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2. Spectral Domain Optical Coherence Tomography Features For Accurate Diagnosis
  
  Explore LWW Online Oct 24 2019 Ophthalmology
  
  UY SDC Abstract In Brief Author Information Article Metrics Purpose: To report a cohort with optic disk pit maculopathy (ODPM) presenting with neurosensory macular detachment that were initially misdiagnosed and mistreated; and to describe structural features on spectral domain optical coherence tomography in misdiagnosed and all other consecutive cases of ODPM. Methods: Multicenter international retrospective cohort study. Participants: 59 eyes from 59 patients with ODPM. Main outcome measures: 1) Proportion ...
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  Mentions: University of Sydney University of Leipzig Jasne Blonia Eye Clinic
3. Optical coherence tomography diagnostic signs in posterior uveitis
  
  Explore ScienceDirect Sep 14 2019 Ophthalmology
  
  A diagnostic sign refers to a quantifiable biological parameter that is measured and evaluated as an indicator of normal biological, pathogenic, or pharmacologic responses to a therapeutic intervention. When used in translational research discussions, the term itself often alludes to a signs used to accelerate or aid in diagnosis or monitoring and provide insight into personalized medicine. Many new diagnostic signs are being developed that involve imaging technology. Optical coherence ...
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  Mentions: Case Western Reserve University Northwestern University University of Sydney
4. Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma
  
  Explore Wiley Online Library Jul 16 2019 Ophthalmology
  
  Objective To evaluate the retina and optic nerve head (ONH) in canine eyes predisposed to glaucoma using optical coherence tomography (OCT). Animals Twenty‐five eyes (24 dogs). Methods Measures of peripapillary retinal, retinal nerve fiber layer (RNFL), and ganglion cell complex (GCC) thickness and ONH parameters were obtained in vivo by OCT of the unaffected eye in dogs diagnosed with unilateral primary glaucoma (predisposed; n = 12) and compared with measures ...
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  Mentions: University of Sydney
5. Analysis of Retinal Perfusion in Children, Adolescents, and Young Adults with Type 1 Diabetes Using Optical Coherence Tomography Angiography
  
  Explore Hindawi Publishing Corporation May 14 2019 Ophthalmology
  
  We performed a cross-sectional study to analyze the retinal vasculature in children, adolescent, and young adults with type 1 diabetes using optical coherence tomography angiography (OCTA). Patients underwent funduscopic examination for diabetic retinopathy (DR) screening during an annual visit for the screening of diabetes-related complications which included the evaluation of glycated hemoglobin (HbA1c), microalbuminuria, lipid profile, arterial pressure, and neurological assessment. In addition, OCTA of the retinal vasculature was performed ...
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  Mentions: University of Sydney University of Milan
6. Filigree vascular pattern in Combined Hamartoma of Retina and Retinal Pigment Epithelium on Optical Coherence Tomography Angiography
  
  Explore ScienceDirect May 5 2019 Ophthalmology
  
  Objective To evaluate the vascular structure within combined hamartoma of retina and retinal pigment epithelium (CHRRPE) lesions using optical coherence tomography angiography (OCT-A). Design: Multicentre retrospective observational analysis Subjects: 20 eyes of patients diagnosed with CHRRPE Methods Retrospective analysis of color fundus photographs, optical coherence tomography (OCT) and OCT-A of 20 eyes with CHRRPE. Morphological characteristics of CHRRPE and the OCT features were correlated with the density of the filigree ...
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  Mentions: L V Prasad Eye Institute LuEsther T. Mertz Retinal Research Center University of Sydney
7. Simultaneous multi-spatial scanning optical coherence tomography (OCT) based on spectrum-slicing of a broadband source
  
  Explore IOPscience Mar 14 2019
  
  This paper reports on the characterization of a novel multi-channel Optical Coherence Tomography (MC-OCT) method capable of concurrent scanning at multiple sites along the sample arm length of a low coherence interferometer. For this study, a cascade of two wavelength-based beam splitters is used to split the sample arm beam into three channels, forming three imaging (sensing) units. Channel-specific free-space beam paths are introduced in the sample arm to ensure ...
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  Mentions: University of Sydney
8. Robust deep learning method for choroidal vessel segmentation on swept source optical coherence tomography images
  
  Explore OSA | OSA Publishing Mar 5 2019 Ophthalmology
  
  Accurate choroidal vessel segmentation with swept-source optical coherence tomography (SS-OCT) images provide unprecedented quantitative analysis towards the understanding of choroid-related diseases. Motivated by the leading segmentation performance in medical images from the use of deep learning methods, in this study, we proposed the adoption of a deep learning method, RefineNet, to segment the choroidal vessels from SS-OCT images. We quantitatively evaluated the RefineNet on 40 SS-OCT images consisting of ~3 ...
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  Mentions: University of Sydney Shanghai Jiao Tong University
9. Covering our tracks – optical coherence tomography to assess vascular healing
  
  Explore eurointervention.org Dec 20 2018 Cardiology
  
  Over the better part of two decades, lessons learned from stent failure have led to technical advances that have resulted in current-generation metallic drug-eluting stents (DES) with very low rates of target lesion failure (TLF) and stent thrombosis 1 . Continued efforts have been directed at achieving iterative improvements in the design of DES to enhance adaptive vascular healing following vascular injury. By promoting early strut coverage with minimal neointimal hyperplasia ...
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  Mentions: Columbia University University of Sydney
10. Posterior Choroidal Stroma Reduces Accuracy of Automated Segmentation of Outer Choroidal Boundary in Swept Source Optical Coherence Tomography
  
  Explore IOVS Journal Sep 8 2018 Ophthalmology
  
  Purpose : To determine the influence of choroidal boundary morphology on the accuracy of automated measurements of subfoveal choroidal thickness (SFCT) in swept source optical coherence tomography (SSOCT). Methods : A retrospective image analysis of foveal-centered horizontal line scans from normal and diseased eyes using the Topcon DRI OCT-1 Atlantis SSOCT was conducted. Subfoveal choroid-scleral junction (CSJ) and retina-choroidal junction (RCJ) morphologies were graded by two observers. Automated SFCT (A-SFCT) was compared ...
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  Mentions: Topcon Medical Systems University of Western Australia University of Sydney
11. DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images
  
  Explore OSA | OSA Publishing Jul 1 2018 Ophthalmology
  
  Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm (custom U-NET) was designed and trained to segment 6 ONH tissue layers by capturing both the local (tissue texture ...
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  Mentions: University College London Singapore Eye Research Institute National University of Singapore
12. DRUNET: A Dilated-Residual U-Net Deep Learning Network to Digitally Stain Optic Nerve Head Tissues in Optical Coherence Tomography Images
  
  Explore arxiv.org Mar 8 2018 Ophthalmology
  
  Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm was designed and trained to digitally stain (i.e. highlight) 6 ONH tissue layers by capturing both the local ...
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  Mentions: University College London Singapore Eye Research Institute National University of Singapore
13. Comparing optical coherence tomography findings in different aetiologies of infectious necrotising retinitis
  
  Explore BJO Online Aug 7 2017 Ophthalmology
  
  Abstract Aims To compare optical coherence tomography (OCT) features of active necrotising infectious retinitis (NIR) due to toxoplasmosis or herpesviruses and to determine distinctive OCT signs for these two causes of infectious retinitis. Methods OCT scans from eyes with active NIR due to varicella zoster virus (VZV), herpes simplex virus (HSV), cytomegalovirus (CMV), and toxoplasmosis (TOXO) were reviewed. All images were evaluated for the presence of previously described OCT findings ...
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  Mentions: University of Sydney University of Milan Giovanni Staurenghi
14. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
  
  Explore ScienceDirect May 29 2017 Cardiology
  
  Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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  Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto
15. Feature Of The Week 05/28/2017: In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements
  
  Explore Optical Coherence Tomography News May 28 2017 Ophthalmology
  
  Glaucoma is characterized by an irreversible damage of retinal ganglion cells within the optic nerve head (ONH) at the back of the eye. Currently we know that elevated intraocular pressure (IOP) is associated with increased prevalence of glaucoma but not all glaucoma patients have an elevated IOP. The biomechanical theory of glaucoma hypothesizes that elevated (or fluctuating) IOP deforms the ONH tissues, including the lamina cribrosa (LC), and that these ...
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  Mentions: Duke University University College London National University of Singapore
16. Accuracy of optical coherence tomography for the diagnosis of superficial basal cell carcinoma – a prospective, consecutive, cohort study of 168 cases
  
  Explore Wiley Online Library May 5 2016 Dermatology , Oncology
  
  ...he most expensive cancers to treat.(4) Melanoma Institute Australia, North Sydney, New South Wales, Australia University of Sydney, Sydney Medical School, Sydney, New South Wales, Australia Royal Prince Alfred Hospital, ...
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  Mentions: University of Sydney
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