1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 226 Articles

    2. Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography

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      Interstitial magnetic thermotherapy dosimetry based on shear wave magnetomotive optical coherence elastography
      While magnetic thermoseeds are often utilized in interstitial magnetic thermotherapy (iMT) to enable localized tumor ablation, we propose to extend their use as the perturbative source in magnetomotive optical coherence elastography (MM-OCE) so that the heat-induced elasticity alterations can be theranostically probed. MM-OCE measurements were found to agree with indentation results. Tissue stiffening was visualized on iMT-treated porcine liver and canine soft tissue sarcoma specimens, where histology confirmed thermal damages ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    3. Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications

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      Economical and compact briefcase spectral-domain optical coherence tomography system for primary care and point-of-care applications
      Development of low-cost and portable optical coherence tomography (OCT) systems is of global interest in the OCT research community. Such systems enable utility broadly throughout a clinical facility, or in remote areas that often lack clinical infrastructure. We report the development and validation of a low-cost, portable briefcase spectral-domain optical coherence tomography (SD-OCT) system for point-of-care diagnostics in primary care centers and/or in remote settings. The self-contained briefcase OCT ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Roshan Dsouza

    4. Intraoperative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography

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      Intraoperative imaging of surgical margins of canine soft tissue sarcoma using optical coherence tomography
      Optical coherence tomography (OCT) is a rapid non‐invasive imaging technique that has shown high sensitivity for intraoperative surgical margin assessment in human breast cancer clinical trials. This promising technology has not been evaluated in veterinary medicine. The objective of this study was to correlate normal and abnormal histological features with OCT images for surgical margins from excised canine soft tissue sarcoma (STS) and to establish image evaluation criteria for ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Marina Marjanovic

    5. Image Data Analyst, GlaxoSmithKline Center for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

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      Image Data Analyst, GlaxoSmithKline Center for Optical Molecular Imaging, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
      ...st GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign Solid and broad understanding of image analysis software as well as...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    6. Imaging Research Scientist, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign

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      Imaging Research Scientist, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
      ...ore about the Universitys commitment to diversity, please visit http://www.inclusiveillinois.illinois.edu The Biophotonics Imaging Laboratory and the Center for Optical Molecular Imaging at the Beckman Institute for Adva...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    7. Intraoperative breast cancer margin detection via polarization-sensitive optical coherence tomography

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      Intraoperative breast cancer margin detection via polarization-sensitive optical coherence tomography
      Current standard-of-care for breast conserving surgery (BCS) procedures relies on post-operative histopathology to provide a microscopic view and assessment of surgical margins. To avoid high reoperation rates there has been a great interest in developing new imaging solutions to visualize tissue intraoperatively, and provide real-time feedback on the margin status. Optical coherence tomography (OCT) is a high-resolution label-free, imaging technology that is the optical analogue to ultrasound imaging, except images ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    8. PhotoniCare Receives $2.1 Million National Institute of Health Phase IIb Small Business Innovation Research Award

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      PhotoniCare Receives $2.1 Million National Institute of Health Phase IIb Small Business Innovation Research Award
      ...t of Dr. Stephen Boppart’s Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign (UIUC), PhotoniCare continues its relationship with UIUC as an EnterpriseWorks incubator company. For more info...
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      Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign

    9. Magnetomotive Displacement of the Tympanic Membrane using Magnetic Nanoparticles: Toward Enhancement of Sound Perception

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      Magnetomotive Displacement of the Tympanic Membrane using Magnetic Nanoparticles: Toward Enhancement of Sound Perception
      Objective: A novel hearing-aid scheme using magnetomotive nanoparticles (MNPs) as transducers in the tympanic membrane (TM) is proposed, aiming to noninvasively and directly induce a modulated vibration on the TM. Methods: In this feasibility study, iron-oxide (Fesub3/subOsub4/sub) nanoparticles were applied on ex vivo rat TM tissues and allowed to diffuse over ~2 hr. Subsequently, magnetic force was exerted on the MNP-laden TM via a programmable electromagnetic solenoid to ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    10. Wavefront measurement using computational adaptive optics

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      Wavefront measurement using computational adaptive optics
      In many optical imaging applications, it is necessary to correct for aberrations to obtain high quality images. Optical coherence tomography (OCT) provides access to the amplitude and phase of the backscattered optical field for three-dimensional (3D) imaging samples. Computational adaptive optics (CAO) modifies the phase of the OCT data in the spatial frequency domain to correct optical aberrations without using a deformable mirror, as is commonly done in hardware-based adaptive ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign P. Scott Carney

    11. Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment

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      Label-free optical imaging technologies for rapid translation and use during intraoperative surgical and tumor margin assessment
      The biannual International Conference on Biophotonics was recently held on April 30 to May 1, 2017, in Fremantle, Western Australia. This continuing conference series brought together key opinion leaders in biophotonics to present their latest results and, importantly, to participate in discussions on the future of the field and what opportunities exist when we collectively work together for using biophotonics for biological discovery and medical applications. One session in this ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign University of Western Australia

    12. Review of optical coherence tomography in oncology

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      Review of optical coherence tomography in oncology
      The application of optical coherence tomography (OCT) in the field of oncology has been prospering over the past decade. OCT imaging has been used to image a broad spectrum of malignancies, including those arising in the breast, brain, bladder, the gastrointestinal, respiratory, and reproductive tracts, the skin, and oral cavity, among others. OCT imaging has initially been applied for guiding biopsies, for intraoperatively evaluating tumor margins and lymph nodes, and ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    13. Noninvasive in vivo optical coherence tomography tracking of chronic otitis media in pediatric subjects after surgical intervention

      Explore SPIE Digital Library Otolaryngology
      Noninvasive in vivo optical coherence tomography tracking of chronic otitis media in pediatric subjects after surgical intervention
      In an institutional review board-approved study, 25 pediatric subjects diagnosed with chronic or recurrent otitis media were observed over a period of six months with optical coherence tomography (OCT). Subjects were followed throughout their treatment at the initial patient evaluation and preoperative consultation, surgery (intraoperative imaging), and postoperative follow-up, followed by an additional six months of records-based observation. At each time point, the tympanic membrane (at the light reflex region ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    14. Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements

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      Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements
      Since the inception of optical coherence tomography (OCT), advancements in imaging system design and handheld probes have allowed for numerous advancements in disease diagnostics and characterization of the structural and optical properties of tissue. OCT system developers continue to reduce form factor and cost, while improving imaging performance (speed, resolution, etc.) and flexibility for applicability in a broad range of fields, and nearly every clinical specialty. An extensive array of ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Roshan Dsouza

    15. Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy

      Explore Wiley Online Library Dermatology
      Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy
      Impaired skin wound healing is a significant co-morbid condition of diabetes that is caused by poor microcirculation, among other factors. Studies have shown that angiogenesis, a critical step in the wound healing process in diabetic wounds, can be promoted under hypoxia. In this study, an angiogenesis-promoting topical treatment for diabetic wounds, which promotes angiogenesis by mimicking a hypoxic environment via inhibition of prolyl hydroxylase resulting in elevation or maintenance of ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    16. UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear
      ...and impact will be a new standard-of-care for the management of ear infections, with improved patient care

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $454,301 for Partnership for Primary ...

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      Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign
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  4. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.

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