1. University of Oulu

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    1. Mentioned In 69 Articles

    2. Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure

      Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure
      Conventional arthroscopic evaluation of articular cartilage is subjective and poorly reproducible. Therefore, implementation of quantitative diagnostic techniques, such as near infrared spectroscopy (NIRS) and optical coherence tomography (OCT), is essential. Locations ( n =44) with various cartilage conditions were selected from mature equine fetlock joints ( n =5). These locations and their surroundings were measured with NIRS and OCT ( n =530). As a reference, cartilage proteoglycan (PG) and collagen contents, and collagen ...
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    3. Noninvasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

      Noninvasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles
      The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive ...
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    4. Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound

      Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound
      Background and purpose Arthroscopic estimation of articular cartilage thickness is important for scoring of lesion severity, and measurement of cartilage speed of sound (SOS)a sensitive index of changes in cartilage composition. We investigated the accuracy of optical coherence tomography (OCT) in measurements of cartilage thickness and determined SOS by combining OCT thickness and ultrasound (US) time-of-flight (TOF) measurements. Material and methods Cartilage thickness measurements from OCT and microscopy images ...
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    5. BIOPHOTONICS AND IMAGING SUMMER SCHOOL (BIGSS 2016)

      BIOPHOTONICS AND IMAGING SUMMER SCHOOL (BIGSS 2016)
      The Bi-annual Biophotonics and Imaging Summer School (BIGSS16) will be held 5-9 September 2016 in Galway, Ireland. It is a five ECTS accredited course with leading professors teaching. Sessions are approx. four hours each to give a substantial grounding in the main topics of Biophotonics. The location is in the picturesque village of Ballyvaughanin the Burren . This will be augmented with hands on training at NUI Galway. Fee: 800 including ...
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    6. Quantification of cell-free layer thickness and cell distribution of blood by optical coherence tomography

      Quantification of cell-free layer thickness and cell distribution of blood by optical coherence tomography
      A high-speed optical coherence tomography (OCT) with 1 - m axial resolution was applied to assess the thickness of a cell-free layer (CFL) and a spatial distribution of red blood cells (RBC) next to the microchannel wall. The experiments were performed in vitro in a plain glass microchannel with a width of 2 mm and height of 0.2 mm. RBCs were suspended in phosphate buffered saline solution at the hematocrit ...
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    7. Optical clearing of articular cartilage: a comparison of clearing agents

      Optical clearing of articular cartilage: a comparison of clearing agents
      Optical clearing technique was applied to the problem of OCT imaging of articular cartilage and subchondral bone. We show that optical clearing significantly enhances visualization of articular cartilage and cartilage-bone interface. The effect of different clearing agents was analyzed. For the clearing, iohexol solution and propylene glycol (PG) were used. Clearing was performed in vitro at room temperature by immersion method. Cylindrical osteochondral samples (d=4.8mm) were drilled from ...
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    8. Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage

      Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage
      Optical clearing is an effective method to reduce light scattering of biological tissues that provides significant enhancement of light penetration into the biological tissues making non-invasive diagnosis more feasible. In current report Optical Coherence Tomography (OCT) in conjunction with optical clearing is applied for assessment of deep cartilage layers and cartilage-bone interface. The solution of Iohexol in water has been used as an optical clearing agent. The cartilage-bone boundary becomes ...
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    9. Evaluation of Freshness of Soft Tissue Samples with Optical Coherence Tomography Assisted by Low Frequency Electric Field

      Evaluation of Freshness of Soft Tissue Samples with Optical Coherence Tomography Assisted by Low Frequency Electric Field
      We present an optical coherence tomography based methodology to determine freshness of soft tissue samples by evaluation of their interaction with low frequency electric field. Various biological tissues samples of different stages of freshness were exposed by low frequency electric current. The influence of the low frequency electric field on tissues was observed and quantified by the double correlation optical coherence tomography (dcOCT) approach developed in house. The quantitative evaluation ...
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    10. Gold nanostructures for OCT imaging of capillary flow

      Gold nanostructures for OCT imaging of capillary flow
      In this paper, plasmon-resonant nanostructures, such as gold nanostars and their silica-coated composites, were used for enhancement of OCT image contrast of water flows in glass capillaries. The contrasting properties of the synthesized nanostars and nanocomposites with silica shell thickness of about 5 nm and 50 nm were compared in the framework of capillary stasis model. The most intensive signal was detected from the nanocomposites with the thickest silica shell ...
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    11. Optical Coherence Tomography as a Characterization Method in Printed Electronics (Thesis)

      Optical Coherence Tomography as a Characterization Method in Printed Electronics (Thesis)
      This Thesis proposes and describes the use of optical coherence tomography (OCT) as a non-contact and non-destructive characterization technique for printed electronics. It is based on and includes the first published results of such an application of the OCT technique. Several different types of structures were studied to evaluate the feasibility of the application. The measurement data was used to define the surface topography, physical dimensions of the specimen features ...
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    12. Handbook of Coherent-Domain Optical Methods - Second Addition (Book)

      Handbook of Coherent-Domain Optical Methods - Second Addition (Book)
      This handbook deals with laser and coherent-domain methods as applied to biomedical diagnostics, environmental monitoring, and materials inspection. It is a second edition of the two-volume Handbook of Coherent-Domain Optical Methods for Biomedical Diagnostics, Environmental and Material Science published by Kluwer Academic Publishers in 2004. The appearance of this book was stimulated by the recent rapid progress in novel photonics technologies on the basis of diode lasers, broadband femtosecond lasers ...
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  2. About University of Oulu

    University of Oulu

    University of Oulu is an international scientific community known for high-quality research and education that provides experts for demanding tasks on both national and international level. The University promotes well-being and education in Northern Finland and is a significant player in the Finnish and European re-search based system of innovation and education.

    Optoelectronics and Measurement Techniques Laboratory at the University of Oulu, Finland.  Optoelectronics and measurement tehniques laboratory is specialized in demanding electronic applications. The laboratory is a member in Infotech Oulu.  Laboratory has a long history of measuring human vitalities. Presently it focuses on optical, non-invasive blood glucose measurements. Main scattering materials under research are pulp and paper. The newest major equipment purchase, a femtosecond laser, is for this kind of optical material research.