1. University of Manchester

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    1. Mentioned In 64 Articles

    2. Image analysis of optical coherence tomography scans to explore established and novel choroidal features in patients with central serous chorioretinopathy

      Image analysis of optical coherence tomography scans to explore established and novel choroidal features in patients with central serous chorioretinopathy
      Purpose: To explore the characteristics of choroidal tissue in patients with and without central serous chorioretinopathy (CSC) using an automated system of image analysis to determine known and novel metrics. Methods: This was a retrospective case-control analysis of optical coherence tomography (OCT) scans of patients seen at Manchester Royal Eye Hospital, UK, comparing patients with active CSC to an age and gender-matched group with no CSC using a purpose-built automated ...
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    3. A Mixed Quantitative and Qualitative Study to Develop and Evaluate the Application of Artificial Intelligence (AI) Methods Using Retinal Imaging for the Identification of Adverse Retinal Changes Associated With Cancer Therapies.

      A Mixed Quantitative and Qualitative Study to Develop and Evaluate the Application of Artificial Intelligence (AI) Methods Using Retinal Imaging for the Identification of Adverse Retinal Changes Associated With Cancer Therapies.
      This is a data collection study involving the gathering of clinical data and OCT ( optical coherence tomography ) scans from 350 patients. The purpose of this study is to gather data to help develop an AI algorithm to detect eye abnormalities specifically those related to certain cancer treatments. At the end of the study interviews will be held with expert ophthalmologists to assess the acceptability of implementing AI into clinical practice.
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    4. https://doi.org/10.1002/14651858.CD013855

      https://doi.org/10.1002/14651858.CD013855
      Background: Caries is one of the most prevalent and preventable conditions worldwide. If identified early enough then non-invasive techniques can be applied, and therefore this review focusses on early caries involving the enamel surface of the tooth. The cornerstone of caries detection and diagnosis is a visual and tactile dental examination, although alternative approaches are available. These include illumination-based devices that could potentially support the dental examination. There are three ...
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    5. Macular fibrosis in Coats’ disease demonstrated by Optical Coherence Tomography Angiography – new data toward pathophysiology

      Macular fibrosis in Coats’ disease demonstrated by Optical Coherence Tomography Angiography – new data toward pathophysiology
      Purpose: To analyze if Segmented Swept-Source Optical Coherence Tomography Angiography (SS OCT-A) can provide additional information on morphology and pathophysiology of macular fibrosis in Coats' patients. Methods: A consecutive case series of three male patients (5, 7 and 15 years old), with Coats' disease-related macular fibrosis (stage 2b-2 patients, 3b-1 patient). SS OCT-A 33 mm macular scans of affected eyes were performed. Results: In all three cases the inner portion ...
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    6. Detection of Pre-clinical Involvement of the Second Eye in Viral Acute Retinal Necrosis Using Optical Coherence Tomography

      Detection of Pre-clinical Involvement of the Second Eye in Viral Acute Retinal Necrosis Using Optical Coherence Tomography
      Purpose To report the detection of retinitis in the second eye of a patient with viral acute retinal necrosis (ARN), before the appearance of clinical change, using swept-source optical coherence tomography. Results A 63 year-old male developed right-sided varicella-zoster virus (VZV) ARN, confirmed with aqueous sampling. High-dose intravenous aciclovir caused renal impairment and was suspended for two-days. One day later, left eye macular SS-OCT revealed focal retinal thickening and disruption ...
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    7. Differentiation of Diabetic Status Using Statistical and Machine Learning Techniques on Optical Coherence Tomography Angiography Images

      Differentiation of Diabetic Status Using Statistical and Machine Learning Techniques on Optical Coherence Tomography Angiography Images
      Purpose : To investigate the potential of statistical and machine learning approaches to determine the diabetic status of patients from optical coherence tomography angiography (OCT-A) images. Methods : This was a retrospective cross-sectional observational study based at Manchester Royal Eye Hospital, United Kingdom. OCT-A scans were sequentially selected from one eye of each of 182 patients who were either not diabetic, diabetic without retinopathy, or diabetic with retinopathy requiring hospital follow-up. Eligible ...
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    8. Intra and inter-rater agreement of inflammatory choroidal neovascular membrane measurements using optical coherence tomography angiography

      Intra and inter-rater agreement of inflammatory choroidal neovascular membrane measurements using optical coherence tomography angiography
      Purpose Automated measurement algorithm software is not routinely available in optical coherence tomography angiography (OCTA) devices and manual measurement of choroidal neovascular membrane (CNVM) size is necessary. Our aim was to determine intra- and inter-rater agreement of inflammatory CNVM manual measurements obtained with OCTA. Methods OCTA (Triton Topcon Corporation) images in patients with inflammatory CNVM were imported into ImageJ software v1.50 (NIH image). Two experienced observers performed manual area ...
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    9. Swept-Source Optical Coherence Tomography Angiography Assessment Of Fellow Eyes In Coats Disease

      Swept-Source Optical Coherence Tomography Angiography Assessment Of Fellow Eyes In Coats Disease
      Purpose: To assess foveal and parafoveal vasculature at superficial capillary plexus (SCP), deep capillary plexus, and choriocapillaris using optical coherence tomography angiography in the fellow eyes of patients with Coats disease . Methods: Observational and prospective case series. Thirteen patients with unilateral Coats and 14 healthy age- and sex-matched controls were consecutively recruited at Manchester Royal Eye Hospital and the Department of Ophthalmology of San Raffaele Hospital. Both groups underwent complete ...
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    10. Dynamic Optical Coherence Tomography Is a New Technique for Imaging Skin Around Lower Extremity Wounds

      Dynamic Optical Coherence Tomography Is a New Technique for Imaging Skin Around Lower Extremity Wounds
      Chronic wounds such as venous leg ulcers invariably heal slowly and recur. In the case of venous leg ulcers, poor healing of chronic wounds is variously attributed to ambulatory hypertension, impaired perfusion and diffusion, presence of chronic inflammation at wound sites, lipodermatosclerosis, and senescence. The aim of this study was to investigate whether a new technique, optical coherence tomography (OCT), which permits imaging of blood capillaries in the peri-wound skin ...
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    11. The effect of bevacizumab before vitrectomy for diabetic tractional retinal detachment demonstrated on optical coherence tomography angiography

      The effect of bevacizumab before vitrectomy for diabetic tractional retinal detachment demonstrated on optical coherence tomography angiography
      Purpose To demonstrate the effect of intravitreal bevacizumab (IVB) on the size and vascularity of the fibro-vascular complex with the optical coherence tomography angiography (OCTA) before pars plana vitrectomy (PPV). Methods Observational case series of three eyes with active diabetic fibro-vascular complex and tractional retinal detachment (TRD) who underwent IVB (1.25 mg/0.05 ml) two days before proceeding to PPV. OCTA was carried out prior to IVB, two ...
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    12. Features of choroidal naevi on swept source optical coherence tomography angiography and structural reverse flow optical coherence tomography

      Features of choroidal naevi on swept source optical coherence tomography angiography and structural reverse flow optical coherence tomography
      Purpose The purpose of our study was to describe features of choroidal naevi as seen on swept source optical coherence tomography angiography (OCTA) and also on en face images derived from structural data from OCTA. Methods A prospective observational cohort study was carried out. Patients attending a specialised choroidal naevomelanocytic with known naevi were imaged with swept source OCTA. Results Seventy-one eyes of 70 patients were imaged. Forty-three patients and ...
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    13. Research Associate in Integrated ‘on-chip’ optical coherence tomography (OCT) for point-of-care imaging diagnostics

      Research Associate in Integrated ‘on-chip’ optical coherence tomography (OCT) for point-of-care imaging diagnostics
      A Postdoctoral Research Associate position is available for an outstanding ambitious physicist or electrical/electronic engineer with a strong publication track record to undertake world class research into advanced silicon photonic materials and devices, primarily for applications in on-chip optical coherence tomography. You will take a lead role in the simulation/modelling, design and characterization of silicon/silicon nitride waveguide based devices such as those incorporating broadband interferometers. You will ...
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    14. Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report

      Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report
      Purpose: To describe perifoveal microvascular changes occurring in X-linked juvenile retinoschisis (XLRS) using swept source optical coherence tomography angiography (SS OCTA). Patients and methods: This is a serial case report of three patients. Retrospective data of patients affected by XLRS were collected. Structural optical coherence tomography (OCT) and color fundus photography (CFPh) were carried out with Topcon OCT 2000 3D OCT as part of the standard care. Two patients were ...
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  2. About University of Manchester

    University of Manchester

    The University of Manchester is a university located in Manchester, England. With over 40,000 students studying 500 academic programmes, more than 10,000 staff and an annual income of nearly £600 million it is the largest single-site University in the United Kingdom. The Photon Science Institute at The University of Manchester aims to be an internationally leading centre of excellence in photon science — “light for science”. The Institute will deliver high quality fundamental and applied research, accessible postgraduate education and tailored industrial training. By disseminating its knowledge and expertise the Institute will forge strong business relationships.