1. University of Kent

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    1. Mentioned In 222 Articles

    2. Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source

      Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source
      We report on the use of a single supercontinuum (SC) source for multimodal imaging. The 2-octave bandwidth (4752300 nm) makes the SC source suitable for optical coherence tomography (OCT) as well as for multispectral photoacoustic microscopy (MPAM). The IR band centered at 1310 nm is chosen for OCT to penetrate deeper into tissue with 8 mW average power on the sample. The 500840 nm band is used for MPAM. The ...
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    3. Q-switched based supercontinuum source towards low-cost ultra-high resolution optical coherence tomography

      Q-switched based supercontinuum source towards low-cost ultra-high resolution optical coherence tomography
      Supercontinuum (SC) light source is certainly one of the best option for ultra-high resolution optical coherence tomography (UHR-OCT). Over the last few years several demonstrations have been done for each commonly used wavelength range [1-2-3]. Nowadays, SC dedicated to UHR-OCT is a mature technology with turn-key commercially available system [4]. The new challenge to answer for SC source is the cost reduction one. In this study, we demonstrate that a ...
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    4. Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis

      Two optical coherence tomography systems detect topical gold nanoshells in hair follicles, sweat ducts and measure epidermis
      Optical coherence tomography (OCT) is an optical imaging technology that enables real time, high‐resolution, cross‐sectional and en face investigation of skin by detecting reflected broad‐spectrum near‐infrared light from tissue. OCT provides micron‐scale spatial resolution and millimeter‐scale depth of penetration [1]. Several commercial OCT systems with handheld probes targeted for Dermatology are now available [2].
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    5. PhD Scholarship: Multimodal optical coherence tomography / multi-spectral photo-acoustic imaging at University of Kent

      PhD Scholarship: Multimodal optical coherence tomography / multi-spectral photo-acoustic imaging at University of Kent
      ...ue is possible and reconstruct the chromophore concentrations. The successful candidate will be based at the University of Kent's main campus in Canterbury as part of the Applied Optics Group, in the School of Physical ...
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    6. In-vivo detection of the skin dermo-epidermal junction by ultrahigh resolution optical coherence tomography

      In-vivo detection of the skin dermo-epidermal junction by ultrahigh resolution optical coherence tomography
      The human skin is comprised by two layers; epidermis and dermis, separated by the dermo-epidermal junction (DEJ). The relevance of depicting DEJ and measurement of the epidermal thickness (ET) is e.g. seen for superficial skin cancers where delineation of DEJ is of prime prognostic importance. Another example is diagnosis of psoriasis where a thickened epidermis and a ridged DEJ is a hallmark. Histopathological examination of biopsied tissue is traditionally ...
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    7. Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

      Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm
      Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC ...
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    8. Two Optical Coherence Tomography Systems detect Topical Gold Nanoparticles in Hair follicles, Sweat Ducts and Measure Epidermis

      Two Optical Coherence Tomography Systems detect Topical Gold Nanoparticles in Hair follicles, Sweat Ducts and Measure Epidermis
      Optical coherence tomography (OCT) is an optical imaging technology that enables real time, highresolution, cross-sectional and en face investigation of skin by detecting reflected broad-spectrum near-infrared light from tissue. OCT provides micron-scale spatial resolution and millimeter-scale depth of penetration [1]. Several commercial OCT systems with handheld probes targeted for Dermatology are now available [2]. The ability of OCT to achieve high diagnostic accuracy in skin diseases is hampered by the ...
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    9. All-depth dispersion cancellation in spectral domain optical coherence tomography using numerical intensity correlations

      All-depth dispersion cancellation in spectral domain optical coherence tomography using numerical intensity correlations
      In ultra-high resolution (UHR-) optical coherence tomography (OCT) group velocity dispersion (GVD) must be corrected for in order to approach the theoretical resolution limit. One approach promises not only compensation, but complete annihilation of even order dispersion effects, and that at all sample depths. This approach has hitherto been demonstrated with an experimentally demanding balanced detection configuration based on using two detectors. We demonstrate intensity correlation (IC) OCT using a ...
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    10. Assessment of Ductile, Brittle, and Fatigue Fractures of Metals Using Optical Coherence Tomography

      Assessment of Ductile, Brittle, and Fatigue Fractures of Metals Using Optical Coherence Tomography
      ome forensic in situ investigations, such as those needed in transportation (for aviation, maritime, road, or rail accidents) or for parts working under harsh conditions (e.g., pipes or turbines) would benefit from a method/technique that distinguishes ductile from brittle fractures of metalsas material defects are one of the potential causes of incidents. Nowadays, the gold standard in material studies is represented by scanning electron microscopy (SEM). However, SEM ...
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    11. An overview of methods to mitigate artifacts in optical coherence tomography imaging of the skin

      An overview of methods to mitigate artifacts in optical coherence tomography imaging of the skin
      Background Optical coherence tomography (OCT) of skin delivers three-dimensional images of tissue microstructures. Although OCT imaging offers a promising high-resolution modality, OCT images suffer from some artifacts that lead to misinterpretation of tissue structures. Therefore, an overview of methods to mitigate artifacts in OCT imaging of the skin is of paramount importance. Speckle, intensity decay, and blurring are three major artifacts in OCT images. Speckle is due to the low ...
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    12. Q-switch-pumped supercontinuum for ultra-high resolution optical coherence tomography

      Q-switch-pumped supercontinuum for ultra-high resolution optical coherence tomography
      In this Letter, we investigate the possibility of using a commercially availableQ-switch-pumped supercontinuum (QS-SC) source, operating in the kilohertz regime, for ultra-high resolution optical coherence tomography (UHR-OCT) in the 1300nm region. The QS-SC source proves to be more intrinsically stable from pulse to pulse than a mode-locked-based SC (ML-SC) source while, at the same time, is less expensive. However, its pumping rate is lower than that used in ML-SC sources ...
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    13. Cystoid macular edema segmentation of Optical Coherence Tomography images using fully convolutional neural networks and fully connected CRFs

      Cystoid macular edema segmentation of Optical Coherence Tomography images using fully convolutional neural networks and fully connected CRFs
      In this paper we present a new method for cystoid macular edema (CME) segmentation in retinal Optical Coherence Tomography (OCT) images, using a fully convolutional neural network (FCN) and a fully connected conditional random fields (dense CRFs). As a first step, the framework trains the FCN model to extract features from retinal layers in OCT images, which exhibit CME, and then segments CME regions using the trained model. Thereafter, dense ...
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  2. About University of Kent

    University of Kent

    University of Kent is a UK higher education institution founded in 1965 and funded by the Higher Education Funding Council for England. There are campus at Cantebury (main campus), Medway, Brussels, Tonbridge, and Transmache.  The Applied Optics Group at the University of Kent school of physical sciences. Research areas include: Optical sensors, Optical fibre sensors, Medical sensors and imaging, Optical coherence tomography, Adaptive optics, Components for optical communications and sensors, Theory, Electro-optical, acousto-optical micro-structures, and Forensics.