1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 212 Articles

    2. UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      UIUC Receives a NIH Grant for Partnership for Primary Care Imaging of the Ear
      ...and impact will be a new standard-of-care for the management of ear infections, with improved patient care

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $454,301 for Partnership for Primary ...

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      Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign

    3. Ratiometric analysis of optical coherence tomography–measured in vivo retinal layer thicknesses for the detection of early diabetic retinopathy

      Explore Wiley Online Library Ophthalmology
      Ratiometric analysis of optical coherence tomography–measured in vivo retinal layer thicknesses for the detection of early diabetic retinopathy
      Influence of diabetes mellitus (DM) and diabetic retinopathy (DR) on parafoveal retinal thicknesses and their ratios was evaluated. Six retinal layer boundaries were segmented from spectral-domain optical coherence tomography images using open-source software. Five study groups: (1) healthy control (HC) subjects, and subjects with (2) controlled DM, (3) uncontrolled DM, (4) controlled DR and (5) uncontrolled DR, were identified. The one-way analyses of variance (ANOVA) between adjacent study groups (i ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    4. Introduction to the feature issue on the 25 year anniversary of optical coherence tomography

      Explore OSA | OSA Publishing
      Introduction to the feature issue on the 25 year anniversary of optical coherence tomography
      This feature issue commemorates the approximately 25 year history of Optical Coherence Tomography (OCT), one of the most successful biophotonic technologies. While OCT has technological origins traceable to ultrafast laser development and fiber optic system test instrumentation of the 1980s, innovations in low coherence interferometry for optical ranging and imaging for biomedical applications in the U.S., Europe and Japan by the early 1990s led to coinage of the now ...
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      Mentions: Brett E. Bouma Johannes F. de Boer Joseph A. Izatt

    5. Smart phone attachment for 3-D optical coherence tomography imaging

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      Smart phone attachment for 3-D optical coherence tomography imaging
      Methods and apparatus for tomographic imaging of a sample. Low-coherence light is split into a sample path and a reference path. A steering optic recombines light in the reference path with light scattered by a sample onto a camera having an areal focal plane array of detector elements such that light in the reference path and light scattered by the sample are characterized by respectively offset propagation vectors at incidence ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    6. Intraoperative optical coherence tomography for soft tissue sarcoma differentiation and margin identification

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      Intraoperative optical coherence tomography for soft tissue sarcoma differentiation and margin identification
      Background and Objective Sarcomas are rare but highly aggressive tumors, and local recurrence after surgical excision can occur in up to 50% cases. Therefore, there is a strong clinical need for accurate tissue differentiation and margin assessment to reduce incomplete resection and local recurrence. The purpose of this study was to investigate the use of optical coherence tomography (OCT) and a novel image texture-based processing algorithm to differentiate sarcoma from ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    7. Quantitative characterization of mechanically indented in vivo human skin in adults and infants using optical coherence tomography

      Explore SPIE | Journal Dermatology
      Quantitative characterization of mechanically indented in vivo human skin in adults and infants using optical coherence tomography
      Influenced by both the intrinsic viscoelasticity of the tissue constituents and the time-evolved redistribution of fluid within the tissue, the biomechanical response of skin can reflect not only localized pathology but also systemic physiology of an individual. While clinical diagnosis of skin pathologies typically relies on visual inspection and manual palpation, a more objective and quantitative approach for tissue characterization is highly desirable. Optical coherence tomography (OCT) is an interferometry-based ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    8. In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe

      Explore OSA | OSA Publishing Otolaryngology , Probes
      In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe
      A wide-field optical coherence tomography (OCT) probe was developed that adapts a diagonal-scanning scheme for three-dimensional (3D) in vivo imaging of the human tympanic membrane. The probe consists of a relay lens to enhance the lateral scanning range up to 7 mm. Motion artifacts that occur with the use of handheld probes were found to be decreased owing to the diagonal-scanning pattern, which crosses the center of the sample to ...
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      Mentions: Stephen A. Boppart Harvard University University of Illinois at Urbana-Champaign

    9. Computational optical coherence tomography [Invited]

      Explore OSA | OSA Publishing
      Computational optical coherence tomography [Invited]
      Optical coherence tomography (OCT) has become an important imaging modality with numerous biomedical applications. Challenges in high-speed, high-resolution, volumetric OCT imaging include managing dispersion, the trade-off between transverse resolution and depth-of-field, and correcting optical aberrations that are present in both the system and sample. Physics-based computational imaging techniques have proven to provide solutions to these limitations. This review aims to outline these computational imaging techniques within a general mathematical framework ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign P. Scott Carney

    10. Low-cost hand-held probe for depth-resolved low-coherence interferometry

      Explore OSA | OSA Publishing Otolaryngology , Probes
      Low-cost hand-held probe for depth-resolved low-coherence interferometry
      We report on the development of a low-cost hand-held low-coherence interferometric imaging system based on the principle of linear optical coherence tomography (Linear OCT), a technique which was first proposed in the early 2000s as a simpler alternative to the conventional time-domain and Fourier-domain OCT. A bench-top implementation of the proposed technique is first presented and validated. The axial resolution, SNR, and sensitivity roll-of of the system was estimated to ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    12. UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      Explore Optical Coherence Tomography News Oncology , Funding
      UIUC Receives a NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins
      ...acceptably high reoperation rates in the surgical treatment of breast cancer.

      University of Illinois at Urbana-Champaign Receives a 2017 NIH Grant for $548,714 for Intraoperative Polarizat...

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      Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign

    13. Inverse scattering for frequency-scanned full-field optical coherence tomography

      Explore OSA | OSA Publishing
      Inverse scattering for frequency-scanned full-field optical coherence tomography
      Full-field optical coherence tomography (OCT) is able to image an entire en face plane of scatterers simultaneously, but typically the focus is scanned through the volume to acquire three-dimensional structure. By solving the inverse scattering problem for full-field OCT, we show it is possible to computationally reconstruct a three-dimensional volume while the focus is fixed at one plane inside the sample. While a low-numerical-aperture (NA) OCT system can tolerate defocus ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Tyler S. Ralston

    15. A Mosaicking Approach for In Vivo Thickness Mapping of the Human Tympanic Membrane Using Low Coherence Interferometry

      Explore Home - Springer Otolaryngology
      A Mosaicking Approach for In Vivo Thickness Mapping of the Human Tympanic Membrane Using Low Coherence Interferometry
      The thickness of the human tympanic membrane (TM) is known to vary considerably across different regions of the TM. Quantitative determination of the thickness distribution and mapping of the TM is of significant importance in hearing research, particularly in mathematical modeling of middle-ear dynamics. Change in TM thickness is also associated with several middle-ear pathologies. Determination of the TM thickness distribution could therefore also enable a more comprehensive diagnosis of ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    16. Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range

      Explore OSA | OSA Publishing
      Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range
      ...ois at Urbana-Champaign, 201 North Goodwin Avenue, Urbana, Illinois 61801, USA 5Department of Bioengineering, University of Illinois at Urbana-Champaign, 1304 West Springfield Avenue, Urbana, Illinois 61801, USA *Corresp...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign P. Scott Carney
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  4. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.

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