1. University of Missouri

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    1. Mentioned In 21 Articles

    2. Optical tractography of the mouse heart using polarization-sensitive optical coherence tomography

      Optical tractography of the mouse heart using polarization-sensitive optical coherence tomography

      We developed a method to image myocardial fiber architecture in the mouse heart using a Jones matrix-based polarization-sensitive optical coherence tomography (PSOCT) system. The “cross-helical” laminar structure of myocardial fibers can be clearly visualized using this technology. The obtained myocardial fiber organization agrees well with existing knowledge acquired using conventional histology and diffusion tensor magnetic resonance imaging

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    3. Mapping local optical axis in birefringent samples using polarization-sensitive optical coherence tomography

      Mapping local optical axis in birefringent samples using polarization-sensitive optical coherence tomography

      An algorithm was developed to obtain depth-resolved local optical axis in birefringent samples by using conventional polarization-sensitive optical coherence tomography (PSOCT) that uses a single circularly polarized incident light. The round-trip sample Jones matrices were first constructed from the cumulative PSOCT results. An iterative method was then applied to construct the depth-resolved local Jones matrix from which the local optical axis was calculated. The proposed algorithm was validated in samples with homogeneous axis and with depth-varying optical axis. Imaging examples were shown to demonstrate the capability of this method for extracting correct local axis and revealing features not evident in ...

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    4. Full-range spectral domain Jones matrix optical coherence tomography using a single spectral camera

      Full-range spectral domain Jones matrix optical coherence tomography using a single spectral camera

      Jones matrix optical coherence tomography can fully characterize depth-resolved polarization properties in tissue. In this report, we described a simple single-camera based implementation of full-range spectral domain Jones matrix optical coherence tomography. The Jones matrix reconstruction algorithm was described in detail and system calibration was demonstrated with comprehensive examples. In addition to the conventional structural image, the images of retardance, optical axis and relative attenuation can be obtained from the measured Jones matrix image. Both in vitro and in vivo image examples were presented to demonstrate the polarization imaging ability of the system

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    5. 3D imaging of tomato seeds using frequency domain optical coherence tomography

      3D imaging of tomato seeds using frequency domain optical coherence tomography

      A fast imaging system that can reveal internal sample structures is important for research and quality controls of seeds. Optical coherence tomography (OCT) is a non-invasive optical imaging technique that can acquire high speed, high resolution depth-resolved images in scattering samples. It has found numerous applications in studying various biological tissues and other materials in vivo. A few studies have reported the use of OCT in studying seed morphology. However, 3D imaging of internal seed structure has not been reported before. In this study, we used a frequency domain OCT system to image tomato seeds. The system has a central ...

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    6. Mapping local retardance in birefringent samples using polarization sensitive optical coherence tomography

      Mapping local retardance in birefringent samples using polarization sensitive optical coherence tomography

      We proposed a method to extract depth-resolved local retardance in birefringent samples from conventional polarization-sensitive optical coherence tomography (PSOCT) that uses one circularly polarized incident light. Despite the wide use of such PSOCT systems in characterizing birefringent samples, the measured cumulative retardance does not represent the true cumulative retardance when optical axis varies with depth. A Jones calculus based algorithm was designed to derive the local depth-resolved retardance from conventional cumulative PSOCT results. The algorithm was tested in samples with homogeneous optical axis as well as samples with depth-dependent optical axis.

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    7. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ...,406   UNIVERSITY OF GEORGIA (UGA) $168,615 UPSTATE MEDICAL UNIVERSITY $2,161,575   UNIVERSITY OF MISSOURI-ST. LOUIS $165,526 CORNELL UNIVERSITY ITHACA $2,143,277   OPTICAL BI...
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    8. Spectral domain optical coherence tomography findings of acute branch retinal artery occlusion from calcific embolus

      Spectral domain optical coherence tomography findings of acute branch retinal artery occlusion from calcific embolus
      ...nd Vision Research Center at Truman Medical Center, Kansas City, MO, USA Correspondence Address: Vinay A Shah University of Missouri Kansas City, Department of Ophthalmology, 2300 Holmes Street, Kansas City, MO-641 08 US...
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    9. Correcting Optical-Axis Calculation in Polarization-Sensitive Optical Coherence Tomography

      Correcting Optical-Axis Calculation in Polarization-Sensitive Optical Coherence Tomography

      Polarization-sensitive optical coherence tomography (PSOCT) has found many applications in imaging birefringence tissue samples. Polarization-sensitive detection is often implemented by utilizing a circularly polarized incident light and detecting the two orthogonal horizontal- and vertical-polarized interference components. However, the obtained optical axes images were inappropriately represented as depth-dependent periodic maps in all reported studies. A detailed analysis confirmed that this misrepresentation was caused by the accumulation of optical retardation with depth. A simple method was proposed to numerically correct this optical-axis calculation. Experimental studies in tendon tissue demonstrated that this method can be applied to map the 2-D optical-axis distributions in ...

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    10. Single camera spectral domain polarization-sensitive optical coherence tomography using offset B-scan modulation

      Single camera spectral domain polarization-sensitive optical coherence tomography using offset B-scan modulation

      We report a simple implementation to acquire spectral domain polarization-sensitive optical coherence tomography (PSOCT) using a single camera. By combining a dual-delay assembly in the reference arm and offset B-scan in the sample arm, the orthogonal vertical- and horizontal-polarized images were acquired in parallel and spatially separated by a fixed distance in the full range image space. The two orthogonal polarization images were recombined to calculate the intensity, retardance and fast-axis images. This system was easy to implement and capable of acquiring high-speed in vivo 3D polarization-sensitive OCT images.

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  2. About University of Missouri

    University of Missouri

    University of Missouri (Mizzou, MU, University of Missouri–Columbia or simply Missouri) is a public research university located in the state of Missouri. In 1839 the university was founded in Columbia, Missouri, as the first public institution of higher education west of the Mississippi River. The largest university in Missouri, MU enrolls 33,805 students in 20 academic colleges in the 2011–12 year. The university is the flagship of the University of Missouri System which maintains campuses in Rolla, Kansas City and St. Louis. MU is one of 34 public universities to be members of the Association of American Universities and the only one in Missouri. There are more than 262,000 MU alumni living worldwide, with almost half continuing to reside in Missouri. The University of Missouri was ranked 90th in the 2012 U.S. News & World Report among the national universities, up four spots from 2011. It is the highest-ranked public school in the state and second overall (tied with Saint Louis University).