1. University of St. Andrews

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    1. Mentioned In 30 Articles

    2. Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study

      Diagnostic accuracy of optical coherence tomography for diagnosing glaucoma: secondary analyses of the GATE study
      Background/Aims To assess the diagnostic performance of retinal nerve fibre layer (RNFL) data of optical coherence tomography (OCT) for detecting glaucoma. Methods Secondary analyses of a prospective, multicentre diagnostic study (Glaucoma Automated Tests Evaluation (GATE)) referred to hospital eye services in the UK were conducted. We included data from 899 of 966 participants referred to hospital eye services with suspected glaucoma or ocular hypertension. We used both eyes data ...
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    3. Feature Of The Week 08/06/2017: Depth-resolved multimodal imaging: Wavelength modulated spatially offset Raman spectroscopy with OCT

      Feature Of The Week 08/06/2017: Depth-resolved multimodal imaging: Wavelength modulated spatially offset Raman spectroscopy with OCT
      ...s for neuroscience. For more information see recent Article . Courtesy Mingzhou Chen and Kishan Dholakia from University of St. Andrews . There is now a major drive to obtain complementary information using photonics app...
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    4. Depth-resolved multimodal imaging: Wavelength Modulated Spatially Offset Raman Spectroscopy with Optical Coherence Tomography

      Depth-resolved multimodal imaging: Wavelength Modulated Spatially Offset Raman Spectroscopy with Optical Coherence Tomography
      A major challenge in biophotonics is multimodal imaging to obtain both morphological and molecular information at depth. We demonstrate a hybrid approach integrating optical coherence tomography (OCT) with wavelength modulated spatially offset Raman spectroscopy (WM-SORS). With depth co-localization obtained from the OCT, we can penetrate 1.2mm deep into the strong scattering media (lard) to acquire up to a 14-fold enhancement of a Raman signal from a hidden target (Polystyrene ...
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    5. Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study

      Automated imaging technologies for the diagnosis of glaucoma: a comparative diagnostic study for the evaluation of the diagnostic accuracy, performance as triage tests and cost-effectiveness (GATE study
      Background Many glaucoma referrals from the community to hospital eye services are unnecessary. Imaging technologies can potentially be useful to triage this population. Objectives To assess the diagnostic performance and cost-effectiveness of imaging technologies as triage tests for identifying people with glaucoma. Design Within-patient comparative diagnostic accuracy study. Markov economic model comparing the cost-effectiveness of a triage test with usual care. Setting Secondary care. Participants Adults referred from the community ...
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    6. Internal physiology of live krill revealed using new aquaria techniques and mixed optical microscopy and optical coherence tomography (OCT) imaging techniques

      Internal physiology of live krill revealed using new aquaria techniques and mixed optical microscopy and optical coherence tomography (OCT) imaging techniques
      The accurate observation of physiological changes on in vivo samples of important animal species such as Euphausia superba (Antarctic krill) is an important goal in helping to understand how environmental changes can affect animal development. Using a custom made krill trap, live un-anaesthetized krill were confined for seven hours, during which three hours of optical imaging were obtained and no subsequent ill effects observed. The trap enabled two imaging methods ...
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    7. Optical coherence tomography for the diagnosis, monitoring and guiding of treatment for neovascular age-related macular degeneration: a systematic review and economic evaluation

      Optical coherence tomography for the diagnosis, monitoring and guiding of treatment for neovascular age-related macular degeneration: a systematic review and economic evaluation
      Background Age-related macular degeneration is the most common cause of sight impairment in the UK. In neovascular age-related macular degeneration (nAMD), vision worsens rapidly (over weeks) due to abnormal blood vessels developing that leak fluid and blood at the macula. Objectives To determine the optimal role of optical coherence tomography (OCT) in diagnosing people newly presenting with suspected nAMD and monitoring those previously diagnosed with the disease. Data sources Databases ...
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    8. The Application of Optical Coherence Tomography to Image Subsurface Tissue Structure of Antarctic Krill Euphausia superba

      The Application of Optical Coherence Tomography to Image Subsurface Tissue Structure of Antarctic Krill Euphausia superba
      ...h, St Andrews, Fife, United Kingdom X * Praveen C. Ashok, Affiliation: SUPA, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife, United Kingdom X * Kishan Dholakia, Affiliation: SUPA...
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    9. Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review

      Optical coherence tomography for the diagnosis of neovascular age-related macular degeneration: a systematic review
      The purpose is to study the diagnostic performance of optical coherence tomography (OCT) and alternative diagnostic tests for neovascular age-related macular degeneration (nAMD). Methods employed are as follows:systematic review and meta-analysis; Index test: OCT including time-domain (TD-OCT) and the most recently developed spectral domain (SD-OCT); comparator tests: visual acuity, clinical evaluation (slit lamp), Amsler chart, colour fundus photographs, infra-red reflectance, red-free images / blue reflectance, fundus autofluorescence imaging (FAF), indocyanine ...
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    10. Bessel beams from semiconductor light sources

      Bessel beams from semiconductor light sources
      We report on recent progress in the generation of non-diffracting (Bessel) beams from semiconductor light sources including both edge-emitting and surface-emitting semiconductor lasers as well as light-emitting diodes (LEDs). Bessel beams at the power level of Watts with central lobe diameters of a few to tens of micrometers were achieved from compact and highly efficient lasers. The practicality of reducing the central lobe size of the Bessel beam generated with ...
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    11. Light sheet imaging the Airy way

      Light sheet imaging the Airy way
      Recent decades have seen an expansion in the breadth of light-based imaging techniques that address problems in biomedicine. Despite perceived limitations in terms of penetration depth and resolution, optical imaging has made significant strides to encroach upon the traditional territory of other modalities, such as electron microscopy and x-ray. At the nanoscale, optical methods exploit light fields in tandem with the properties of fluorescent proteins to answer biological questions in ...
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    12. Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination

      Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination
      Optical spectroscopy and imaging methods have proved to have potential to discriminate between normal and abnormal tissue types through minimally invasive procedures. Raman spectroscopy and Optical Coherence Tomography (OCT) provides chemical and morphological information of tissues respectively, which are complementary to each other. When used individually they might not be able to obtain high enough sensitivity and specificity that is clinically relevant. In this study we combined Raman spectroscopy information ...
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    13. 1-15 of 30 1 2 »
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  2. About University of St. Andrews

    University of St. Andrews

    University of St. Andrews is the oldest university in Scotland and third oldest in the English-speaking world, having been founded between 1410 and 1413. The University is situated in the town of St Andrews, in Fife, on the east coast of Scotland. It is a member of the 1994 Group, a network of smaller research-intensive British universities. Intake is highly selective and Independent school intake is high. University of St Andrews Biophotonics & OCT Research.