1. University of Sydney

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    1. Mentioned In 47 Articles

    2. The investigation of acute optic neuritis: a review and proposed protocol

      The investigation of acute optic neuritis: a review and proposed protocol

      Optic neuritis is an inflammatory optic neuropathy that affects many patients with multiple sclerosis (MS) at some point during their disease course. Differentiation of acute episodes of MS-associated optic neuritis from other autoimmune and inflammatory optic neuropathies is vital for treatment choice and further patient management, but is not always straightforward. Over the past decade, a number of new imaging, laboratory and electrophysiological techniques have entered the clinical arena. To date, however, no consensus guidelines have been devised to specify how and when these techniques can be most rationally applied for the diagnostic work-up of patients with acute optic neuritis ...

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    3. Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). Measurement artefacts may limit the use of OCT to MS research. Objective: An expert task force convened with the aim to provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. Methods: A prospective multi-centre ( n = 13) study. Peripapillary ring scan QC rating of an OCT training set ( n = 50) was followed by a test set ( n = 50). Inter-rater agreement was calculated using kappa statistics. Results were ...

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    4. Symmetry of Retinal Parameters Measured by Spectral-domain OCT in Normal Young Adults

      Symmetry of Retinal Parameters Measured by Spectral-domain OCT in Normal Young Adults

      Purpose: To determine interocular differences in retinal parameters in a population of young adults using spectral-domain optical coherence tomography. Methods: In the Sydney Adolescent Vascular Eye Study, young adults aged 16 to 19 years received a standardized eye examination encompassing retinal photography, spectral-domain optical coherence tomography (Cirrus HD-OCT; Carl Zeiss Meditec, Dublin, CA) and best-corrected visual acuity. Interocular differences in retinal nerve fiber layer (RNFL) and macular parameters together with sex and ethnic variations for these differences were determined. Results: In the 1500 subjects tested, right eyes had thicker average RNFL than left eyes (0.3 [mu]m, P=0 ...

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    5. Relationship between macular ganglion cell complex thickness and macular outer retinal thickness: A spectral domain-optical coherence tomography study

      Relationship between macular ganglion cell complex thickness and macular outer retinal thickness: A spectral domain-optical coherence tomography study
      ... ^3 Glaucoma Unit, Sydney Eye Hospital, Sydney, New South Wales, Australia 4. ^4 Discipline of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia ^* Correspondence: Yoshiyuki Kita, MD, PhD, Departmen...
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    6. Correlation of central corneal thickness measurements using Topcon TRK-1P, Zeiss Visante AS-OCT and DGH Pachmate 55 handheld ultrasonic pachymeter

      Correlation of central corneal thickness measurements using Topcon TRK-1P, Zeiss Visante AS-OCT and DGH Pachmate 55 handheld ultrasonic pachymeter
      ...Institute Chatswood, Sydney, NSW, Australia 3. ^3 Sydney Medical School Foundation, Save Sight Institute, The University of Sydney, Sydney, NSW, Australia Email: Matthew Wells MBBS BOptom (matthew.wells@ymail.com) Public...
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    7. Retinal nerve fiber layer and optic disc measurements by spectral domain OCT: normative values and associations in young adults

      Retinal nerve fiber layer and optic disc measurements by spectral domain OCT: normative values and associations in young adults

      Purpose To determine normative values and associations of retinal nerve fiber layer (RNFL) and optic disc parameters in normal eyes measured by spectral domain optical coherence tomography (OCT). Methods In a population-based setting, 1521 young adults were examined as part of the Sydney Adolescent Vascular and Eye Study (SAVES). Their mean age was 17.3±0.6 years. RNFL and optic disc parameter measurements were made using Cirrus HD-OCT 4000. Results The average RNFL was found to be 99.4±9.6   μ m. RNFL thickness was least for the temporal quadrant (69.9±11.2   μ m), followed by the nasal ...

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    8. Optical Coherence Tomography—Guided Left Main Stem Stenting

      Optical Coherence Tomography—Guided Left Main Stem Stenting

      An 83-year-old man was referred for left main coronary artery (LMCA) stenting (Fig. 1A). After predilation, a 3.5 × 16-mm Promus™ drug-eluting stent (Boston Scientific Corporation; Natick, Mass) was deployed across the distal LMCA at a pressure of 16 atm (estimated diameter, 3.8 mm) (Fig. 1B). Optical coherence tomography (OCT) was performed after stent deployment (Fig. 1C). This measured the mean vessel diameter at 3.8 mm (area, 11.8 mm2) but, importantly, showed clear proximal malapposition of stent struts in the distal LMCA of up to 290 pm (Fig. 1C). Further balloon inflation of a 4 × 9-mm NC ...

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  2. About University of Sydney

    University of Sydney

    University of Sydney was established in Sydney in 1850 and is the oldest university in Australia. It is a member of Australia's "Group of Eight" Australian universities that are highly ranked in terms of their research performance. In 2007, the University had 45,182 students and 3,018 academic staff making it the second largest in Australia. By financial endowment it is one of the wealthiest universities in Australia.