Articles that mention University of Lübeck -Optical Coherence Tomography News

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1. Mentioned In 117 Articles
2. Dynamic contrast in scanning microscopic OCT
  
  Explore arxiv.org Mar 4 2020
  
  While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By evaluating signal fluctuations, a significant contrast enhancement was demonstrated using time-domain full-field OCT (FF-OCT), which makes cellular and subcellular structures visible. The putative cause of the dynamic OCT signal is ATP-dependent motion of cellular structures in a sub-micrometer range, which provides histology-like contrast ...
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  Mentions: Columbia University Gereon Hüttmann University of Lübeck
3. Intravital microscopic optical coherence tomography imaging to assess mucus mobilizing interventions for muco-obstructive lung disease in mice
  
  Explore American Physiological Society Journal Feb 4 2020 Pulmonology
  
  Airway mucus obstruction is a hallmark of chronic lung diseases such as cystic fibrosis, asthma and COPD, and the development of more effective mucus mobilizing therapies remains an important unmet need for patients with these muco-obstructive lung diseases. However, methods for sensitive visualization and quantitative assessment of immediate effects of therapeutic interventions on mucus clearance in vivo are lacking. In this study, we determined if newly developed high-speed microscopic optical ...
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  Mentions: Gereon Hüttmann University of Lübeck
4. Segmentation of Retinal Low-Cost Optical Coherence Tomography Images using Deep Learning
  
  Explore arxiv.org Jan 28 2020 Ophthalmology
  
  The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCTbased biomarkers. Therefore, the monitoring frequency has a significant influence on the success of AMD therapy. However, the monitoring frequency of current treatment schemes is not individually adapted to the patient and therefore often insufficient. While a higher monitoring frequency would ...
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  Mentions: Gereon Hüttmann University of Lübeck
5. Vessel Density in Glaucoma of Different Entities as Measured with Optical Coherence Tomography ...
  
  Explore Medical Journals Publisher Dec 17 2019 Ophthalmology
  
  ...45, Germany; 2Department of Ophthalmology, University of Essen, Essen, Germany; 3Department of Ophthalmology, University of Luebeck, Luebeck, Germany Correspondence: C Lommatzsch Department of Ophthalmology, St. Franzisk...
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  Mentions: University of Lübeck
6. Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography
  
  Explore Wiley Online Library Nov 26 2019 Dermatology
  
  Background/Objectives: Standard optical coherence tomography angiography (OCTA) has been limited to imaging blood vessels actively undergoing perfusion, providing a temporary picture of surface microvasculature. Capillary perfusion in the skin is dynamic and changes in response to the surrounding tissue's respiratory, nutritional, and thermoregulatory needs. Hence, OCTA often represents a given perfusion state without depicting the actual extent of the vascular network. Here we present a method for obtaining ...
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  Mentions: Massachusetts General Hospital Gereon Hüttmann Reginald Birngruber
7. Investigation of cell dynamics in 3D cell spheroids and cell interaction with 3D printed scaffolds by mOCT
  
  Explore Infinite Science Publishing Nov 21 2019 NDE/NDT
  
  Optical coherence tomography is a non-invasive and label-free imaging modality based on the detection of backscattered light in samples. As microscopic OCT (mOCT) combines high axial and lateral resolution, an investigation of biological and printed samples at subcellular level is feasible. The additional excellent depth resolution enables mOCT to be a suitable quality control of 3D printed samples. The use of speckle variance adds information about cell viability. Here we ...
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  Mentions: Gereon Hüttmann University of Lübeck
8. Simultaneous morphological and flow imaging enabled by megahertz intravascular Doppler optical coherence tomography
  
  Explore IEEE Xplore Nov 14 2019 Cardiology
  
  We demonstrate three-dimensional intravascular flow imaging compatible with routine clinical image acquisition workflow by means of megahertz (MHz) intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized imaging catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. Using a post processing method to compensate the drift of the FDML laser output, we can resolve the Doppler phase shift between ...
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  Mentions: Robert A. Huber Gijs van Soest Anton F. W. van der Steen
9. Notal Vision Announces Appointment of Dr. Kester Nahen as Chief Executive Officer
  
  Explore Optical Coherence Tomography News Oct 24 2019 Ophthalmology , Other Business News
  
  ...aserscope at 45% over market cap, at a price of $715 million. He received his PhD in Physics from the Medical University of Lübeck, Germany. Dr. Kester Nahen has repeatedly demonstrated effective leadership in high perf...
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  Mentions: University of Lübeck Kester Nahen Notal Vision
10. Reduction of periodic noise in Fourier domain optical coherence tomography images by frequency domain filtering
  
  Explore Home Sep 1 2019
  
  In Fourier domain optical coherence tomography (FDOCT) coherence noise is caused by interference of light waves back-reflected or scattered from different spots within a measuring depth or from optical components within the OCT system such as a bended optical fibre. This coherence noise appears as periodic stripe patterns along the axial direction in resulting images. Background subtraction and physical segmentation are used to degrade the periodic coherence noise in previous ...
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  Mentions: University of Freiburg University of Lübeck
11. Dr. Kester Nahen joins Notal Vision as Chief Commercial Officer
  
  Explore GlobeNewswire, Inc. Aug 8 2019 Ophthalmology , Other Business News
  
  ...ng Laserscope 45% over market cap at a price of $715 million. He received his PhD in Physics from the Medical University of Lübeck, Germany. Dr. Kester Nahen has repeatedly demonstrated effective leadership in cross-func...
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  Mentions: University of Lübeck Kester Nahen Notal Vision
12. Computational adaptive optics for optical coherence tomography using multiple randomized subaperture correlations
  
  Explore OSA | OSA Publishing Aug 1 2019
  
  Computational adaptive optics (CAO) is emerging as a viable alternative to hardware-based adaptive opticsin particular when applied to optical coherence tomography of the retina. For this technique, algorithms are required that detect wavefront errors precisely and quickly. Here we propose an extension of the frequently used subaperture image correlation. By applying this algorithm iteratively and, more importantly, comparing each subaperture not to the central subaperture but to several randomly selected ...
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  Mentions: Gereon Hüttmann University of Lübeck Hendrik Spahr
13. Motorized capsule for shadow-free OCT imaging and synchronous beam control
  
  Explore OSA | OSA Publishing Jul 19 2019 Gastroenterology , Probes
  
  We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments ...
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  Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University
14. Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks
  
  Explore OSA | OSA Publishing Jun 26 2019 Dermatology
  
  Optical coherence tomography (OCT) enables the non-invasive acquisition of high-resolution three-dimensional cross-sectional images at micrometer scale and is mainly used in the field of ophthalmology for diagnosis as well as monitoring of eye diseases. Also in other areas, such as dermatology, OCT is already well established. Due to its non-invasive nature, OCT is also employed for research studies involving animal models. Manual evaluation of OCT images of animal models is ...
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  Mentions: Massachusetts General Hospital Gereon Hüttmann University of Lübeck
15. Evaluating diurnal changes in choroidal sublayer perfusion using optical coherence tomography angiography
  
  Explore Wiley Online Library May 23 2019 Ophthalmology
  
  Purpose To investigate diurnal changes of choroidal sublayer perfusion in normal eyes and to identify influencing factors using optical coherence tomography angiography (OCTA). Methods A prospective study was conducted on healthy volunteers, each of whom underwent repeated measurements of subfoveal choroidal thickness (SFCT) via enhanced depth imaging (EDI) optical coherence tomography (OCT) as well as perfusion of choroidal vascular sublayers using OCTA at 7 a.m., 12 p.m., 4 ...
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  Mentions: University of Lübeck
16. Retinal perfusion 6 months after trabeculectomy as measured by optical coherence tomography angiography
  
  Explore Home - Springer May 16 2019 Ophthalmology
  
  Purpose To investigate potential changes of vessel density (VD) at the optic nerve head (ONH) and the macula 6 months after trabeculectomy (TE). Methods In a prospective monocentric study, 19 eyes with open-angle glaucoma were treated with TE+MMC (mitomycin C). At four different time points multiple morphological papillary parameters were measured by OCT, and the ONH VD in the radial peripapillary capillary layer and the superficial and deep plexuses ...
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  Mentions: Optovue University of Lübeck
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