1. University of Washington

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    1. Mentioned In 207 Articles

    2. Minimally invasive surgical method to detect sound processing in the cochlear apex by optical coherence tomography

      Minimally invasive surgical method to detect sound processing in the cochlear apex by optical coherence tomography
      Sound processing in the inner ear involves separation of the constituent frequencies along the length of the cochlea. Frequencies relevant to human speech (100 to 500 Hz) are processed in the apex region. Among mammals, the guinea pig cochlear apex processes similar frequencies and is thus relevant for the study of speech processing in the cochlea. However, the requirement for extensive surgery has challenged the optical accessibility of this area ...
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    3. Review of optical coherence tomography based angiography in neuroscience

      Review of optical coherence tomography based angiography in neuroscience
      The brain is a complex ecosystem, consisting of multiple layers and tissue compartments. To facilitate the understanding of its function and its response to neurological insults, a fast in vivo imaging tool with a micron-level resolution, which can provide a field of view at a few millimeters, is desirable. Optical coherence tomography (OCT) is a noninvasive method for imaging three-dimensional biological tissues with high resolution ( 10 m 10m ) and without ...
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    4. Development of a phase-sensitive Fourier domain optical coherence tomography system to measure mouse organ of Corti vibrations in two cochlear turns

      Development of a phase-sensitive Fourier domain optical coherence tomography system to measure mouse organ of Corti vibrations in two cochlear turns
      In this study, we have developed a phase-sensitive Fourier-domain optical coherence tomography system to simultaneously measure the in vivo inner ear vibrations in the hook area and second turn of the mouse cochlea. This technical development will enable measurement of intra-cochlear distortion products at ideal locations such as the distortion product generation site and reflection site. This information is necessary to un-mix the complex mixture of intra-cochlear waves comprising the ...
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    5. Multifunctional 1050 nm Spectral Domain OCT System at 147 kHz for Posterior Eye Imaging

      Multifunctional 1050 nm Spectral Domain OCT System at 147 kHz for Posterior Eye Imaging
      The recent development of optical coherence tomography in ophthalmology has shown great interests in using the system in 1 m in contrast to 800 nm wavelength range due to the less reflection and absorption of retinal pigment epithelium and pigmented choroidal melanocytes in 1 m wavelength. The clinical value of using 1 m system has been demonstrated in choroid imaging, retinal and choroidal microcirculation, etc. By examining different aspects of ...
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    6. Moving beam shear wave reconstruction for both ultrasound and optical coherence tomography applications

      Moving beam shear wave reconstruction for both ultrasound and optical coherence tomography applications
      Shear wave elasticity imaging can quantitatively estimate a stiffness map of biological tissues based on speckle-tracking shear wave propagation. However, current approaches cannot directly reconstruct elasticity properties in speckle-less or speckle-free regions, for example within the crystalline lens in ophthalmology. We propose an imaging sequence to reconstruct the elastic properties in speckle-free regions by sequentially launching shear waves with a laterally moving acoustic radiation force, and then detecting the displacement ...
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    7. Non-destructive evaluation of an internal adaptation of resin composite restoration with swept-source optical coherence tomography and micro-CT

      Non-destructive evaluation of an internal adaptation of resin composite restoration with swept-source optical coherence tomography and micro-CT
      Swept-source optical coherence tomography (SS-OCT) and micro-CT can be useful non-destructive methods for evaluating internal adaptation. There is no comparative study evaluating the two methods in the assessment of internal adaptation in composite restoration. The purpose of this study was to compare internal adaptation measurements of SS-OCT and micro-CT. Two cylindrical cavities were created on the labial surface of twelve bovine incisors. The 24 cavities were randomly assigned to four ...
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    8. Quantitative shear-wave optical coherence elastography with a programmable phased array ultrasound as the wave source

      Quantitative shear-wave optical coherence elastography with a programmable phased array ultrasound as the wave source
      The purpose of this study is to implement a beam-steering ultrasound as the wave source for shear-wave optical coherence elastography (SW-OCE) to achieve an extended range of elastic imaging of the tissue sample. We introduce a linear phased array ultrasound transducer (LPAUT) as the remote and programmable wave source and a phase-sensitive optical coherence tomography (OCT) as the sensitive shear-wave detector. The LPAUT is programmed to launch acoustic radiation force ...
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    9. In vivo assessment of wall strain in embryonic chick heart by spectral domain optical coherence tomography

      In vivo assessment of wall strain in embryonic chick heart by spectral domain optical coherence tomography
      The ability to measurein vivowall strain in embryonic hearts is important for fully understanding the mechanisms of cardiac development. Optical coherence tomography (OCT) is a powerful tool for the three-dimensional imaging of complex myocardial activities in early-stage embryonic hearts with high spatial and temporal resolutions. We describe a method to analyze periodic deformations of myocardial walls and evaluatein vivomyocardial wall strains with a high-speed spectral domain OCT system. We perform ...
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    10. Monitoring disposition of tethered capsule endoscope in esophagus

      Monitoring disposition of tethered capsule endoscope in esophagus
      A scanning flexible endoscope includes a tether attached to a capsule. The tether controls a disposition of the capsule within a body lumen such as the esophagus. A scanning device in the capsule optically scans the adjacent tissue on the inside surface of the body lumen as the capsule is moved axially through the body lumen. A non-contact sensor responds to indicia on the tether to measure a relative position ...
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    11. Methods and algorithms for optical coherence tomography-based angiography: a review and comparison

      Methods and algorithms for optical coherence tomography-based angiography: a review and comparison
      Optical coherence tomography (OCT)-based angiography is increasingly becoming a clinically useful and important imaging technique due to its ability to provide volumetric microvascular networks innervating tissue beds in vivo without a need for exogenous contrast agent. Numerous OCT angiography algorithms have recently been proposed for the purpose of contrasting microvascular networks. A general literature review is provided on the recent progress of OCT angiography methods and algorithms. The basic ...
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    12. SWEPT SOURCE OCT ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2

      SWEPT SOURCE OCT ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2
      Background/Purpose: To image subretinal neovascularization in proliferative macular telangiectasia Type 2 (MacTel2) using swept source optical coherence tomography based microangiography (OMAG). Methods: Patients with macular telangiectasia Type 2 were enrolled in a prospective, observational study known as the MacTel Project and evaluated using a high-speed 1,050 nm swept-source OCT prototype system. The OMAG algorithm generated en face flow images from three retinal layers, and the region bounded by ...
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    13. Swept-source optical coherence tomography powered by a 1.3-μm vertical cavity surface emitting laser enables 2.3-mm-deep brain imaging in mice in vivo

      Swept-source optical coherence tomography powered by a 1.3-μm vertical cavity surface emitting laser enables 2.3-mm-deep brain imaging in mice in vivo
      We report noninvasive, in vivo optical imaging deep within a mouse brain by swept-source optical coherence tomography (SS-OCT), enabled by a 1.3 - m vertical cavity surface emitting laser (VCSEL). VCSEL SS-OCT offers a constant signal sensitivity of 105 dB throughout an entire depth of 4.25 mm in air, ensuring an extended usable imaging depth range of more than 2 mm in turbid biological tissue. Using this approach, we ...
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    14. Ophthalmic Application of Optical Coherence Tomography Based Angiography for Choroidal Imaging (Thesis)

      Ophthalmic Application of Optical Coherence Tomography Based Angiography for Choroidal Imaging (Thesis)
      We demonstrated in vivo choriocapillaris imaging in normal human subjects with a Cirrus HD 5000 spectral domain OCT prototype. With the tracking system installed in the prototype and the montage scanning protocol, wide field OCT angiograms of 9 mm * 11 mm were created. OCT angiography utilizes the intrinsic motion of red blood cells as contrast mechanism therefore requires no exogenous contrast agents as fluorescein angiography and indocyanine green angiography do ...
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    15. 1-15 of 207 1 2 3 4 ... 12 13 14 »
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  2. About University of Washington

    University of Washington

    The University of Washington, founded in 1861, is a public research university in Seattle, Washington, United States. It is the largest university in the Northwestern United States and the oldest public university in Washington. The UW maintains three locations, with its flagship campus in Seattle's University District and branch campuses in Tacoma and Bothell. Its operating budget for fiscal year 2005 was $3.1 billion. The university is known as a Public Ivy, an American term for state-funded institutions of higher learning that "provide[s] an Ivy League collegiate experience at a public school price."