1. University of Washington

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    1. Mentioned In 272 Articles

    2. Automatic motion correction for in vivo human skin optical coherence tomography angiography through combined rigid and nonrigid registration

      Automatic motion correction for in vivo human skin optical coherence tomography angiography through combined rigid and nonrigid registration
      When using optical coherence tomography angiography (OCTA), the development of artifacts due to involuntary movements can severely compromise the visualization and subsequent quantitation of tissue microvasculatures. To correct such an occurrence, we propose a motion compensation method to eliminate artifacts from human skin OCTA by means of step-by-step rigid affine registration, rigid subpixel registration, and nonrigid B-spline registration. To accommodate this remedial process, OCTA is conducted using two matching all-depth ...
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    3. Optical coherence tomography angiography-based capillary velocimetry

      Optical coherence tomography angiography-based capillary velocimetry
      Challenge persists in the field of optical coherence tomography (OCT) when it is required to quantify capillary blood flow within tissue beds in vivo . We propose a useful approach to statistically estimate the mean capillary flow velocity using a model-based statistical method of eigendecomposition (ED) analysis of the complex OCT signals obtained with the OCT angiography (OCTA) scanning protocol. ED-based analysis is achieved by the covariance matrix of the ensemble ...
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    4. Spontaneous Coronary Artery Dissection: Insights From Histology and Optical Coherence Tomography

      Spontaneous Coronary Artery Dissection: Insights From Histology and Optical Coherence Tomography
      Spontaneous coronary artery dissection (SCAD) is a well-known but infrequent cause of acute coronary syndrome (ACS), and often goes unrecognized. Although management of SCAD is, at times, controversial, when a patient presents with ACS, percutaneous coronary intervention (PCI) is frequently necessary. We present a patient with ST-segment elevation myocardial infarction (STEMI) with SCAD that illustrates two important points: use of intracoronary optical coherence tomography to guide PCI, and histologic assessment ...
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    5. Robust numerical phase stabilization for long-range swept-source optical coherence tomography

      Robust numerical phase stabilization for long-range swept-source optical coherence tomography
      A novel phase stabilization technique is demonstrated with significant improvement in the phase stability of a micro-electromechanical (MEMS) vertical cavity surface-emitting laser (VCSEL) based swept-source optical coherence tomography (SS-OCT) system. Without any requirements of hardware modifications, the new fully numerical phase stabilization technique features high tolerance to acquisition jitter, and significantly reduced budget in computational effort. We demonstrate that when measured with biological tissue, this technique enables a phase sensitivity ...
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    6. Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy

      Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy
      Purpose: To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. Materials and Methods: A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM ...
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    7. Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography

      Imaging collector channel entrance with a new intraocular micro-probe swept-source optical coherence tomography
      Purpose To describe the use of a newly developed side-viewing catheter probe to provide the cross-sectional images of collector channel entrance (CCE), achieved by swept-source optical coherence tomography (SS-OCT). Methods A side-viewing SS-OCT catheter probe was developed that has a core probe diameter of 0.15 mm and an outer diameter of 0.25 mm, for the purpose of imaging CCEs within eye globe. Cadaver eyes harvested from swine and ...
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    8. Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography

      Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography
      Purpose To quantitatively evaluate the retinal microvasculature in human subjects with retinal venous occlusions (RVO) using optical coherence tomography angiography (OCTA). Design Retrospective, cross-sectional, observational case series. Participants Sixty subjects (84 eyes) were included (20 BRVO, 14 CRVO, 24 unaffected fellow eyes, and 26 controls). Methods OCTA was performed on a prototype, spectral domain-OCTA system in the 3x3mm central macular region. Custom software was used to quantify morphology and density ...
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    9. OHSU Receives NIH Grant for Studies in Glaucomatous Optic Nerve Damage

      OHSU Receives NIH Grant  for Studies in Glaucomatous Optic Nerve Damage
      ... and ONH perfusion with Doppler-Optical Coherence Tomography, adapted for rat eyes by Dr. Ruikang Wang at the University of Washington. Specific Aim 3 will demonstrate that inhibition of the Jak2/Stat3 pathway, an initia...
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    10. Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization

      Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
      Purpose : The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). Methods : Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 3- and 6 6-mm 2 scans were obtained on both instruments. The 3 3-mm 2 SS-OCTA scans consisted of 300 A-scans per ...
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    11. Deep Learning Is Effective for Classifying Normal versus Age-Related Macular Degeneration Optical Coherence Tomography Images

      Deep Learning Is Effective for Classifying Normal versus Age-Related Macular Degeneration Optical Coherence Tomography Images
      Purpose The advent of electronic medical records (EMRs) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image analysis. Optical coherence tomography (OCT) is the most common imaging modality in ophthalmology and represents a dense and rich data set when combined with labels derived from the EMR. We sought to determine whether deep learning ...
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    12. Ultralong-range optical coherence tomography-based angiography by akinetic swept source

      Ultralong-range optical coherence tomography-based angiography by akinetic swept source
      Most of current OCT-based angiography suffers from small FOV with short imaging range. Here we implement an ultralong-range OCT system for vascular imaging based on an akinetic swept source. This swept-source OCT (SS-OCT) system enables us to achieve up to 46 mm long imaging range with unprecedented roll-off performance. To compare with traditional spectral domain OCT (SD-OCT) system, we demonstrated the vascular imaging of the entire mice brain with wide ...
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    13. Non-contact rapid optical coherence elastography by high-speed 4D imaging of elastic waves

      Non-contact rapid optical coherence elastography by high-speed 4D imaging of elastic waves
      Shear wave OCE (SW-OCE) uses an OCT system to track propagating mechanical waves, providing the information needed to map the elasticity of the target sample. In this study we demonstrate high speed, 4D imaging to capture transient mechanical wave propagation. Using a high-speed Fourier domain mode-locked (FDML) swept-source OCT (SS-OCT) system operating at ~1.62 MHz A-line rate, the equivalent volume rate of mechanical wave imaging is 16 kvps (kilo-volumes ...
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    14. Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy

      Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy
      PURPOSE To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM ...
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    15. 1-15 of 272 1 2 3 4 ... 16 17 18 »
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  2. About University of Washington

    University of Washington

    The University of Washington, founded in 1861, is a public research university in Seattle, Washington, United States. It is the largest university in the Northwestern United States and the oldest public university in Washington. The UW maintains three locations, with its flagship campus in Seattle's University District and branch campuses in Tacoma and Bothell. Its operating budget for fiscal year 2005 was $3.1 billion. The university is known as a Public Ivy, an American term for state-funded institutions of higher learning that "provide[s] an Ivy League collegiate experience at a public school price."