1. University of Melbourne

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    1. Mentioned In 107 Articles

    2. Impact of Reticular Pseudodrusen on Choriocapillaris Flow Deficits and Choroidal Structure on Optical Coherence Tomography Angiography

      Impact of Reticular Pseudodrusen on Choriocapillaris Flow Deficits and Choroidal Structure on Optical Coherence Tomography Angiography
      Purpose: To examine the impact of reticular pseudodrusen (RPD) on choriocapillaris blood flow and choroidal structure in individuals with intermediate age-related macular degeneration (AMD). Methods: Individuals with bilateral large drusen underwent optical coherence tomography (OCT), color fundus photography, near-infrared reflectance, and fundus autofluorescence imaging to determine the presence of RPD. These participants also underwent swept-source OCT angiography (SS-OCTA) imaging to determine (1) choriocapillaris flow deficit (FD) parameters, including the percentage ...
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    3. A deep learning model for automated segmentation of geographic atrophy imaged with swept-source optical coherence tomography images

      A deep learning model for automated segmentation of geographic atrophy imaged with swept-source optical coherence tomography images
      Purpose: To present a deep-learning algorithm for the segmentation of geographic atrophy (GA) using en face swept-source optical coherence tomography (SS-OCT) images that is accurate and reproducible for the assessment of GA growth over time. Design: Retrospective review of images obtained as part of a prospective natural history study Subjects: Patients with GA (90), early/intermediate AMD (32), healthy controls (16) METHODS: An automated algorithm utilizing scan volume data to ...
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    4. Correcting magnification error in foveal avascular zone area measurements of optical coherence tomography angiography images with estimated axial length

      Correcting magnification error in foveal avascular zone area measurements of optical coherence tomography angiography images with estimated axial length
      Background: To generate and validate a method to estimate axial length estimated (AL est ) from spherical equivalent (SE) and corneal curvature [keratometry (K)], and to determine if this AL est can replace actual axial length (AL act ) for correcting transverse magnification error in optical coherence tomography angiography (OCTA) images using the Littmann-Bennett formula. Methods: Data from 1301 participants of the Raine Study Gen2-20 year follow-up were divided into two datasets ...
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    5. Case Series: Presumed Choroidal Melanoma Diagnosis Expedited by Documented Growth on Serial Optical Coherence Tomography

      Case Series: Presumed Choroidal Melanoma Diagnosis Expedited by Documented Growth on Serial Optical Coherence Tomography
      Significance: These cases highlight the importance of monitoring choroidal nevi with benign imaging characteristics and the potential to quantify horizontal growth using optical coherence tomography (OCT), in the absence of color fundus photography. Purpose: This study aimed to present reports of two patients with pigmented choroidal tumors with low malignant potential based on their multimodal imaging features at the time of referral, but access to prior OCT imaging confirmed horizontal ...
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    6. A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours

      A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours
      Purpose: The prognostic value of optical coherence tomography (OCT) of the macular ganglion cell layer (mGGL) versus peripapillary retinal nerve fibre layers (pRNFL) following chiasmal decompression is unclear. This study is the largest comparison of the two parameters to date and aims to clarify how their performance as covariates compare in predictive models of long-term visual outcomes following pituitary or parasellar tumour surgical resection. Methods: This was a prospective, two-year ...
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    7. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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    8. Towards standardizing retinal optical coherence tomography angiography: a review

      Towards standardizing retinal optical coherence tomography angiography: a review
      The visualization and assessment of retinal microvasculature are important in the study, diagnosis, monitoring, and guidance of treatment of ocular and systemic diseases. With the introduction of optical coherence tomography angiography (OCTA), it has become possible to visualize the retinal microvasculature volumetrically and without a contrast agent. Many lab-based and commercial clinical instruments, imaging protocols and data analysis methods and metrics, have been applied, often inconsistently, resulting in a confusing ...
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    9. Optical Coherence Tomography of Coronary Plaque Progression and Destabilization: JACC Focus Seminar Part 3/3

      Optical Coherence Tomography of Coronary Plaque Progression and Destabilization: JACC Focus Seminar Part 3/3
      The development of optical coherence tomography (OCT) has revolutionized our understanding of coronary artery disease. In vivo OCT research has paralleled with advances in computational fluid dynamics, providing additional insights in the various hemodynamic factors influencing plaque growth and stability. Recent OCT studies introduced a new concept of plaque healing in relation to clinical presentation. In addition to known mechanisms of acute coronary syndromes such as plaque rupture and plaque ...
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    10. The eye in migraine: a review of retinal imaging findings in migraine

      The eye in migraine: a review of retinal imaging findings in migraine
      Migraine is a common headache disorder with neurovascular involvement. Because eyecare practitioners are likely to encounter people with migraine in their everyday practice, it is important to understand how migraine might impact on ocular health. In this narrative review, we provide an update on the latest ophthalmic imaging evidence for retinal involvement in migraine, derived from studies of retinal structure and retinal vascular perfusion using spectral domain and swept source ...
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    11. Optical coherence tomography in ablation-related coronary artery injury

      Optical coherence tomography in ablation-related coronary artery injury
      A 43-year-old male with recurrent atrioventricular re-entrant tachycardia refractory to adenosine, amiodarone, and intravenous flecainide underwent a right femoral access radiofrequency ablation (RFA) using four sheaths (6F, 7F, 28F). The procedure was performed using TactiCath DF irrigated contact force ablation catheter and EnSite Precision 3D mapping system (Abbott Laboratories, Chicago, IL, USA). Earliest atrial activation was found at the middle coronary sinus (CS) electrodes. Following trans-septal puncture to access the ...
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    12. A normative database of A-scan data using the Heidelberg Spectralis Spectral Domain Optical Coherence Tomography machine

      A normative database of A-scan data using the Heidelberg Spectralis Spectral Domain Optical Coherence Tomography machine
      Purpose To develop the first normative database of macular and circumpapillary scans with reference values at the level of the A-scan using the Heidelberg Spectralis Optical Coherence Tomography (OCT) machine. Methods This study is a retrospective cross sectional analysis of macular and circumpapillary OCT scans of healthy individuals. All participants had a full ophthalmic examination, including best corrected visual acuity, intraocular pressure, biomicroscopy, posterior segment examination and OCT scan. The ...
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    13. The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

      The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
      Objective: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. Methods: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial ...
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    14. OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6

      OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6
      Objective: To determine the inter-reader agreement for incomplete and complete retinal pigment epithelium and outer retinal atrophy (iRORA and cRORA respectively) and their related features in age-related macular degeneration (AMD). Design: Inter-reader agreement study. Participants: Twelve readers from six reading centers. Methods: Following formal training, readers qualitatively assessed 60 optical coherence tomography (OCT) B-scans from 60 eyes with AMD for nine individual features associated with early atrophy and performed seven ...
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    15. A Normative Database of A-Scan Data Using the Heidelberg Spectralis Spectral Domain Optical Coherence Tomography Machine

      A Normative Database of A-Scan Data Using the Heidelberg Spectralis Spectral Domain Optical Coherence Tomography Machine
      Purpose Develop the first normative database of macular and circumpapillary scans with reference values at the level of the A-scan using the Heidelberg Spectralis Optical Coherence Tomography (OCT) machine. Methods This study is a retrospective cross sectional analysis of macular and circumpapillary OCT scans of healthy individuals. All participants had a full ophthalmic examination, including best corrected visual acuity, intraocular pressure, biomicroscopy, posterior segment examination and OCT scan. The volume ...
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    16. Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography

      Objective quantification of lens nuclear opacities using swept-source anterior segment optical coherence tomography
      Background/aims: The primary objective is to quantify the lens nuclear opacity using swept-source anterior segment optical coherence tomography (SS-ASOCT) and to evaluate its correlations with Lens Opacities Classification System III (LOCS-III) system and surgical parameters. The secondary objective is to assess the diagnostic performance for hard nuclear cataract. Methods: This cross-sectional study included 1222 patients eligible for cataract surgery (1222 eyes). The latest SS-ASOCT (CASIA-2) was used to obtain ...
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  2. About University of Melbourne

    University of Melbourne

    University of Melbourne, is a public university located in Melbourne, Victoria. The second oldest university in Australia, and the oldest in Victoria, its main campus is in Parkville, an inner suburb just north of the Melbourne CBD. Other campuses across Melbourne and rural Victoria have been acquired through amalgamation with smaller colleges of advanced education. It is a member of Australia's "Group of Eight" lobby group, and the Sandstone universities. Melbourne University is ranked amongst the top universities both in Australia and the world. The University is highly regarded in the fields of the arts, humanities, and biomedicine. The University has almost 40,000 students, who are supported by nearly 6,000 staff members (full or part-time).