1. University of Washington

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    1. Mentioned In 445 Articles

    2. Valve-Like Outflow System Behavior With Motion Slowing in Glaucoma Eyes: Findings Using a Minimally Invasive Glaucoma Surgery-MIGS-Like Platform and Optical Coherence Tomography Imaging

      Explore Frontiers Ophthalmology
      Valve-Like Outflow System Behavior With Motion Slowing in Glaucoma Eyes: Findings Using a Minimally Invasive Glaucoma Surgery-MIGS-Like Platform and Optical Coherence Tomography Imaging
      Purpose: This study aimed to investigate anatomic relationships and biomechanics of pressure-dependent trabecular meshwork and distal valve-like structure deformation in normal and glaucoma eyes using high-resolution optical coherence tomography (HR-OCT). Methods: We controlled Schlemm's canal (SC) pressure during imaging with HR-OCT in segments of three normal (NL) and five glaucomatous (GL) ex vivo eyes. The dissected limbal wedges were studied from 15 locations (5 NL and 10 GL). A ...
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      Mentions: Duke University University of Washington Indiana University

    3. Mitigating the effects of choroidal hyper- and hypo-transmission defects on choroidal vascularity index assessments using optical coherence tomography

      Explore Home Ophthalmology
      Mitigating the effects of choroidal hyper- and hypo-transmission defects on choroidal vascularity index assessments using optical coherence tomography
      Background: Changes in choroidal vascularity index (CVI) are associated with multiple choroid-related ocular diseases. CVI is calculated as the area/volume ratio of vessels in the choroid, which could be affected by alterations in regional signal intensities due to hypo-transmission defects (hypoTDs) caused by drusen and retinal pigment epithelium (RPE) detachments, and hyper-transmission defects (hyperTDs) caused by the absence of RPE. To develop a simulation model to verify the CVI ...
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      Mentions: University of Washington University of Miami

    4. Swept-Source Optical Coherence Tomography Detection of Bruch’s Membrane and Choriocapillaris Abnormalities in Sorsby Macular Dystrophy

      Explore LWW Online Ophthalmology
      Swept-Source Optical Coherence Tomography Detection of Bruch’s Membrane and Choriocapillaris Abnormalities in Sorsby Macular Dystrophy
      Purpose: Swept-source optical coherence tomography angiography (SS-OCTA) was used to analyze Bruch's membrane (BM) and choriocapillaris (CC) abnormalities in undiagnosed family members with Sorsby macular dystrophy (SMD). Methods: In a family with SMD (TIMP3 Tyr191Cys), SS-OCTA imaging was performed using the 6X6mm scan patter and previously validated algorithms to detect abnormalities in BM and the CC, as well as the presence of reticular pseudodrusen (RPD) and macular neovascularization (MNV ...
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      Mentions: University of Washington University of Miami

    5. Imaging-photoplethysmography-guided optical microangiography

      Explore Optica Publishing Group Dermatology
      Imaging-photoplethysmography-guided optical microangiography
      We report a method to image facial cutaneous microvascular perfusion using wide-field imaging photoplethysmography (iPPG) and handheld swept-source optical coherence tomography (OCT). The iPPG system employs a 16-bit-depth camera to provide a 2D wide-field blood pulsation map that is then used as a positioning guidance for OCT imaging of cutaneous microvasculature. We show the results from iPPG and OCT to demonstrate the ability of guided imaging of cutaneous microvasculature, which ...
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      Mentions: University of Washington

    6. Automatic geographic atrophy segmentation using optical attenuation in OCT scans with deep learning

      Explore Optica Publishing Group Ophthalmology
      Automatic geographic atrophy segmentation using optical attenuation in OCT scans with deep learning
      A deep learning algorithm was developed to automatically identify, segment, and quantify geographic atrophy (GA) based on optical attenuation coefficients (OACs) calculated from optical coherence tomography (OCT) datasets. Normal eyes and eyes with GA secondary to age-related macular degeneration were imaged with swept-source OCT using 66 mm scanning patterns. OACs calculated from OCT scans were used to generate customized composite en face OAC images. GA lesions were identified and measured ...
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      Mentions: University of Washington Carl Zeiss Meditec University of Miami

    7. Probing elastic anisotropy of human skin in vivo with light using non-contact acoustic micro-tapping OCE and polarization sensitive OCT

      Explore Nature Publishing Group Dermatology
      Probing elastic anisotropy of human skin in vivo with light using non-contact acoustic micro-tapping OCE and polarization sensitive OCT
      Skin broadly protects the human body from undesired factors such as ultraviolet radiation and abrasion and helps conserve body temperature and hydration. Skins elasticity and its level of anisotropy are key to its aesthetics and function. Currently, however, treatment success is often speculative and subjective, and is rarely based on skins elastic properties because there is no fast and accurate non-contact method for imaging of skins elasticity.
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      Mentions: University of Washington

    8. Policy-Driven, Multimodal Deep Learning for Predicting Visual Fields from the Optic Disc and Optical Coherence Tomography Imaging

      Explore Ophthalmology Ophthalmology
      Policy-Driven, Multimodal Deep Learning for Predicting Visual Fields from the Optic Disc and Optical Coherence Tomography Imaging
      Purpose To develop and validate a deep learning (DL) system for predicting each point on visual fields (VF) from disc and optical coherence tomography (OCT) imaging and derive a structure-function mapping. Design Retrospective, cross-sectional database study Participants 6437 patients undergoing routine care for glaucoma in three clinical sites in the UK. Methods OCT and infrared reflectance (IR) optic disc imaging was paired with the closest VF within 7 days. Efficient-Net ...
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      Mentions: University of London University of Washington

    10. OCTA Derived Vessel Skeleton Density Versus Flux and Their Associations With Systemic Determinants of Health

      Explore IOVS Journal Ophthalmology
      OCTA Derived Vessel Skeleton Density Versus Flux and Their Associations With Systemic Determinants of Health
      Purpose: To examine the associations of optical coherence tomography angiography (OCTA)-derived retinal capillary flux with systemic determinants of health. Methods: This is a cross-sectional study of subjects recruited from the African American Eye Disease Study. A commercially available swept-source (SS)-OCTA device was used to image the central 3 3 mm macular region. Retinal capillary perfusion was assessed using vessel skeleton density (VSD) and flux. Flux approximates the number ...
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      Mentions: Johns Hopkins University University of Southern California University of Washington

    11. Mitochondrial distribution in the outer plexiform layer of human retina - Does it correlate with reflectivity in OCT?

      Explore JOV Journal Ophthalmology
      Mitochondrial distribution in the outer plexiform layer of human retina - Does it correlate with reflectivity in OCT?
      Mitochondria are organelles essential for cellular metabolism that also contribute reflectivity to optical coherence tomography (OCT) via Mie scattering. To find reflectivity sources, we assessed mitochondrial distribution of outer plexiform layer (OPL) using comprehensive volume electron microscopy. Parafoveal retina of a 21-year-old male donor was subject to serial block-face scanning electron microscopy in 5550 nm voxels. A convolutional neural network (U-Net) was used to train and generate a deep learning ...
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      Mentions: University of Alabama University of Washington

    12. Device, method, and program for visualizing network of blood vessels of skin

      Explore uspto.gov Dermatology , Patents
      Device, method, and program for visualizing network of blood vessels of skin
      A device of an embodiment includes: an optical mechanism that guides light from a light source to skin tissue to scan the skin tissue; a control computation unit that controls driving of the optical mechanism, acquires tomographic images of the skin by processing optical interference signals from the optical system, and calculates a network of blood vessels on the basis of the tomographic images; and a display device that displays ...
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      Mentions: University of Washington Shiseido

    13. Capillary density and caliber as assessed by optical coherence tomography angiography may be significant predictors of diabetic retinopathy severity

      Explore Journals | PLOS Ophthalmology
      Capillary density and caliber as assessed by optical coherence tomography angiography may be significant predictors of diabetic retinopathy severity
      Purpose To validate retinal capillary density and caliber associations with diabetic retinopathy (DR) severity in different clinical settings. Methods This cross-sectional study assessed retinal capillary density and caliber in the superficial retinal layer of 3-mm OCTA scans centered on the fovea. Images were collected from non-diabetic controls and subjects with mild or referable DR (defined DR worse than mild DR) between February 2016 and December 2019 at secondary and tertiary ...
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      Mentions: Johns Hopkins University National Institutes of Health University of Southern California

    14. Interocular asymmetry of choroidal thickness and vascularity index measurements in normal eyes assessed by swept-source optical coherence tomography

      Explore Home Ophthalmology
      Interocular asymmetry of choroidal thickness and vascularity index measurements in normal eyes assessed by swept-source optical coherence tomography
      Background: To investigate the symmetry of interocular choroidal thickness and vascularity index measurements in normal eyes using swept-source optical coherence tomography (SS-OCT). Cross-sectional and observational study. This study included 244 eyes of 122 normal adults with ages uniformly distributed from 19 to 89 years. Methods: SS-OCT imaging was performed using a scanning pattern of 1212 mm. Mean choroidal thickness (MCT) and choroidal vascularity index (CVI) measurements in the entire scanning ...
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      Mentions: University of Washington University of Miami

    15. Optical Coherence Tomography for Patients with Developmental Disabilities: A Preliminary Study

      Explore MDPI Open Access Journals Platform Dentistry
      Optical Coherence Tomography for Patients with Developmental Disabilities: A Preliminary Study
      Dental radiographs are essential for diagnosis and treatment planning, but are sometimes difficult to acquire for patients with developmental disabilities (PDD). Optical Coherence Tomography (OCT) is a non-ionizing imaging modality that has the potential application as an alternative to dental radiographs for PDD. This study aimed to determine the feasibility of intraoral OCT imaging for PDD. Ten participants were recruited in the Dental Education in the Care of Persons with ...
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      Mentions: University of Washington Tokyo Medical & Dental University Yoshida Dental

    16. Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography

      Explore IOVS Journal Ophthalmology
      Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography
      Purpose: Swept-source optical coherence tomography angiography was used to investigate choroidal changes and their association with pigment epithelial detachments (PEDs) in eyes with polypoidal choroidal vasculopathy (PCV) after treatment with vascular endothelial growth factor (VEGF) inhibitors. Methods: Patients with treatment-nave PCV were included and underwent anti-VEGF therapy. Mean choroidal thickness (MCT), choroidal vascularity index (CVI), and PED volume measurements were obtained before and after treatment. Results: Thirty-four treatment-nave PCV eyes ...
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      Mentions: University of Washington University of Miami Shanghai Jiao Tong University
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  4. About University of Washington

    University of Washington

    The University of Washington, founded in 1861, is a public research university in Seattle, Washington, United States. It is the largest university in the Northwestern United States and the oldest public university in Washington. The UW maintains three locations, with its flagship campus in Seattle's University District and branch campuses in Tacoma and Bothell. Its operating budget for fiscal year 2005 was $3.1 billion. The university is known as a Public Ivy, an American term for state-funded institutions of higher learning that "provide[s] an Ivy League collegiate experience at a public school price."

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