1. University of Rochester

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    1. Mentioned In 140 Articles

    2. Cascade Optical Coherence Tomography (C-OCT) for Surface Form Metrology of - ProQuest

      Cascade Optical Coherence Tomography (C-OCT) for Surface Form Metrology of - ProQuest
      Freeform optical components enable dramatic advances in optical system performance and packaging. As the saying goes, one cannot make what one cannot measure. Surface form metrology of as-built freeform optics remains a challenge and an active area of research. In this dissertation, a novel cascade optical coherence tomography (C-OCT) technique was conceived towards addressing this metrology challenge. The C-OCT theoretical framework was developed, and a metrology system was built to ...
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    3. Schizophrenia in Translation: Why the Eye?

      Schizophrenia in Translation: Why the Eye?
      Schizophrenia is increasingly recognized as a systemic disease, characterized by dysregulation in multiple physiological systems (eg, neural, cardiovascular, endocrine). Many of these changes are observed as early as the first psychotic episode, and in people at high risk for the disorder. Expanding the search for biomarkers of schizophrenia beyond genes, blood, and brain may allow for inexpensive, noninvasive, and objective markers of diagnosis, phenotype, treatment response, and prognosis. Several anatomic ...
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    4. Local Burr distribution estimator for speckle statistics

      Local Burr distribution estimator for speckle statistics
      Speckle statistics in ultrasound and optical coherence tomography have been studied using various distributions, including the Rayleigh, the K, and the more recently proposed Burr distribution. In this paper, we expand on the utility of the Burr distribution by first validating its theoretical framework with numerical simulations and then introducing a new local estimator to characterize sample tissues of liver, brain, and skin using optical coherence tomography. The spatially local ...
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    5. OCT and OCT Angiography Offer New Insights and Opportunities in Schizophrenia Research and Treatment

      OCT and OCT Angiography Offer New Insights and Opportunities in Schizophrenia Research and Treatment
      The human retina and retinal imaging technologies continue to increasingly gain the attention of schizophrenia researchers. With the same embryologic origin as the brain, the retina offers a window into neurovascular changes that may underlie disease. Recently, two technologies that have already revolutionized the field of ophthalmology, optical coherence tomography (OCT), and a functional extension of this, optical coherence tomography angiography (OCTA), have gained traction. Together, these non-invasive technologies allow ...
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    6. Optical coherence tomography spurs quantum leap in hearing research

      Optical coherence tomography spurs quantum leap in hearing research
      Nam is using the same tool that helped ophthalmologists achieve major advances in vision correction. Optical coherence tomography is an imaging technique that allows researchers to capture micrometer-resolution, two- and three-dimensional images from within biological tissues. The technology has provided a quantum leap forward in cochlear research, says Nam, whose lab occupies a unique niche in the field. Other research groups use the imaging technology to study the vibration of ...
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    7. Assessing corneal cross-linking with reverberant 3D optical coherence elastography

      Assessing corneal cross-linking with reverberant 3D optical coherence elastography
      Significance: Corneal cross-linking (CXL) is a well-known procedure for treating certain eye disorders such as keratoconus. However, characterization of the biomechanical changes in the cornea as a result of this procedure is still under active research. Specifically, there is a clinical need for high-resolution characterization of individual corneal layers. Aim: A high-resolution elastography method in conjunction with a custom optical coherence tomography system is used to track these biomechanical changes ...
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    8. University or Rochester Receives NIH Grant for Investigation of Brain Elasticity in Aging and Alzheimer's Disease Enabled by Optical Coherence Elastography

      University or Rochester Receives NIH Grant for Investigation of Brain Elasticity in Aging and Alzheimer's Disease Enabled by Optical Coherence Elastography
      ...t and progression of Alzheimers disease using mouse models, with direct implications to future human studies. University of Rochester Receives a 2021 NIH Grant for $51,036 for Investigation of Brain Elasticity in Aging a...
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    9. Estimation of scleral mechanical properties from air-puff optical coherence tomography

      Estimation of scleral mechanical properties from air-puff optical coherence tomography
      We introduce a method to estimate the biomechanical properties of the porcine sclera in intact eye globes ex vivo , using optical coherence tomography that is coupled with an air-puff excitation source, and inverse optimization techniques based on finite element modeling. Air-puff induced tissue deformation was determined at seven different locations on the ocular globe, and the maximum apex deformation, the deformation velocity, and the arc-length during deformation were quantified. In ...
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    10. 1st International Conference Advances in 3OM: Opto-Mechatronics, Opto-Mechanics and Optical Metrology, Timisoara, Romania, December 13, 2021

      1st International Conference Advances in 3OM: Opto-Mechatronics, Opto-Mechanics and Optical Metrology, Timisoara, Romania, December 13, 2021
      The 3OM concept reunites three complementary domains: (1) Opto-Mechatronics is a blend of Optics Photonics, Precision Mechanics, Electronics, Control Automation, as well as IT. (2) Opto-Mechanics usually fills the gap between the high requirements of Optical Design and the capabilities of Mechanical technologies, addressing tolerances, errors, positioning issues, and methods to tackle them. Kinematic and dynamic aspects of optical systems with moving parts are also approached, and this leads back ...
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    11. Verification of cascade optical coherence tomography for freeform optics form metrology

      Verification of cascade optical coherence tomography for freeform optics form metrology
      Freeform optical components enable dramatic advances for optical systems in both performance and packaging. Surface form metrology of manufactured freeform optics remains a challenge and an active area of research. Towards addressing this challenge, we previously reported on a novel architecture, cascade optical coherence tomography (C-OCT), which was validated for its ability of high-precision sag measurement at a given point. Here, we demonstrate freeform surface measurements, enabled by the development ...
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    12. Speckle Statistics of Biological Tissues in Optical Coherence Tomography

      Speckle Statistics of Biological Tissues in Optical Coherence Tomography
      The speckle statistics of optical coherence tomography images of biological tissue have been studied using several historical probability density functions. A recent hypothesis implies that underlying power-law distributions in the medium structure, such as the fractal branching vasculature, will contribute to power-law probability distributions of speckle statistics. Specifically, these are the Burr type XII distribution for speckle amplitude, the Lomax distribution for intensity, and the generalized logistic distribution for log ...
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    13. Line-field confocal optical coherence tomography for three-dimensional skin imaging

      Line-field confocal optical coherence tomography for three-dimensional skin imaging
      This paper reports on the latest advances in line-field confocal optical coherence tomography (LC-OCT), a recently invented imaging technology that now allows the generation of either horizontal ( x y ) section images at an adjustable depth or vertical ( x z ) section images at an adjustable lateral position, as well as three-dimensional images. For both two-dimensional imaging modes, images are acquired in real-time, with real-time control of the depth and lateral positions ...
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    14. 1-15 of 140 1 2 3 4 5 6 7 8 9 10 »
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  2. About University of Rochester

    University of Rochester

    University of Rochester, founded in 1850, is one of the nation's leading private universities. With just over 4,500 undergraduates, Rochester is one of the smallest and most collegiate in character among the top research universities

    Founded in 1850, UR offers degree programs at the bachelor's, master's, and doctoral levels, as well as in several professional disciplines. Its undergraduate and graduate degree programs in political science, business administration and music are among the best in the nation. The Institute of Optics at the university is also the oldest optics program in the U.S., having granted about half of the optics degrees in the nation.

    UR is a highly research oriented institution, hosting numerous centers of research, including the Laboratory for Laser Energetics, which boasts the most powerful ultraviolet laser in the world, and the University of Rochester Medical Center, featuring numerous biomedical and healthcare research facilities. Since 2005, UR with its affiliated Strong Health System, has been the largest employer in the Greater Rochester area.