1. University of Montreal

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    1. Mentioned In 35 Articles

    2. The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases

      The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases
      Background: This study reports on the advantages of wide-field (WF)- and ultra-widefield (UWF)- optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in managing different vitreoretinal diseases in a real-life setting using the new WF-Swept Source (SS)-OCT Xephilio S1 (Canon, Tokyo, Japan). Methods: We conducted an observational retrospective case series study involving 1472 eyes that underwent retinal scans with Canon Xephilio OCT-S1 between 1 March 2021 and 1 ...
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    3. Development and ex-vivo validation of 36G polyimide cannulas integrating a guiding miniaturized OCT probe for robotic assisted subretinal injections

      Development and ex-vivo validation of 36G polyimide cannulas integrating a guiding miniaturized OCT probe for robotic assisted subretinal injections
      We introduced and validated a method to encase guiding optical coherence tomography (OCT) probes into clinically relevant 36G polyimide subretinal injection (SI) cannulas. Modified SI cannulas presented consistent flow capacity and tolerated the typical mechanical stress encountered in clinical use without significant loss of sensitivity. We also developed an approach that uses a micromanipulator, modified SI cannulas, and an intuitive graphical user interface to enable precise SI. We tested the ...
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    4. Bilateral diffuse uveal melanocytic proliferation: Report of a novel optical coherence tomography finding and clinical response to plasmapheresis

      Bilateral diffuse uveal melanocytic proliferation: Report of a novel optical coherence tomography finding and clinical response to plasmapheresis
      Purpose: To describe a novel optical coherence tomography (OCT) finding in a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) and to report the clinical response to plasmapheresis. Observations: We report the case of a 54-year-old man who was being treated with adjuvant immune checkpoint inhibitors for metastatic renal cell carcinoma. He had suffered from bilateral progressive vision loss without ocular pain. At presentation in the retina clinic, visual acuity ...
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    5. Paracentral acute middle maculopathy in non-ischaemic central retinal vein occlusion: the role of en face optical coherence tomography

      Paracentral acute middle maculopathy in non-ischaemic central retinal vein occlusion: the role of en face optical coherence tomography
      A 64-year-old man presented with an acute-onset central visual deficit in the left eye. He described a specific pattern of paracentral scotoma consisting of grey spots arranged in a honeycomb pattern. He was a 10 pack-year smoker and his medications included low-dose aspirin, which was prescribed, 2years prior, following an episode of amaurosis fugax in the same eye. Investigations at that time had not revealed significant carotid stenosis. He was ...
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    6. Morphometric and Microstructural Changes During Murine Retinal Development Characterized Using In Vivo Optical Coherence Tomography

      Morphometric and Microstructural Changes During Murine Retinal Development Characterized Using In Vivo Optical Coherence Tomography
      Purpose : The purpose of this study was to develop an in vivo optical coherence tomography (OCT) system capable of imaging the developing mouse retina and its associated morphometric and microstructural changes. Methods : Thirty-four wild-type mice (129S1/SvlmJ) were anesthetized and imaged between postnatal (P) day 7 and P21. OCT instrumentation was developed to optimize signal intensity and image quality. Semi-automatic segmentation tools were developed to quantify the retinal thickness of ...
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    7. Longitudinal optical coherence tomography imaging of tissue repair and microvasculature regeneration and function after targeted cerebral ischemia

      Longitudinal optical coherence tomography imaging of tissue repair and microvasculature regeneration and function after targeted cerebral ischemia
      Significance: Understanding how the brain recovers from cerebral tissue and vascular damage after an ischemic event can help develop new therapeutic strategies for the treatment of stroke. Aim: We investigated cerebral tissue repair and microvasculature regeneration and function after a targeted ischemic stroke. Approach: Following photothrombosis occlusion of microvasculature, chronic optical coherence tomography (OCT)-based angiography was used to track ischemic tissue repair and microvasculature regeneration at three different cortical ...
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    8. Predicting the risk for angle closure as defined by the Shaffer System Using Anterior Segment Optical Coherence Tomography: A Simple Approach

      Predicting the risk for angle closure as defined by the Shaffer System Using Anterior Segment Optical Coherence Tomography: A Simple Approach
      Purpose: To propose a simple non-invasive method for screening patients at risk for angle closure using anterior segment OCT. Methods: Scans of nasal and temporal iridocorneal angles in glaucoma suspect patients were performed using OCT. Upon identifying Schwalbes line, the integrated caliper tool was used to draw a line to the nearest point of the iris to produce a measure S-I. Gonioscopy was performed and angles graded according to Shaffers ...
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    9. Etching-enabled extreme miniaturization of graded-index fiber-based optical coherence tomography probes

      Etching-enabled extreme miniaturization of graded-index fiber-based optical coherence tomography probes
      We introduced and validated a method to miniaturize graded-index (GRIN) fiber-based optical coherence tomography (OCT) probes down to 70m in diameter. The probes consist in an assembly of single-mode (SM), coreless (CL), and graded-index (GRIN) fibers. We opted for a probe design enabling controlled size reduction by hydrogen fluoride etching. The fabrication approach prevents nonuniform etching for both the GRIN and SM fiber components, while it requires no probe polishing ...
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    10. Fully automated dual-resolution serial optical coherence tomography aimed at diffusion MRI validation in whole mouse brains

      Fully automated dual-resolution serial optical coherence tomography aimed at diffusion MRI validation in whole mouse brains
      An automated dual-resolution serial optical coherence tomography (2R-SOCT) scanner is developed. The serial histology system combines a low-resolution (25m/voxel) 3 OCT with a high-resolution (1.5m/voxel) 40 OCT to acquire whole mouse brains at low resolution and to target specific regions of interest (ROIs) at high resolution. The 40 ROIs positions are selected either manually by the microscope operator or using an automated ROI positioning selection algorithm. Additionally ...
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    11. Open-source algorithm for automatic choroid segmentation of OCT volume reconstructions

      Open-source algorithm for automatic choroid segmentation of OCT volume reconstructions
      The use of optical coherence tomography (OCT) to study ocular diseases associated with choroidal physiology is sharply limited by the lack of available automated segmentation tools. Current research largely relies on hand-traced, single B-Scan segmentations because commercially available programs require high quality images, and the existing implementations are closed, scarce and not freely available. We developed and implemented a robust algorithm for segmenting and quantifying the choroidal layer from 3-dimensional ...
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    12. Cystoid macular changes on optical coherence tomography in a patient with maternally inherited diabetes and deafness (MIDD)-associated macular dystrophy

      Cystoid macular changes on optical coherence tomography in a patient with maternally inherited diabetes and deafness (MIDD)-associated macular dystrophy
      The clinical presentation and optical coherence tomography findings in a patient with maternally inherited diabetes and deafness (MIDD) are presented to highlight the presence of macular cystoid spaces in some patients with this disease. Typically, patients with MIDD demonstrate progression of a pigmentary maculopathy into areas of geographic macular atrophy. At the time of initial visit, the 30-year-old patient had large macular cystoid changes in addition to retinal pigmentary changes ...
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    13. 1-15 of 35 1 2 3 »
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  2. About University of Montreal

    University of Montreal

    University of Montreal, with its two affiliated schools, the École Polytechnique and the HEC Montréal, is now the largest university in Quebec and the second largest in Canada. With over 55,000 students from around the world and some 10,000 employees, the Université de Montréal awards close to 10,000 diplomas at every university level.   Maisonneuve Rosemont Hospital is a large institution where Montreal converge care, education and medical research. Its 5,000 employees and physicians working in a warm living environment and to meet the needs of the population in eastern Montreal and even beyond. Affiliated with the University of Montreal, HMR is also a place of learning and innovation in education and medical research. It receives each year more than 3000 students, future doctors, nurses and health professionals who will work for tomorrow. Many scientific and medical research are also conducted to develop new treatments and cures, giving hope to people suffering from currently incurable diseases.