1. University of Vienna

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    1. Mentioned In 34 Articles

    2. OCT Meets micro-CT: A Subject-Specific Correlative Multimodal Imaging Workflow for Early Chick Heart Development Modeling

      OCT Meets micro-CT: A Subject-Specific Correlative Multimodal Imaging Workflow for Early Chick Heart Development Modeling
      Structural and Doppler velocity data collected from optical coherence tomography have already provided crucial insights into cardiac morphogenesis. X-ray microtomography and other ex vivo methods have elucidated structural details of developing hearts. However, by itself, no single imaging modality can provide comprehensive information allowing to fully decipher the inner workings of an entire developing organ. Hence, we introduce a specimen-specific correlative multimodal imaging workflow combining OCT and micro-CT imaging which ...
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    3. Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography

      Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography
      Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a methionine choline-deficient (MCD)-diet model, and two mice fed the MCD diet for 1 and 2 weeks are involved in addition to a normal-diet mouse. The dynamic OCT is based on repeating raster scan and logarithmic intensity variance (LIV) analysis that enables volumetric metabolic ...
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    4. A Quantitative Model for Optical Coherence Tomography

      A Quantitative Model for Optical Coherence Tomography
      Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5, 6] certain simplifying assumptions are made for the reconstructions, but for many applications a more realistic description of the OCT imaging process is of interest. In mathematical models, for example, the incident angle of light onto the sample is ...
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    5. Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT

      Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT
      Subretinal fibrosis is one of the most prevalent causes of blindness in the elderly population, but a true gold standard to objectively diagnose fibrosis is still lacking. Since fibrotic tissue is birefringent, it can be detected by polarization-sensitive optical coherence tomography (PS-OCT). We present a new algorithm to automatically detect, segment, and quantify fibrotic lesions within 3D data sets recorded by PS-OCT. The algorithm first compensates for the birefringence of ...
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    6. SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED: Using a Novel Deep-Learning-Assisted Approach for Image Registration

      SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED: Using a Novel Deep-Learning-Assisted Approach for Image Registration
      Purpose: To compare area measurements between swept source optical coherence tomography angiography ( SSOCTA ), fluorescein angiography ( FA ), and indocyanine green angiography ( ICGA ) after applying a novel deep-learning-assisted algorithm for accurate image registration. Methods: We applied an algorithm for the segmentation of blood vessels in FA , ICGA , and SSOCTA images of 24 eyes with treatment-naive neovascular age-related macular degeneration. We trained a model based on U-Net and Mask R-CNN for each imaging ...
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    7. Absolute depth LIBS-stratigraphy with NoScSiSp-OCT

      Absolute depth LIBS-stratigraphy with NoScSiSp-OCT
      LIBS is a proven method for elemental analysis. It needs little to no sample preparation and relies solely on optical access to the sample. LIBS has therefore been handled as a promising analytical method for layered or structured samples with the potential to replace metallurgic cross-sections followed by SEM/EDX raster screenings. Due to the strong dependency of the ablation process on changing crater geometries, laser fluence, and plasma dynamics ...
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    8. Optical coherence tomography (OCT) to image active and inactive retinoblastomas as well as retinomas

      Optical coherence tomography (OCT) to image active and inactive retinoblastomas as well as retinomas
      Purpose To illustrate Optical Coherence Tomography (OCT) images of active and inactive retinoblastoma (Rb) tumours. Methods Current observational study included patients diagnosed with retinoblastoma and retinoma who were presented at Amsterdam UMC and Jules‐Gonin Eye Hospital, between November 2010 and October 2017. Patients aged between 0 and 4 years were imaged under general anaesthesia with handheld OCT in supine position. Patients older than 4 years were imaged with the ...
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    9. The inverse scattering problem for orthotropic media in polarization-sensitive optical coherence tomography

      The inverse scattering problem for orthotropic media in polarization-sensitive optical coherence tomography
      In this paper we provide for a first time, to our knowledge, a mathematical model for imaging an anisotropic, orthotropic medium with polarization-sensitive optical coherence tomography. The imaging problem is formulated as an inverse scattering problem in three dimensions for reconstructing the electrical susceptibility of the medium using Maxwells equations. Our reconstruction method is based on the second-order Born-approximation of the electric field
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    10. PhD Student Opening in Functional Optical Imaging Employing Contrast Agents at the Medical University of Vienna

      PhD Student Opening in Functional Optical Imaging Employing Contrast Agents at the Medical University of Vienna
      ...cking. The position is guaranteed of funding for 3 years. The student will work for two years at the Medical University of Vienna and one year at the Nanyang Technological University in Singapore. A Master’s degree in v...
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    11. Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

      Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm
      Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC ...
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    12. Quantitative reconstructions in multi-modal photoacoustic and optical coherence tomography imaging

      Quantitative reconstructions in multi-modal photoacoustic and optical coherence tomography imaging
      In this paper we perform quantitative reconstruction of the electric susceptibility and the Grneisen parameter of a non-magnetic linear dielectric medium using measurement of a multi-modal photoacoustic and optical coherence tomography system. We consider the mathematical model presented in Elbauet al(2015Handbook of Mathematical Methods in Imaginged O Scherzer (New York: Springer) pp 1169204), where a Fredholm integral equation of the first kind for the Grneisen parameter was derived. For ...
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    13. Quantitative reconstructions in multi-modal photoacoustic and optical coherence tomography imaging

      Quantitative reconstructions in multi-modal photoacoustic and optical coherence tomography imaging
      In this paper we perform quantitative reconstruction of the electric susceptibility and the Gruneisen parameter of a non-magnetic linear dielectric medium using measurement of a multi-modal photoacoustic and optical coherence tomography system. We consider the mathematical model presented in [11], where a Fredholm integral equation of the first kind for the Gruneisen parameter was derived. For the numerical solution of the integral equation we consider a Galerkin type method.
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    14. The inverse scattering problem for orthotropic media in Polarization-sensitive Optical Coherence Tomography

      The inverse scattering problem for orthotropic media in Polarization-sensitive Optical Coherence Tomography
      In this paper we provide a mathematical model for imaging an anisotropic, orthotropic medium with Polarization-Sensitive Optical Coherence Tomography (PS-OCT). The imaging problem is formulated as an inverse scattering problem in three dimensions for reconstructing the electrical susceptibility of the medium using Maxwells equations. Our reconstruction method is based on the second-order Born-approximation of the electric field.
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    15. Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography

      Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography
      Purpose: To compare the diagnostic capability of 3-dimensional (3D) neuroretinal rim parameters with existing 2-dimensional (2D) neuroretinal and retinal nerve fiber layer (RNFL) thickness rim parameters using spectral domain optical coherence tomography (SD-OCT) volume scans. Materials and Methods: Design: Institutional prospective pilot study. Study population: 65 subjects (35 open-angle glaucoma patients, 30 normal patients). Observation procedures: One eye of each subject was included. SD-OCT was used to obtain 2D RNFL ...
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  2. About University of Vienna

    University of Vienna

    University of Vienna was founded in 1365 and is the oldest university in the German-speaking world and one of the largest in Central Europe. At present, about 72,000 students are enrolled at the University of Vienna, in more than 170 courses. The University of Vienna is also the largest teaching and research institution in Austria with close to 8,300 employees, 6,200 of which are scientists and academics.