Articles that mention University of Minnesota -Optical Coherence Tomography News

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2. Ganglion Cell Layer Thickness Variance Using SPECTRALIS Optical Coherence Tomography
  
  Explore LWW Online Apr 17 2022 Ophthalmology
  
  Background: To determine the normal variance of the mean macular ganglion cell layer (GCL) volume among subjects without significant ocular pathology using SPECTRALIS optical coherence tomography (OCT). Methods: Fifty subjects underwent a baseline scan using SPECTRALIS OCT followed by 2 more studies with (reg-ON) and without (reg-OFF) eye registration all taken at the same session. The mean GCL volume was measured using built-in SPECTRALIS software. Eyes with macular pathology were ...
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  Mentions: University of Minnesota
3. In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
  
  Explore Home - ClinicalTrials.gov Dec 6 2021 Dentistry , Clinical Trials
  
  A recent review on clinical studies published on the performance of posterior composite restorations that were recalled at least up to 24-months reported that the overall failure rates for studies conducted between 2006-2016 was 13.13% and the two main reasons for failure in these two decades remained the same, i.e. secondary caries (25.68% - 29.47%) and composite fracture (28.84% - 39.07%). In in vitro studies, secondary ...
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  Mentions: University of Minnesota
4. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility
  
  Explore Nature Publishing Group Jun 12 2021 Cardiology
  
  The structural morphology of coronary stents (e.g. stent expansion, lumen scaffolding, strut apposition, tissue protrusion, side branch jailing, strut fracture), and the local hemodynamic environment after stent deployment are key determinants of procedural success and subsequent clinical outcomes. High-resolution intracoronary imaging has the potential to enable the geometrically accurate three-dimensional (3D) reconstruction of coronary stents. The aim of this work was to present a novel algorithm for 3D stent ...
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  Mentions: Massachusetts Institute of Technology Emory University Mount Sinai School of Medicine
5. Utilization of Optical Coherence Tomography to Assess Coronary Vessel Constriction after Ablation
  
  Explore ASME Digital Collection May 15 2021 Cardiology
  
  Epicardial ablations are being utilized as alternative techniques to the current endocardial procedures. An epicardial approach offers some advantages, especially when treating ventricular arrhythmias, e.g., those that have epicardial or transmural sites of origin. However the potential collateral damage from these applied myocardial surface ablations has not been fully explored. In order to better visualize and understand such effects on acute coronary functioning, we have employed intracoronary optical coherence ...
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  Mentions: University of Minnesota
6. Choroidal Vascular Changes in Acute Idiopathic Maculopathy as Demonstrated by Multimodal Imaging including Optical Coherence Tomography Angiography
  
  Explore Hindawi Publishing Corporation Apr 13 2021 Ophthalmology
  
  Purpose . To present a case of acute idiopathic maculopathy (AIM) and illustrate primary choroidal perfusion defect using multimodal imaging. Case Description . We report a case of a 24-year-old man with a paracentral scotoma of the right eye and recent flu-like illness. The patient was found to have a unilateral ovoid-shaped, placoid lesion just inferior to the fovea. Multimodal imaging confirmed findings most consistent with a diagnosis of acute idiopathic maculopathy ...
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  Mentions: Johns Hopkins University University of Minnesota
7. Smartphone-based Ophthalmic Imaging Compared With Spectral-domain Optical Coherence Tomography Assessment of Vertical Cup-to-disc Ratio Among Adults in Southwestern Uganda
  
  Explore LWW Online Mar 1 2021 Ophthalmology
  
  Precis: Using optical coherence tomography (OCT) measurements as a reference standard for vertical cup-to-disc ratio (vCDR), a smartphone-based ophthalmic camera has a sensitivity of 67.7% and specificity of 96.7% to detect a vCDR0.5. Purpose: The purpose of this study was to assess the performance of a smartphone-based ophthalmic camera system using an Apple iPhone 6S and an adapter, Paxos Scope, to obtain adequate dilated fundus photos to ...
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8. Association of Optical Coherence Tomography With Longitudinal Neurodegeneration in Veterans With Chronic Mild Traumatic Brain Injury
  
  Explore The JAMA Network Dec 23 2020 Neurology , Ophthalmology
  
  Importance: Mild traumatic brain injury (TBI) may predispose individuals to progressive neurodegeneration. Objective: To identify evidence of neurodegeneration through longitudinal evaluation of changes in retinal layer thickness using optical coherence tomography in veterans with a history of mild TBI. Design, setting, and participants: This longitudinal cohort study evaluated veterans who were receiving services at the Minneapolis Veterans Affairs Health Care System. Symptomatic or mild TBI was diagnosed according to the ...
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  Mentions: University of Minnesota
9. Sorptivity of water in enamel for categorizing caries lesions
  
  Explore ScienceDirect Sep 12 2020 Dentistry
  
  Objective The aim of this research was to determine the association between sorptivity of water and the state of mineralization in carious enamel of different stages of severity. Methods As a preliminary work, water droplets of 1.5 L were placed on the surfaces of hydroxyapatite (HA) discs of different densities. The water droplet profile was dynamically recorded every second over a period of 10 s using a contact angle ...
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  Mentions: University of Minnesota
10. Retinal Nerve Fibre Layer Thickness Increases with Decreasing Spectralis OCT Signal Strength in Normal Eyes
  
  Explore Taylor & Francis Online May 13 2020 Ophthalmology
  
  We sought to determine effect of signal strength on mean retinal nerve fibre layer (RNFL) using Spectralis optical coherence tomography (S-OCT). Thirty normal subjects (18 female, mean 37.9 years, range 24-61) were imaged with S-OCT using variably dense Bangerter foils to alter Q value (1 unit signal strength = 4 units Q). We found a statistically significant (p 0.01) linear relationship (R = 0.8643) between Q and RNFL (1 ...
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  Mentions: Heidelberg Engineering University of Minnesota
11. University of Minnesota Receives NIH Grant for Optical Imaging of Neural Activity Based on Lorentz Effect
  
  Explore Optical Coherence Tomography News Apr 8 2020 Funding
  
  ...the needed stability.
  
  University of Minnesota Receives a 2020 NIH Grant for $275,000 for Optical Imaging of Neural Activity Based on...
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  Mentions: National Institutes of Health University of Minnesota
12. Glioma cell migration dynamics in brain tissue assessed by multimodal optical imaging
  
  Explore ScienceDirect Aug 20 2019 Neurology
  
  Glioblastoma is a primary malignant brain tumor characterized by highly infiltrative glioma cells. Vasculature and white matter tracts are considered to be the preferred and fastest routes for glioma invasion through brain tissue. In this study, we systematically quantified the routes and motility of the U251 human glioblastoma cell line in mouse brain slices by multimodal imaging. Specifically, we used polarization-sensitive optical coherence tomography to delineate nerve fiber tracts while ...
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  Mentions: University of Minnesota
13. Contrast-enhanced serial optical coherence scanner with deep learning network reveals vasculature and white matter organization of mouse brain
  
  Explore SPIE Digital Library Jul 27 2019 Neurology
  
  Optical coherence tomography provides volumetric reconstruction of brain structure with micrometer resolution. Gray matter and white matter can be highlighted using conventional and polarization-based contrasts; however, vasculature in ex-vivo fixed brain has not been investigated at large scale due to lack of intrinsic contrast. We present contrast enhancement to visualize the vasculature by perfusing titanium dioxide particles transcardially into the mouse vascular system. The brain, after dissection and fixation, is ...
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  Mentions: University of Minnesota
14. Ruptures and Thickening : Optical Coherence Tomography as the Arbiter of the Fibrous Cap
  
  Explore ScienceDirect Jun 9 2018 Cardiology
  
  Coronary artery disease remains a leading cause of mortality worldwide, primarily through acute events mediated by progression and disruption of thrombosis-provoking atheroma. The necrotic core of advanced atheroma harbors highly prothrombotic material, including components of tissue factor, von Willebrand factor, and plasminogen activator inhibitor1. Exposure of these contents to flowing blood can spur thrombosis and is a critical feature of many acute coronary syndromes (ACS). It is therefore vital that ...
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  Mentions: Massachusetts General Hospital Harvard University University of Minnesota
15. Polarization-sensitive optical coherence tomography reveals gray matter and white matter atrophy in SCA1 mouse models
  
  Explore ScienceDirect May 19 2018 Neurology
  
  Spinocerebellar ataxia type 1 (SCA1) is a fatal inherited neurodegenerative disease. In this study, we demonstrate the label-free optical imaging methodology that can detect, with a high degree of sensitivity, discrete areas of degeneration in the cerebellum of the SCA1 mouse models. We used ATXN1[82Q] and ATXN1[30Q]-D776 mice in which the transgene is directed only to Purkinje cells. Molecular layer, granular layer, and white matter regions are ...
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  Mentions: University of Minnesota
16. Fully Automated Segmentation of Fluid/Cyst Regions in Optical Coherence Tomography Images With Diabetic Macular Edema Using Neutrosophic Sets and Graph Algorithms
  
  Explore IEEE Xplore Apr 19 2018 Ophthalmology
  
  ...y, the proposed algorithm also achieves sensitivity of 67.3%, 88.8%, and 76.7%, for the Duke, Optima, and the university of minnesota (UMN) datasets, respectively. ...
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  Mentions: University of Minnesota
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