1. University of Pittsburgh

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    1. Mentioned In 199 Articles

    2. Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma

      Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma
      Background The study aims to correlate Fourier-domain optical coherence tomography (FD-OCT) with Goldmann visual field (GVF) to show the photoreceptor (PR) structure and function relationship in the first described case of cancer-associated retinopathy (CAR) from Merkel cell carcinoma. Findings A case study of a patient with CAR who was imaged with serial GVF and FD-OCT over a 2-year period was carried out. En face images were created using a custom ...
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    3. In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT

      In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT
      Purpose. Excitotoxicity has been linked to the pathogenesis of ocular diseases and injuries and may involve early degeneration of both anterior and posterior visual pathways. However, their spatiotemporal relationships remain unclear. We hypothesized that the effects of excitotoxic retinal injury (ERI) on the visual system can be revealed in vivo by diffusion tensor magnetic resonance imagining (DTI), manganese-enhanced magnetic resonance imagining (MRI), and optical coherence tomography (OCT). Methods. Diffusion tensor ...
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    4. Advanced Imaging Techniques for the Pathologist

      Advanced Imaging Techniques for the Pathologist
      Advanced imaging refers to direct microscopic imaging of tissue, without the need for traditional hematoxylin-eosin (HE) microscopy, including microscope slides or whole-slide images. A detailed example is presented of optical coherence tomography (OCT), an imaging technique based on reflected light. Experience and example images are discussed in the larger context of the evolving relationship of surgical pathology to clinical patient care providers. Although these techniques are diagnostically promising, it is ...
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    5. Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images

      Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images
      Purpose. We minimized the influence of image quality variability, as measured by signal strength (SS), on optical coherence tomography (OCT) thickness measurements using the histogram matching (HM) method. Methods. We scanned 12 eyes from 12 healthy subjects with the Cirrus HD-OCT device to obtain a series of OCT images with a wide range of SS (maximal range, 110) at the same visit. For each eye, the histogram of an image ...
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    6. Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography
      ...borative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imagi...
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    7. Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second
      ..., MA, 02139, United States 5. ^5Department of Ophthalmology, University of Pittsburgh School of Medicine, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Pittsburgh, PA, 1521...
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    8. Full-field optical coherence tomography (FFOCT) for evaluation of endometrial cancer

      Full-field optical coherence tomography (FFOCT) for evaluation of endometrial cancer
      Full-field optical coherence tomography (FFOCT) quickly produces images that resemble conventional pathology images. We examined endometrium in an intra-operative like fashion (more than forty samples). FFOCT-imaged endometrium was recognizable to pathologists and compared favorably with microscopy of the same samples. Additional image enhancements and acquisition techniques were explored and may improve interpretation accuracy. Wider evaluation of images is ongoing, using more pathologist subjects. FFOCT may revolutionize pathology practice in the ...
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    9. Evaluating glaucoma damage: emerging imaging technologies

      Evaluating glaucoma damage: emerging imaging technologies
      The use of ocular imaging tools to estimate structural and functional damage in glaucoma has become a common clinical practice and a substantial focus of vision research. The evolution of the imaging technologies through increased scanning speed, penetration depth, image registration and development of multimodal devices has the potential to detect the pathology more reliably and in earlier stages. This review is focused on new ocular imaging modalities used for ...
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    10. New developments in optical coherence tomography

      New developments in optical coherence tomography
      Purpose of review: Optical coherence tomography (OCT) has become the cornerstone technology for clinical ocular imaging in the past few years. The technology is still rapidly evolving with newly developed applications. This manuscript reviews recent innovative OCT applications for glaucoma diagnosis and management. Recent findings: The improvements made in the technology have resulted in increased scanning speed, axial and transverse resolution, and more effective use of the OCT technology as ...
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    11. Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison

      Advanced Imaging for Glaucoma Study: Design, Baseline Characteristics, and Inter-Site Comparison
      Purpose To report the baseline characteristics of the participants in the Advanced Imaging for Glaucoma Study. To compare the participating sites for variations among subjects and the performance of imaging instruments. Design Multi-center longitudinal observational cohort study Methods A total of 788 participants (1,329 eyes) were enrolled from three academic referral centers. There were 145 participants (289 eyes) in the normal group, 394 participants (663 eyes) in the glaucoma ...
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    12. In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography

      In Vivo Three-Dimensional Characterization of the Healthy Human Lamina Cribrosa with Adaptive Optics Spectral-Domain Optical Coherence Tomography
      ...h, PA, 15213, United States 1. ↵* Department of Ophthalmology, University of Pittsburgh School of Medicine, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Pittsburgh, PA, 1521...
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    13. Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages

      Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages
      ...ogy, Medical University of Vienna, Währinger Straße 13, Vienna 1090, Austria ^3Department of Ophthalmology, University of Pittsburgh, Eye & Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, USA ^4Department of...
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    14. Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study

      Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study
      Objectives: This study aimed to compare the effect of bivalirudin and unfractionated heparin (UFH) on residual thrombus burden assessed by frequency-domain optical coherence tomography (FD-OCT), and on angiographic indices of microvascular obstruction (MVO). Background: The efficacy of bivalirudin to inhibit thrombus formation inside the stent during percutaneous coronary interventions (PCI) as compared to UFH is unknown. Methods: Sixty patients with coronary artery disease who underwent post-PCI FD-OCT were studied, including ...
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    15. Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study

      Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study
      Background The relationship between features of vulnerable plaque and angiographic coronary stenosis is unknown. Objectives The purpose of this study was to systematically investigate the absolute number, relative prevalence, and characteristics of thin-cap fibroatheroma (TCFA) at different degrees of stenosis using optical coherence tomography (OCT), intravascular ultrasound, and coronary angiography. Methods We identified 643 plaques from 255 subjects who underwent OCT imaging in all 3 coronary arteries. They were divided ...
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    16. 1-15 of 199 1 2 3 4 ... 12 13 14 »
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  2. About University of Pittsburgh

    University of Pittsburgh

    University of Pittsburgh public research university located in Pittsburgh, Pennsylvania. Pitt is a renowned leader in academic fields as diverse as philosophy and medicine.  University of Pittsburgh Medical Center has a team of about 50,000 employees, UPMC serves the health needs of more than 4 million people each year  Department of Ophthalmology UPMC Eye Center’s mission is to improve quality of life through the preservation and restoration of vision.  Swanson School of Engineering is the engineering school of the University of Pittsburgh in Pittsburgh, Pennsylvania.