1. University of Melbourne

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    1. Mentioned In 83 Articles

    2. Anterior segment optical coherence tomography angiography

      Anterior segment optical coherence tomography angiography
      We present a novel method to image the vasculature of the anterior segment of the eye using a non-invasive optical coherence tomography angiography (OCTA) system with a modified lens system. This system utilises the Heidelberg Spectralis OCTA and a 3D printed lens mount holding a simple biconvex lens in place to allow capture of images in the anterior segment.
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    3. Optical coherence tomography: seeing the unseen

      Optical coherence tomography: seeing the unseen
      ptical coherence tomography (OCT) is an imaging technology that has revolutionised the way we detect and manage ocular disease. Quite simply, it allows the clinician to visualise ocular pathology previously not detectable or only evident in advanced disease. OCT has its roots in ultrafast laser‐activated shutters to photograph light echoes, which allowed the depth of objects to be captured. Duguay and Mattick 1 at ATT Bell Laboratories in 1971 ...
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    4. Clozapine-Induced Myocarditis or Acute Coronary Syndrome? Optical Coherence Tomography to the Rescue

      Clozapine-Induced Myocarditis or Acute Coronary Syndrome? Optical Coherence Tomography to the Rescue
      Chest pain and troponin elevation may be due to an acute coronary syndrome, myocarditis, acute cardiomyopathy, or other less common conditions. Management differs depending on the aetiology, and the pathophysiologic diagnosis has direct implications on treatment and patient outcomes. History and clinical examination is supplemented by selected investigations including the electrocardiogram, chest X-ray, echocardiography, coronary angiography, and even myocardial perfusion scintigraphy or cardiac magnetic resonance imaging. Intravascular imaging can provide ...
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    5. An Automated Method for Choroidal Thickness Measurement from Enhanced Depth Imaging Optical Coherence Tomography Images

      An Automated Method for Choroidal Thickness Measurement from Enhanced Depth Imaging Optical Coherence Tomography Images
      The choroid is vascular tissue located underneath the retina and supplies oxygen to the outer retina; any damage to this tissue can be a precursor to retinal diseases. This paper presents an automated method of choroidal segmentation from enhanced depth imaging optical coherence tomography (EDI-OCT) images. The Dijkstra shortest path algorithm is used to segment the choroid-sclera interface (CSI), the outermost border of the choroid. A novel intensity-normalisation technique that ...
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    6. Qualitative and quantitative assessment of posterior segment optical coherence tomography images using standard photos: the Liwan Eye Study

      Qualitative and quantitative assessment of posterior segment optical coherence tomography images using standard photos: the Liwan Eye Study
      Background/aims To develop a standardised grading scheme, using standard photos, for spectral-domain ocular coherence tomography (SD-OCT) images of the posterior eye and evaluate the interobserver agreement among trained ophthalmologists in identifying pathological changes. Methods Subjects were recruited from Liwan District, Guangzhou, with SD-OCT data collection from June 2013 to November 2013 as part of 10-year follow-up visits from the Liwan Eye Study. All subjects underwent SD-OCT imaging of the ...
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    7. Automatic optical coherence tomography imaging analysis for retinal disease screening (Thesis)

      Automatic optical coherence tomography imaging analysis for retinal disease screening (Thesis)
      The retina and the choroid are two important structures of the eye and on which the quality of eye sight depends. They have many tissue layers which are very important for monitoring the health and the progression of the eye disease from an early stage. These layers can be visualised using Optical Coherence Tomography (OCT) imaging. The abnormalities in these layers are indications of several eye diseases that can lead ...
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    8. Coronary optical coherence tomography-derived virtual fractional flow reserve (FFR): anatomy and physiology all-in-one | European Heart Journal

      Coronary optical coherence tomography-derived virtual fractional flow reserve (FFR): anatomy and physiology all-in-one | European Heart Journal
      Most invasive coronary imaging modalities only provide anatomical information from which physiologic significance is inferred. Fractional flow reserve (FFR) and other physiologic indices of lesion severity are more reliable methods to identify physiologically significant lesions. Currently, accomplishing both anatomic and physiologic interrogation of an intermediate coronary stenosis requires the use of multiple devices within the coronary artery. Coronary angiography, optical coherence tomography (OCT), and FFR were performed in a left ...
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    9. Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology

      Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology
      ntracranial atherosclerosis is a major cause of ischemic stroke. Patients with a high degree of stenosis have a significant rate of stroke despite medical therapy. Two randomized trials of stenting have failed to show benefit. Improving peri-procedural complication rates and patient selection may improve stenting outcomes. Fractional flow reserve (FFR), intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are intravascular imaging techniques employed to improve patient selection and stent placement ...
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    10. Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment

      Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment
      Background: With increasing interest in determining if measurement of retinal neuronal structure with spectral-domain optical coherence tomography (SD-OCT) is useful in accessing neurodegenerative process in cognitive decline and development of dementia, it is important to evaluate whether the SD-OCT measurements are repeatable and reproducible in patients with Alzheimers disease (AD) or mild cognitive impairment (MCI). Methods: This is a retrospective cohort study. Patients with AD or MCI with no change ...
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    11. Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search

      Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search
      We present a novel framework combining convolutional neural networks (CNN) and graph search methods (termed as CNN-GS) for the automatic segmentation of nine layer boundaries on retinal optical coherence tomography (OCT) images. CNN-GS first utilizes a CNN to extract features of specific retinal layer boundaries and train a corresponding classifier to delineate a pilot estimate of the eight layers. Next, a graph search method uses the probability maps created from ...
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    12. Automatic Identification of Pathology-Distorted Retinal Layer Boundaries Using SD-OCT Imaging

      Automatic Identification of Pathology-Distorted Retinal Layer Boundaries Using SD-OCT Imaging
      Objective: We propose an effective automatic method for identification of four retinal layer boundaries from the spectral domain optical coherence tomography images in the presence and absence of pathologies and morphological changes due to disease. Methods: The approach first finds an approximate location of three reference layers and then uses these to bound the search space for the actual layers, which is achieved by modeling the problem as a graph ...
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    13. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study

      Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
      Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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    14. Optical Coherence Tomography Reveals Changes to Corneal Reflectivity and Thickness in Individuals with Tear Hyperosmolarity

      Optical Coherence Tomography Reveals Changes to Corneal Reflectivity and Thickness in Individuals with Tear Hyperosmolarity
      Purpose : To investigate whether tear hyperosmolarity, a feature of dry eye disease (DED), affects central corneal thickness (CCT), corneal light reflectivity, and/or tear film reflectivity. Methods : This prospective, cross-sectional study involved 48 participants (38 with hyperosmolar tears and 10 controls with normo-osmolar tears). Symptoms and signs of DED (tear osmolarity, sodium fluorescein tear break-up time, ocular surface staining, Schirmer test) were assessed. CCT, and the reflectivity of the cornea ...
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  2. About University of Melbourne

    University of Melbourne

    University of Melbourne, is a public university located in Melbourne, Victoria. The second oldest university in Australia, and the oldest in Victoria, its main campus is in Parkville, an inner suburb just north of the Melbourne CBD. Other campuses across Melbourne and rural Victoria have been acquired through amalgamation with smaller colleges of advanced education. It is a member of Australia's "Group of Eight" lobby group, and the Sandstone universities. Melbourne University is ranked amongst the top universities both in Australia and the world. The University is highly regarded in the fields of the arts, humanities, and biomedicine. The University has almost 40,000 students, who are supported by nearly 6,000 staff members (full or part-time).