1. University of Houston

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    1. Mentioned In 230 Articles

    2. In Vivo Human Corneal Shear-wave Optical Coherence Elastography

      Explore LWW Online Ophthalmology
      In Vivo Human Corneal Shear-wave Optical Coherence Elastography
      SIGNIFICANCE A novel imaging technology, dynamic optical coherence elastography (OCE), was adapted for clinical noninvasive measurements of corneal biomechanics. PURPOSE Determining corneal biomechanical properties is a long-standing challenge. Elasticity imaging methods have recently been developed and applied for clinical evaluation of soft tissues in cancer detection, atherosclerotic plaque evaluation, surgical guidance, and more. Here, we describe the use of dynamic OCE to characterize mechanical wave propagation in the human cornea ...
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      Mentions: Kirill V. Larin University of Alabama University of Houston

    3. Confocal air-coupled ultrasonic optical coherence elastography probe for quantitative biomechanics

      Explore OSA | OSA Publishing Ophthalmology
      Confocal air-coupled ultrasonic optical coherence elastography probe for quantitative biomechanics
      We present an air-coupled ultrasonic radiation force probe co-focused with a phase-sensitive optical coherence tomography (OCT) system for quantitative wave-based elastography. A custom-made 1 MHz spherically focused piezoelectric transducer with a concentric 10 mm wide circular opening allowed for confocal micro-excitation of waves and phase-sensitive OCT imaging.
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      Mentions: Kirill V. Larin University of Houston Michael D. Twa

    5. Dynamic Optical Coherence Elastography of the Anterior Eye: Understanding the Biomechanics of the Limbus

      Explore IOVS Journal Ophthalmology
      Dynamic Optical Coherence Elastography of the Anterior Eye: Understanding the Biomechanics of the Limbus
      Purpose : Currently, the biomechanical properties of the corneo-scleral limbus when the eye-globe deforms are largely unknown. The purpose of this study is to evaluate changes in elasticity of the cornea, sclera, and limbus when subjected to different intraocular pressures (IOP) using wave-based optical coherence elastography (OCE). Special attention was given to the elasticity changes of the limbal region with respect to the elasticity variations in the neighboring corneal and scleral ...
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      Mentions: Kirill V. Larin University of Houston Michael D. Twa

    7. University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality

      Explore Optical Coherence Tomography News Neurology , Funding
      University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality
      ...vents leading to NTDs and potentially other complex congenital malformations.

      University of Houston Receives a 2020 NIH Grant for $633,348 for Biomechanics of Neural Tube Development using...

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      Mentions: National Institutes of Health Kirill V. Larin University of Houston

    9. Optical coherence tomography angiography to evaluate murine fetal brain vasculature changes caused by prenatal exposure to nicotine

      Explore OSA | OSA Publishing
      Optical coherence tomography angiography to evaluate murine fetal brain vasculature changes caused by prenatal exposure to nicotine
      Maternal smoking causes several defects ranging from intrauterine growth restriction to sudden infant death syndrome and spontaneous abortion. While several studies have documented the effects of prenatal nicotine exposure in development and behavior, acute vasculature changes in the fetal brain due to prenatal nicotine exposure have not been evaluated yet. This study uses correlation mapping optical coherence angiography to evaluate changes in fetal brain vasculature flow caused by maternal exposure ...
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      Mentions: Baylor College of Medicine Kirill V. Larin University of Houston

    10. ASSESSING TERATOGEN-INDUCED CHANGES IN MURINE FETAL BRAIN VASCULATURE USING IN UTERO OPTICAL COHERENCE TOMOGRAPHY (Thesis)

      Explore Repository Home Neurology , Student Theses
      ASSESSING TERATOGEN-INDUCED CHANGES IN MURINE FETAL BRAIN VASCULATURE USING IN UTERO OPTICAL COHERENCE TOMOGRAPHY (Thesis)
      This dissertation reports the use of in utero optical coherence tomography to evaluate changes in vasculature in a developing murine fetal brain caused due to prenatal exposure to teratogens. Embryogenesis is a highly complex process that is extremely vulnerable to external factors. Proper visualization of embryonic development is crucial to understand the basic physiological processes and identify defects if any. This dissertation is divided into two major sections: 1) assessing ...
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      Mentions: University of Houston

    12. Heartbeat OCE: corneal biomechanical response to simulated heartbeat pulsation measured by optical coherence elastography

      Explore SPIE Digital Library
      Heartbeat OCE: corneal biomechanical response to simulated heartbeat pulsation measured by optical coherence elastography
      Significance: It is generally agreed that the corneal mechanical properties are strongly linked to many eye diseases and could be used to assess disease progression and response to therapies. Elastography is the most notable method of assessing corneal mechanical properties, but it generally requires some type of external excitation to induce a measurable displacement in the tissue. Aim: We present Heartbeat Optical Coherence Elastography (Hb-OCE), a truly passive method that ...
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      Mentions: Kirill V. Larin University of Houston Manmohan Singh

    15. Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration

      Explore TVST Journal Ophthalmology
      Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration
      Purpose : Normal physiological movements (e.g., respiration and heartbeat) induce eye motions during clinical measurements of human corneal biomechanical properties using optical coherence elastography (OCE). We quantified the effects of respiratory and cardiac-induced eye motions on clinical corneal OCE measurement precision and repeatability. Methods : Corneal OCE was performed using low-force, micro-air-pulse tissue stimulation and high-resolution phase-sensitive optical coherence tomography (OCT) imaging. Axial surface displacements of the corneal apex were measured ...
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      Mentions: Kirill V. Larin University of Alabama University of Houston
    17. 1-15 of 230 1 2 3 4 ... 14 15 16 »
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  4. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).

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