1. University of Pittsburgh

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    1. Mentioned In 226 Articles

    2. In vivo high resolution human corneal imaging using full-field optical coherence tomography

      Explore OSA | OSA Publishing Ophthalmology
      In vivo high resolution human corneal imaging using full-field optical coherence tomography
      We present the first full-field optical coherence tomography (FFOCT) device capable of in vivo imaging of the human cornea. We obtained images of the epithelial structures, Bowmans layer, sub-basal nerve plexus (SNP), anterior and posterior stromal keratocytes, stromal nerves, Descemets membrane and endothelial cells with visible nuclei. Images were acquired with a high lateral resolution of 1.7 m and relatively large field-of-view of 1.26 mm x 1.26 ...
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      Mentions: University of Pittsburgh Johns Hopkins University Claude Boccara

    3. Signal normalization among multiple optical coherence tomography devices

      Explore uspto.gov Patents
      Signal normalization among multiple optical coherence tomography devices
      The present disclosure is directed to systems and methods for normalizing an image of an eye among multiple optical coherence tomography (OCT) devices. The system can receive an OCT image and generate a normalized OCT image. The system is configured to normalize a sample density of the received image, normalize an amount of noise using a suitable noise reduction technique, normalize a distribution of signal amplitudes of the image, and ...
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      Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein

    4. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study

      Explore ScienceDirect Cardiology
      Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
      Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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      Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto

    5. Intraoperative Optical Coherence Tomography-Assisted Descemet Stripping Automated Endothelial Keratoplasty for Anterior Chamber Fibrous Ingrowth

      Explore insights.ovid.com Ophthalmology
      Intraoperative Optical Coherence Tomography-Assisted Descemet Stripping Automated Endothelial Keratoplasty for Anterior Chamber Fibrous Ingrowth
      Purpose: Here, we present the first reported case of intraoperative optical coherence tomography (OCT)-assisted Descemet membrane stripping automated endothelial keratoplasty (DSAEK) in a patient with anterior segment fibrous ingrowth. Methods: A 61-year-old woman with corneal edema and chronic angle-closure glaucoma secondary to fibrous ingrowth after 2 glaucoma shunt device implantations underwent dissection and removal of anterior chamber fibrous ingrowth and DSAEK. The surgical techniques using intraoperative OCT and outcome ...
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      Mentions: University of Pittsburgh

    6. MIT Receives a 2017 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      Explore Optical Coherence Tomography News Funding
      MIT Receives a 2017 NIH Grant for Novel Diagnostics with Optical Coherence Tomography
      ...borative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye Center. This is a multidisciplinary program which integrates imagi...
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      Mentions: University of Pittsburgh Massachusetts Institute of Technology National Institutes of Health

    7. Signal Normalization Reduces Image Appearance Disparity Among Multiple Optical Coherence Tomography Devices

      Explore TVST Journal Ophthalmology
      Signal Normalization Reduces Image Appearance Disparity Among Multiple Optical Coherence Tomography Devices
      Purpose : To assess the effect of the previously reported optical coherence tomography (OCT) signal normalization method on reducing the discrepancies in image appearance among spectral-domain OCT (SD-OCT) devices. Methods : Healthy eyes and eyes with various retinal pathologies were scanned at the macular region using similar volumetric scan patterns with at least two out of three SD-OCT devices at the same visit (Cirrus HD-OCT, Zeiss, Dublin, CA; RTVue, Optovue, Fremont, CA ...
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      Mentions: University of Pittsburgh Optovue Heidelberg Engineering

    8. Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures

      Explore Conference Proceedings Neurology , Ophthalmology
      Mapping in-vivo optic nerve head strains caused by intraocular and intracranial pressures
      Although it is well documented that abnormal levels of either intraocular (IOP) or intracranial pressure (ICP) can lead to potentially blinding conditions, such as glaucoma and papilledema, little is known about how the pressures actually affect the eye. Even less is known about potential interplay between their effects, namely how the level of one pressure might alter the effects of the other. Our goal was to measure in-vivo the pressure-induced ...
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      Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein

    9. Adaptive optics optical coherence tomography in glaucoma

      Explore ScienceDirect Ophthalmology
      Adaptive optics optical coherence tomography in glaucoma
      Since the introduction of commercial optical coherence tomography (OCT) systems, the ophthalmic imaging modality has rapidly expanded and it has since changed the paradigm of visualization of the retina and revolutionized the management and diagnosis of neuro-retinal diseases, including glaucoma. OCT remains a dynamic and evolving imaging modality, growing from time-domain OCT to the improved spectral-domain OCT, adapting novel image analysis and processing methods, and onto the newer swept-source OCT ...
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      Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein

    10. Establishing compatibility between two- and three-dimensional optical coherence tomography scans

      Explore uspto.gov Ophthalmology , Patents
      Establishing compatibility between two- and three-dimensional optical coherence tomography scans
      Advances in optical coherence tomography (OCT) have prompted a transition from time domain OCT, providing 2D OCT images, to spectral domain OCT, which has a 3D imaging capability. Yet conventional technology offers little toward the goal of inter-device compatibility between extant 2D OCT images and newer 3D OCT images for the same or comparable subjects, as in the context of ongoing monitoring the quantitative status of a patient's eyes ...
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      Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein

    12. Failure Mechanisms and Neoatherosclerosis Patterns in Very Late Drug-Eluting and Bare-Metal Stent Thrombosis

      Explore Circulation Cardiology
      Failure Mechanisms and Neoatherosclerosis Patterns in Very Late Drug-Eluting and Bare-Metal Stent Thrombosis
      Background There are few clinical studies on the pathophysiological mechanisms of very late stent thrombosis (VLST). We report optical coherence tomography findings in patients with VLST and compare the findings between bare-metal stents (BMS) and drug-eluting stents (DES). Methods and Results We conducted a registry of stent thrombosis at 4 North American centers with optical coherence tomography imaging programs SAFE registry (The Study of Late Stent Failure Evaluated by OCT ...
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      Mentions: University of Pittsburgh Case Western Reserve University University of British Columbia

    13. Clinical Utility of Optical Coherence Tomography in Glaucoma

      Explore IOVS Journal Ophthalmology
      Clinical Utility of Optical Coherence Tomography in Glaucoma
      Optical coherence tomography (OCT) has established itself as the dominant imaging modality in the management of glaucoma and retinal diseases, providing high-resolution visualization of ocular microstructures and objective quantification of tissue thickness and change. This article reviews the history of OCT imaging with a specific focus on glaucoma. We examine the clinical utility of OCT with respect to diagnosis and progression monitoring, with additional emphasis on advances in OCT technology ...
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      Mentions: University of Pittsburgh Joel S. Schuman Gadi Wollstein

    14. Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

      Explore IOVS Journal Ophthalmology
      Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices
      Purpose : Optical coherence tomography (OCT) can monitor for glaucoma by measuring dimensions of the optic nerve head (ONH) cup and disc. Multiple clinical studies have shown that different OCT devices yield different estimates of retinal dimensions. We developed phantoms mimicking ONH morphology as a new way to compare ONH measurements from different clinical OCT devices. Methods : Three phantoms were fabricated to model the ONH: One normal and two with glaucomatous ...
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      Mentions: University of Pittsburgh Joel S. Schuman Daniel X. Hammer
    17. 1-15 of 226 1 2 3 4 ... 13 14 15 »
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  4. About University of Pittsburgh

    University of Pittsburgh

    University of Pittsburgh public research university located in Pittsburgh, Pennsylvania. Pitt is a renowned leader in academic fields as diverse as philosophy and medicine.  University of Pittsburgh Medical Center has a team of about 50,000 employees, UPMC serves the health needs of more than 4 million people each year  Department of Ophthalmology UPMC Eye Center’s mission is to improve quality of life through the preservation and restoration of vision.  Swanson School of Engineering is the engineering school of the University of Pittsburgh in Pittsburgh, Pennsylvania.

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