1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 252 Articles

    2. Statistical evaluation of reader variability in assessing the diagnostic performance of optical coherence tomography

      Explore SPIE Digital Library Oncology
      Statistical evaluation of reader variability in assessing the diagnostic performance of optical coherence tomography
      Significance: Optical coherence tomography (OCT) is widely used as a potential diagnostic tool for a variety of diseases including various types of cancer. However, sensitivity and specificity analyses of OCT in different cancers yield results varying from 11% to 100%. Hence, there is a need for more detailed statistical analysis of blinded reader studies. Aim: Extensive statistical analysis is performed on results from a blinded study involving OCT of breast ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    3. The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors

      Explore Wiley Online Library Oncology
      The feasibility and utility of optical coherence tomography directed histopathology for surgical margin assessment of canine mast cell tumors
      Histopathologic surgical margin assessment in veterinary patients is an imprecise science with assessment limited to a small proportion of the surgical margin due to time and finances. Incomplete excision of canine mast cell tumors (MCTs) alters treatment recommendations and prognosis. Optical coherence tomography (OCT) is a novel imaging modality that has been reported in a single veterinary study for surgical margin assessment. Twenty‐five dogs with 34 MCTs were enrolled ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign The Ohio State University

    4. Suspended scattering particles in motion using OCT angiography in branch retinal vein occlusion disease cases with cystoid macular edema

      Explore Nature Publishing Group Ophthalmology
      Suspended scattering particles in motion using OCT angiography in branch retinal vein occlusion disease cases with cystoid macular edema
      We aimed to investigate the clinical implication of suspended scattering particles in motion (SSPiM) using optical coherence tomography angiography (OCTA) among branch retinal vein occlusion disease (BRVO) cases with macular edema (ME). Medical records of BRVO patients were reviewed. Central retinal thickness (CRT), ME type, and cyst size on optical coherence tomography images were evaluated before and after intravitreal bevacizumab injection. Nonperfusion area, SSPiM, and microvascular abnormalities in OCTA images ...
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      Mentions: University of Illinois at Urbana-Champaign

    6. Automated fast computational adaptive optics for optical coherence tomography based on a stochastic parallel gradient descent algorithm

      Explore OSA | OSA Publishing
      Automated fast computational adaptive optics for optical coherence tomography based on a stochastic parallel gradient descent algorithm
      The transverse resolution of optical coherence tomography is decreased by aberrations introduced from optical components and the tested samples. In this paper, an automated fast computational aberration correction method based on a stochastic parallel gradient descent (SPGD) algorithm is proposed for aberration-corrected imaging without adopting extra adaptive optics hardware components. A virtual phase filter constructed through combination of Zernike polynomials is adopted to eliminate the wavefront aberration, and their coefficients ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Dan Zhu

    7. Single-shot two-dimensional spectroscopic magnetomotive optical coherence elastography with graphics processing unit acceleration

      Explore OSA | OSA Publishing
      Single-shot two-dimensional spectroscopic magnetomotive optical coherence elastography with graphics processing unit acceleration
      Biomechanical contrast within tissues can be assessed based on the resonant frequency probed by spectroscopic magnetomotive optical coherence elastography (MM-OCE). However, to date, in vivo MM-OCE imaging has not been achieved, mainly due to the constraints on imaging speed. Previously, spatially-resolved spectroscopic contrast was achieved in a multiple-excitation, multiple-acquisition manner, where seconds of coil cooling time set between consecutive imaging frames lead to total acquisition times of tens of minutes ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    8. Optical coherence tomography imaging of excised canine apocrine gland anal sac adenocarcinoma tumors

      Explore Wiley Online Library Gastroenterology , Oncology
      Optical coherence tomography imaging of excised canine apocrine gland anal sac adenocarcinoma tumors
      Optical coherence tomography (OCT) is an optical imaging modality that has been investigated for real‐time surgical margin evaluation in human breast cancer patients. Previous veterinary OCT studies have been limited to surgical margin imaging for soft tissue sarcoma (STS) tumors. To the authors knowledge, OCT has never been used to characterize or evaluate other types of neoplasia in dogs. The goal of this study was to characterize the OCT ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign

    9. Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumors

      Explore Wiley Online Library Oncology
      Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumors
      Optical coherence tomography (OCT) uses near‐infrared light waves to generate real‐time, high‐resolution images on the microscopic scale similar to low power histopathology. Previous studies have demonstrated the use of OCT for real‐time surgical margin assessment for human breast cancer. The use of OCT for canine mammary tumors (CMT) could allow intra‐operative visualization of residual tumor at surgical margins. The purpose of this study was to ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Marina Marjanovic

    10. UIUC Receives NIH Grant for A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      UIUC Receives NIH Grant for A Snapshot Adaptive Optics and Hyperspectral Autofluorescence Fundus Camera for Age-Related Macular Degeneration (AMD)
      ...me testing of prospective therapeutic agents, saving sight and thereby providing enormous benefit to society. University of Illinois at Urbana-Champaign Receives a 2020 NIH Grant for $445,996 for A Snapshot Adaptive Opti...
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      Mentions: National Institutes of Health University of Illinois at Urbana-Champaign

    11. Otitis Media Middle Ear Effusion Identification and Characterization Using an Optical Coherence Tomography Otoscope

      Explore SAGE Journals Otolaryngology
      Otitis Media Middle Ear Effusion Identification and Characterization Using an Optical Coherence Tomography Otoscope
      Objective To determine the feasibility of detecting and differentiating middle ear effusions (MEEs) using an optical coherence tomography (OCT) otoscope. Study Design Cross-sectional study. Setting US tertiary care childrens hospital. Subjects and Methods Seventy pediatric patients undergoing tympanostomy tube placement were preoperatively imaged using an OCT otoscope. A blinded reader quiz was conducted using 24 readers from 4 groups of tiered medical expertise. The primary outcome assessed was reader ability ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton

    12. Clinical Implications of Suspended Scattering Particles in Motion Observed by Optical Coherence Tomography Angiography

      Explore Nature Publishing Group Ophthalmology
      Clinical Implications of Suspended Scattering Particles in Motion Observed by Optical Coherence Tomography Angiography
      The objective of this study was to investigate the relationship between suspended scattering particles in motion (SSPiM) in optical coherence tomography angiography (OCTA) and treatment response in diabetic macular edema (DME). We retrospectively reviewed the medical records of patients diagnosed with DME who had undergone intravitreal injection. The optical density ratio (ODR) of the intraretinal cyst and the numbers of hyperreflective foci from OCT images and SSPiM from OCTA images ...
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      Mentions: University of Illinois at Urbana-Champaign Korea University

    13. University of Illinois at Urbana Champaign Receives NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins

      Explore Optical Coherence Tomography News Funding
      University of Illinois at Urbana Champaign Receives NIH Grant for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins
      University of Illinois at Urbana Champaign Receives a 2019 NIH Grant for $405,348 for Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor Margins. The principal investigator is Stephen Boppart. Below is a summary of the proposed work. Breast cancer is a global healthcare burden, not only for the patients diagnosed with this disease, but also their families and friends. The surgical treatment of breast cancer, while successful, has significant limitations ...
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      Mentions: National Institutes of Health Stephen A. Boppart University of Illinois at Urbana-Champaign

    14. Assessing the Effect of Middle Ear Effusions on Wideband Acoustic Immittance Using Optical Coherence Tomography

      Explore LWW Online Otolaryngology
      Assessing the Effect of Middle Ear Effusions on Wideband Acoustic Immittance Using Optical Coherence Tomography
      Objectives: Wideband acoustic immittance (WAI) noninvasively assesses middle ear function by measuring the sound conduction over a range of audible frequencies. Although several studies have shown the potential of WAI for detecting the presence of middle ear effusions (MEEs), determining the effects of MEE type and amount on WAI in vivo has been challenging due to the anatomical location of middle ear cavity. The purpose of this study is to ...
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Eric J. Chaney

    15. Method and apparatus for obtaining a three-dimensional map of tympanic membrane thickness

      Explore uspto.gov Otolaryngology , Patents
      Method and apparatus for obtaining a three-dimensional map of tympanic membrane thickness
      Methods and apparatus for combining a low coherence interferometry (LCI) technique for single-point thickness measurement with videootoscopy for recording the image of a tissue such as the tympanic membrane (TM). TM thickness distribution maps are obtained by mapping the LCI imaging sites onto an anatomically accurate wide-field image of the TM, generated by mosaicking a sequence of multiple small field-of-view video-otoscopy images.
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      Mentions: Stephen A. Boppart University of Illinois at Urbana-Champaign Ryan L. Shelton
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  4. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.

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