1. University of Houston

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    1. Mentioned In 208 Articles

    2. Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents

      Assessment of Vascular Patency and Inflammation with Intravascular Optical Coherence Tomography in Patients with Superficial Femoral Artery Disease Treated with Zilver PTX Stents
      Purpose Zilver PTX nitinol self-expanding drug-eluting stent with paclitaxel coating is effective for treatment of superficial femoral artery (SFA) disease. However, as with any stent, it induces a measure of vascular inflammatory response. The current clinical trial (NCT02734836) aimed to assess vascular patency, remodeling, and inflammatory markers with intravascular optical coherence tomography (OCT) in patients with SFA disease treated with Zilver PTX stents. Methods Serial OCT examinations were performed in ...
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    3. University of Washington Receives NIH Grant for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality

      University of Washington Receives NIH Grant for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality
      University of Washington Receives a 2019 NIH Grant for $663,429 for Biomechanics of Neural Tube Development Using Brillouin-OCT Multimodality. The principal investigator is Kirill Larin. The program began in 2018 and ends in 2023. Below is a summary of the proposed work. The objective of this proposal is to develop a non-contact, all-optical imaging technology to map elastic moduli and forces involved in critical aspects of embryonic development with ...
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    4. Dynamic optical coherence elastography: Emerging tool for noninvasive quantification of mechanical properties of ocular tissues

      Dynamic optical coherence elastography: Emerging tool for noninvasive quantification of mechanical properties of ocular tissues
      Optical coherence elastography (OCE) is an emerging method for noninvasive quantification of tissue viscoelastic properties. The underlying technology is based on Optical Coherence Tomography (OCT) imaging and analysis of external (or internal) force-induced mechanical waves propagating through the tissue. In this presentation, I will overview recent progress made in my lab on quantification of mechanical properties of ocular tissues (such as cornea and the lens of the eye) using OCE ...
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    5. University Houston ReceivesNIH Grant for Optical Coherence Elastography of the Cornea

      University Houston ReceivesNIH Grant for Optical Coherence Elastography of the Cornea
      University Houston Receives a 2019 NIH Grant for $379,941 for Optical Coherence Elastography of the Cornea. The principal investigator is Kirill Larin. The program began in 2012 and ends in 2020. Below is a summary of the proposed work. The fundamental physical properties of the outer tunic of the eye determine the structural characteristics of the ocular globe and may be altered in several devastating disease states including axial ...
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    6. University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging

      University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging
      ... mother and developing fetus, a critical prerequisite for embryonic survival.

      University of Houston Receives a 2019 NIH Grant for $676,224 for Structural and Molecular Phenotyping of Embry...

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    7. Assessing the Acute Effects of Prenatal Synthetic Cannabinoid Exposure on Murine Fetal Brain Vasculature Using Optical Coherence Tomography

      Assessing the Acute Effects of Prenatal Synthetic Cannabinoid Exposure on Murine Fetal Brain Vasculature Using Optical Coherence Tomography
      Marijuana is one of the most commonly abused substances during pregnancy. Synthetic cannabinoids (SCBs) are a group of heterogeneous compounds that are 40‐ to 600‐fold more potent than ∆ 9 ‐tetrahydrocannabinol , the major psychoactive component of marijuana. With SCBs being legally available for purchase and the prevalence of unplanned pregnancies, the possibility of prenatal exposure to SCBs is high. However, the effects of prenatal SCB exposure on embryonic brain development ...
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    8. Optical coherence elastography of cold cataract in porcine lens

      Optical coherence elastography of cold cataract in porcine lens
      Cataract is one of the most prevalent causes of blindness around the world. Understanding the mechanisms of cataract development and progression is important for clinical diagnosis and treatment. Cold cataract has proven to be a robust model for cataract formation that can be easily controlled in the laboratory. There is evidence that the biomechanical properties of the lens can be significantly changed by cataract. Therefore, early detection of cataract, as ...
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    9. An Evaluation of the IOLMaster 700

      An Evaluation of the IOLMaster 700
      Objectives: To evaluate the repeatability and reproducibility of the Carl Zeiss Meditec IOLMaster 700, which uses swept-source optical coherence tomography technology, along with its agreement with the IOLMaster 500 and Lenstar LS 900. Methods: In a clinical practice, complete measurements were taken on one eye of 100 subjects: 51 with cataracts and 49 with clear lenses. Three sets of measurements were taken by 3 operators with three different IOLMaster 700 ...
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    10. University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effects of Poly-Drug Exposure of Fetal Brain Development

      University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effects of Poly-Drug Exposure of Fetal Brain Development
      ...particular significant impact for the development of novel and innovative therapies for reversing teratology. University of Houston Receives 2019 NIH Grant for $345,824 for Optical Coherence Tomography to Study Effects o...
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    11. Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography

      Assessing the biomechanical properties of the porcine crystalline lens as a function of intraocular pressure with optical coherence elastography
      In this study, we investigated the relationship between the biomechanical properties of the crystalline lens and intraocular pressure (IOP) using a confocal acoustic radiation force (ARF) and phase-sensitive optical coherence elastography (OCE) system. ARF induced a small displacement at the apex of porcine lenses in situ at various artificially controlled IOPs. Maximum displacement, relaxation rate, and Youngs modulus were utilized to assess the stiffness of the crystalline lens. The results ...
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    12. Understanding congenital heart defects to prevent them

      Understanding congenital heart defects to prevent them
      To understand cardiovascular failures, the leading cause of birth defect-related deaths in infants, UH professor of biomedical engineering Kirill Larin is teaming up with Baylor College of Medicine professor of cellular and molecular physiology Irina Larina on a chicken and egg hunt. "When the heart develops, it becomes stiffer as required for ability to contract and pump blood," said Larin. "So the question is - does it become stiff because it ...
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    13. Integrated optical coherence tomography and multielement ultrasound transducer probe for shear wave elasticity imaging of moving tissues

      Integrated optical coherence tomography and multielement ultrasound transducer probe for shear wave elasticity imaging of moving tissues
      Accurate measurements of microelastic properties of soft tissues in-vivo using optical coherence elastography can be affected by motion artifacts caused by cardiac and respiratory cycles. This problem can be overcome using a multielement ultrasound transducer probe where each ultrasound transducer is capable of generating acoustic radiation force (ARF) and, therefore, creating shear waves in tissue. These shear waves, produced during the phase of cardiac and respiratory cycles when tissues are ...
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    14. Modified wavelength scanning interferometry for simultaneous tomography and topography of the cornea with Fourier domain optical coherence tomography

      Modified wavelength scanning interferometry for simultaneous tomography and topography of the cornea with Fourier domain optical coherence tomography
      Visual acuity is dependent on corneal shape and size. A minor variation in surface geometry can cause a deformation of corneal geometry, which affects its optical performance. In this work we demonstrate an algorithm for the simultaneous measurement of corneal tomography and topography with a traditional point-scanning Fourier domain optical coherence tomography (FD-OCT) system. A modified wavelength scanning interferometry (mWSI) algorithm enabled topographical evaluation of the surface with nanometer-scale resolution ...
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    15. 1-15 of 208 1 2 3 4 ... 12 13 14 »
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  2. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).