1. University of Southern California

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    1. Mentioned In 272 Articles

    2. The cellular origins of the outer retinal bands in optical coherence tomography images

      The cellular origins of the outer retinal bands in optical coherence tomography images

      Purpose: To test the recently proposed hypothesis that the second OCT outer retinal band originates from the inner segment ellipsoid, by measuring: 1) thickness of this band within single cones, and 2) its respective distance from the external limiting membrane and outer segment tips. Methods: Adaptive optics OCT images were obtained from four normal subjects. Images were obtained at foveal (2∘) and perifoveal (5∘) locations. Cones (n = 9593) were identified and segmented in three dimensions using custom software. Features corresponding to bands 1, 2, and 3 were automatically identified. Thickness of band 2 was assessed in each cell by fitting ...

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    3. Macular Thickness Measurements in Normal Eyes Using Spectral Domain Optical Coherence Tomography

      Macular Thickness Measurements in Normal Eyes Using Spectral Domain Optical Coherence Tomography

      BACKGROUND AND OBJECTIVE: Knowledge of the macular thickness in a normal population is important for the evaluation of pathological macular change. The purpose of this study was to define and measure macular thickness in normal eyes using spectral domain optical coherence tomography (OCT). PATIENTS AND METHODS: Fifty eyes from 50 normal subjects (29 men and 21 women, aged 22 to 68 years) were scanned with a prototype Cirrus HD-OCT system (5 µm axial resolution) (Carl Zeiss Meditec, Inc.). The proprietary Cirrus segmentation algorithm was used to produce retinal thickness maps, which were then averaged over 9 regions defined by a ...

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    4. OCT in the Management of Macular Degeneration - Ophthalmology Education Lab

      OCT in the Management of Macular Degeneration - Ophthalmology Education Lab

      Advances in retinal pharmacology have significantly improved outcomes for patients with a range of chronic retinal conditions, including age-related macular degeneration, macular edema, retinal vascular disorders and diseases of the vitreomacular interface. Maximizing the efficacy of available treatments requires the appropriate use of optical coherence tomography (OCT) to diagnose these conditions and to monitor the efficacy of treatment. In this webinar series, leading clinicians and researchers will discuss the role of OCT in detecting structural changes associated with a range of retinal diseases and provide clinical pearls on using tools such as thickness maps, automated change analysis and angiography in ...

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    5. Grader learning effect and reproducibility of Doppler Spectral‐Domain Optical Coherence Tomography derived retinal blood flow measurements

      Grader learning effect and reproducibility of Doppler Spectral‐Domain Optical Coherence Tomography derived retinal blood flow measurements
      ...& Science University, Portland, Oregon, USA 5. ^5 Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA ^* Correspondence Professor Christopher Huds...
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    6. Reproducibility of Angle Metrics Using the Time-Domain Anterior Segment Optical Coherence Tomography: Intra-Observer and Inter-Observer Variability

      Reproducibility of Angle Metrics Using the Time-Domain Anterior Segment Optical Coherence Tomography: Intra-Observer and Inter-Observer Variability

      Purpose : To evaluate the reproducibility of anterior chamber angle measurements obtained by the Zeiss Visante anterior segment optical coherence tomography (AS-OCT). Methods : Twenty eyes from 20 normal subjects with open anterior chamber angles were studied. The anterior chamber angle was imaged using the Visante AS-OCT. The angle-opening distance (AOD 500, AOD 750), trabercular iris space area (TISA 500, TISA 750) and scleral spur angle (SS angle) at the inferior angle location were measured. All the subjects underwent imaging in a darkened room (1 foot candles measured at the eye). Images were graded in a masked fashion by certified Doheny Image ...

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    7. Robot-assisted three-dimensional registration for cochlear implant surgery using a common-path swept-source optical coherence tomography probe

      Robot-assisted three-dimensional registration for cochlear implant surgery using a common-path swept-source optical coherence tomography probe

      Cochlear implantation offers the potential to restore sensitive hearing in patients with severe to profound deafness. However, surgical placement of the electrode array within the cochlea can produce trauma to sensorineural components, particularly if the initial turn of the cochlea is not successfully navigated as the array is advanced. In this work, we present a robot-mounted common-path swept-source optical coherence tomography endoscopic platform for three-dimensional (3-D) optical coherence tomography (OCT) registration and preoperative surgical planning for cochlear implant surgery. The platform is composed of a common-path 600- μ m diameter fiber optic rotary probe attached to a five degrees of freedom ...

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    8. Proposed Lexicon for Anatomic Landmarks in Normal Posterior Segment Spectral-Domain Optical Coherence Tomography: The IN•OCT Consensus

      Proposed Lexicon for Anatomic Landmarks in Normal Posterior Segment Spectral-Domain Optical Coherence Tomography: The IN•OCT Consensus
      ...ail address , * Srinivas Sadda, MD Affiliations + Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California , * Usha Chakravarthy, FRCOphth, PhD Affiliations +...
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    9. Frequency of abnormal retinal nerve fibre layer and ganglion cell layer SDOCT scans in healthy eyes and glaucoma suspects in a prospective longitudinal study

      Frequency of abnormal retinal nerve fibre layer and ganglion cell layer SDOCT scans in healthy eyes and glaucoma suspects in a prospective longitudinal study
      ...urgh, Pennsylvania, USA 4. ^4Department of Ophthalmology, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA 1. Correspondence to Dr David S Greenfield, ...
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    10. Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis

      Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis

      Accurate assessment of atherosclerotic plaque characteristics and the subsequent tailoring of optimal therapy holds great promise for preventing acute coronary syndromes (ACS) and life-threatening sequelae 1 . Combined use of optical coherence tomography (OCT) and intravascular ultrasound (IVUS) was proposed as a potential method for accurate assessment of plaque characteristics and vulnerability ( 2 , ). However, significant challenges remain in trying to adapt an integrated OCT-IVUS system for clinical applications. We report here a fully integrated intracoronary OCT-IVUS imaging technique to visualize atherosclerotic plaque in living animals and human coronary arteries from cadavers with high resolution and deep penetration capability simultaneously.

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    11. 1-15 of 272 1 2 3 4 ... 16 17 18 »
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  2. About University of Southern California

    University of Southern California

    University of Southern California is located in Los Angeles, a global center for arts, technology and international trade and is one of the world’s leading private research universities. USC enrolls more international students than any other U.S. university and offers extensive opportunities for internships and study abroad. With a strong tradition of integrating liberal and professional education, USC fosters a vibrant culture of public service and encourages students to cross academic as well as geographic boundaries in their pursuit of knowledge. The Keck School of Medicine is the medical school at the University of Southern California. Founded in 1885 as the USC College of Medicine, it was closed in 1921 and reopened in 1928 as the USC School of Medicine.