1. University of Manchester

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    1. Mentioned In 54 Articles

    2. The effect of bevacizumab before vitrectomy for diabetic tractional retinal detachment demonstrated on optical coherence tomography angiography

      The effect of bevacizumab before vitrectomy for diabetic tractional retinal detachment demonstrated on optical coherence tomography angiography
      Purpose To demonstrate the effect of intravitreal bevacizumab (IVB) on the size and vascularity of the fibro-vascular complex with the optical coherence tomography angiography (OCTA) before pars plana vitrectomy (PPV). Methods Observational case series of three eyes with active diabetic fibro-vascular complex and tractional retinal detachment (TRD) who underwent IVB (1.25 mg/0.05 ml) two days before proceeding to PPV. OCTA was carried out prior to IVB, two ...
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    3. Features of choroidal naevi on swept source optical coherence tomography angiography and structural reverse flow optical coherence tomography

      Features of choroidal naevi on swept source optical coherence tomography angiography and structural reverse flow optical coherence tomography
      Purpose The purpose of our study was to describe features of choroidal naevi as seen on swept source optical coherence tomography angiography (OCTA) and also on en face images derived from structural data from OCTA. Methods A prospective observational cohort study was carried out. Patients attending a specialised choroidal naevomelanocytic with known naevi were imaged with swept source OCTA. Results Seventy-one eyes of 70 patients were imaged. Forty-three patients and ...
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    4. Research Associate in Integrated ‘on-chip’ optical coherence tomography (OCT) for point-of-care imaging diagnostics

      Research Associate in Integrated ‘on-chip’ optical coherence tomography (OCT) for point-of-care imaging diagnostics
      A Postdoctoral Research Associate position is available for an outstanding ambitious physicist or electrical/electronic engineer with a strong publication track record to undertake world class research into advanced silicon photonic materials and devices, primarily for applications in on-chip optical coherence tomography. You will take a lead role in the simulation/modelling, design and characterization of silicon/silicon nitride waveguide based devices such as those incorporating broadband interferometers. You will ...
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    5. Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report

      Segmented swept source optical coherence tomography angiography assessment of the perifoveal vasculature in patients with X-linked juvenile retinoschisis: a serial case report
      Purpose: To describe perifoveal microvascular changes occurring in X-linked juvenile retinoschisis (XLRS) using swept source optical coherence tomography angiography (SS OCTA). Patients and methods: This is a serial case report of three patients. Retrospective data of patients affected by XLRS were collected. Structural optical coherence tomography (OCT) and color fundus photography (CFPh) were carried out with Topcon OCT 2000 3D OCT as part of the standard care. Two patients were ...
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    6. Quantitative Swept-Source Optical Coherence Tomography of Early Enamel Erosion in vivo

      Quantitative Swept-Source Optical Coherence Tomography of Early Enamel Erosion in vivo
      Swept-source optical coherence tomography (SS-OCT) shows potential for the in vivo quantitative evaluation of micro-structural enamel surface phenomena occurring during early erosive demineralization. This randomized controlled single-blind cross-over clinical study aimed to evaluate the use of SS-OCT for detecting optical changes in the enamel of 30 healthy volunteers subjected to orange juice rinsing (erosive challenge) in comparison to mineral water rinsing (control), according to wiped and non-wiped enamel surface states ...
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    7. Elastic turbulence in entangled semi-dilute DNA solutions measured with optical coherence tomography velocimetry

      Elastic turbulence in entangled semi-dilute DNA solutions measured with optical coherence tomography velocimetry
      The flow instabilities of solutions of high molecular weight DNA in the entangled semi-dilute concentration regime were investigated using optical coherence tomography velocimetry, a technique that provides high spatial (probe volumes of 3.4 pL) and temporal resolution (sub s) information on the flow behaviour of complex fluids in a rheometer. The velocity profiles of the opaque DNA solutions (high and low salt) were measured as a function of the ...
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    8. Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial
      Aims: The purpose of this study was to assess the vascular response and vessel healing of overlapped Absorb scaffolds (Abbott Vascular, Santa Clara, CA, USA) compared to non-overlapped devices in human coronary arteries as assessed by optical coherence tomography (OCT) in the same treated segment. Methods and results: The ABSORB EXTEND (NCT01023789) trial is a prospective, single-arm, openlabel clinical study which enrolled 800 patients. The planned overlap OCT subgroup in ...
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    9. Coronary bifurcation treated with the hybrid mini-crush approach: a potential application of three-dimensional optical coherence tomography to optimise stent apposition - See more at: http://www.pcronline.com/eurointervention/91st_issue/volume-11/number-8

      Coronary bifurcation treated with the hybrid mini-crush approach: a potential application of three-dimensional optical coherence tomography to optimise stent apposition - See more at: http://www.pcronline.com/eurointervention/91st_issue/volume-11/number-8
      A 55-year-old male underwent an exercise treadmill test which was positive at stage 1. Coronary angiography (Figure 1A, Moving image 1) demonstrated a long segment of disease in the proximal-mid left anterior descending (LAD) artery. A fractional flow reserve study was positive at 0.71, with no localising lesion on hyperaemic pullback. In addition, 5 mm disease was present in the ostial-proximal first diagonal. A hybrid mini-crush approach was adopted ...
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    10. Lasers and SLEDs for optical coherence tomography

      Lasers and SLEDs for optical coherence tomography
      Optical coherence tomography (OCT) allows for the generation of 3D tomographic images of sub-surface structures in-vivo. This non-destructive, non-ionising process has found application in biological science and clinical diagnosis. Specifically, two versions of the OCT technique have proved optimal for different applications. For retinal imaging through a long length of water, near infrared wavelength super-luminescent diodes (SLEDs) with silicon array detector spectrometer systems have dominated. For imaging turbid media such ...
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    11. Skin substitute-assisted repair shows reduced dermal fibrosis in acute human wounds validated simultaneously by histology and optical coherence tomography

      Skin substitute-assisted repair shows reduced dermal fibrosis in acute human wounds validated simultaneously by histology and optical coherence tomography
      Skin substitutes are heterogeneous biomaterials designed to accelerate wound healing through provision of replacement extracellular matrix. Despite growing evidence for their use in chronic wounds, the role of skin substitutes in acute wound management and their influence upon fibrogenesis remains unclear. Skin substitute characteristics including biocompatibility, porosity and elasticity strongly influence cellular behaviour during wound healing. Thus, we hypothesise that structural and biomechanical variation between biomaterials may induce differential scar ...
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  2. About University of Manchester

    University of Manchester

    The University of Manchester is a university located in Manchester, England. With over 40,000 students studying 500 academic programmes, more than 10,000 staff and an annual income of nearly £600 million it is the largest single-site University in the United Kingdom. The Photon Science Institute at The University of Manchester aims to be an internationally leading centre of excellence in photon science — “light for science”. The Institute will deliver high quality fundamental and applied research, accessible postgraduate education and tailored industrial training. By disseminating its knowledge and expertise the Institute will forge strong business relationships.