1. University of Washington

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    1. Mentioned In 428 Articles

    2. Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits

      Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits
      The purpose of this study is to quantitatively assess correlations between local geographic atrophy (GA) growth rates and local optical coherence tomography angiography (OCTA)-measured choriocapillaris (CC) flow deficits. Thirty-eight eyes from 27 patients with GA secondary to age-related macular degeneration (AMD) were imaged with a commercial 1050 nm swept-source OCTA instrument at 3 visits, each separated by 6 months. Pearson correlations were computed between local GA growth rates, estimated ...
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    3. Gingivitis resolution followed by optical coherence tomography and fluorescence imaging: a case study

      Gingivitis resolution followed by optical coherence tomography and fluorescence imaging: a case study
      Gingivitis is highly prevalent in adults, and if left untreated, can progress to periodontitis. In this paper, we present an interesting case study where the resolution of gingivitis was followed over a period of 10 days using optical coherence tomography (OCT) and light-induced autofluorescence (LIAF). We demonstrate that OCT and its functional angiography can distinctively capture the changes during the resolution of gingivitis; whilst LIAF can detect red-fluorescent signals associated ...
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    4. Student becomes teacher: training faster deep learning lightweight networks for automated identification of optical coherence tomography B-scans of interest using a student-teacher framework

      Student becomes teacher: training faster deep learning lightweight networks for automated identification of optical coherence tomography B-scans of interest using a student-teacher framework
      This work explores a student-teacher framework that leverages unlabeled images to train lightweight deep learning models with fewer parameters to perform fast automated detection of optical coherence tomography B-scans of interest. Twenty-seven lightweight models (LWMs) from four families of models were trained on expert-labeled B-scans (70 K) as either abnormal or normal, which established a baseline performance for the models. Then the LWMs were trained from random initialization using a ...
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    5. Optical Coherence Tomography Angiography-Derived Flux As a Measure of Physiological Changes in Retinal Capillary Blood Flow

      Optical Coherence Tomography Angiography-Derived Flux As a Measure of Physiological Changes in Retinal Capillary Blood Flow
      Purpose: To compare optical coherence tomography angiography (OCTA)-derived flux with conventional OCTA measures of retinal vascular density in assessment of physiological changes in retinal blood flow. Methods: Healthy subjects were recruited, and 3 3-mm2 fovea-centered scans were acquired using commercially available swept-source OCTA (SS-OCTA) while participants were breathing room air, 100% O2, or 5% CO2. Retinal perfusion was quantified using vessel area density (VAD) and vessel skeleton density (VSD ...
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    6. Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography

      Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography
      The choroid provides nutritional support for the retinal pigment epithelium and photoreceptors. Choroidal dysfunction plays a major role in several of the most important causes of vision loss including age-related macular degeneration, myopic degeneration, and pachychoroid diseases such as central serous chorioretinopathy and polypoidal choroidal vasculopathy. We describe an imaging technique using depth-resolved swept-source optical coherence tomography (SS-OCT) that provides full-thickness three-dimensional (3D) visualization of choroidal anatomy including topographical features ...
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    7. The disposable bandage soft contact lenses therapy and anterior segment optical coherence tomography for management of ocular graft-versus-host disease

      The disposable bandage soft contact lenses therapy and anterior segment optical coherence tomography for management of ocular graft-versus-host disease
      Purpose: To identify the ocular surface changes of ocular graft-versus-host disease (GVHD) using anterior segment optical coherence tomography (AS-OCT) and examine the efficacy of disposable bandage soft contact lens (BSCL) treatment in ocular GVHD patients. Methods: This study is a prospective, Phase II clinical trial. Nineteen patients diagnosed with chronic GVHD based on the NIH criteria and ocular symptoms of NIH eye score 2 or greater were enrolled. Disposable BSCL ...
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    8. Washington University Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy

      Washington University Receives NIH Grant for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy
      Washington University Receives a 2021 NIH Grant for $558,926 for Ultra-Wide Field Optical Coherence Tomography Based Angiography for Imaging Diabetic Retinopathy. The principal investigator is Ruikang Wang. Below is a summary of the proposed work. The increasing incidence of diabetes in the US population and the inertial wave of aging in Americans will ensure that diabetic retinopathy (DR) remains one of the principal threats to the sight of adult ...
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    9. Delineating corneal elastic anisotropy in a porcine model using non-contact optical coherence elastography and ex vivo mechanical tests

      Delineating corneal elastic anisotropy in a porcine model using non-contact optical coherence elastography and ex vivo mechanical tests
      Objective : To compare non - contact acoustic micro - tapping optical coherence elastography ( AT - OCE ) with destructive mechanical tests to confirm corneal elastic anisotropy. Design : Ex vivo, laboratory study with non - contact AT - OCE followed by mechanical rheometry and extensometry . Subjects: Infl ated cornea of whole - globe porcine eyes ( n =9). Methods: A non - contact AT transducer was used to launch propagating mechanical waves in the cornea that were imaged with phase ...
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    10. Assessing the Clinical Utility of Expanded Macular OCTs Using Machine Learning

      Assessing the Clinical Utility of Expanded Macular OCTs Using Machine Learning
      Purpose: Optical coherence tomography (OCT) is widely used in the management of retinal pathologies, including age-related macular degeneration (AMD), diabetic macular edema (DME), and primary open-angle glaucoma (POAG). We used machine learning techniques to understand diagnostic performance gains from expanding macular OCT B-scans compared with foveal-only OCT B-scans for these conditions. Methods: Electronic medical records were extracted to obtain 61 B-scans per eye from patients with AMD, diabetic retinopathy, or ...
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    11. Steps to Measurement Floor of an Optical Microangiography Device in Glaucoma

      Steps to Measurement Floor of an Optical Microangiography Device in Glaucoma
      Purpose To compare dynamic ranges and steps to measurement floors of peripapillary and macular metrics from a complex signal-based optical microangiography (OMAG C ) optical coherence tomography angiography (OCTA) device for glaucoma with those of OCT measurements. Design Cross-sectional study. Methods Imaging of 252 eyes from 173 glaucoma subjects and 123 eyes from 92 non-glaucoma subjects from a glaucoma clinic was quantified using custom and commercial software. Metrics from OCT (retinal ...
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    12. Application of OCT-Derived Attenuation Coefficient in Acute Burn-Damaged Skin

      Application of OCT-Derived Attenuation Coefficient in Acute Burn-Damaged Skin
      Background and objectives: There remains a need to objectively monitor burn wound healing within a clinical setting, and optical coherence tomography (OCT) is proving itself one of the ideal modalities for just such a use. The aim of this study is to utilize the noninvasive and multipurpose capabilities of OCT, along with its cellular-level resolution, to demonstrate the application of optical attenuation coefficient (OAC), as derived from OCT data, to ...
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    13. Swept-Source OCT Angiographic Characteristics of Treatment-Naïve Nonexudative Macular Neovascularization in AMD Prior to Exudation

      Swept-Source OCT Angiographic Characteristics of Treatment-Naïve Nonexudative Macular Neovascularization in AMD Prior to Exudation
      Purpose: To investigate the characteristics of treatment-nave nonexudative macular neovascularization (MNV) in age-related macular degeneration before the onset of exudation using swept-source optical coherence tomography angiography. Methods: MNV area, choriocapillaris (CC) flow deficits (FDs), vessel area density (VAD), vessel skeleton density (VSD), retinal pigment epithelial detachment (PED) volume, mean choroidal thickness (MCT), and choroid vascularity index (CVI) measurements were assessed at two visits prior to exudation. We compared measurements made ...
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    14. Super-Achromatic Rapid Scanning Microendoscope for Ultrahigh-Resolution OCT Imaging

      Super-Achromatic Rapid Scanning Microendoscope for Ultrahigh-Resolution OCT Imaging
      Microendoscope is a critical technology to enable high-resolution imaging of internal luminal organs with optical coherence tomography. This paper reports the development of an achromatic compound microlens and a rapid scanning microendoscope based on the microlens that offers an ultrahigh transverse resolution of 4 mum (and an axial resolution of 2.2 mum when using a low-coherence light source with a broad spectrum bandwidth of 150 nm). The rapid scanning ...
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    15. 4-D Imaging of Beating Tissues using Optical Coherence Tomography

      4-D Imaging of Beating Tissues using Optical Coherence Tomography
      An imaging technique which reconstructs structure and flow in tissue with repetitive motion was developed using Optical Coherence Tomography (OCT). The demonstrated technique is able to accurately image both host tissue and flow at different time points during a cyclic motion, such as a cardiac cycle. Using tissue-mimicking phantoms, a phase-sensitive spectral-domain OCT system was combined with a cyclic-motion simulator to demonstrate the feasibility of the method. 3-D flow information ...
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    16. 1-15 of 428 1 2 3 4 ... 27 28 29 »
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  2. About University of Washington

    University of Washington

    The University of Washington, founded in 1861, is a public research university in Seattle, Washington, United States. It is the largest university in the Northwestern United States and the oldest public university in Washington. The UW maintains three locations, with its flagship campus in Seattle's University District and branch campuses in Tacoma and Bothell. Its operating budget for fiscal year 2005 was $3.1 billion. The university is known as a Public Ivy, an American term for state-funded institutions of higher learning that "provide[s] an Ivy League collegiate experience at a public school price."