Articles that mention University of Lübeck -Optical Coherence Tomography News

University of Lübeck

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1. Mentioned In 100 Articles
2. MUcociliary Clearance IN Stroke
  
  Explore Home - ClinicalTrials.gov Mar 21 2019 Pulmonology , Clinical Trials
  
  Survival and functional outcome of stroke is strongly depending on the occurence of pneumonia (stroke-associated pneumonia, SAP). Early diagnose and treatment of SAP is paramount in the treatment of stroke patients. While dysphagia strongly contributes to its pathogenesis, recent years have also shown a strong risk-modulation by CNS injury induced immunosuppression, making stroke patients more susceptible to SAP. Additionally, murine models of stroke showed changes in mucociliary clearance as possible ...
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  Mentions: University of Lübeck
3. Artifacts in speckle tracking and multi-aperture Doppler OCT imaging of lateral motion
  
  Explore OSA | OSA Publishing Mar 16 2019
  
  In optical coherence tomography (OCT), lateral motion is determined either by speckle tracking or by multi-aperture Doppler OCT. Here we show that both methods may provide incorrect results because, outside the focal plane, non-uniform axial motion is misinterpreted as lateral motion. First, we demonstrate the existence of this artifact by means of a simulation for speckle tracking. Then the physical origin of the artifact and its mathematical relation to defocus ...
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  Mentions: Gereon Hüttmann University of Lübeck Hendrik Spahr
4. OptoRes presents world-record 3 MHz swept laser at SPIE BiOS / Photonics West in San Francisco
  
  Explore Optical Coherence Tomography News Jan 31 2019 Other Business News , Tunable Sources
  
  ...ength for high- quality OCT images. According to Prof. Robert Huber, Optores co-founder and professor at the Universität zu Lübeck, Optores’ core technology Fourier-domain mode-locking (FDML) plays a crucial role: “Opto...
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  Mentions: James G. Fujimoto Robert A. Huber University of Lübeck
5. Postdoc position, Intravital nanoscopy for investigating the blood-brain barrier (m/f/d)
  
  Explore Nature Publishing Group Jan 28 2019 Jobs & Studentships
  
  ...ed in the Small Animallmaging Lübeck (SAIL) facility in the Center for Brain, Behavior and Metabolism (CBBM), University of Lübeck. lt is based on a broad background in biomedical optics, intravital microscopy and cerebr...
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6. Optical coherence tomography provides an optical biopsy of burn wounds in children—a pilot study
  
  Explore SPIE Digital Library Oct 24 2018 Dermatology
  
  Thermic injuries are among the most severe injuries in childhood. Burn depth is the most relevant prognostic factor, and still its assessment is both difficult and controversial. This diagnostic uncertainty results in repeated wound assessments over a 10-day period and carries a relevant risk for over- and undertreatment. Precise wound assessment would thus be a significant step toward improved care. Optical coherence tomography (OCT) is a noninvasive laser-based technique with ...
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  Mentions: University of Lübeck Julia Welzel
7. Simple approach for aberration-corrected OCT imaging of the human retina
  
  Explore OSA | OSA Publishing Sep 7 2018 Ophthalmology
  
  Aberration-corrected imaging of human photoreceptor cells, whether hardware or software based, presently requires a complex and expensive setup. Here we use a simple and inexpensive off-axis full-field time-domain optical coherence tomography (OCT) approach to acquire volumetric data of an in vivo human retina. Full volumetric data are recorded in 1.3 s. After computationally correcting for aberrations, single photoreceptor cells were visualized. In addition, the numerical correction of ametropia is ...
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  Mentions: Gereon Hüttmann Reginald Birngruber University of Lübeck
8. High-speed fiber scanning endoscope for volumetric multi-megahertz optical coherence tomography
  
  Explore OSA | OSA Publishing Sep 6 2018 Probes
  
  We present a forward-viewing fiber scanning endoscope (FSE) for high-speed volumetric optical coherence tomography (OCT). The reduction in size of the probe was achieved by substituting the focusing optics by an all-fiber-based imaging system which consists of a combination of scanning single-mode fibers, a glass spacer, made from a step-index multi-mode fiber, and a gradient-index fiber. A lateral resolution of 11 m was achieved at a working distance of 1 ...
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  Mentions: Robert A. Huber Gereon Hüttmann University of Lübeck
9. Ultra low noise Fourier domain mode locked laser for high quality megahertz optical coherence tomography
  
  Explore OSA | OSA Publishing Aug 12 2018 Tunable Sources
  
  We investigate the origin of high frequency noise in Fourier domain mode locked (FDML) lasers and present an extremely well dispersion compensated setup which virtually eliminates intensity noise and dramatically improves coherence properties. We show optical coherence tomography (OCT) imaging at 3.2 MHz A-scan rate and demonstrate the positive impact of the described improvements on the image quality. Especially in highly scattering samples, at specular reflections and for strong ...
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  Mentions: Robert A. Huber University of Lübeck Technical University of Munich
10. Interferometric detection of 3D motion using computational subapertures in optical coherence tomography
  
  Explore OSA | OSA Publishing Jul 14 2018
  
  Doppler optical coherence tomography (OCT) quantifies axial motion with high precision, whereas lateral motion cannot be detected by a mere evaluation of phase changes. This problem was solved by the introduction of three-beam Doppler OCT, which, however, entails a high experimental effort. Here, we present the numerical analogue to this experimental approach. Phase-stable complex-valued OCT datasets, recorded with full-field swept-source OCT, are filtered in the Fourier domain to limit imaging ...
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  Mentions: Thorlabs Gereon Hüttmann University of Lübeck
11. Impact of correct anatomical slab segmentation on foveal avascular zone measurements by optical coherence tomography angiography in healthy adults
  
  Explore ScienceDirect Mar 24 2018 Ophthalmology
  
  urpose To evaluate the impact of correct anatomical slab segmentation on foveal avascular zone (FAZ) dimensions in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) using optical coherence tomography angiography (OCTA). Methods Participants with healthy retinas were recruited, and 5 5 mm OCTA images were acquired using the Canon HS-100 Angio eXpert module. FAZ size was measured in automatically (AS, manufacturer-based) and manually (MS, anatomical-based) segmented OCTA slabs ...
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  Mentions: University of Lübeck
12. Novel endoscope with increased depth of field for imaging human nasal tissue by microscopic optical coherence tomography
  
  Explore OSA | OSA Publishing Jan 21 2018 Otolaryngology , Probes
  
  Intravital microscopy (IVM) offers the opportunity to visualize static and dynamic changes of tissue on a cellular level. It is a valuable tool in research and may considerably improve clinical diagnosis. In contrast to confocal and non-linear microscopy, optical coherence tomography (OCT) with microscopic resolution (mOCT) provides intrinsically cross-sectional imaging. Changing focus position is not needed, which simplifies especially endoscopic imaging. For in-vivo imaging, here we are presenting endo-microscopic OCT ...
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  Mentions: Gereon Hüttmann University of Lübeck
13. High-resolution retinal swept source optical coherence tomography with an ultra-wideband Fourier-domain mode-locked laser at MHz A-scan rates
  
  Explore OSA | OSA Publishing Dec 9 2017 Ophthalmology , Tunable Sources
  
  We present a new 1060 nm Fourier domain mode locked laser (FDML laser) with a record 143 nm sweep bandwidth at 2∙ 417 kHz = 834 kHz and 120 nm at 1.67 MHz, respectively. We show that not only the bandwidth alone, but also the shape of the spectrum is critical for the resulting axial resolution, because of the specific wavelength-dependent absorption of the vitreous. The theoretical limit of our ...
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  Mentions: Robert A. Huber University of Lübeck Tom Pfeiffer
14. Retinal pulse wave velocity measurement using spectral-domain optical coherence tomography
  
  Explore Wiley Online Library Dec 9 2017
  
  In their latest publication on retinal pulse wave velocity measurement using optical co-herence tomography (OCT), Qian Li et al. propose a method to determine the pulse wave velocity in retinal arteries and veins [1]. This should enable a non-invasive determination of biomechanical properties of the vessel network, particularly the elasticity of the vessel walls [2].
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  Mentions: Gereon Hüttmann University of Lübeck Qian Li
15. Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography
  
  Explore IOVS Journal Nov 19 2017
  
  Purpose : Corneal neovascularization, in particular lymphangiogenesis, is a limiting factor in corneal transplant survival. Novel treatment approaches focus on (selective) inhibition and regression of lymphatic vessels. Imaging clinically invisible corneal lymphatic vessels is a prerequisite for these strategies. Using a murine model, this study investigates whether corneal lymphatic vessels can be imaged using microscopic optical coherence tomography (mOCT). Methods : Corneal neovascularization was induced by intrastromal placement of 11.0 nylon ...
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  Mentions: University of Cologne Gereon Hüttmann University of Lübeck
16. Feature Of The Week 09/10/2017: Thermo-elastic Optical Coherence Tomography
  
  Explore Optical Coherence Tomography News Sep 9 2017
  
  The conventional OCT image contrast is derived from elastic scattering, and shows the internal structure of the sample. The determination of the tissue type in OCT images usually depends on the interpretation by the image reader. More accurate tissue type contrast may be achieved by new OCT-based imaging modalities, with sensitivity to other physical parameters than scattering alone. Phase-sensitive OCT can detect tissue motion on nanometer-to- micrometer length scales using ...
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  Mentions: Robert A. Huber Delft University of Technology Chinese Academy of Sciences
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