1. University of Sheffield

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    1. Mentioned In 112 Articles

    3. Imaging striae distensae: a comparison between PS-OCT and digital dermoscopy

      Explore OSA | OSA Publishing Dermatology
      Imaging striae distensae: a comparison between PS-OCT and digital dermoscopy
      Stretch marks or striae distensae (SD) cause emotional distress and negatively affect the psychological well-being of patients. We investigate and compare two methods for quantifying the severity of SD: visual scoring of images captured using a clinical visible-light dermatological camera (C-Cube, Pixience Inc) and measuring the local birefringence of skin using polarization-sensitive optical coherence tomography (PS-OCT). Data on skin visually affected by SD and visually normal skin were collected from ...
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      Mentions: University of Sheffield

    5. Bandwidth enhancement in an InGaN/GaN three-section superluminescent diode for optical coherence tomography

      Explore aip.scitation.org Broadband Sources
      Bandwidth enhancement in an InGaN/GaN three-section superluminescent diode for optical coherence tomography
      In this paper, the optoelectronic properties of InGaN-based blue (430nm) superluminescent light-emitting diodes with a multi-section, three contact design are reported. The bias conditions of the rear absorber section and gain sections are explored in terms of enhancing and maximizing spectral bandwidth. We demonstrate that broader emission can be obtained with a short circuit, rather than an open circuit absorber section, and with two active regions at different current densities ...
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      Mentions: University of Sheffield Wakayama Medical University Kobe University Graduate School of Medicine

    8. Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography

      Explore ScienceDirect Dermatology
      Morphological parametric mapping of 21 skin sites throughout the body using optical coherence tomography
      Background Changes in body posture cause changes in morphological properties at different skin sites. Although previous studies have reported the thickness of the skin, the details of the postures are not generally given. This paper presents the effect of a change in posture on parameters such as thickness and surface roughness in 21 load-bearing and non-load-bearing sites. Materials and methods A total of 12 volunteers (8 males and 4 females ...
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      Mentions: Michelson Diagnostics University of Sheffield

    9. Attenuation of stripe artifacts in optical coherence tomography images through wavelet-FFT filtering

      Explore OSA | OSA Publishing
      Attenuation of stripe artifacts in optical coherence tomography images through wavelet-FFT filtering
      The use of polarization-maintaining (PM) fibers for polarization-sensitive optical coherence tomography (PS-OCT) can result in numerous image artifacts which degrade the reliability of birefringence measurements. Similar artifacts can also arise in conventional OCT, due to stray reflections from optical surfaces, a problem which is increasing in tandem with the steady rise in source coherence lengths. Here, a recently presented wavelet-FFT filter[Opt. Express 17 (10), 8567 (2009). [ PubMed ] ] is combined ...
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      Mentions: University of Sheffield

    10. Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix

      Explore OSA | OSA Publishing Gynecology , Probes
      Polarization-sensitive optical coherence tomography with a conical beam scan for the investigation of birefringence and collagen alignment in the human cervix
      By measuring the phase retardance of a cervical extracellular matrix, our in-house polarization-sensitive optical coherence tomography (PS-OCT) was shown to be capable of (1) mapping the distribution of collagen fibers in the non-gravid cervix, (2) accurately determining birefringence, and (3) measuring the distinctive depolarization of the cervical tissue. A conical beam scan strategy was also employed to explore the 3D orientation of the collagen fibers in the cervix by interrogating ...
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      Mentions: University of Sheffield

    13. Superparamagnetic graphene quantum dot as a dual‐modality contrast agent for confocal fluorescence microscopy and magnetomotive optical coherence tomography

      Explore Wiley Online Library Microscopy
      Superparamagnetic graphene quantum dot as a dual‐modality contrast agent for confocal fluorescence microscopy and magnetomotive optical coherence tomography
      A magnetic graphene quantum dot (MGQD) nanoparticle, synthesized by hydrothermally reducing and cutting graphene oxide‐iron oxide sheet, was demonstrated to possess the capabilities of simultaneous confocal fluorescence and magnetomotive optical coherence tomography (MMOCT) imaging. This MGQD shows low toxicity, significant tunable blue fluorescence and superparamagnetism, which can thus be used as a dual‐modality contrast agent for confocal fluorescence microscopy (CFM) and MMOCT. The feasibility of applying MGQD as ...
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      Mentions: University of Sheffield

    14. Near-infrared and mid-infrared semiconductor broadband light emitters

      Explore Nature Publishing Group Broadband Sources
      Near-infrared and mid-infrared semiconductor broadband light emitters
      Semiconductor broadband light emitters have emerged as ideal and vital light sources for a range of biomedical sensing/imaging applications, especially for optical coherence tomography systems. Although near-infrared broadband light emitters have found increasingly wide utilization in these imaging applications, the requirement to simultaneously achieve both a high spectral bandwidth and output power is still challenging for such devices. Owing to the relatively weak amplified spontaneous emission, as a consequence ...
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      Mentions: University of Sheffield Chinese Academy of Sciences

    15. Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography

      Explore OSA | OSA Publishing Dermatology
      Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography
      Measurement of sub-clinical atopic dermatitis (AD) is important for determining how long therapies should be continued after clinical clearance of visible AD lesions. An important biomarker of subclinical AD is epidermal hypertrophy, the structural measures of which often make optical coherence tomography (OCT) challenging due to the lack of a clearly delineated dermal-epidermal junction in AD patients. Alternatively, angiographic OCT measurements of vascular depth and morphology may represent a robust ...
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      Mentions: University of Sheffield

    16. Vascular patterning of subcutaneous mouse fibrosarcomas expressing individual VEGF isoforms can be differentiated using angiographic optical coherence tomography

      Explore OSA | OSA Publishing
      Vascular patterning of subcutaneous mouse fibrosarcomas expressing individual VEGF isoforms can be differentiated using angiographic optical coherence tomography
      Subcutaneously implanted experimental tumors in mice are commonly used in cancer research. Despite their superficial location, they remain a challenge to image non-invasively at sufficient spatial resolution for microvascular studies. Here we evaluate the capabilities of optical coherence tomography (OCT) angiography for imaging such tumors directly through the murine skin in-vivo. Data sets were collected from mouse tumors derived from fibrosarcoma cells genetically engineered to express only single splice variant ...
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      Mentions: University of Sheffield
    17. 1-15 of 112 1 2 3 4 5 6 7 8 »
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  4. About University of Sheffield

    University of Sheffield

    The University of Sheffield in England is one of the UK's leading universities.   We have nearly 24,000 students from 124 countries, and almost 6000 staff.  Engineering Materials Department at The University of Sheffield, England has interest is in the development and application of novel biophotonic tools to aid the characterisation of biological tissues. Photonics offers many unique advantages over other imaging techniques for studying biological systems, including structural and functional contrast, cellular level resolution, speed, non-destructiveness and cost.

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