1. University of Illinois at Urbana-Champaign

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    1. Mentioned In 269 Articles

    2. Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma

      Diagnostic accuracy of optical coherence tomography for surgical margin assessment of feline injection-site sarcoma
      The invasive, locally aggressive nature of feline injection-site sarcomas (FISS) pose a unique challenge for surgeons to obtain complete margins with surgical excision. Optical coherence tomography (OCT), an imaging technology that uses light waves to generate real-time views of tissue architecture, provides an emerging solution to this dilemma by allowing fast, high-resolution scanning of surgical margins. The purpose of this study was to use OCT to assess surgical margins of ...
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    3. Handheld device for identification of microbiological constituents in the middle ear

      Handheld device for identification of microbiological constituents in the middle ear
      Methods and apparatus for identifying microbiological constituents in the middle ear. A spectrometer receives Raman-scattered light from the region of the tympanic membrane and resolves spectral features of the Raman-scattered light. A processor receives the interferometry signal and the Raman signal, and generates a Raman spectrum of the tympanic membrane and material adjacent thereto. In some embodiments of the invention, low-coherence light and substantially monochromatic excitation light are directed onto ...
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    4. Synthetic polarization-sensitive optical coherence tomography by deep learning

      Synthetic polarization-sensitive optical coherence tomography by deep learning
      Polarization-sensitive optical coherence tomography (PS-OCT) is a high-resolution label-free optical biomedical imaging modality that is sensitive to the microstructural architecture in tissue that gives rise to form birefringence, such as collagen or muscle fibers. To enable polarization sensitivity in an OCT system, however, requires additional hardware and complexity. We developed a deep-learning method to synthesize PS-OCT images by training a generative adversarial network (GAN) on OCT intensity and PS-OCT images ...
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    5. Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign

      Postdoctoral Research Associate GlaxoSmithKline Center for Optical Molecular Imaging Beckman Institute for Advanced Science and Technology University of Illinois at Urbana-Champaign
      The GlaxoSmithKline Center for Optical Molecular Imaging at the Beckman Institute for Advanced Science and Technology seeks a bright, energetic, and motivated candidate to fill a vacancy for a full-time Postdoctoral Research Associate in the area of image data analysis. The purpose of this position is to lead the analysis of image data from translational optical biomedical imaging systems. The successful candidate will need a solid and broad understanding of ...
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    6. UIUC Receives NIH Grant for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media

      UIUC Receives NIH Grant for Integration of Raman Spectroscopy and Optical Coherence Tomography (RS-OCT) for In-Vivo Identification of Bacterial Otitis Media
      ...f antibiotics, and ultimately, to efficiently improve the health of patients.

      University of Illinois at Urbana-Champaign Receives a 2021 NIH Grant for $653,667 for Integration of Raman Spe...

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    7. Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography

      Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography
      We report an automated differentiation model for classifying malignant tumor, fibro-adipose, and stroma in human breast tissues based on polarization-sensitive optical coherence tomography (PS-OCT). A total of 720 PS-OCT images from 72 sites of 41 patients with HE histology-confirmed diagnoses as the gold standard were employed in this study. The differentiation model is trained by the features extracted from both one standard OCT-based metric (i.e., intensity) and four PS-OCT-based ...
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    8. Biomechanical sensing of in vivo magnetic nanoparticle hyperthermia-treated melanoma using magnetomotive optical coherence elastography

      Biomechanical sensing of in vivo magnetic nanoparticle hyperthermia-treated melanoma using magnetomotive optical coherence elastography
      Rationale: Magnetic nanoparticle hyperthermia (MH) therapy is capable of thermally damaging tumor cells, yet a biomechanically-sensitive monitoring method for the applied thermal dosage has not been established. Biomechanical changes to tissue are known indicators for tumor diagnosis due to its association with the structural organization and composition of tissues at the cellular and molecular level. Here, by exploiting the theranostic functionality of magnetic nanoparticles (MNPs), we aim to explore the ...
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    9. Computational adaptive optics for polarization-sensitive optical coherence tomography

      Computational adaptive optics for polarization-sensitive optical coherence tomography
      Defocus aberration in optical systems, including optical coherence tomography (OCT) systems employing Gaussian illumination, gives rise to the well-known compromise between transverse resolution and depth-of-field. This results in blurry images when out-of-focus, whilst other low-order aberrations (e.g., astigmatism, coma, etc.) present in both the OCT system and biological samples further reduce image resolution and contrast. Computational adaptive optics (CAO) is a computed optical interferometric imaging technique that modifies the ...
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    10. Longitudinal optical coherence tomography to visualize the in vivo response of middle ear biofilms to antibiotic therapy

      Longitudinal optical coherence tomography to visualize the in vivo response of middle ear biofilms to antibiotic therapy
      Studying the impact of antibiotic treatment on otitis media (OM), the leading cause of primary care office visits during childhood, is critical to develop appropriate treatment strategies. Tracking dynamic middle ear conditions during antibiotic treatment is not readily applicable in patients, due to the limited diagnostic techniques available to detect the smaller amount and variation of middle ear effusion (MEE) and middle ear bacterial biofilm, responsible for chronic and recurrent ...
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    11. Simultaneous 4-phase-shifted full-field optical coherence microscopy

      Simultaneous 4-phase-shifted full-field optical coherence microscopy
      A new method is presented for full-field optical coherence tomography imaging, which permits capturing single shot phase sensitive imaging through simultaneous acquisition of four phase-shifted images with a single camera using unpolarized light for object illumination. Our method retains the full dynamic range of the camera by using different areas of a single camera sensor to capture each image. We demonstrate the performance of our method by imaging phantoms and ...
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    12. In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography

      In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography
      Decreased mobility of the human eardrum, the tympanic membrane (TM), is an essential indicator of a prevalent middle ear infection. The current diagnostic method to assess TM mobility is via pneumatic otoscopy, which provides subjective and qualitative information of subtle motion. In this study, a handheld spectral-domain pneumatic optical coherence tomography system was developed to simultaneously measure the displacement of the TM, air pressure inputs applied to a sealed ear ...
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    13. 1-15 of 269 1 2 3 4 ... 16 17 18 »
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  2. About University of Illinois at Urbana-Champaign

    University of Illinois at Urbana-Champaign

    The University of Illinois at Urbana-Champaign.  Illinois is a world leader in research, teaching, and public engagement, distinguished by the breadth of its programs, broad academic excellence, and internationally renowned faculty.  Biophotonics Imaging Laboratory at the University of Illinois at Urbana-Champaign. Located in the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign, the Biophotonics Imaging Laboratory, directed by Professor Stephen Boppart, is dedicated to the development of optical biomedical imaging techniques. Mills Breast Cancer Institute is dedicated to the diagnosis, prevention and treatment of breast cancer through collaborative research and excellence in patient care.   Dr. Stephen Boppart, MD, PhD, Founding Director, Mills Breast Cancer Institute.