1. University of Manitoba

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    1. Mentioned In 31 Articles

    2. Fast simulation of finite-beam optical coherence tomography of inhomogeneous turbid media (Thesis)

      Fast simulation of finite-beam optical coherence tomography of inhomogeneous turbid media (Thesis)
      We developed a fast simulator of finite-beam optical coherence tomography (OCT) of inhomogeneous turbid media. Our Sequential Monte Carlo (MC) based finite beam OCT simulator can reach more than a hundred times faster than one that represents a finite OCTs incident beam as a superposition of infinitely thin beams, i.e., a superposition-based MC simulator. In this thesis, first, we highlight the lesser-known correspondence between the commonly used MC simulation ...
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    3. Scaled nonuniform Fourier transform for image reconstruction in swept source optical coherence tomography

      Scaled nonuniform Fourier transform for image reconstruction in swept source optical coherence tomography
      Swept Source optical coherence tomography (SS-OCT) is an important imaging modality for both medical and industrial diagnostic applications. A cross-sectional SS-OCT image is obtained by applying an inverse discrete Fourier transform (DFT) to axial interferograms measured in the frequency domain (k-space). This inverse DFT is typically implemented as a fast Fourier transform (FFT) that requires the data samples to be equidistant in k-space. As the frequency of light produced by ...
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    4. Design and Implementation of Full Field-Optical Coherence Tomography on an Olympus IX73 Microscope (Thesis)

      Design and Implementation of Full Field-Optical Coherence Tomography on an Olympus IX73 Microscope (Thesis)
      Optical Coherence Tomography (OCT) has established itself as an important imaging technology for biomedical and industrial applications. In this thesis, we describe the design and implementation of a novel Full-Field OCT optical module that is specifically designed to fit inside an Olympus IX73 inverted microscope. We describe the design, components, and implementation of this novel optical module in detail. The resulting FF-OCT setup (microscope and OCT optical module) can be ...
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    5. Massively parallel simulator of optical coherence tomography of inhomogeneous turbid media

      Massively parallel simulator of optical coherence tomography of inhomogeneous turbid media
      Background and objective An accurate and practical simulator for Optical Coherence Tomography (OCT) could be an important tool to study the underlying physical phenomena in OCT such as multiple light scattering. Recently, many researchers have investigated simulation of OCT of turbid media, e.g., tissue, using Monte Carlo methods. The main drawback of these earlier simulators is the long computational time required to produce accurate results. We developed a massively ...
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    6. Restoration of optical coherence tomography images using stochastic methods (Thesis)

      Restoration of optical coherence tomography images using stochastic methods (Thesis)
      Optical coherence tomography (OCT) is a rapidly growing imaging modality that produces high resolution three dimensional images that can be applied to different medical and industrial applications . Obtaining higher depth of imaging and higher imaging quality are important goals in OCT systems. One of the main factors that affects the penetration depth and imaging quality of OCT systems is the presence of noise. The depth-scan photocurrent of time domain (TD ...
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    7. Detection of Atherosclerotic Plaque from Optical Coherence Tomography Images Using Texture-Based Segmentation

      Detection of Atherosclerotic Plaque from Optical Coherence Tomography Images Using Texture-Based Segmentation
      Detection of atherosclerotic plaque from optical coherence tomography (OCT) images by visual inspection is difficult. We developed a texture based segmentation method to identify atherosclerotic plaque automatically from OCT images without any reliance on visual inspection. Our method involves extraction of texture statistical features (spatial gray level dependence matrix method), application of an unsupervised clustering algorithm (K-means) on these features, and mapping of the clustered regions: background, plaque, vascular tissue ...
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    8. Accelerated simulation of optical coherence tomography of objects with arbitrary spatial distributions

      Accelerated simulation of optical coherence tomography of objects with arbitrary spatial distributions
      We developed a highly parallel simulator of Optical Coherence Tomography (OCT) of objects with arbitrary spatial distributions. This Monte Carlo method based simulator models the object as a tetrahedron-based mesh, and implements an advanced importance sampling scheme. This new method makes OCT simulations more practical, since the corresponding serial Central Processing Unit (CPU) based implementation requires approximately 360 hours to simulate OCT imaging of a single B-scan. We implemented this ...
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    9. Monte Carlo simulation of optical coherence tomography for turbid media with arbitrary spatial distributions

      Monte Carlo simulation of optical coherence tomography for turbid media with arbitrary spatial distributions
      We developed a Monte Carlo-based simulator of optical coherence tomography (OCT) imaging for turbid media with arbitrary spatial distributions. This simulator allows computation of both Class I diffusive reflectance due to ballistic and quasiballistic scattered photons and Class II diffusive reflectance due to multiple scattered photons. It was implemented using a tetrahedron-based mesh and importance sampling to significantly reduce computational time. Our simulation results were verified by comparing them with ...
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    10. Texture based segmentation method to detect atherosclerotic plaque from optical tomography images

      Texture based segmentation method to detect atherosclerotic plaque from optical tomography images
      Optical coherence tomography (OCT) imaging has been widely employed in assessing cardiovascular disease. Atherosclerosis is one of the major cause cardio vascular diseases. However visual detection of atherosclerotic plaque from OCT images is often limited and further complicated by high frame rates. We developed a texture based segmentation method to automatically detect plaque and non plaque regions from OCT images. To verify our results we compared them to photographs of ...
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    11. Maximization of signal-to-noise ratio in optical coherence tomography using a depth-dependent matched filter

      Maximization of signal-to-noise ratio in optical coherence tomography using a depth-dependent matched filter
      We discuss and demonstrate the dependence of noise on the signal in time-domain optical coherence tomography (TDOCT). We then derive a depth-dependent matched filter to maximize the signal-to-noise ratio at every pixel in a depth scan (A-scan). We use an empirical estimate of the second order statistics of the noise in OCT images of vascular tissue to implement a depth-dependent filter that is matched to these images. The application of ...
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    12. Detection of atherosclerotic vascular tissue from optical coherence tomography images

      Detection of atherosclerotic vascular tissue from optical coherence tomography images
      Atherosclerotic coronary artery disease continues to be one of the major causes of mortality. Prevention, diagnosis and treatment of atherosclerotic coronary artery disease are dependent on the detection of high risk atherosclerotic plaque. As age is one of the most important risk factors, atherosclerosis worsens steadily with increasing age. Automatic characterization of atherosclerotic plaque using the optical coherence tomography (OCT) images provides a powerful tool to classify patients with high ...
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    13. Fast calculation of multipath diffusive reflectance in optical coherence tomography

      Fast calculation of multipath diffusive reflectance in optical coherence tomography
      We show how to efficiently calculate the signal in optical coherence tomography (OCT) systems due to the ballistic photons, the quasi-ballistic photons, and the photons that undergo multiple diffusive scattering using Monte Carlo simulations with importance sampling. This method enables the calculation of these three components of the OCT signal with less than one hundredth of the computational time required by the conventional Monte Carlo method. Therefore, it can be ...
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    14. Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications

      Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications
      The advances made in the last two decades in interference technologies, optical instrumentation, catheter technology, optical detectors, speed of data acquisition and processing as well as light sources have facilitated the transformation of optical coherence tomography from an optical method used mainly in research laboratories into a valuable tool applied in various areas of medicine and health sciences. This review paper highlights the place occupied by optical coherence tomography in ...
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    15. Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?

      Optical Coherence Tomography Used $500M of Federally Funded Research Over The Past Decade: How was it Used, What was Accomplished, and What’s to Come?
      ... $743,746 Ontario Cancer Institute $458,447 École Polytechnique de Montréal $421,314 University of Manitoba $371,968 University of Victoria $248,025 Queen's University $212,130...
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    16. 1-15 of 31 1 2 »
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  2. About University of Manitoba

    University of Manitoba

    University of Manitoba is western Canada's first university. Founded more than 130 years ago and located in the heart of the country, we are the region’s largest and only research intensive university in excess of 90 degrees, diplomas, and certificates – more than 60 at the undergraduate level including professional disciplines such as medicine, law, and engineering