1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 187 Articles

    2. Response of simulated drinking water biofilm mechanical and structural properties to long-term disinfectant exposure

      Response of simulated drinking water biofilm mechanical and structural properties to long-term disinfectant exposure
      Mechanical and structural properties of biofilms influence the accumulation and release of pathogens in drinking water distribution systems (DWDS). Thus, understanding how long-term residual disinfectants exposure affects biofilm mechanical and structural properties is a necessary aspect for pathogen risk assessment and control. In this study, elastic modulus and structure of groundwater biofilms was monitored by atomic force microscopy (AFM) and optical coherence tomography (OCT) during three months of exposure to ...
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    3. IMAGING WITH MULTIMODAL ADAPTIVE-OPTICS OPTICAL COHERENCE TOMOGRAPHY IN MULTIPLE EVANESCENT WHITE DOT SYNDROME: THE STRUCTURE AND FUNCTIONAL RELATIONSHIP

      IMAGING WITH MULTIMODAL ADAPTIVE-OPTICS OPTICAL COHERENCE TOMOGRAPHY IN MULTIPLE EVANESCENT WHITE DOT SYNDROME: THE STRUCTURE AND FUNCTIONAL RELATIONSHIP
      Purpose: To elucidate the location of pathological changes in multiple evanescent white dot syndrome (MEWDS) with the use of multimodal adaptive optics (AO) imaging . Methods: A 5-year observational case study of a 24-year-old female with recurrent MEWDS. Full examination included history, Snellen chart visual acuity, pupil assessment, intraocular pressures, slit lamp evaluation, dilated fundoscopic exam, imaging with Fourier-domain optical coherence tomography (FD-OCT), blue-light fundus autofluorescence (FAF), fundus photography, fluorescein angiography ...
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    4. Polarization-sensitive interferometric synthetic aperture microscopy

      Polarization-sensitive interferometric synthetic aperture microscopy
      Three-dimensional optical microscopy suffers from the well-known compromise between transverse resolution and depth-of-field. This is true for both structural imaging methods and their functional extensions. Interferometric synthetic aperture microscopy (ISAM) is a solution to the 3D coherent microscopy inverse problem that provides depth-independent transverse resolution. We demonstrate the extension of ISAM to polarization sensitive imaging, termed polarization-sensitive interferometric synthetic aperture microscopy (PS-ISAM). This technique is the first functionalization of the ...
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    5. Flashlight-Sized Probe Can Spot Cancer Cells in Real Time

      Flashlight-Sized Probe Can Spot Cancer Cells in Real Time
      Malignant tumor strongholds and their microscopic spies cant hide in the thicket of flesh much longer, for surgeons have a new weapon: a device that sheds light on their location. Literally. Any state of disease will alter the cells and molecules in our body, said Dr. Stephen Boppart, a professor of bioengineering at the University of Illinois who invented the device. Every molecule scatters light different ways, he said, leaving ...
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    6. Indentation Measurements to Validate Dynamic Elasticity Imaging Methods

      Indentation Measurements to Validate Dynamic Elasticity Imaging Methods
      We describe macro-indentation techniques for estimating the elastic modulus of soft hydrogels. Our study describes (a) conditions under which quasi-static indentation can validate dynamic shear-wave imaging estimates and (b) how each of these techniques uniquely biases modulus estimates as they couple to the sample geometry. Harmonic shear waves between 25 and 400 Hz were imaged using ultrasonic Doppler and optical coherence tomography methods to estimate shear dispersion. From the shear-wave ...
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    7. Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery

      Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery
      Wide local excision (WLE) is a common surgical intervention for solid tumors such as those in melanoma, breast, pancreatic, and gastrointestinal cancer. However, adequate margin assessment during WLE remains a significant challenge, resulting in surgical reinterventions to achieve adequate local control. Currently, no label-free imaging method is available for surgeons to examine the resection bed in vivo for microscopic residual cancer. Optical coherence tomography (OCT) enables real-time high-resolution imaging of ...
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    8. Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma

      Retinal imaging with en face and cross-sectional optical coherence tomography delineates outer retinal changes in cancer-associated retinopathy secondary to Merkel cell carcinoma
      Background The study aims to correlate Fourier-domain optical coherence tomography (FD-OCT) with Goldmann visual field (GVF) to show the photoreceptor (PR) structure and function relationship in the first described case of cancer-associated retinopathy (CAR) from Merkel cell carcinoma. Findings A case study of a patient with CAR who was imaged with serial GVF and FD-OCT over a 2-year period was carried out. En face images were created using a custom ...
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    9. Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud

      Intraoperative Assessment of Final Margins with a Handheld Optical Imaging Probe During Breast-Conserving Surgery May Reduce the Reoperation Rate: Results of a Multicenter Stud
      Background A multicenter, prospective, blinded study was performed to test the feasibility of using a handheld optical imaging probe for the intraoperative assessment of final surgical margins during breast-conserving surgery (BCS) and to determine the potential impact on patient outcomes. Methods Forty-six patients with early-stage breast cancer (one with bilateral disease) undergoing BCS at two study sites, the Johns Hopkins Hospital and Anne Arundel Medical Center, were enrolled in this ...
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    10. UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging

      UIUC Receives a NIH Grant for a Partnership for Primary Care Imaging
      University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $925,920 for a Partnership for Primary Care Imaging. The principal investigaror is Stephen Boppart. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Primary Care Medicine, including Family Practice and Pediatrics, has traditionally relied on physical exam skills and simplistic instruments for critical diagnostic decision making, monitoring, and referral to medical ...
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    11. Computational high-resolution optical imaging of the living human retina

      Computational high-resolution optical imaging of the living human retina
      High-resolution in vivo imaging is of great importance for the fields of biology and medicine. The introduction of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-resolution near diffraction-limited imaging of previously unresolvable structures 1 , 2 . In ophthalmology, when combined with optical coherence tomography, HAO has enabled a detailed three-dimensional visualization of photoreceptor distributions 3 , 4 and individual nerve fibre bundles 5 in the living human ...
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    12. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives NIH Grant  for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.
      The University of Illinois Urbana-Champaign Receives a 2015 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program begain in 2012 and ends in 2017. Below is a summary of the proosed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving ...
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    13. New technology looks into the eye and brings cells into focus

      New technology looks into the eye and brings cells into focus
      Eye doctors soon could use computing power to help them see individual cells in the back of a patients eye, thanks to imaging technology developed by engineers at the University of Illinois. Such detailed pictures of the cells, blood vessels and nerves at the back of the eye could enable earlier diagnosis and better treatment for degenerative eye and neurological diseases. New technology uses computational techniques to more clearly see ...
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    14. 1-15 of 187 1 2 3 4 ... 11 12 13 »
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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.