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    1. Mentioned In 247 Articles

    2. Study of retinal structural–functional relationship in choroideremia using fundus autofluorescence and optical coherence tomography

      Explore Nature Publishing Group Ophthalmology
      Study of retinal structural–functional relationship in choroideremia using fundus autofluorescence and optical coherence tomography
      Objective The objective of this study was to assess the structuralfunctional relationship in choroideremia (CHM) patients using optical coherence tomography (OCT) and autofluorescence (AF) images. Methods In this study, 53 eyes of 28 CHM patients were included. Demographic, ocular and clinical fundus features were recorded. Fundus AF and OCT images were analysed. Patients were classified into two groups based on AF features: group 1, CHM patients where the foveal island ...
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      Mentions: University of Pittsburgh Rohit Shetty

    3. OCT-Angiography as a reliable prognostic tool in laser-treated proliferative diabetic retinopathy: The RENOCTA Study

      Explore SAGE Journals Ophthalmology
      OCT-Angiography as a reliable prognostic tool in laser-treated proliferative diabetic retinopathy: The RENOCTA Study
      Purpose: To quantitatively assess retinal neovascularizations (RNVs) in proliferative diabetic retinopathy (PDR) before and after photocoagulative laser treatment (PLT) using Optical Coherence Tomography Angiography (OCT-A). Methods: Consecutive patients with PDR were examined with fluorescein angiography (FA) and OCT-A before and after PLT. Baseline and after-treatment FA images were quantitatively analyzed to assess both the RNVs area and leakage area. On OCT-A RNVs area, vascular perfusion density (VPD), vessel length density ...
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      Mentions: University of Pittsburgh Gabriel J. Coscas

    4. BG-CNN: A Boundary Guided Convolutional Neural Network for Corneal Layer Segmentation from Optical Coherence Tomography

      Explore ACM Digital Library Ophthalmology
      BG-CNN: A Boundary Guided Convolutional Neural Network for Corneal Layer Segmentation from Optical Coherence Tomography
      Precise segmentation of corneal layers depicted on optical coherence tomography (OCT) images plays an important role in detecting corneal diseases, such as keratoconus and dry eye. In this study, we present a boundary guided convolutional neural network (BG-CNN) to extract different corneal layers. The developed network uses three convolutional blocks to construct two network modules derived from the classical U-Net network. This network was trained based on a dataset consisting ...
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      Mentions: University of Pittsburgh Wenzhou Medical College Meixiao Shen

    5. Measuring 3D Optic Nerve Head Deformations using Digital Volume Correlation of in vivo Optical Coherence Tomography Data (Thesis)

      Explore Welcome to D Ophthalmology , Student Theses
      Measuring 3D Optic Nerve Head Deformations using Digital Volume Correlation of in vivo Optical Coherence Tomography Data (Thesis)
      The optic nerve head (ONH), located in the back of the eye, is a critical site in understanding the pathophysiology of glaucoma. However, longitudinal changes of the ONH as disease develops have not been well characterized. Our goal was to develop an improved tool to quantify these changes in an in vivo monkey model of glaucoma. Longitudinal spectral-domain optical coherence tomography (OCT) imaging of the ONH was performed every other ...
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      Mentions: University of Pittsburgh

    6. Assessment Of Central Serous Chorioretinopathy Depicted On Color Fundus Photographs Using Deep Learning

      Explore LWW Online Ophthalmology
      Assessment Of Central Serous Chorioretinopathy Depicted On Color Fundus Photographs Using Deep Learning
      Purpose: To investigate whether and to what extent central serous chorioretinopathy ( CSC ) depicted on color fundus photographs can be assessed using deep learning technology. Methods: We collected a total of 2,504 fundus images acquired on different subjects. We verified the CSC status of these images using their corresponding optical coherence tomography images. A total of 1,329 images depicted CSC . These images were preprocessed and normalized. This resulting data ...
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      Mentions: University of Pittsburgh

    7. Curved-field optical coherence tomography: large-field imaging of human corneal cells and nerves

      Explore OSA | OSA Publishing Ophthalmology
      Curved-field optical coherence tomography: large-field imaging of human corneal cells and nerves
      Cell-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers, and the view of each layer is reduced. Here we present curved-field optical coherence tomography, capable of capturing optical sections of arbitrary curvature. We test the device on a challenging task of imaging the human cornea in ...
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      Mentions: University of Pittsburgh Michel Pâques Claude Boccara

    8. Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study

      Explore SAGE Journals Ophthalmology
      Optical coherence tomography angiography findings of fellow eye of proliferative macular telangiectasia type 2: Long term study
      Purpose: To report the characteristics of non-proliferative fellow eyes in patients with unilateral proliferative macular telangiectasia type 2 (MacTel). Methods: This was a multicenter, retrospective study and included fellow eyes of eyes with subretinal neovascular membrane (SRNVM). Multimodal imaging including fundus photography, optical coherence tomography (OCT), and OCT angiography (OCTA) was performed. OCT and OCTA measurements included central macular thickness (CMT), subfoveal choroidal thickness (SFCT), foveal avascular zone (FAZ) area ...
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      Mentions: University of Pittsburgh L V Prasad Eye Institute University of Sydney

    9. University of Pittsburg Receives NIH Grant for Three Dimensional nanoscale Nuclear Architecture Mapping based Taxonomy of Precursor Lesions for Predicting Colorectal Cancer Risk

      Explore Optical Coherence Tomography News Gastroenterology , Oncology
      University of Pittsburg Receives NIH Grant for Three Dimensional nanoscale Nuclear Architecture Mapping based Taxonomy of Precursor Lesions for Predicting Colorectal Cancer Risk
      University of Pittsburg Receives a 2020 NIH Grant for $437,317 for Three Dimensional nanoscale Nuclear Architecture Mapping based Taxonomy of Precursor Lesions for Predicting Colorectal Cancer Risk. The principal investigator is Yang Liu. Below is a summary of the proposed work. The effectiveness of colorectal cancer (CRC) screening, with a concomitant increased emphasis on detection of even the smallest adenomas, has resulted in a new clinical challenge. An increased ...
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      Mentions: University of Pittsburgh National Institutes of Health

    10. Efficacy of navigated focal laser photocoagulation in diabetic macular edema planned with en face optical coherence tomography versus fluorescein angiography

      Explore Home - Springer Ophthalmology
      Efficacy of navigated focal laser photocoagulation in diabetic macular edema planned with en face optical coherence tomography versus fluorescein angiography
      Aim To analyze the efficacy of navigated focal laser photocoagulation (FLP) of microaneurysms in diabetic macular edema (DME) planned using en face optical coherence tomography (OCT) as against fluorescein angiography (FA). Methods Twenty-six eyes of 21 DME patients (12 males, 9 females, 69.512.3 years) with mean BCVA of 0.520.44 LogMAR were included. En face OCT images of deep capillary plexus slab and FA images were used ...
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      Mentions: University of Pittsburgh

    12. Mapping of internal features on en face imagery

      Explore uspto.gov Ophthalmology , Patents
      Mapping of internal features on en face imagery
      The present disclosure describes systems and method for generating surgical maps that provide a surgeon with information regarding the placement of features of interest. More particularly, the system is configured to display optical coherence tomography (OCT) images to a medical professional. The medical professional can select anatomical features, biomarkers, and other features of interest within each of the OCT images. The system can then translate the location of the features ...
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      Mentions: University of Pittsburgh Joel S. Schuman Larry Kagemann

    13. Analysis of Choroidal Vascularity Index in Keratoconus Patients Using Swept-Source Optical Coherence Tomography-Based Binarization Techniques

      Explore Hindawi Publishing Corporation Ophthalmology
      Analysis of Choroidal Vascularity Index in Keratoconus Patients Using Swept-Source Optical Coherence Tomography-Based Binarization Techniques
      Purpose . To analyse the vascular density of the choroid in a keratoconus (KC) population using swept-source optical coherence tomography (SS-OCT). Methods . Prospective, noninterventional study that analysed 97 eyes from 52 KC patients and 145 eyes from 89 healthy controls. The sample was divided in four different age groups. Inclusion criteria were topographic diagnosis of KC using Pentacam, axial length shorter than 26mm, good quality of the images, and no other ...
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      Mentions: University of Pittsburgh

    14. Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids

      Explore arxiv.org Ophthalmology
      Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids
      Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced pluripotent stem cell-derived retinal organoids non-invasively. Colored images with an endogenous contrast linked to organelle motility are generated, with sub-micrometer spatial resolution and millisecond temporal resolution, opening an avenue to identify specific cell types in living tissue via their function.
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      Mentions: University of Pittsburgh Claude Boccara ESPCI ParisTech

    15. Pre-, Intra-, and Post-Operative Evaluation of Extraocular Muscle Insertions Using Optical Coherence Tomography: A Comparison of Four Devices

      Explore MDPI Open Access Journals Platform Ophthalmology
      Pre-, Intra-, and Post-Operative Evaluation of Extraocular Muscle Insertions Using Optical Coherence Tomography: A Comparison of Four Devices
      OCT (optical coherence tomography) is widely used in ophthalmology and pediatric ophthalmology, but limited research has been done on the use of OCT in strabismus. This study investigates the use of different OCT machines to image rectus muscle insertions pre-, intra-, and post-operatively in pediatric strabismus patients. The OCT machines used in the study were a Bioptigen (Leica Microsystems Inc., Buffalo Grove, IL, USA), Spectralis HRA+OCT with Anterior Segment ...
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      Mentions: University of Pittsburgh Heidelberg Engineering Carl Zeiss Meditec

    16. NEW OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS ON AN INTRARETINAL VASCULAR PROCESS SECONDARY TO TOXOPLASMA RETINOCHOROIDITIS 2 CASE REPORTS

      Explore LWW Online Ophthalmology
      NEW OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FINDINGS ON AN INTRARETINAL VASCULAR PROCESS SECONDARY TO TOXOPLASMA RETINOCHOROIDITIS 2 CASE REPORTS
      Background/Purpose: To determine which retinal layer is primarily involved in intraretinal vascular processes associated with Toxoplasma retinochoroiditis using multimodal imaging, including optical coherence tomography angiography ( OCTA ). Methods: Toxoplasma retinal lesions were analyzed through multimodal imaging, including color fundus photographs, fluorescein angiography, indocyanine green angiography, spectral-domain OCT, and OCTA . Results: Two patients with atypical features of Toxoplasma retinochoroiditis are described in the acute phase. The first patient presented with a ...
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      Mentions: University of Pittsburgh
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  4. About University of Pittsburgh

    University of Pittsburgh

    University of Pittsburgh public research university located in Pittsburgh, Pennsylvania. Pitt is a renowned leader in academic fields as diverse as philosophy and medicine.  University of Pittsburgh Medical Center has a team of about 50,000 employees, UPMC serves the health needs of more than 4 million people each year  Department of Ophthalmology UPMC Eye Center’s mission is to improve quality of life through the preservation and restoration of vision.  Swanson School of Engineering is the engineering school of the University of Pittsburgh in Pittsburgh, Pennsylvania.

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