1. University of Montreal

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    1. Mentioned In 22 Articles

    2. Open-source algorithm for automatic choroid segmentation of OCT volume reconstructions

      Open-source algorithm for automatic choroid segmentation of OCT volume reconstructions
      The use of optical coherence tomography (OCT) to study ocular diseases associated with choroidal physiology is sharply limited by the lack of available automated segmentation tools. Current research largely relies on hand-traced, single B-Scan segmentations because commercially available programs require high quality images, and the existing implementations are closed, scarce and not freely available. We developed and implemented a robust algorithm for segmenting and quantifying the choroidal layer from 3-dimensional ...
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    3. Cystoid macular changes on optical coherence tomography in a patient with maternally inherited diabetes and deafness (MIDD)-associated macular dystrophy

      Cystoid macular changes on optical coherence tomography in a patient with maternally inherited diabetes and deafness (MIDD)-associated macular dystrophy
      The clinical presentation and optical coherence tomography findings in a patient with maternally inherited diabetes and deafness (MIDD) are presented to highlight the presence of macular cystoid spaces in some patients with this disease. Typically, patients with MIDD demonstrate progression of a pigmentary maculopathy into areas of geographic macular atrophy. At the time of initial visit, the 30-year-old patient had large macular cystoid changes in addition to retinal pigmentary changes ...
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    4. Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents

      Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents
      Purpose : Spectral-domain optical coherence tomography (SD-OCT) is widely used in clinical ophthalmology and recently gained popularity in laboratory research involving small rodents. Its noninvasive nature allows repeated measurements, thereby decreasing the number of animals required. However, when used at a conventional dosage, xylazine (an 2-adrenoceptor) can cause irreversible corneal calcification, especially among young rodents. In the present study, we test whether corneal calcification associated with xylazine is mediated by the ...
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    5. Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome

      Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing’s Syndrome
      Context: Cortisol has been suggested as a risk factor for choroidal thickening, which may lead to retinal changes. Objective: To compare choroidal thickness measurements using optical coherence tomography (OCT) in patients with endogenous active Cushings syndrome (CS) and to evaluate the occurrence of retinal abnormalities in the same group of patients. Design: Cross-sectional study. Setting: Outpatient clinic. Patients: Eleven female patients with CS in hypercortisolism state as determined by the ...
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    6. Validating Intravascular Imaging with Serial Optical Coherence Tomography and Confocal Fluorescence Microscopy

      Validating Intravascular Imaging with Serial Optical Coherence Tomography and Confocal Fluorescence Microscopy
      Atherosclerotic cardiovascular diseases are characterized by the formation of a plaque in the arterial wall. Intravascular ultrasound (IVUS) provides high-resolution images allowing delineation of atherosclerotic plaques. When combined with near infrared fluorescence (NIRF), the plaque can also be studied at a molecular level with a large variety of biomarkers. In this work, we present a system enabling automated volumetric histology imaging of excised aortas that can spatially correlate results with ...
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    7. Tri-modal microscope for head and neck tissue identification

      Tri-modal microscope for head and neck tissue identification
      A novel tri-modal microscope combining optical coherence tomography (OCT), spectrally encoded confocal microscopy (SECM) and fluorescence imaging is presented. This system aims at providing a tool for rapid identification of head and neck tissues during thyroid surgery. The development of a dual-wavelength polygon-based swept laser allows for synchronized, co-registered and simultaneous imaging with all three modalities. Further ameliorations towards miniaturization include a custom lens for optimal compromise between orthogonal imaging ...
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    8. Very, very late stent thrombosis triggered by in-stent neoatherosclerosis: optical coherence tomography findings

      Very, very late stent thrombosis triggered by in-stent neoatherosclerosis: optical coherence tomography findings
      A 64-year-old woman with dyslipidemia, hypertension and type 2 diabetes plus an existing 4.0-mm 28-mm bare-metal stent (BMS; Multilink Penta, Abbott Vascular, US) deployed over 10 years ago in the right coronary artery (RCA) was admitted to our emergency department with inferolateral and posterior ST-segment elevation acute myocardial infarction. Coronary angiography showed occlusion and thrombotic plaque in the mid RCA at the site of the prior stent implantation. After ...
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    9. Automatic segmentation of the optic nerve head for deformation measurements in video rate optical coherence tomography

      Automatic segmentation of the optic nerve head for deformation measurements in video rate optical coherence tomography
      Optical coherence tomography (OCT) imaging has become a standard diagnostic tool in ophthalmology, providing essential information associated with various eye diseases. In order to investigate the dynamics of the ocular fundus, we present a simple and accurate automated algorithm to segment the inner limiting membrane in video-rate optic nerve head spectral domain (SD) OCT images. The method is based on morphological operations including a two-step contrast enhancement technique, proving to ...
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    10. Anterior Segment Optical Coherence Tomography in the Long-Term Follow-up and Detection of Glaucoma in Boston Type I Keratoprosthesis

      Anterior Segment Optical Coherence Tomography in the Long-Term Follow-up and Detection of Glaucoma in Boston Type I Keratoprosthesis
      ...gher x Mona Harissi-Dagher Search for articles by this author Affiliations * Department of Ophthalmology, Université de Montréal, Québec, Canada Correspondence * Correspondence: Mona Harissi-Dagher, MD, Hôpital N...
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    11. Architectural Analysis of Clear Corneal Incision Techniques in Cataract Surgery Using Fourier-Domain OCT

      Architectural Analysis of Clear Corneal Incision Techniques in Cataract Surgery Using Fourier-Domain OCT
      BACKGROUND AND OBJECTIVE: To compare the architecture of single plane self-sealing clear corneal incision (SP-CCI) and shallow grooved self-sealing clear corneal incision (SG-CCI) after cataract surgery using Fourier-domain optical coherence tomography (FD-OCT). PATIENTS AND METHODS: An FD-OCT system with a corneal adaptor module was used to image the corneal incisions in radial sections in 44 eyes. A line scan pattern was used to measure the corneal incision, positioning the caliper ...
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    12. Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

      Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow
      Endothelial dysfunction and oxidative stress contribute to the atherosclerotic process that includes stiffening of large peripheral arteries. In contrast, we previously reported a paradoxical increase in cerebrovascular compliance in LDLr-/-: hApoB+/+ atherosclerotic (ATX) mice. We hypothesized that prevention of cerebral artery endothelial function with a chronic dietary antioxidant intake would normalize the changes in cerebral artery wall structure and biomechanics and prevent the decline in basal cerebral blood flow (CBF ...
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    13. Spectral optical coherence tomography in a patient with type I sialidosis

      Spectral optical coherence tomography in a patient with type I sialidosis
      Background: The aim of our study was to analyze spectral optical coherence tomography (SD-OCT) findings in a patient with clinical signs of sialidosis. Case Report: Fluorescein angiography and spectral optical coherence tomography was performed in a 37-year-old woman using a SD-OCT device with axial resolution of 6 µm. Enzyme assay followed. The patient was diagnosed with type I sialidosis by enzymatic assay. Besides a normal angiogram, a thickened nerve fiber ...
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    14. 1-15 of 22 1 2 »
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  2. About University of Montreal

    University of Montreal

    University of Montreal, with its two affiliated schools, the École Polytechnique and the HEC Montréal, is now the largest university in Quebec and the second largest in Canada. With over 55,000 students from around the world and some 10,000 employees, the Université de Montréal awards close to 10,000 diplomas at every university level.   Maisonneuve Rosemont Hospital is a large institution where Montreal converge care, education and medical research. Its 5,000 employees and physicians working in a warm living environment and to meet the needs of the population in eastern Montreal and even beyond. Affiliated with the University of Montreal, HMR is also a place of learning and innovation in education and medical research. It receives each year more than 3000 students, future doctors, nurses and health professionals who will work for tomorrow. Many scientific and medical research are also conducted to develop new treatments and cures, giving hope to people suffering from currently incurable diseases.