1. University of Houston

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    1. Mentioned In 244 Articles

    2. Longitudinal assessment of the effect of alkali burns on corneal biomechanical properties using optical coherence elastography

      Explore Wiley Online Library Ophthalmology
      Longitudinal assessment of the effect of alkali burns on corneal biomechanical properties using optical coherence elastography
      Eye injury due to alkali burn is a severe ocular trauma that can profoundly affect corneal structure and function, including its biomechanical properties. Here, we assess the changes in the mechanical behavior of mouse corneas in response to alkali-induced injury by conducting longitudinal measurements using optical coherence elastography (OCE). A non-contact air-coupled ultrasound transducer was used to induce elastic waves in control and alkali-injured mouse corneas in vivo, which were ...
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      Mentions: University of Houston

    3. Spatial Assessment of Heterogeneous Tissue Natural Frequency Using Micro-Force Optical Coherence Elastography

      Explore Frontiers
      Spatial Assessment of Heterogeneous Tissue Natural Frequency Using Micro-Force Optical Coherence Elastography
      Analysis of corneal tissue natural frequency was recently proposed as a biomarker for corneal biomechanics and has been performed using high-resolution optical coherence tomography (OCT)-based elastography (OCE). However, it remains unknown whether natural frequency analysis can resolve local variations in tissue structure. We measured heterogeneous samples to evaluate the correspondence between natural frequency distributions and regional structural variations. Sub-micrometer sample oscillations were induced point-wise by microliter air pulses (6085 ...
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      Mentions: University of Houston

    4. Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging

      Explore Optica Publishing Group
      Multimodal imaging system combining optical coherence tomography and Brillouin microscopy for neural tube imaging
      To understand the dynamics of tissue stiffness during neural tube formation and closure in a murine model, we have developed a multimodal, coaligned imaging system combining optical coherence tomography (OCT) and Brillouin microscopy. Brillouin microscopy can map the longitudinal modulus of tissue but cannot provide structural images. Thus, it is limited for imaging dynamic processes such as neural tube formation and closure. To overcome this limitation, we have combined Brillouin ...
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      Mentions: Baylor College of Medicine University of Houston

    5. Assessing Porcine Iris Elasticity and Mechanical Anisotropy with Optical Coherence Elastography

      Explore jbpe.ssau.ru Ophthalmology
      Assessing Porcine Iris Elasticity and Mechanical Anisotropy with Optical Coherence Elastography
      The relaxation and contraction of the sphincter and dilator muscles of the iris play a critical role in vision, yet little is known about the biomechanic al properties of these mus cles. This study aimed to determine the elastic properties of the iris as a function of its anatomy and intraocular pressure. A high - resolution phase - sensitive OCE system was employed to detect acoustic radiation force induced propagation of elastic ...
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      Mentions: University of Houston

    6. Ultra-fast dynamic line-field optical coherence elastography

      Explore OSA | OSA Publishing
      Ultra-fast dynamic line-field optical coherence elastography
      Abstract In this work, we present an ultra-fast line-field optical coherence elastography system (LF-OCE) with an 11.5 MHz equivalent A-line rate. The system was composed of a line-field spectral domain optical coherence tomography system based on a supercontinuum light source, Michelson-type interferometer, and a high-speed 2D spectrometer. The system performed ultra-fast imaging of elastic waves in tissue-mimicking phantoms of various elasticities.
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      Mentions: Baylor College of Medicine University of Houston

    7. Accuracy of Common Motion Estimators in Wave-Based Optical Coherence Elastography

      Explore jbpe.ssau.ru
      Accuracy of Common Motion Estimators in Wave-Based Optical Coherence Elastography
      Abstract. Motion estimators are commonly used in shear wave optical coherence elastography to compute small displacements. This work focuses on comparing three motion estimators: Kasai, Loupas, and the vector method. Our results show that the vector method is superi or in low - SNR, low - amplitude situations for group velocity calculation and profile reconstruction . 202 1 Journal of Biomedical Photonics Engineering.
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      Mentions: University of Houston

    8. Multimodal high-resolution embryonic imaging with light sheet fluorescence microscopy and optical coherence tomography

      Explore OSA | OSA Publishing Microscopy
      Multimodal high-resolution embryonic imaging with light sheet fluorescence microscopy and optical coherence tomography
      A high-resolution imaging system combining optical coherence tomography (OCT) and light sheet fluorescence microscopy (LSFM) was developed. LSFM confined the excitation to only the focal plane, removing the out of plane fluorescence. This enabled imaging a murine embryo with higher speed and specificity than traditional fluorescence microscopy. OCT gives information about the structure of the embryo from the same plane illuminated by LSFM. The co-planar OCT and LSFM instrument was ...
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      Mentions: Baylor College of Medicine University of Houston

    10. Deep learning improves image reconstruction in optical coherence tomography using less data

      Explore PhysOrg.com Ophthalmology
      Deep learning improves image reconstruction in optical coherence tomography using less data
      Optical coherence tomography (OCT) is a non-invasive imaging method that can provide 3D information of biological samples. The first generation of OCT systems were based on time-domain imaging, using a mechanical scanning set-up. However, the relatively slow data acquisition speed of these earlier time-domain OCT systems partially limited their use for imaging live specimen. The introduction of the spectral-domain OCT techniques with higher sensitivity has contributed to a dramatic increase ...
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      Mentions: University of Houston UCLA

    13. In vivo human corneal natural frequency quantification using dynamic optical coherence elastography: repeatability and reproducibility

      Explore ScienceDirect Ophthalmology
      In vivo human corneal natural frequency quantification using dynamic optical coherence elastography: repeatability and reproducibility
      Reliable and quantitative assessment of corneal biomechanics is important for the detection and treatment of corneal disease. The present study evaluates the repeatability and reproducibility of a novel optical coherence tomography (OCT)-based elastography (OCE) method for in vivo quantification of corneal natural frequency in 20 normal human eyes. Sub-micron corneal oscillations were induced by repeated low-force (13 Pa) microliter air pulses at the corneal apex and were observed by ...
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      Mentions: University of Houston

    14. Neural network-based image reconstruction in swept-source optical coherence tomography using undersampled spectral data

      Explore Home - IEEE Photonics Society
      Neural network-based image reconstruction in swept-source optical coherence tomography using undersampled spectral data
      Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate swept-source OCT (SS-OCT) images using undersampled spectral data, without any spatial aliasing artifacts. This neural network-based image reconstruction does not require any hardware changes to the optical set- up and can be easily integrated with existing swept-source or ...
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      Mentions: Baylor College of Medicine University of Houston UCLA

    15. Heartbeat optical coherence elastography: corneal biomechanics in vivo

      Explore SPIE Digital Library Developmental Biology
      Heartbeat optical coherence elastography: corneal biomechanics in vivo
      Significance: Mechanical assessment of the cornea can provide important structural and functional information regarding its health. Current clinically available tools are limited in their efficacy at measuring corneal mechanical properties. Elastography allows for the direct estimation of mechanical properties of tissues in vivo but is generally performed using external excitation force. Aim: To show that heartbeat optical coherence elastography (Hb-OCE) can be used to assess the mechanical properties of the ...
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      Mentions: University of Houston

    16. In Vivo Human Corneal Shear-wave Optical Coherence Elastography

      Explore LWW Online Ophthalmology
      In Vivo Human Corneal Shear-wave Optical Coherence Elastography
      SIGNIFICANCE A novel imaging technology, dynamic optical coherence elastography (OCE), was adapted for clinical noninvasive measurements of corneal biomechanics. PURPOSE Determining corneal biomechanical properties is a long-standing challenge. Elasticity imaging methods have recently been developed and applied for clinical evaluation of soft tissues in cancer detection, atherosclerotic plaque evaluation, surgical guidance, and more. Here, we describe the use of dynamic OCE to characterize mechanical wave propagation in the human cornea ...
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      Mentions: University of Alabama University of Houston
    17. 1-15 of 244 1 2 3 4 ... 15 16 17 »
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  4. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).

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