1. University of Pittsburgh

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    1. Mentioned In 207 Articles

    2. Optical Coherence Tomography Imaging of the Palisades of Vogt to Assist Clinical Evaluation and Surgical Planning in a Case of Limbal Stem-Cell Deficiency

      Optical Coherence Tomography Imaging of the Palisades of Vogt to Assist Clinical Evaluation and Surgical Planning in a Case of Limbal Stem-Cell Deficiency
      PURPOSE: To describe the use of volumetric optical coherence tomography (OCT) imaging to assist evaluation of a patient referred for autologous limbal stem-cell transplant. METHODS: This is a case report of a 50-year-old patient presenting with unilateral limbal stem-cell deficiency who was referred for autologous limbal stem-cell transplant. The presence of Salzmann nodules in the donor eye raised questions about the efficacy of transplantation, prompting examination of both eyes using ...
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    3. Virtual Averaging Making Nonframe-Averaged Optical Coherence Tomography Images Comparable to Frame-Averaged Images

      Virtual Averaging Making Nonframe-Averaged Optical Coherence Tomography Images Comparable to Frame-Averaged Images
      Purpose : Developing a novel image enhancement method so that nonframe-averaged optical coherence tomography (OCT) images become comparable to active eye-tracking frame-averaged OCT images. Methods : Twenty-one eyes of 21 healthy volunteers were scanned with noneye-tracking nonframe-averaged OCT device and active eye-tracking frame-averaged OCT device. Virtual averaging was applied to nonframe-averaged images with voxel resampling and adding amplitude deviation with 15-time repetitions. Signal-to-noise (SNR), contrast-to-noise ratios (CNR), and the distance between the ...
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    4. IMAGING WITH MULTIMODAL ADAPTIVE-OPTICS OPTICAL COHERENCE TOMOGRAPHY IN MULTIPLE EVANESCENT WHITE DOT SYNDROME: THE STRUCTURE AND FUNCTIONAL RELATIONSHIP

      IMAGING WITH MULTIMODAL ADAPTIVE-OPTICS OPTICAL COHERENCE TOMOGRAPHY IN MULTIPLE EVANESCENT WHITE DOT SYNDROME: THE STRUCTURE AND FUNCTIONAL RELATIONSHIP
      Purpose: To elucidate the location of pathological changes in multiple evanescent white dot syndrome (MEWDS) with the use of multimodal adaptive optics (AO) imaging . Methods: A 5-year observational case study of a 24-year-old female with recurrent MEWDS. Full examination included history, Snellen chart visual acuity, pupil assessment, intraocular pressures, slit lamp evaluation, dilated fundoscopic exam, imaging with Fourier-domain optical coherence tomography (FD-OCT), blue-light fundus autofluorescence (FAF), fundus photography, fluorescein angiography ...
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    5. Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center

      Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center
      ...chool of Medicine, where he was a distinguished professor and chair of ophthalmology, and the director of the UPMC Eye Center. Dr. Schuman also held appointments at the university's McGowan Institute for Regenerative Med...
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    6. Feasibility of Spectral Domain Optical Coherence Tomography Acquisition Using a Handheld Versus Conventional Tabletop Unit

      Feasibility of Spectral Domain Optical Coherence Tomography Acquisition Using a Handheld Versus Conventional Tabletop Unit
      Purpose: Patients afflicted with ocular complications of diabetes represent a diverse demographic who often cannot undergo spectral-domain optical coherence tomography (SD-OCT) imaging of the retina due to postural restraints. Our pilot study compared imaging acquisition methods using SD-OCT in the handheld (HH) mode versus the conventional tabletop (TT) method. Methods: Our study included 22 undilated eyes of 22 subjects (mean SD age, 35.8 16.8 years) imaged using HH ...
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    7. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography

      Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography
      Purpose To predict the development of glaucomatous visual field (VF) defects using Fourier-domain optical coherence tomography (FD-OCT) measurements at baseline visit. Design Multi-center longitudinal observational study. Glaucoma suspects and pre-perimetric glaucoma participants in the Advanced Imaging for Glaucoma Study. Methods The optic disc, the peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) were imaged with FD-OCT VF was assessed every 6 months. Conversion to perimetric glaucoma ...
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    8. Fourier phase in Fourier-domain optical coherence tomography

      Fourier phase in Fourier-domain optical coherence tomography
      Phase of an electromagnetic wave propagating through a sample-of-interest is well understood in the context of quantitative phase imaging in transmission-mode microscopy. In the past decade, Fourier-domain optical coherence tomography has been used to extend quantitative phase imaging to the reflection-mode. Unlike transmission-mode electromagnetic phase, however, the origin and characteristics of reflection-mode Fourier phase are poorly understood, especially in samples with a slowly varying refractive index. In this paper, the ...
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    9. Identification of Intrastent Pathology Associated With Late Stent Thrombosis Using Optical Coherence Tomography

      Identification of Intrastent Pathology Associated With Late Stent Thrombosis Using Optical Coherence Tomography
      Objective To better characterize intrastent pathology using optical coherence tomography (OCT) in patients presenting with late and very late stent thrombosis (LST/VLST). Background The contribution of specific intrastent pathologies to the development of LST/VLST is not well understood. Methods In this single-center, retrospective, observational study of 796 consecutive patients treated for ST-segment elevation myocardial infarction (STEMI) with primary PCI we identified 57 patients (7.2%) in whom STEMI ...
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    10. Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma

      Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma
      Background The study aims to correlate Fourier-domain optical coherence tomography (FD-OCT) with Goldmann visual field (GVF) to show the photoreceptor (PR) structure and function relationship in the first described case of cancer-associated retinopathy (CAR) from Merkel cell carcinoma. Findings A case study of a patient with CAR who was imaged with serial GVF and FD-OCT over a 2-year period was carried out. En face images were created using a custom ...
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    11. In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT

      In Vivo Evaluation of White Matter Integrity and Anterograde Transport in Visual System After Excitotoxic Retinal Injury With Multimodal MRI and OCT
      Purpose. Excitotoxicity has been linked to the pathogenesis of ocular diseases and injuries and may involve early degeneration of both anterior and posterior visual pathways. However, their spatiotemporal relationships remain unclear. We hypothesized that the effects of excitotoxic retinal injury (ERI) on the visual system can be revealed in vivo by diffusion tensor magnetic resonance imagining (DTI), manganese-enhanced magnetic resonance imagining (MRI), and optical coherence tomography (OCT). Methods. Diffusion tensor ...
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    12. Advanced Imaging Techniques for the Pathologist

      Advanced Imaging Techniques for the Pathologist
      Advanced imaging refers to direct microscopic imaging of tissue, without the need for traditional hematoxylin-eosin (HE) microscopy, including microscope slides or whole-slide images. A detailed example is presented of optical coherence tomography (OCT), an imaging technique based on reflected light. Experience and example images are discussed in the larger context of the evolving relationship of surgical pathology to clinical patient care providers. Although these techniques are diagnostically promising, it is ...
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    13. Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images

      Histogram Matching Extends Acceptable Signal Strength Range on Optical Coherence Tomography Images
      Purpose. We minimized the influence of image quality variability, as measured by signal strength (SS), on optical coherence tomography (OCT) thickness measurements using the histogram matching (HM) method. Methods. We scanned 12 eyes from 12 healthy subjects with the Cirrus HD-OCT device to obtain a series of OCT images with a wide range of SS (maximal range, 110) at the same visit. For each eye, the histogram of an image ...
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    14. Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Massachusetts Institute of Technology Received a 2015 NIH Grant for Novel Diagnostics with Optical Coherence Tomography
      ...borative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imagi...
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    15. Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second
      ..., MA, 02139, United States 5. ^5Department of Ophthalmology, University of Pittsburgh School of Medicine, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Pittsburgh, PA, 1521...
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    16. 1-15 of 207 1 2 3 4 ... 12 13 14 »
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  2. About University of Pittsburgh

    University of Pittsburgh

    University of Pittsburgh public research university located in Pittsburgh, Pennsylvania. Pitt is a renowned leader in academic fields as diverse as philosophy and medicine.  University of Pittsburgh Medical Center has a team of about 50,000 employees, UPMC serves the health needs of more than 4 million people each year  Department of Ophthalmology UPMC Eye Center’s mission is to improve quality of life through the preservation and restoration of vision.  Swanson School of Engineering is the engineering school of the University of Pittsburgh in Pittsburgh, Pennsylvania.