1. University of Houston

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    1. Mentioned In 221 Articles

    2. Quantifying the effect of milli-molar glucose concentration on thickness of rabbit cornea with optical coherence tomography

      The cornea contributes about 65% of the eye's ability to refract light. Thus, any fluctuation in corneal thickness can cause noticeable changes in vision. The presence of glucose molecules induces a driving force for water to leave the collagen fibrils in the cornea due to the concentration gradient created, thus changing its thickness. In this study, the effect of various milli-molar glucose concentrations on corneal thickness was explored using ...
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    3. Enhanced OCT imaging of embryonic tissue with optical clearing

      Enhanced OCT imaging of embryonic tissue with optical clearing
      Optical coherence tomography (OCT) holds great promise as a routine research tool for 3-D analysis of mammalian embryos. However, despite the depth penetration afforded by this imaging modality, light attenuation in tissues imposes limitations. Here we studied the optical clearing effect of differen ... [Proc. SPIE 7168, 71682C (2009)] published Fri Feb 20, 2009.
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    4. Imaging of cardiovascular dynamics in early mouse embryos with swept source optical coherence tomography

      Imaging of cardiovascular dynamics in early mouse embryos with swept source optical coherence tomography
      Congenital cardiovascular defects are very common, occurring in 1% of live births, and cardiovascular failures are the leading cause of birth defect-related deaths in infants. To improve diagnostics, prevention and treatment of cardiovascular abnormalities, we need to understand not only how cells f ... [Proc. SPIE 7168, 71680E (2009)] published Thu Feb 19, 2009.
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    5. Optical coherence tomography in estimating molecular diffusion of drugs and analytes in ocular tissues

      Aside from other ocular drug delivery methods, topical application and follow up drug diffusion through the cornea and sclera of the eye remain the favored method, as they impose the least pain and discomfort to the patient. However, this delivery route suffers from the low permeability of epithelia ... [Proc. SPIE 7163, 71631H (2009)] published Wed Feb 18, 2009.
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    6. Live imaging of blood flow in mammalian embryos using Doppler swept-source optical coherence tomography

      Live imaging of blood flow in mammalian embryos using Doppler swept-source optical coherence tomography
      Studying hemodynamic changes during early mammalian embryonic development is critical for further advances in prevention, diagnostics, and treatment of congenital cardiovascular (CV) birth defects and diseases. Doppler optical coherence tomography (OCT) has been shown to provide sensitive measurements of blood flow in avian and amphibian embryos. We combined Doppler swept-source optical coherence tomography (DSS-OCT) and live mouse embryo culture to analyze blood flow dynamics in early embryos. SS-OCT structural imaging ...
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    7. Concentration effect on the diffusion of glucose in ocular tissues

      In this study, optical coherence tomography (OCT) was utilized in the functional imaging of glucose diffusion through scleral tissues. Permeability coefficients for different concentrations of glucose were quantified nondestructively. Obtained results indicate an inverse proportionality between the permeability coefficient and the concentration of the analyte in epithelial tissues: in-depth diffusion of solutions with lower glucose concentration was faster than those with a higher concentration. The permeability coefficient decreased from (1 ...
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    8. Functional imaging and assessment of the glucose diffusion rate in epithelial tissues in optical coherence tomography

      Functional imaging, monitoring and quantitative description of glucose diffusion in epithelial and underlying stromal tissues in vivo and controlling of the optical properties of tissues are extremely important for many biomedical applications including the development of noninvasive or minimally invasive glucose sensors as well as for therapy and diagnostics of various diseases, such as cancer, diabetic retinopathy, and glaucoma. Recent progress in the development of a noninvasive molecular diffusion biosensor ...
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    9. Ultra-sensitive monitoring of analyte concentrations using phase sensitive spectral domain OCT

      V. G. R. Manne, R. K. Manapuram, N. Sudheendran et al. The refractive index is a basic optical property of a medium which is of great importance in physics, chemistry and most of biomedical applications. In our current study we monitor the change in refractive index for aqueous solutions of glucose, CaCl, MgCl, NaCl, KCl and urea using a phase sensitive ... [Proc. SPIE 6791, 67910A (2008)] published Mon Jun 9 ...
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    10. The effect of solution concentration on diffusion in scleral tissues

      Mohamad G. Ghosn, Esteban F. Carbajal, Natasha A. Befrui et al. The calculation of permeability coefficient of analytes could potentially be used in a variety of basic science and clinical fields, as well as advanced diagnostic imaging. Before this can occur, a more thorough understanding of the diffusion rate of analytes in biological tissues is needed. For thi ... [Proc. SPIE 6791, 679107 (2008)] published Mon Jun 9, 2008.
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    11. Three-dimensional imaging of artificial fingerprint by optical coherence tomography

      Kirill V. Larin and Yezeng Cheng Fingerprint recognition is one of the popular used methods of biometrics. However, due to the surface topography limitation, fingerprint recognition scanners are easily been spoofed, e.g. using artificial fingerprint dummies. Thus, biometric fingerprint identification devices need to be more accurat ... [Proc. SPIE Int. Soc. Opt. Eng. 6944, 69440M (2008)] published Mon Mar 17, 2008.
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    12. Quantifying permeability of glucose in normal and atherosclerotic pig aorta in vitro using optical coherence tomography

      Mohamad G. Ghosn, Esteban Carbajal, Natasha Befrui et al. High in-depth resolution imaging, such as Optical Coherence Tomography, could be the next frontier in noninvasive quantification of diffusion in epithelial tissues. In this study we employed OCT in a method that could help differentiate various forms of atherosclerosis and distinguish between normal ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 68471E (2008)] published Mon Feb 18, 2008.
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    13. 196-210 of 221 « 1 2 ... 11 12 13 14 15 »
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  2. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).