1. University of Pennsylvania

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    1. Mentioned In 82 Articles

    2. A prospective study to assess in vivo optical coherence tomography imaging for early detection of chemotherapy-induced oral mucositis

      A prospective study to assess in vivo optical coherence tomography imaging for early detection of chemotherapy-induced oral mucositis
      Background and Objective Oral mucositis (OM) is a common and severe complication of many cancer therapies. Currently, prediction and early detection are not possible and objective monitoring remains problematic. Goal of this prospective study is to assess non-invasive imaging using optical coherence tomography (OCT) for early detection and evaluation of chemotherapy-induced OM in 48 patients, 12 of whom developed clinical mucositis. Study Design/Materials and Methods In 48 patients receiving ...
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    3. Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Choroidal Thickness in Fellow Eyes of Patients with Acute Primary Angle-Closure Measured by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography
      ...Ophthalmology, Sun Yat-sen University, Zhongshan Ophthalmic Center, Guangzhou, China 2. ^2School of Medicine, University of Pennsylvania, Scheie Eye Institute, Philadelphia, PA, United States 3. ^3State Key Laboratory of...
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    4. Optical Coherence Tomography Evaluation in the Multicenter Uveitis Steroid Treatment (MUST) Trial

      Optical Coherence Tomography Evaluation in the Multicenter Uveitis Steroid Treatment (MUST) Trial
      Purpose : To describe the evaluation of optical coherence tomography (OCT) scans in the Muliticenter Uveitis Steroid Treatment (MUST) trial and report baseline OCT features of enrolled participants. Methods : Time-domain OCTs acquired by certified photographers using a standardized scan protocol were evaluated at a reading center. Accuracy of retinal thickness data was confirmed with quality evaluation, and caliper measurement of centerpoint thickness (CPT) was performed when retinal thickness data were unreliable ...
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    5. In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques

      In vivo assessment of retinal neuronal layers in multiple sclerosis with manual and automated optical coherence tomography segmentation techniques
      Macular optical coherence tomography (OCT) segmentation, enabling quantification of retinal axonal and neuronal subpopulations, may help elucidate the neuroretinal pathobiology of multiple sclerosis (MS). This study aimed to determine the agreement, reproducibility, and visual correlations of retinal layer thicknesses measured by different OCT segmentation techniques, on two spectral-domain OCT devices. Macular scans of 52 MS patients and 30 healthy controls from Spectralis OCT and Cirrus HD-OCT were segmented using fully ...
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    6. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ww.lehigh.edu/.   About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked with Professor Arjun G. Yodh on the development of diffuse optical...
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    7. Frontiers in optical imaging of cerebral blood flow and metabolism

      Frontiers in optical imaging of cerebral blood flow and metabolism
      In vivo optical imaging of cerebral blood flow (CBF) and metabolism did not exist 50 years ago. While point optical fluorescence and absorption measurements of cellular metabolism and hemoglobin concentrations had already been introduced by then, point blood flow measurements appeared only 40 years ago. The advent of digital cameras has significantly advanced two-dimensional optical imaging of neuronal, metabolic, vascular, and hemodynamic signals. More recently, advanced laser sources have enabled ...
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    8. Vision in Multiple Sclerosis: The Story, Structure-Function Correlations, and Models for Neuroprotection

      Vision in Multiple Sclerosis: The Story, Structure-Function Correlations, and Models for Neuroprotection
      Abstract: Visual dysfunction is one of the most common clinical manifestations of multiple sclerosis (MS). Just over a decade ago, MS clincial trials did not include visual outcomes, but experts recognized the need for more sensitive measures of visual function. Low-contrast letter acuity emerged as the leading candidate to measure visual disability in MS, and subsequent studies found low-contrast acuity testing to correlate well with brain MRI lesion burden, visual-evoked ...
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    9. Two Graduate Research Assistant Positions in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Two Graduate Research Assistant Positions in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...ww.lehigh.edu/.   About Dr. Chao Zhou: Dr. Chao Zhou obtained his Ph.D. degree in physics in 2007 from the University of Pennsylvania, where he worked with Professor Arjun G. Yodh on the development of diffuse optical...
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    10. The Impact of Utilizing Different Optical Coherence Tomography Devices for Clinical Purposes and in Multiple Sclerosis Trials

      The Impact of Utilizing Different Optical Coherence Tomography Devices for Clinical Purposes and in Multiple Sclerosis Trials
      ...ity of Texas Southwestern Medical Center, Dallas, Texas, United States of America, 4 Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America Optical co...
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    11. MIT Receives NIH Award for Integrated Optical Coherence Tomography and Microscopy for Molecular-Targeted Imaging

      MIT Receives NIH Award for Integrated Optical Coherence Tomography and Microscopy for Molecular-Targeted Imaging
      ...ies conducted by the candidate. The candidate, Dr. Chao Zhou, completed rigorous training in physics from the University of Pennsylvania and is continuing his postdoctoral research at the Massachusetts Institute of Techn...
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    12. Retinal Ganglion Cell Layer Volumetric Assessment by Spectral-Domain Optical Coherence Tomography in Multiple Sclerosis: Application of a High-Precision Manual Estimation Technique

      Retinal Ganglion Cell Layer Volumetric Assessment by Spectral-Domain Optical Coherence Tomography in Multiple Sclerosis: Application of a High-Precision Manual Estimation Technique
      Background: Neuronal loss in the retina has been demonstrated pathologically in eyes of patients with multiple sclerosis (MS). In vivo, MS eyes have reduced total macular volumes by optical coherence tomography (OCT). Using a high-resolution spectral-domain OCT, this pilot study used a manual method to measure ganglion cell layer (GCL) volumes and to determine the relation of these volumes to visual function in MS eyes. Methods: Sixteen eyes of 8 ...
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    13. 46-60 of 82 « 1 2 3 4 5 6 »
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  2. About University of Pennsylvania

    University of Pennsylvania

    University of Pennsylvania (commonly referred to as Penn or UPenn), one of the eight members of the Ivy League, is a private research university located in Philadelphia, Pennsylvania, United States. Penn is the fourth-oldest institution of higher education in the United States, and is considered the first university in the United States, with both undergraduate and graduate studies. Penn is also one of the Colonial Colleges.