1. University of North Carolina

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    1. Mentioned In 115 Articles

    2. Esophageal OCT Imaging Using a Paddle Probe Externally Attached to Endoscope

      Esophageal OCT Imaging Using a Paddle Probe Externally Attached to Endoscope
      Background and aims: Endoscopic surveillance of Barrett's esophagus (BE) by white light examination is insufficient to diagnose dysplastic change. In this work, we describe an optical imaging method to obtain high-resolution cross-sectional imaging using a paddle-shaped probe affixed to the endoscope tip. Methods: We integrated Optical Coherence Tomography (OCT), an optical imaging method that produces cross-sectional images, into a paddle probe attached to video endoscope. We acquired images of ...
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    3. Anatomic Optical Coherence Tomography (aOCT) for Evaluation of the Internal Nasal Valve

      Anatomic Optical Coherence Tomography (aOCT) for Evaluation of the Internal Nasal Valve
      Objectives/hypothesis: To establish the utility of anatomic optical coherence tomography (aOCT) in evaluating internal nasal valve (INV). Study design: Anatomic specimen imaging study. Methods: Fresh-harvested human specimen heads were evaluated using both computed tomography (CT) imaging as well as using aOCT. Scans were performed at three time points: 1) After septoplasty for cartilage harvest, 2) after placement of butterfly graft (BFG), and 3) after placement of bilateral spreader grafts ...
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    4. Connectivity-based deep learning approach for segmentation of the epithelium in in vivo human esophageal OCT images

      Connectivity-based deep learning approach for segmentation of the epithelium in in vivo human esophageal OCT images
      Optical coherence tomography (OCT) is used for diagnosis of esophageal diseases such as Barrett's esophagus. Given the large volume of OCT data acquired, automated analysis is needed. Here we propose a bilateral connectivity-based neural network for in vivo human esophageal OCT layer segmentation. Our method, connectivity-based CE-Net (Bicon-CE), defines layer segmentation as a combination of pixel connectivity modeling and pixel-wise tissue classification. Bicon-CE outperformed other widely used neural networks ...
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    5. Role of Optical Coherence Tomography Angiography Imaging in Patients with Diabetes

      Role of Optical Coherence Tomography Angiography Imaging in Patients with Diabetes
      Purpose of Review Ocular manifestations in patients with diabetes mellitus (DM) can present as microvascular changes. These microvascular changes can be challenging to identify on exams, and imaging technologies have commonly aided in the diagnosis and management of patients with DM. Optical coherence tomography angiography (OCTA) provides noninvasive image segmentation of various layers of the retina and choroid. Also, post-processing of images and associated quantitative measurements offer potential clinical enhancements ...
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    6. OCT particle tracking velocimetry of biofluids in a microparallel plate strain induction chamber

      OCT particle tracking velocimetry of biofluids in a microparallel plate strain induction chamber
      Significance: Imaging biofluid flow under physiologic conditions aids in understanding disease processes and health complications. We present a method employing a microparallel plate strain induction chamber (MPPSIC) amenable to optical coherence tomography to track depth-resolved lateral displacement in fluids in real time while under constant and sinusoidal shear. Aim: Our objective is to track biofluid motion under shearing conditions found in the respiratory epithelium, first validating methods in Newtonian fluids ...
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    7. University of North Carolina Receives NIH Grant for Predicting the Need for Surgery in Pediatric Subglottic Stenosis using Airway Elastography Derived from Endoscopic OCT and Intraluminal Pressure Measurement

      University of North Carolina Receives NIH Grant for Predicting the Need for Surgery in Pediatric Subglottic Stenosis using Airway Elastography Derived from Endoscopic OCT and Intraluminal Pressure Measurement
      ... as obstructive sleep apnea (~10% of the population), in children and adults.

      University of North Carolina Receives a 2021 NIH Grant for $797,092 for Predicting the Need for Surgery in Ped...

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    8. All-fiber probes for endoscopic optical coherence tomography of the large airways

      All-fiber probes for endoscopic optical coherence tomography of the large airways
      Endoscopic optical coherence tomography of large airways poses unique challenges. A hybrid lens is described that consists of a section of coreless fiber and graded index fiber (GIF), followed by a ball lens section. This design produces low numerical aperture beams better suited for large airway imaging. The performance of this lens is compared against conventional GIF and ball lens designs. Forward- and side-viewing probes were modeled, fabricated, and tested ...
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    9. Atlas of Optical Coherence Tomography for Glaucoma (Textbook)

      Atlas of Optical Coherence Tomography for Glaucoma (Textbook)
      Atlas of Optical Coherence Tomography for Glaucoma is a case-based atlas intended to teach the reader how to interpret the results of OCT in glaucoma patients and glaucoma suspects. After a brief description of how OCT is used in particular situations, chapters depict actual case presentations from authors practices with legends that describe the case and how OCT is used to make the diagnosis of glaucoma or glaucoma progression. Emphasis ...
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    10. DEVELOPMENT OF A LINE-FIELD MAGNETO-MOTIVE OPTICAL COHERENCE TOMOGRAPHY SYSTEM (Thesis)

      DEVELOPMENT OF A LINE-FIELD MAGNETO-MOTIVE OPTICAL COHERENCE TOMOGRAPHY SYSTEM (Thesis)
      The mechanism by which certain species of animals are able to detect the Earths magnetic field has remained a mystery for as long as we have known that they exhibit geomagnetic navigation. Certain species of bacteria are known to contain single chains of magnetite crystals, each with a diameter of ~50 nm, that are used to orient the bacteria. Searching for similar magnetoreceptors in larger animals requires a high-speed, high-resolution ...
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    11. Tracking the invasion of breast cancer cells in paper-based 3D cultures by OCT motility analysis

      Tracking the invasion of breast cancer cells in paper-based 3D cultures by OCT motility analysis
      3D paper-based cultures (PBCs) are easy-to-use and provide a biologically representative microenvironment. By stacking a sheet of cell-laden paper below sheets containing cell-free hydrogel, we form an assay capable of segmenting cells by the distance they invaded from the original cell-seeded layer. These invasion assays are limited to end-point analyses with fluorescence-based readouts due to the highly scattering nature of the paper scaffolds. Here we demonstrate that optical coherence tomography ...
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    12. a/LCI-OCT Pilot in Esophagus

      a/LCI-OCT Pilot in Esophagus
      This study will test a newly developed dual modality probe, including optical coherence tomography (OCT) and angle-resolved low-coherence interferometry (a/LCI), in the human esophagus to determine 1) whether adequate tissue contact can be attained by the probe to acquire high quality images, and 2) to identify if these images can discern whether the imaged tissue is squamous or Barrett's Esophagus (BE) epithelium. This pilot study will test the ...
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    13. 1-15 of 115 1 2 3 4 5 6 7 8 »
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  2. About University of North Carolina

    University of North Carolina

    University of North Carolina was chartered in 1789, and was the first public university in the United States and the only one to graduate students in the eighteenth century. Today, UNC is a multi-campus university composed of all 16 of North Carolina's public institutions that grant baccalaureate degrees, as well as the NC School of Science and Mathematics, the nation's first public residential high school for gifted students.