1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 201 Articles

    2. Inverse scattering for frequency-scanned full-field optical coherence tomography

      Inverse scattering for frequency-scanned full-field optical coherence tomography
      Full-field optical coherence tomography (OCT) is able to image an entire en face plane of scatterers simultaneously, but typically the focus is scanned through the volume to acquire three-dimensional structure. By solving the inverse scattering problem for full-field OCT, we show it is possible to computationally reconstruct a three-dimensional volume while the focus is fixed at one plane inside the sample. While a low-numerical-aperture (NA) OCT system can tolerate defocus ...
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    3. A Mosaicking Approach for In Vivo Thickness Mapping of the Human Tympanic Membrane Using Low Coherence Interferometry

      A Mosaicking Approach for In Vivo Thickness Mapping of the Human Tympanic Membrane Using Low Coherence Interferometry
      The thickness of the human tympanic membrane (TM) is known to vary considerably across different regions of the TM. Quantitative determination of the thickness distribution and mapping of the TM is of significant importance in hearing research, particularly in mathematical modeling of middle-ear dynamics. Change in TM thickness is also associated with several middle-ear pathologies. Determination of the TM thickness distribution could therefore also enable a more comprehensive diagnosis of ...
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    4. Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range

      Filtering for unwrapping noisy Doppler optical coherence tomography images for extended microscopic fluid velocity measurement range
      ...ois at Urbana-Champaign, 201 North Goodwin Avenue, Urbana, Illinois 61801, USA 5Department of Bioengineering, University of Illinois at Urbana-Champaign, 1304 West Springfield Avenue, Urbana, Illinois 61801, USA *Corresp...
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    5. Automated computational aberration correction method for broadband interferometric imaging techniques

      Automated computational aberration correction method for broadband interferometric imaging techniques
      Numerical correction of optical aberrations provides an inexpensive and simpler alternative to the traditionally used hardware-based adaptive optics techniques. In this Letter, we present an automated computational aberration correction method for broadband interferometric imaging techniques. In the proposed method, the process of aberration correction is modeled as a filtering operation on the aberrant image using a phase filter in the Fourier domain. The phase filter is expressed as a linear ...
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    6. Swept Source Optical Coherence Tomography Imaging of the Middle Ear Cavity (Thesis)

      Swept Source Optical Coherence Tomography Imaging of the Middle Ear Cavity (Thesis)
      Otitis media (OM), a bacterial infection of the middle ear, is a common pediatric disease. Chronic and recurrent OM is often treated with the surgical placement of tympanostomy tubes in the tympanic membrane (TM), which is the most common reason for pediatric surgery and anesthesia. Antibiotic treatment for chronic OM (COM) is often ineffective, which is explained by the hypothesis that OM is a biofilm-related disease. Recent studies in humans ...
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    7. UIUC Receives NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.

      UIUC Receives  NIH Grant for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins.
      University of Illionois at Urbana-Champaign Receives a 2016 NIH Grant for $490,333 for Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins. The principal investiagator is Stephen Boppart. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving ...
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    8. Detection of retinal blood vessel changes in multiple sclerosis with optical coherence tomography

      Detection of retinal blood vessel changes in multiple sclerosis with optical coherence tomography
      Although retinal vasculitis is common in multiple sclerosis (MS), it is not known if MS is associated with quantitative abnormalities in retinal blood vessels (BVs). Optical coherence tomography (OCT) is suitable for examining the integrity of the anterior visual pathways in MS. In this paper we have compared the size and number of retinal blood vessels in patients with MS, with and without a history of optic neuritis (ON), and ...
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    9. Non-invasive optical assessment of viscosity of middle ear effusions in otitis media

      Non-invasive optical assessment of viscosity of middle ear effusions in otitis media
      In vivo Optical Coherence Tomography (OCT) image of a human tympanic membrane and Middle Ear Effusion (MEE) (top), with a CCD image of the tympanic membrane surface (inset). Below is the corresponding time-lapse M-mode OCT data acquired along the white dotted line over time, which can be analyzed to determine the StokesEinstein diffusion coefficient of the effusion. Eustachian tube dysfunction can cause fluid to collect within the middle ear cavity ...
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    10. Computational adaptive optics of the human retina

      Computational adaptive optics of the human retina
      It is well known that patient-specific ocular aberrations limit imaging resolution in the human retina. Previously, hardware adaptive optics (HAO) has been employed to measure and correct these aberrations to acquire high-resolution images of various retinal structures. While the resulting aberration-corrected images are of great clinical importance, clinical use of HAO has not been widespread due to the cost and complexity of these systems. We present a technique termed computational ...
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    11. Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography

      Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography
      ...gn, 405 North Mathews Avenue, Urbana, Illinois 61801, USA 2Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, 306 North Wright Street, Urbana, Illinois 61801, USA 3Department o...
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    12. Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer

      Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer
      Background Evaluation of lymph node (LN) status is an important factor for detecting metastasis and thereby staging breast cancer. Currently utilized clinical techniques involve the surgical disruption and resection of lymphatic structure, whether nodes or axillary contents, for histological examination. While reasonably effective at detection of macrometastasis , the majority of the resected lymph nodes are histologically negative. Improvements need to be made to better detect micrometastasis , minimize or eliminate lymphatic ...
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    13. Response of simulated drinking water biofilm mechanical and structural properties to long-term disinfectant exposure

      Response of simulated drinking water biofilm mechanical and structural properties to long-term disinfectant exposure
      Mechanical and structural properties of biofilms influence the accumulation and release of pathogens in drinking water distribution systems (DWDS). Thus, understanding how long-term residual disinfectants exposure affects biofilm mechanical and structural properties is a necessary aspect for pathogen risk assessment and control. In this study, elastic modulus and structure of groundwater biofilms was monitored by atomic force microscopy (AFM) and optical coherence tomography (OCT) during three months of exposure to ...
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    14. 1-15 of 201 1 2 3 4 ... 12 13 14 »
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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.