1. University of Houston

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    1. Mentioned In 181 Articles

    2. Comparison and combination of rotational imaging optical coherence tomography and selective plane illumination microscopy for embryonic study

      Explore OSA | OSA Publishing Developmental Biology
      Comparison and combination of rotational imaging optical coherence tomography and selective plane illumination microscopy for embryonic study
      Several optical imaging techniques have been applied for high-resolution embryonic imaging using different contrast mechanisms, each with their own benefits and limitations. In this study, we imaged the same E9.5 mouse embryo with rotational imaging optical coherence tomography (RI-OCT) and selective plane illumination microscopy (SPIM). RI-OCT overcomes optical penetration limits of traditional OCT imaging that prohibit full-body imaging of mouse embryos at later stages by imaging the samples from ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    3. Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography

      Explore SPIE Digital Library Developmental Biology
      Evaluating biomechanical properties of murine embryos using Brillouin microscopy and optical coherence tomography
      Embryogenesis is regulated by numerous changes in mechanical properties of the cellular microenvironment. Thus, studying embryonic mechanophysiology can provide a more thorough perspective of embryonic development, potentially improving early detection of congenital abnormalities as well as evaluating and developing therapeutic interventions. A number of methods and techniques have been used to study cellular biomechanical properties during embryogenesis. While some of these techniques are invasive or involve the use of external ...
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      Mentions: University of Maryland Kirill V. Larin University of Houston

    4. Postnatal maturation of the fovea in Macaca mulatta using optical coherence tomography

      Explore ScienceDirect Ophthalmology
      Postnatal maturation of the fovea in Macaca mulatta using optical coherence tomography
      Changes in the foveal anatomy during infancy are an important component in early development of spatial vision. The present longitudinal study in rhesus monkeys was undertaken to characterize the postnatal maturation of the fovea. Starting at four weeks after birth, the retinas of the left eyes of sixteen infant monkeys were imaged using spectral domain optical coherence tomography (SD OCT). Retinal scans were repeated every 30 days during the first ...
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      Mentions: University of Houston

    5. Optical coherence elastography to assess biomechanics and detect progression of ocular and other tissues degenerative diseases

      Explore uspto.gov Ophthalmology , Patents
      Optical coherence elastography to assess biomechanics and detect progression of ocular and other tissues degenerative diseases
      An excitation force (internal or external) and phase-sensitive optical coherence elastography (OCE) system, used in conjunction with a data analyzing algorithm, is capable of measuring and quantifying biomechanical parameters of tissues in situ and in vivo. The method was approbated and demonstrated on an example of the system that combines a pulsed ultrasound system capable of producing an acoustic radiation force on the crystalline lens surface and a phase-sensitive optical ...
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      Mentions: Kirill V. Larin University of Houston Salavat Aglyamov

    6. Persistent Asymmetric Optic Disc Swelling After Long-Duration Space Flight: Implications for Pathogenesis

      Explore LWW Online Neurology , Ophthalmology
      Persistent Asymmetric Optic Disc Swelling After Long-Duration Space Flight: Implications for Pathogenesis
      Background: Several ophthalmic findings including optic disc swelling, globe flattening and choroidal folds have been observed in astronauts following long-duration space flight. The authors now report asymmetric choroidal expansion, disc swelling and optic disc morphologic changes in a 45-year-old astronaut which occurred during long-duration space flight and persisted following his space mission. Methods: Case study of ocular findings in an astronaut documented during and after a long-duration space flight of ...
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      Mentions: Johns Hopkins University University of Houston University of Colorado

    8. Applanation optical coherence elastography: noncontact measurement of intraocular pressure, corneal biomechanical properties, and corneal geometry with a single instrument

      Explore SPIE | Journal Ophthalmology
      Applanation optical coherence elastography: noncontact measurement of intraocular pressure, corneal biomechanical properties, and corneal geometry with a single instrument
      Current clinical tools provide critical information about ocular health such as intraocular pressure (IOP). However, they lack the ability to quantify tissue material properties, which are potent markers for ocular tissue health and integrity. We describe a single instrument to measure the eye-globe IOP, quantify corneal biomechanical properties, and measure corneal geometry with a technique termed applanation optical coherence elastography (Appl-OCE). An ultrafast OCT system enabled visualization of corneal dynamics ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    9. Evaluation of dermal fillers with noncontact optical coherence elastography

      Explore Conference Proceedings Dentistry
      Evaluation of dermal fillers with noncontact optical coherence elastography
      Over 2 million dermal filler procedures are performed each year in the USA alone, and this figure is only expected to increase as the aging population continues to grow. Dermal filler treatments can last from a few months to years depending on the type of filler and its placement. Although adverse reactions are rare, they can be quite severe due to ischemic events and filler migration. Previously, techniques such as ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    10. A dual-modality optical coherence tomography and selective plane illumination microscopy system for mouse embryonic imaging

      Explore Conference Proceedings Developmental Biology
      A dual-modality optical coherence tomography and selective plane illumination microscopy system for mouse embryonic imaging
      Both optical coherence tomography (OCT) and selective plane illumination microscopy (SPIM) are frequently used in mouse embryonic research for high-resolution three-dimensional imaging. However, each of these imaging methods provide a unique and independent advantage: SPIM provides morpho-functional information through immunofluorescence and OCT provides a method for whole-embryo 3D imaging. In this study, we have combined rotational imaging OCT and SPIM into a single, dual-modality device to image E9.5 mouse ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    11. Live dynamic analysis of the developing cardiovascular system in mice

      Explore Conference Proceedings Cardiology , Developmental Biology
      Live dynamic analysis of the developing cardiovascular system in mice
      The study of the developing cardiovascular system in mice is important for understanding human cardiogenesis and congenital heart defects. Our research focuses on imaging early development in the mouse embryo to specifically understand cardiovascular development under the regulation of dynamic factors like contractile force and blood flow using optical coherence tomography (OCT). We have previously developed an OCT based approach that combines static embryo culture and advanced image processing with ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    12. Optical coherence tomography for image-guided dermal filler injection and biomechanical evaluation

      Explore Conference Proceedings Dermatology
      Optical coherence tomography for image-guided dermal filler injection and biomechanical evaluation
      Dermal fillers are a very popular anti-aging treatment with estimated sales in the billions of dollars and millions of procedures performed. As the aging population continues to grow, these figures are only expected to increase. Dermal fillers have various compositions depending on their intended application. Reactions to dermal fillers can be severe, such as ischemic events and filler migration to the eyes. However, these adverse reactions are rare. Nevertheless, the ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    13. Ultra-fast line-field low coherence holographic elastography using spatial phase shifting

      Explore OSA | OSA Publishing
      Ultra-fast line-field low coherence holographic elastography using spatial phase shifting
      Optical coherence elastography (OCE) is an emerging technique for quantifying tissue biomechanical properties. Generally, OCE relies on point-by-point scanning. However, long acquisition times make point-by-point scanning unfeasible for clinical use. Here we demonstrate a noncontact single shot line-field low coherence holography system utilizing an automatic Hilbert transform analysis based on a spatial phase shifting technique. Spatio-temporal maps of elastic wave propagation were acquired with only one air-pulse excitation and used ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    14. Optical coherence elastography – OCT at work in tissue biomechanics [Invited]

      Explore OSA | OSA Publishing
      Optical coherence elastography – OCT at work in tissue biomechanics [Invited]
      Optical coherence elastography (OCE), as the use of OCT to perform elastography has come to be known, began in 1998, around ten years after the rest of the field of elastography the use of imaging to deduce mechanical properties of tissues. After a slow start, the maturation of OCT technology in the early to mid 2000s has underpinned a recent acceleration in the field. With more than 20 papers published ...
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      Mentions: Kirill V. Larin University of Houston David D. Sampson

    15. The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development

      Explore Optical Coherence Tomography News Developmental Biology , Neurology , Funding
      The University of Houston Receives NIH Grant for Optical Coherence Tomography to Study Effect of Poly-Drug Exposure on Fetal Brain Development
      ...icular significant impact for the development of novel and innovative therapies for reversing teratology. The University of Houston Receives a 2017 NIH Grant for $311,241 for Optical Coherence Tomography to Study Effect ...
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      Mentions: National Institutes of Health Kirill V. Larin University of Houston

    16. Dynamic imaging and quantitative analysis of cranial neural tube closure in the mouse embryo using optical coherence tomography

      Explore OSA | OSA Publishing Developmental Biology , Neurology
      Dynamic imaging and quantitative analysis of cranial neural tube closure in the mouse embryo using optical coherence tomography
      Neural tube closure is a critical feature of central nervous system morphogenesis during embryonic development. Failure of this process leads to neural tube defects, one of the most common forms of human congenital defects. Although molecular and genetic studies in model organisms have provided insights into the genes and proteins that are required for normal neural tube development, complications associated with live imaging of neural tube closure in mammals limit ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston
    17. 1-15 of 181 1 2 3 4 ... 10 11 12 »
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  4. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).

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