1. University of Perugia

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    1. Mentioned In 17 Articles

    2. In-vivo visualization of the photoreceptors using Spectralis High Magnification Module imaging in central serous chorioretinopath

      In-vivo visualization of the photoreceptors using Spectralis High Magnification Module imaging in central serous chorioretinopath
      Purpose To visualize photoreceptors using the Spectralis High Magnification Module (HMM) in a case of central serous chorioretinopathy (CSCR) and to correlate the findings with those of optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A). Observations A 35-year-old Caucasian male presenting with chronic CSCR in the left eye was examined using HMM, OCT and OCT-A. The photoreceptors mosaic was assessed both in diseased and apparently uninvolved areas. A ...
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    3. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY EVALUATION OF PERIPAPILLARY MICROVASCULAR CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY EVALUATION OF PERIPAPILLARY MICROVASCULAR CHANGES AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR
      Purpose: To evaluate the radial peripapillary capillary plexus (RPCP) vessel density (VD) and the retinal nerve fiber layer (RNFL) thickness in eyes successfully treated with pars plana vitrectomy for primary rhegmatogenous retinal detachment. Methods: In this cross-sectional multicenter clinical study, eyes with a minimum 12-month follow-up were reexamined. The RPCP VD and RNFL thickness in the rhegmatogenous retinal detachment subfields of the affected eye (study group) were compared with the ...
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    4. Wide-field optical coherence tomography imaging in diabetic retinopathy

      Wide-field optical coherence tomography imaging in diabetic retinopathy
      Purpose: To report the individual retinal layer thicknesses up to mid-equator in patients with diabetic retinopathy (DR) using Spectralis (Heidelberg Engineering, Heidelberg, Germany) wide-field optical coherence tomography (OCT). Methods: Retinal layers were segmented using a custom designed semi-automated algorithm, where reference points were marked by the examiner to enable software to automatically compute the thickness values of each retinal sublayer at an interval of 1 mm from reference points. The ...
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    5. Intraretinal, sub-retinal, and sub-retinal pigmented epithelium fluid in non-exudative age-related macular degeneration: follow-up with OCT imaging

      Intraretinal, sub-retinal, and sub-retinal pigmented epithelium fluid in non-exudative age-related macular degeneration: follow-up with OCT imaging
      Background/objectives: To evaluate the presence and evolution of fluid in non-exudative age-related macular degeneration (AMD) through serial OCT. Subjects/methods: A retrospective analysis of eyes with non-exudative AMD with a minimum of 4 year follow-up was done. Parameters including intraretinal fluid (IRF), subretinal fluid (SRF), and sub-retinal pigment epithelium (RPE) fluid (SRPEF); subfoveal choroidal thickness (SFCT) and type of drusen were evaluated using optical coherence tomography (OCT) scans at ...
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    6. Novel non-Invasive Biomarkers of Prodromal Alzheimer's Disease: the Role of Optical Coherence Tomography (OCT) and OCT-Angiography (OCT-A)

      Novel non-Invasive Biomarkers of Prodromal Alzheimer's Disease: the Role of Optical Coherence Tomography (OCT) and OCT-Angiography (OCT-A)
      Background: A reduction of retinal thickness and an alteration of retinal perfusion have been found in Alzheimer's disease (AD). Nowadays retinal layers and retinal perfusion can be evaluated by means of non-invasive imaging techniques, i.e., Optical Coherence Tomography (OCT) and OCT-Angiography (OCT-A). Here, we have compared the retinal thickness and the perfusion index, measured by means of OCT and OCT-A, in patients with mild cognitive impairment due to ...
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    7. Optical Coherence Tomography Angiography in Intermediate and Late Age-Related Macular Degeneration: Review of Current Technical Aspects and Applications

      Optical Coherence Tomography Angiography in Intermediate and Late Age-Related Macular Degeneration: Review of Current Technical Aspects and Applications
      Optical coherence tomography angiography (OCTA) is a non-invasive diagnostic instrument that has become indispensable for the management of age-related macular degeneration (AMD). OCTA allows quickly visualizing retinal and choroidal microvasculature, and in the last years, its use has increased in clinical practice as well as for research into the pathophysiology of AMD. This review provides a discussion of new technology and application of OCTA in intermediate and late AMD.
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    8. Swept source-OCT and swept source-OCT angiography findings in posterior microphthalmos

      Swept source-OCT and swept source-OCT angiography findings in posterior microphthalmos
      Purpose To describe swept source-OCT (SS-OCT) and swept source-OCT angiography (SS-OCTA) findings in eyes with posterior microphthalmos (PM). Methods Twelve eyes (six patients) with PM were evaluated using SS-OCT and SS-OCTA. Structural changes, subfoveal choroidal thickness (SFCT), and perifoveal capillary changes with qualitative and quantitative assessments were analyzed. Twenty eyes served as control group. Results SS-OCT findings included elevated retinal papillo-macular fold (75%), retinal pigment epithelium folds (83%), macular cystoid ...
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    9. Filigree vascular pattern in Combined Hamartoma of Retina and Retinal Pigment Epithelium on Optical Coherence Tomography Angiography

      Filigree vascular pattern in Combined Hamartoma of Retina and Retinal Pigment Epithelium on Optical Coherence Tomography Angiography
      Objective To evaluate the vascular structure within combined hamartoma of retina and retinal pigment epithelium (CHRRPE) lesions using optical coherence tomography angiography (OCT-A). Design: Multicentre retrospective observational analysis Subjects: 20 eyes of patients diagnosed with CHRRPE Methods Retrospective analysis of color fundus photographs, optical coherence tomography (OCT) and OCT-A of 20 eyes with CHRRPE. Morphological characteristics of CHRRPE and the OCT features were correlated with the density of the filigree ...
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    10. Comparative analysis of autofluorescence and OCT angiography in Stargardt disease

      Comparative analysis of autofluorescence and OCT angiography in Stargardt disease
      Aims To characterise the vasculature of the retina in patients with Stargardt disease (STGD) using optical coherence tomography angiography (OCTA) and to compare these functional findings with fundus autofluorescence (FAF) imaging. Methods This observational study included consecutive patients with STGD. The choriocapillaris (CC) layer was analysed on OCTA and retinal pigment epithelium (RPE) changes were assessed on FAF. Areas of CC and RPE impairment were quantified and correlated. Results Twenty-two ...
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    11. Optical coherence tomography angiography in age-related macular degeneration: The game changer

      Optical coherence tomography angiography in age-related macular degeneration: The game changer
      Optical coherence tomography angiography is one of the biggest advances in ophthalmic imaging. It enables a depth-resolved assessment of the retinal and choroidal blood flow, far exceeding the levels of detail commonly obtained with dye angiographies. One of the first applications of optical coherence tomography angiography was in detecting the presence of choroidal neovascularization in age-related macular degeneration and establishing its position in relation to the retinal pigmented epithelium and ...
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    12. Retinal Microvasculature in Nonproliferative Diabetic Retinopathy: Automated Quantitative Optical Coherence Tomography Angiography Assessment

      Retinal Microvasculature in Nonproliferative Diabetic Retinopathy: Automated Quantitative Optical Coherence Tomography Angiography Assessment
      Purpose: To perform a qualitative and quantitative assessment of the foveal microvasculature in eyes with diabetic maculopathy using optical coherence tomography angiography (OCT-A). Methods: Retrospective case series of 48 eyes with diabetic maculopathy and 47 healthy eyes evaluated by Spectralis OCT-A. Perifoveal arcade disruptions, linear vascular dilations, microaneurysms, intraretinal microvascular abnormalities and flow-void areas were qualitatively analyzed on OCT angiograms both for the superficial (SCP) and deep (DCP) capillary plexuses ...
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    13. Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach

      Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach
      The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of ...
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    14. A case of unilateral circumscribed posterior keratoconus evaluated by three different imaging tools: optical coherence tomography, videokeratography, and Scheimpflug corneal tomography

      A case of unilateral circumscribed posterior keratoconus evaluated by three different imaging tools: optical coherence tomography, videokeratography, and Scheimpflug corneal tomography
      Posterior keratoconus is a rare corneal anomaly which is part of the ectatic corneal disorders. We report a clinical presentation of a unilateral posterior keratoconus in a 42-year-old man. At the time of presentation, corrected distance visual acuity (CDVA) was 20/20 with a correction of +2.50 +2.50 90 in the right eye and 20/40 with +1 +3.00 105 in the left eye. Slit lamp microscopy ...
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    15. Optical Coherence Tomography Angiography of a Choroidal Neovascularization in Adult Onset Foveomacular Vitelliform Dystrophy: Pearls and Pitfalls

      Optical Coherence Tomography Angiography of a Choroidal Neovascularization in Adult Onset Foveomacular Vitelliform Dystrophy: Pearls and Pitfalls
      Purpose : The purpose of this study was to determine the sensitivity and specificity of optical coherence tomography angiography (OCT-A) in detecting choroidal neovascularization (CNV)-complicating adult onset foveomacular vitelliform dystrophy (AOFVD) and to highlight the possible pitfalls related to the heterogeneous spectrum of acquired vitelliform maculopathies. Methods : Twenty-five eyes of 22 consecutive AOFVD patients with suspected CNV were enrolled. Conventional multimodal imaging findings, based on fluorescein angiography (FA), indocyanine green ...
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    16. Repeatability of Retinal Macular Thickness Measurements in Healthy Subjects and Diabetic Patients with Clinically Significant Macular Edema: Evaluation of the Follow-Up System of Spectralis Optical Coherence Tomography

      Repeatability of Retinal Macular Thickness Measurements in Healthy Subjects and Diabetic Patients with Clinically Significant Macular Edema: Evaluation of the Follow-Up System of Spectralis Optical Coherence Tomography
      ...ts with CSME. aDepartment of Ophthalmology, Eye Clinic, and bDepartment of Economics, Finance and Statistics, University of Perugia, Perugia, and cDepartment of Oto-Neuro-Ophthalmological Surgical Sciences, Eye Clinic, F...
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  2. About University of Perugia

    University of Perugia

    University of Perugia is a public-owned university based in Perugia, Italy. It was founded in 1308, as attested by the Bull issued by Pope Clement V certifying the birth of the Studium Generale. The official seal of the university portraits Saint Herculan , one of the saint patrons, and the rampant crowned griffin, which is the city symbol: they represent the ecclesiastical and civil powers, respectively, which gave rise to the university in the Middle Ages.