1. University of Washington

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    1. Mentioned In 328 Articles

    2. Optical microangiography provides correlation between microstructure and microvasculature of optic nerve head in human subjects

      Optical microangiography provides correlation between microstructure and microvasculature of optic nerve head in human subjects
      It is demonstrated that optical microangiography (OMAG) is capable of imaging the detailed microstructure and microvasculature of the in vivo human optic nerve head (ONH), including the prelaminar tissue, the lamina cribrosa, the scleral rim and the vessels in the region of the circle of Zin-Haller. For demonstration, an ultrahigh sensitive OMAG system operating in the 850 nm wavelength region and a 500 kHz A-scan rate resulting in a spatial ...
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    3. Digital focusing of OCT images based on scalar diffraction theory and information entropy

      Digital focusing of OCT images based on scalar diffraction theory and information entropy
      This paper describes a digital method that is capable of automatically focusing optical coherence tomography (OCT) en face images without prior knowledge of the point spread function of the imaging system. The method utilizes a scalar diffraction model to simulate wave propagation from out-of-focus scatter to the focal plane, from which the propagation distance between the out-of-focus plane and the focal plane is determined automatically via an image-definition-evaluation criterion based ...
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    4. Label-free imaging of blood vessel morphology with capillary resolution using optical microangiography

      Label-free imaging of blood vessel morphology with capillary resolution using optical microangiography
      Several tissue pathologies are correlated with changes in the blood vessel morphology and microcirculation that supplies the tissue. Optical coherence tomography (OCT) is an imaging technique that enables acquiring non-invasive three-dimensional images of biological structures with micrometer resolution. Optical microangiography (OMAG) is a method of processing OCT data which enables visualizing the three-dimensional blood vessel morphology within biological tissues. OMAG has high spatial resolution which allows visualizing single capillary vessels ...
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    5. Extracting cardiac shapes and motion of the chick embryo heart outflow tract from four-dimensional optical coherence tomography images

      Extracting cardiac shapes and motion of the chick embryo heart outflow tract from four-dimensional optical coherence tomography images
      ...analysis of cardiac motion. Oregon Health & Science University, Heart Research Center, Portland, Oregon 97239 University of Washington, Department of Bioengineering, Seattle, Washington 98195 Abstract.  Recent advances ...
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    6. In vivo functional imaging of blood flow and wall strain rate in outflow tract of embryonic chick heart using ultrafast spectral domain optical coherence tomography

      In vivo functional imaging of blood flow and wall strain rate in outflow tract of embryonic chick heart using ultrafast spectral domain optical coherence tomography
      ...blood flow provides a useful approach to better understand cardiac dynamics during early developmental stages University of Washington, Department of Bioengineering, Seattle, Washington 98195 Oregon Health & Science Univ...
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    7. Impact of intraocular pressure on changes of blood flow in the retina, choroid, and optic nerve head in rats investigated by optical microangiography

      Impact of intraocular pressure on changes of blood flow in the retina, choroid, and optic nerve head in rats investigated by optical microangiography
      In this paper, we demonstrate the use of optical coherence tomography/optical microangiography (OCT/OMAG) to image and measure the effects of acute intraocular pressure (IOP) elevation on retinal, choroidal and optic nerve head (ONH) perfusion in the rat eye. In the experiments, IOP was elevated from 10 to 100 mmHg in 10 mmHg increments. At each IOP level, three-dimensional data volumes were captured using an ultrahigh sensitive (UHS) OMAG ...
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    8. Maturation of the Human Fovea: Correlation of Spectral-Domain Optical Coherence Tomography Findings With Histology

      Maturation of the Human Fovea: Correlation of Spectral-Domain Optical Coherence Tomography Findings With Histology
      ...e University Eye Center, Durham, North Carolina , * Daniel Possin Affiliations + Department of Ophthalmology, University of Washington, Seattle, Washington , * Stephanie J. Chiu Affiliations + Department of Biomedical En...
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    9. Washington University Receives a 2012 NIH Grant for Smart Laser Treatment of Port-Wine Stain in Children

      Washington University Receives a 2012 NIH Grant for Smart Laser Treatment of Port-Wine Stain in Children
      Washington University Receives a 2012 NIH Grant for $84,965 for Smart Laser Treatment of Port-Wine Stain in Children. The program is a multi-year program and started in 2012 and ends in 2014. The principle investigator is Bin Rao. A brief description of the project is given below. Due to the lack of port-wine stain (PWS) lesion information, there is a fundamental gap in achieving the optimum therapeutic outcome of ...
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    10. Biomechanics of the Chick Embryonic Heart Outflow Tract at HH18 Using 4D Optical Coherence Tomography Imaging and Computational Modeling

      Biomechanics of the Chick Embryonic Heart Outflow Tract at HH18 Using 4D Optical Coherence Tomography Imaging and Computational Modeling
      During developmental stages, biomechanical stimuli on cardiac cells modulate genetic programs, and deviations from normal stimuli can lead to cardiac defects. Therefore, it is important to characterize normal cardiac biomechanical stimuli during early developmental stages. Using the chicken embryo model of cardiac development, we focused on characterizing biomechanical stimuli on the HamburgerHamilton (HH) 18 chick cardiac outflow tract (OFT), the distal portion of the heart from which a large portion ...
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    11. Phase-sensitive optical coherence tomography characterization of pulse-induced trabecular meshwork displacement in ex vivo nonhuman primate eyes

      Phase-sensitive optical coherence tomography characterization of pulse-induced trabecular meshwork displacement in ex vivo nonhuman primate eyes
      Glaucoma is a blinding disease for which intraocular pressure (IOP) is the only treatable risk factor. The mean IOP is regulated through the aqueous outflow system, which contains the trabecular meshwork (TM). Considerable evidence indicates that trabecular tissue movement regulates the aqueous outflow and becomes abnormal during glaucoma; however, such motion has thus far escaped detection. The purpose of this study is to describe anovel use of a phase-sensitive optical ...
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    12. Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System

      Quantifying Optical Microangiography Images Obtained from a Spectral Domain Optical Coherence Tomography System
      The blood vessel morphology is known to correlate with several diseases, such as cancer, and is important for describing several tissue physiological processes, like angiogenesis. Therefore, a quantitative method for characterizing the angiography obtained from medical images would have several clinical applications. Optical microangiography (OMAG) is a method for obtaining three-dimensional images of blood vessels within a volume of tissue. In this study we propose to quantify OMAG images obtained ...
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    13. Feature Of The Week 6/17/12: Middle Ear Vibrometry of Human Cadaver Temporal Bone with Spectral Domain Phase-Sensitive Optical Coherence Tomography

      Feature Of The Week 6/17/12: Middle Ear Vibrometry of Human Cadaver Temporal Bone with Spectral Domain Phase-Sensitive Optical Coherence Tomography
      Hearing loss is the most frequent sensory deficit in the human population, affecting more than 250 million people in the world. The National Center for Health Statistics estimates that 37 million adults (17%) in the United States have hearing difficulty. Analysis of a large database of audiometric records from the University of Minnesota reveals that 39% of patients diagnosed with hearing loss have conductive hearing loss (CHL) either alone (15 ...
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    14. Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

      Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry
      We describe a novel application of spectral-domain phase-sensitive optical coherence tomography (SD PS-OCT) to detect the tiny motions of the middle ear structures, such as the tympanic membrane and ossicular chain, and their morphological features for differential diagnosis of CHL. This technique has the potential to provide meaningful vibration of ossicles with a vibration sensitivity of ∼ 0.5  nm at 1 kHz of acoustic stimulation. To the best of our ...
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    15. Feature Of The Week 5/27/11: Researchers Utilize Optical Coherence Tomography to Perform in vivo Investigation into the Process of Hearing

      Feature Of The Week 5/27/11: Researchers Utilize Optical Coherence Tomography to Perform in vivo Investigation into the Process of Hearing
      A multidisciplinary research groups spanning several countries (USA, China, Sweden) are using optical coherence tomography (OCT) to investigate minute changes in hair cells within the cochlea - the auditory portion of the inner ear. Below is a summary of their work. Mammalian hearing is refined by amplification of the sound-evoked vibration of the cochlear partition. This amplification is at least partly due to forces produced by protein motors residing in the ...
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    16. Noncontact all-optical measurement of corneal elasticity

      Noncontact all-optical measurement of corneal elasticity
      We report on a noninvasive and noncontact all-optical method to measure the elasticity of the cornea. We use a pulsed laser to excite surface acoustic waves (SAW) that propagate on the corneal surface, then use a phase-sensitive optical coherence tomography system to remotely record the SAWs from which the corneal elasticity is estimated. In addition, the system is able to provide real-time tomographic images of the cornea being examined, an ...
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    17. 241-255 of 328 « 1 2 ... 14 15 16 17 18 19 20 21 22 »
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  2. About University of Washington

    University of Washington

    The University of Washington, founded in 1861, is a public research university in Seattle, Washington, United States. It is the largest university in the Northwestern United States and the oldest public university in Washington. The UW maintains three locations, with its flagship campus in Seattle's University District and branch campuses in Tacoma and Bothell. Its operating budget for fiscal year 2005 was $3.1 billion. The university is known as a Public Ivy, an American term for state-funded institutions of higher learning that "provide[s] an Ivy League collegiate experience at a public school price."