1. University of Pittsburgh

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    1. Mentioned In 186 Articles

    2. Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages

      Dual modality optical coherence and whole-body photoacoustic tomography imaging of chick embryos in multiple development stages
      ...ogy, Medical University of Vienna, Währinger Straße 13, Vienna 1090, Austria ^3Department of Ophthalmology, University of Pittsburgh, Eye & Ear Institute, 203 Lothrop Street, Pittsburgh, PA 15213, USA ^4Department of...
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    3. Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study

      Bivalirudin versus unfractionated heparin for residual thrombus burden: A frequency-domain optical coherence tomography study

      Objectives: This study aimed to compare the effect of bivalirudin and unfractionated heparin (UFH) on residual thrombus burden assessed by frequency-domain optical coherence tomography (FD-OCT), and on angiographic indices of microvascular obstruction (MVO). Background: The efficacy of bivalirudin to inhibit thrombus formation inside the stent during percutaneous coronary interventions (PCI) as compared to UFH is unknown. Methods: Sixty patients with coronary artery disease who underwent post-PCI FD-OCT were studied, including 20 patients treated with bivalirudin and 40 control patients treated with UFH, matched by clinical presentation, stent characteristics, and periprocedural medications. In-stent thrombus volume, thrombus score (number of quadrants with ...

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    4. Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study

      Prevalence and Characteristics of TCFA and Degree of Coronary Artery Stenosis An OCT, IVUS, and Angiographic Study

      Background The relationship between features of vulnerable plaque and angiographic coronary stenosis is unknown. Objectives The purpose of this study was to systematically investigate the absolute number, relative prevalence, and characteristics of thin-cap fibroatheroma (TCFA) at different degrees of stenosis using optical coherence tomography (OCT), intravascular ultrasound, and coronary angiography. Methods We identified 643 plaques from 255 subjects who underwent OCT imaging in all 3 coronary arteries. They were divided into 3 groups on the basis of angiographic diameter stenosis: Group A (30% to 49%, n = 325), Group B (50% to 69%, n = 227), and Group C (>70%, n = 91 ...

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    5. Intra- and Inter-visit Reproducibility of Ganglion Cell – Inner Plexiform Layer Measurements Using Handheld Optical Coherence Tomography in Children with Optic Pathway Gliomas

      Intra- and Inter-visit Reproducibility of Ganglion Cell – Inner Plexiform Layer Measurements Using Handheld Optical Coherence Tomography in Children with Optic Pathway Gliomas

      Purpose To determine the intra- and inter-visit reproducibility of ganglion cell-inner plexiform layer thickness measures using handheld optical coherence tomography (OCT) in sedated children with optic pathway gliomas and/or Neurofibromatosis type 1 (NF1). Design Prospective longitudinal cohort study Methods Children with sporadic optic pathway gliomas and/or NF1 who had ≥ 2 volumes acquired over the macula using handheld OCT during sedation for a clinically indicated MRI were eligible for the intra-visit cohort. Children with repeat handheld OCT imaging within 6 months were eligible for the inter-visit cohort. Total retinal thickness and ganglion cell-inner plexiform layer thickness were measured using ...

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    6. Reproducibility of Circumpapillary Retinal Nerve Fiber Layer Measurements Using Handheld Optical Coherence Tomography in Sedated Children

      Reproducibility of Circumpapillary Retinal Nerve Fiber Layer Measurements Using Handheld Optical Coherence Tomography in Sedated Children
      ...Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA * Department of Bioengineering, Swanson School o...
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    7. University of Pittsburgh Receives NIH Grant for Microsurgical In-Situ Image Guidance With Optical Coherence Tomography

      University of Pittsburgh Receives NIH Grant for Microsurgical In-Situ Image Guidance With Optical Coherence Tomography
      ...ents. We expect to write a competitive renewal for such trials during the final year of the current proposal. University of Pittsburgh Receives a 2014 NIH Grant for $542,064 for Microsurgical In-Situ Image Guidance With ...
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    8. Automated macular pathology diagnosis in three-dimensional (3D) spectral domain optical coherence tomography (SD-OCT) images

      Automated macular pathology diagnosis in three-dimensional (3D) spectral domain optical coherence tomography (SD-OCT) images

      Systems and methods of analyzing an optical coherence tomography image of a retina are discussed. A 2-dimensional slice of the image can be aligned to produce an approximately horizontal image of the retina and an edge map based at least in part on the aligned slice. Also, at least one global representation can be determined based on a (multi-scale) spatial division, such as multi-scale spatial pyramid, on the slice and/or edge map. Creating the local features is based on the specified cell structure of the global representation. The local features can be constructed based on local binary pattern (LBP ...

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    9. Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study

      Spatial Heterogeneity of Neoatherosclerosis, and its Relationship with Neovascularization and Adjacent Plaque Characteristics: Optical Coherence Tomography Study
      ...lar Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN , * Catalin Toma, MD Affiliations + University of Pittsburgh Medical Center, Pittsburgh, PA , * Haibo Jia, MD, PhD Affiliations + Department of Ca...
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    10. A Method to Estimate Biomechanics and Mechanical Properties of Optic Nerve Head Tissues From Parameters Measurable Using Optical Coherence Tomography

      A Method to Estimate Biomechanics and Mechanical Properties of Optic Nerve Head Tissues From Parameters Measurable Using Optical Coherence Tomography

      Tissue properties and biomechanics of the optic nerve head (ONH) are important to the development and progression of glaucoma, but remain mostly unmeasurable in the experiment. We hypothesized that these can be estimated numerically from ocular parameters measurable in-vivo with optical coherence tomography (OCT). Using previously reported parametric models representing human ONHs we simulated acute intraocular pressure (IOP) increases (10 mmHg). Statistical models were fit to predict, from OCT-measurable parameters, 15 outputs of interest including tissue properties, stresses and deformations. The calculations were repeated adding parameters that have recently been proposed as potentially measurable with OCT. We evaluated the sensitivity ...

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    11. International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014

      International Workshop on Tissue Phantoms and Standardization in Biophotonics at University of Maryland, May 21, 2014
      ...ermany Vassilis Ntziachristos, Technische Universität München, Germany Maritoni Litorja, NIST Gadi Wollstein, University of Pittsburgh School of Medicine The conference will be held at the University of Maryland College...
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  2. About University of Pittsburgh

    University of Pittsburgh

    University of Pittsburgh public research university located in Pittsburgh, Pennsylvania. Pitt is a renowned leader in academic fields as diverse as philosophy and medicine.  University of Pittsburgh Medical Center has a team of about 50,000 employees, UPMC serves the health needs of more than 4 million people each year  Department of Ophthalmology UPMC Eye Center’s mission is to improve quality of life through the preservation and restoration of vision.  Swanson School of Engineering is the engineering school of the University of Pittsburgh in Pittsburgh, Pennsylvania.