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1. Mentioned In 348 Articles
2. Handheld swept-source optical coherence tomography with angiography in awake premature neonates
  
  Explore Home Oct 1 2019 Ophthalmology
  
  Background: Retinopathy of prematurity (ROP) can lead to retinal detachment and severe vision loss and is a common cause of childhood blindness. Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can be used to detect potential abnormalities in the microvasculature in this population. The objective of this study is to assess the feasibility of a newly developed handheld swept source OCT (SS-OCT) device to successfully acquire structural ...
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  Mentions: University of Washington Ruikang K. Wang
3. Correlations between Different Choriocapillaris Flow Deficit Parameters in Normal Eyes using Swept Source OCT Angiography
  
  Explore American Journal of Ophthalmology Sep 25 2019 Ophthalmology
  
  Purpose Choriocapillaris (CC) imaging of normal eyes with swept-source optical coherence tomography SS-OCTA was performed, and the percentage of CC flow deficits (FD%) and the average area of CC flow deficits (FDa) were compared within given macular regions. Design A prospective, cross-sectional study. Methods Subjects with normal eyes ranging in age from their 20s through their 80s were imaged with SS-OCTA (PLEX Elite 9000, Carl Zeiss Meditec, Dublin, CA) using ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
4. Spatial resolution in dynamic optical coherence elastography
  
  Explore SPIE Digital Library Sep 24 2019
  
  Dynamic optical coherence elastography (OCE) tracks elastic wave propagation speed within tissue, enabling quantitative three-dimensional imaging of the elastic modulus. We show that propagating mechanical waves are mode converted at interfaces, creating a finite region on the order of an acoustic wavelength where there is not a simple one-to-one correspondence between wave speed and elastic modulus. Depending on the details of a boundarys geometry and elasticity contrast, highly complex propagating ...
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  Mentions: University of Washington Ruikang K. Wang Chunhui Li
5. Two-Year Risk of Exudation in Eyes with Nonexudative Age-Related Macular Degeneration and Subclinical Neovascularization Detected with Swept Source Optical Coherence Tomography Angiography
  
  Explore American Journal of Ophthalmology Sep 22 2019 Ophthalmology
  
  Purpose Swept source optical coherence tomography angiography (SS-OCTA) was used to study the prevalence, incidence, and natural history of subclinical macular neovascularization (MNV) in eyes with unilateral nonexudative age-related macular degeneration. Design Prospective cohort study. Methods Patients were imaged using 3- 3-mm and 6- 6-mm SS-OCTA scan patterns. MNV was detected using the outer retina to choriocapillaris en face slab. Prevalence and incidence of subclinical MNV, KaplanMeier cumulative estimates for ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
6. Systems and methods for in vivo visualization of lymphatic vessels with optical coherence tomography
  
  Explore uspto.gov Sep 10 2019 Patents
  
  The present technology relates generally to systems and methods for in vivo visualization of lymphatic vessels. A system includes an optical coherence tomography (OCT) device and a computing device coupled to the OCT device configured to cause the OCT device to perform an OCT scan, generate image data in response to the OCT scan, and apply an eigendecomposition filter to the image data to produce processed image data. Alternatively or ...
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  Mentions: University of Washington Ruikang K. Wang
7. Quantifying choriocapillaris hypoperfusion in patients with choroidal neovascularization using swept-source OCT angiography
  
  Explore Medical Journals Publisher Aug 26 2019 Ophthalmology
  
  ...Department of Ophthalmology, University of California, San Francisco, CA, USA; 2Department of Bioengineering, University of Washington, Seattle, WA, USA; 3Francis I. Proctor Foundation, University of California, San Fran...
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  Mentions: University of Washington Ruikang K. Wang UCSF
8. Quantification of choriocapillaris with OCTA: a comparison study
  
  Explore American Journal of Ophthalmology Jul 16 2019 Ophthalmology
  
  Purpose To demonstrate the variation in quantitative choriocapillaris (CC) metrics with various binarization approaches using optical coherence tomography angiography (OCTA). Design Retrospective, observational, cross-sectional case series. Methods 3x3 mm and 6x6 mm macular OCTA scans were obtained from normal eyes and from eyes with drusen secondary to AMD. The CC slab was extracted and the CC flow deficits (FDs) were segmented with two previously published algorithms: fuzzy C-means approach (FCM ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
9. Systems and methods for quantitative assessment of microvasculature using optical coherence tomography angiography
  
  Explore uspto.gov Jul 16 2019 Patents
  
  A five-index quantitative analysis of OCT angiograms is disclosed. One method of analyzing an anatomical region of interest of a subject includes acquiring vascular image data from the region of interest and generating a binary vasculature map from the vascular image data. A vessel skeleton map and vessel perimeter map are generated from the binary vasculature map. Based on the three generated maps, a vessel area density, vessel skeleton density ...
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  Mentions: University of Washington Ruikang K. Wang
10. University of Washington Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy
  
  Explore Optical Coherence Tomography News Jul 2 2019 Ophthalmology , Funding
  
  ...neration of OCT angiography and for interpretation of UW-OMAG data in future.
  University of Washington Receives a 2019 NIH Grant for $364,428 for Ultra-Wide Field Optical Coherence Tomogra...
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  Mentions: University of Washington Ruikang K. Wang
11. Impaired Retinal Vascular Reactivity in Diabetic Retinopathy as Assessed by Optical Coherence Tomography Angiography
  
  Explore IOVS Journal Jun 25 2019 Ophthalmology
  
  Purpose : To assess retinal vascular reactivity in healthy controls and subjects with diabetic retinopathy (DR). Methods : A total of 22 healthy control eyes and 16 eyes with DR were enrolled. Images were acquired using a commercially available swept-source optical coherence tomography angiography (SS-OCTA) system. Three conditions were tested for each patient (hyperoxia, hypercapnia, and room-air) by employing a non-rebreathing apparatus that delivered appropriate gas mixtures (100% O 2 , 5% CO ...
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  Mentions: University of Southern California University of Washington Ruikang K. Wang
12. Two-Year Risk of Exudation in Eyes with Non-Exudative AMD and Subclinical Neovascularization Detected with Swept Source OCT Angiography
  
  Explore American Journal of Ophthalmology Jun 20 2019 Ophthalmology
  
  Purpose Swept source optical coherence tomography angiography (SS-OCTA) was used to study the prevalence, incidence, and natural history of subclinical macular neovascularization (MNV) in eyes with unilateral non-exudative age-related macular degeneration (AMD). Design Prospective cohort study. Methods Patients were imaged using 3x3 mm and 6x6 mm SS-OCTA scan patterns. MNV was detected using the outer retina to choriocapillaris en face slab. Prevalence and incidence of subclinical MNV, Kaplan-Meier cumulative estimates ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
13. Optical coherence tomography correlates multiple measures of tissue damage following acute burn injury
  
  Explore Home May 28 2019 Dermatology
  
  Background: The visual assessment of burned skin is inherently subjective, and whilst a number of imaging modalities have identified quantifiable parameters to characterize vascular and structural changes following burn damage, none have become common place in the assessment protocol. Here, we use optical coherence tomography (OCT)-based angiography (OCTA) to introduce novel correlations between vessel depth, i.e., the depth of functional blood vessels beneath the tissue surface, edema depth ...
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  Mentions: University of Washington Ruikang K. Wang
14. Revealing the morphology and function of the cochlea and middle ear with optical coherence tomography
  
  Explore Home May 28 2019 Otolaryngology
  
  Optical coherence tomography (OCT) has revolutionized physiological studies of the hearing organ, the vibration and morphology of which can now be measured without opening the surrounding bone. In this review, we provide an overview of OCT as used in the otological research, describing advances and different techniques in vibrometry, angiography, and structural imaging.
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  Mentions: Oregon Health & Science University University of Washington Ruikang K. Wang
15. Intravascular Ultrasound and Optical Coherence Tomography in the Procedural Planning and Execution of Left Main Coronary Artery Percutaneous Coronary Intervention
  
  Explore Home - Springer May 25 2019 Cardiology
  
  Purpose of Review Left main coronary artery disease (LMCAD) is a frequently encountered, high-risk presentation of atherosclerosis, traditionally managed with surgical bypass grafting. Percutaneous coronary intervention (PCI) for LMCAD is an increasingly attractive option for patients with low to intermediate complexity disease or patients at extremely high or prohibitive surgical risk. The goal of this review is to outline the current indications and guideline recommendations regarding PCI for LMCAD and ...
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  Mentions: University of Washington Peking University
16. Visualizing choriocapillaris using swept-source optical coherence tomography angiography with various probe beam sizes
  
  Explore OSA | OSA Publishing May 17 2019 Ophthalmology
  
  Imaging choriocapillaris (CC) is a long-term challenge for commercial OCT angiography (OCTA) systems due to limited transverse resolution. Effects of transverse resolution on the visualization of a CC microvascular network are explored and demonstrated in this paper. We use three probe beams with sizes of ~1.12 mm, ~2.51 mm and ~3.50 mm at the pupil plane, which deliver an estimated transverse resolution at the retina of 17 ...
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  Mentions: University of Washington Ruikang K. Wang University of Dundee
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