1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 165 Articles

    2. Noise characterization of broadband fiber Cherenkov radiation as a visible-wavelength source for optical coherence tomography and two-photon fluorescence microscopy

      Noise characterization of broadband fiber Cherenkov radiation as a visible-wavelength source for optical coherence tomography and two-photon fluorescence microscopy
      ...chnology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA ^2Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA ^*Corresponding author: htu@illinois.edu ...
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    3. Feature Of The Week 10/12/14: University of Illinois at Urbana-Champaign Investigates PS-OCT with Ultimate Aim of Intraoperative Breast Cancer Tumor Margin Assessment

      Feature Of The Week 10/12/14: University of Illinois at Urbana-Champaign Investigates PS-OCT with Ultimate Aim of Intraoperative Breast Cancer Tumor Margin Assessment
      ...ntraoperative tumor margin evaluation. For more information see recent Article . Courtesy Fredrick South from University of Illinois at Urbana-Champaign . Successful treatment of breast cancer typically requires surgical...
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    4. Differentiation of ex vivo human breast tissue using polarization-sensitive optical coherence tomography

      Differentiation of ex vivo human breast tissue using polarization-sensitive optical coherence tomography

      Successful treatment of breast cancer typically requires surgical removal of the tumor. Optical coherence tomography (OCT) has been previously developed for real-time imaging of the surgical margin. However, it can be difficult to distinguish between normal stromal tissue and cancer tissue based on scattering intensity and structure alone. Polarization-sensitive optical coherence tomography (PS-OCT) is sensitive to form birefringence of biological tissue. We report on the development of a high-speed PS-OCT system and imaging of ex vivo human breast tissue, showing enhanced contrast between healthy and cancerous tissues based upon collagen content confirmed with corresponding histology. These results demonstrate the feasibility ...

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    5. UIUC Receives NIH Grant for Partnership for Primary Care Imaging

      UIUC Receives NIH Grant for Partnership for Primary Care Imaging

      University of Illinois at Urbana Champaign Received a 2014 NIH Grant for $933,337 for Partnership for Primary Care Imaging. The principal investigator is Stephen Boppart. The program began in 2011 and ends in 2016. Below is a summary of the proposed work. Primary Care Medicine, including Family Practice and Pediatrics, has traditionally relied on physical exam skills and simplistic instruments for critical diagnostic decision making, monitoring, and referral to medical specialists. The otoscope and ophthalmoscope are two historical and ubiquitous instruments that largely only illuminate and magnify tissue surfaces in the ear and eye, respectively. This Partnership will develop ...

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    6. Comparison of a MEMS-Based Handheld OCT Scanner With a Commercial Desktop OCT System for Retinal Evaluation

      Comparison of a MEMS-Based Handheld OCT Scanner With a Commercial Desktop OCT System for Retinal Evaluation

      Purpose: The goal of this study was to evaluate the ability of our handheld optical coherence tomography (OCT) scanner to image the posterior and anterior structures of the human eye, and especially the individual layers of the retina, and to compare its diagnostic performance with that of a fixed desktop commercial ophthalmic OCT system. Methods: We compared the clinical imaging results of our handheld OCT with a leading commercial desktop ophthalmic system (RTVue) used in specialist offices. Six patients exhibiting diabetes-related retinal pathology had both eyes imaged with each OCT system. Results: In both sets of images, the structural irregularities ...

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    7. University of Illinois Urbana-Champaign receives NIH Grant for Interoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins

      University of Illinois Urbana-Champaign receives NIH Grant for Interoperative Label-Free Optical Molecular Imaging of Breast Tumor Margins

      University of Illinois Urbana-Champaign received at 2014 NIH grant for $483,605 for Interoperative Label-Free Optidcal Molecular Imaging of Breast Tumor Margins. The principal investigator is Stephen Boppart. The program began in 2012 and ends in 2017. Below is a summary of the proposed work. Margin status during the surgical treatment of solid tumors is the most critical factor in determining local recurrence rates. For breast cancer, breast conserving surgeries or lumpectomies are routinely performed. Currently, the surgeon is unable to visualize the microscopic structure at the margin, and conventionally relies on post-operative histological assessment of surgical margins to verify ...

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    8. Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging

      Computational adaptive optics for interferometric synthetic aperture microscopy and other interferometric imaging

      Methods for correcting for aberrations in the image or three-dimensional reconstruction of a sampled region obtained by broadband interferometry. The sampled region is illuminated with a broadband beam of light, and light returned from the sample is detected, along with a reference beam, in order to derive an interference signal for pixels of a volume spanned by wavenumber and axes transverse to the beam propagation direction. An optimization procedure is performed with respect to a specified criterion so as to obtain an aberration-corrected image of at least one plane of the sampled region, either in a plane-specific manner or in ...

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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.