1. University of Southern California

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    1. Mentioned In 320 Articles

    2. Miniature probe for mapping mechanical properties of vascular lesions using acoustic radiation force optical coherence elastography

      Miniature probe for mapping mechanical properties of vascular lesions using acoustic radiation force optical coherence elastography
      Cardiovascular diseases are the leading cause of fatalities in the United States. Atherosclerotic plaques are one of the primary complications that can lead to strokes and heart attacks if left untreated. It is essential to diagnose the disease early and distinguish vulnerable plaques from harmless ones. Many methods focus on the structural or molecular properties of plaques. Mechanical properties have been shown to change drastically when abnormalities develop in arterial ...
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    3. Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis

      Methods and systems to measure corneal epithelial thickness and power, stromal thickness, subepithelial corneal power and topography for disease diagnosis
      This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as ...
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    4. USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans

      USC ReceivesNIH Grant for Defining the Relationship of Retinal MIcrocirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African Americans
      ...fessor of Ophthalmology in the Glaucoma Division at the USC Roski Eye Institute at Keck School of Medicine of University of Southern California. The primary objectives of this K23 career development proposal are: 1) to p...
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    5. USC Roski Eye Institute experts present novel research in preventive care, diagnosis and treatment of visual impairment and eye diseases at ARVO Annual Meeting

      USC Roski Eye Institute experts present novel research in preventive care, diagnosis and treatment of visual impairment and eye diseases at ARVO Annual Meeting
      ...ovative treatments that preserve, and in some cases, restore vision," said Rohit Varma , MD, MPH, dean of the Keck School of Medicine of USC and director of the USC Roski Eye Institute. "Whether it is multi-ethnic popula...
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    6. 3D in vivo imaging with extended-focus optical coherence microscopy

      3D in vivo imaging with extended-focus optical coherence microscopy
      Optical coherence microscopy (OCM) has unique advantages of non-invasive 3D imaging without the need of exogenous labels for studying biological samples. However, the imaging depth of this technique is limited by the tradeoff between the depth of focus (DOF) and high lateral resolution in Gaussian optics. To overcome this limitation, we have developed an extended-focus OCM (xf-OCM) imaging system using quasi-Bessel beam illumination to extend the DOF to 100 m ...
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    7. Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography

      Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography
      ...ging device. Research was conducted in compliance with the Declaration of Helsinki and with approval from the University of Southern California (USC) Institutional Review Board. As part of their routine clinical care, al...
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    8. Optical coherence microscopy with extended focus for in vivo embryonic imaging

      Optical coherence microscopy with extended focus for in vivo embryonic imaging
      Optical coherence microscopy (OCM) has unique advantages of high-resolution volumetric imaging without relying on exogenous labels or dyes. It combines the coherence-gated depth discrimination of optical coherence tomography (OCT) with the high lateral resolution of confocal microscopy, offering an excellent balance between the resolutions and imaging depth. However, as the lateral resolution becomes higher, the imaging depth of OCM decreases and its three-dimensional imaging capability is greatly degraded. To overcome ...
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    9. Phase variance optical coherence microscopy for label-free imaging of the developing vasculature in zebrafish embryos

      Phase variance optical coherence microscopy for label-free imaging of the developing vasculature in zebrafish embryos
      A phase variance optical coherence microscope (pvOCM) has been created to image blood flow in the microvasculature of zebrafish embryos, without the use of exogenous labels. The pvOCM imaging system has axial and lateral resolutions of 2.8 m 2.8m in tissue and imaging depth of more than 100 m 100m . Images of 2 to 5 days postfertilization zebrafish embryos identified the detailed anatomical structure based on OCM intensity ...
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    10. USC Roski Eye Institute Joins the ARVO Campaign to Promote the Impact of Optical Coherence Tomography, USC Clinician/Scientist one of OCT Inventors

      USC Roski Eye Institute Joins the ARVO Campaign to Promote the Impact of Optical Coherence Tomography, USC Clinician/Scientist one of OCT Inventors
      ... 25 years of the revolutionary impact of optical coherence tomography (OCT) on eye care around the world, the University of Southern California (USC) Roski Eye Institute, which helped pioneer OCT, has partnered with the ...
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    11. The Future of Optical Coherence Tomography | USC Roski Eye Institute

      The Future of Optical Coherence Tomography | USC Roski Eye Institute
      Over the past few decades many technologies have revolutionized the practice of medicine. Perhaps one of the most revolutionary technologies has been Optical Coherence Tomography (OCT). Since the first high profile description of OCT technology in 1991 in the journal Science, this technology has dramatically transformed the way physicians diagnose and treat their patients in several fields in medicine. For Ophthalmology, OCT imaging has become a noninvasive diagnostic tool that ...
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    12. Widefield OCT Findings of a Patient With Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis

      Widefield OCT Findings of a Patient With Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis
      The authors report extensive peripheral retinoschisis in a patient with stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) detected by widefield optical coherence tomography (OCT). A 64-year-old woman diagnosed with foveomacular retinoschisis 3 years prior presented for evaluation after being seen by multiple other retina specialists. Standard macular spectral-domain OCT (6 mm) revealed typical foveomacular schisis involving only the outer retina. However, widefield OCT (12 mm) revealed diffuse bilateral retinoschisis involving both ...
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    13. Quantifying Microvascular Density and Morphology in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography Angiography

      Quantifying Microvascular Density and Morphology in Diabetic Retinopathy Using Spectral-Domain Optical Coherence Tomography Angiography
      Purpose : To quantify changes in retinal microvasculature in diabetic retinopathy (DR) by using spectral-domain optical coherence tomography angiography (SD-OCTA). Methods : Retrospective, cross-sectional, observational study of healthy and diabetic adult subjects with and without DR. Retinal microvascular changes were assessed by using SD-OCTA images and an intensity-based optical microangiography algorithm. A semiautomated program was used to calculate indices of microvascular density and morphology in nonsegmented and segmented SD-OCTA images. Microvascular density ...
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  2. About University of Southern California

    University of Southern California

    University of Southern California is located in Los Angeles, a global center for arts, technology and international trade and is one of the world’s leading private research universities. USC enrolls more international students than any other U.S. university and offers extensive opportunities for internships and study abroad. With a strong tradition of integrating liberal and professional education, USC fosters a vibrant culture of public service and encourages students to cross academic as well as geographic boundaries in their pursuit of knowledge. The Keck School of Medicine is the medical school at the University of Southern California. Founded in 1885 as the USC College of Medicine, it was closed in 1921 and reopened in 1928 as the USC School of Medicine.