases. Thus, the efficient analysis ...
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16. Classification of optical coherence tomography images for diagnosing different ocular diseases
  
  Explore SPIE Digital Library Mar 24 2018 Ophthalmology
  
  Optical Coherence tomography (OCT) images provide several indicators, e.g., the shape and the thickness of different retinal layers, which can be used for various clinical and non-clinical purposes. We propose an automated classification method to identify different ocular diseases, based on the local binary pattern features. The database consists of normal and diseased human eye SD-OCT images. We use a multiphase approach for building our classifier, including preprocessing, Meta ...
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  Mentions: University of Waterloo
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