1. University of Houston

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    1. Mentioned In 225 Articles

    2. University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality

      University of Houston Receives a 2020 NIH Grant for Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality
      ...vents leading to NTDs and potentially other complex congenital malformations.

      University of Houston Receives a 2020 NIH Grant for $633,348 for Biomechanics of Neural Tube Development using...

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    3. Optical coherence tomography angiography to evaluate murine fetal brain vasculature changes caused by prenatal exposure to nicotine

      Optical coherence tomography angiography to evaluate murine fetal brain vasculature changes caused by prenatal exposure to nicotine
      Maternal smoking causes several defects ranging from intrauterine growth restriction to sudden infant death syndrome and spontaneous abortion. While several studies have documented the effects of prenatal nicotine exposure in development and behavior, acute vasculature changes in the fetal brain due to prenatal nicotine exposure have not been evaluated yet. This study uses correlation mapping optical coherence angiography to evaluate changes in fetal brain vasculature flow caused by maternal exposure ...
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    4. ASSESSING TERATOGEN-INDUCED CHANGES IN MURINE FETAL BRAIN VASCULATURE USING IN UTERO OPTICAL COHERENCE TOMOGRAPHY (Thesis)

      ASSESSING TERATOGEN-INDUCED CHANGES IN MURINE FETAL BRAIN VASCULATURE USING IN UTERO OPTICAL COHERENCE TOMOGRAPHY (Thesis)
      This dissertation reports the use of in utero optical coherence tomography to evaluate changes in vasculature in a developing murine fetal brain caused due to prenatal exposure to teratogens. Embryogenesis is a highly complex process that is extremely vulnerable to external factors. Proper visualization of embryonic development is crucial to understand the basic physiological processes and identify defects if any. This dissertation is divided into two major sections: 1) assessing ...
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    5. Heartbeat OCE: corneal biomechanical response to simulated heartbeat pulsation measured by optical coherence elastography

      Heartbeat OCE: corneal biomechanical response to simulated heartbeat pulsation measured by optical coherence elastography
      Significance: It is generally agreed that the corneal mechanical properties are strongly linked to many eye diseases and could be used to assess disease progression and response to therapies. Elastography is the most notable method of assessing corneal mechanical properties, but it generally requires some type of external excitation to induce a measurable displacement in the tissue. Aim: We present Heartbeat Optical Coherence Elastography (Hb-OCE), a truly passive method that ...
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    6. Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration

      Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration
      Purpose : Normal physiological movements (e.g., respiration and heartbeat) induce eye motions during clinical measurements of human corneal biomechanical properties using optical coherence elastography (OCE). We quantified the effects of respiratory and cardiac-induced eye motions on clinical corneal OCE measurement precision and repeatability. Methods : Corneal OCE was performed using low-force, micro-air-pulse tissue stimulation and high-resolution phase-sensitive optical coherence tomography (OCT) imaging. Axial surface displacements of the corneal apex were measured ...
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    7. Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy

      Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy
      Assessing the biomechanical properties of the crystalline lens can provide crucial information for diagnosing disease and guiding precision therapeutic interventions. Existing noninvasive methods have been limited to global measurements. Here, we demonstrate the quantitative assessment of the elasticity of crystalline lens with a multimodal optical elastography technique, which combines dynamic wave-based optical coherence elastography (OCE) and Brillouin microscopy to overcome the drawbacks of individual modalities. OCE can provide direct measurements ...
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    8. Laser-induced elastic wave classification: thermoelastic versus ablative regimes for all-optical elastography applications

      Laser-induced elastic wave classification: thermoelastic versus ablative regimes for all-optical elastography applications
      Significance : Shear wave optical coherence elastography is an emerging technique for characterizing tissue biomechanics that relies on the generation of elastic waves to obtain the mechanical contrast. Various techniques, such as contact, acoustic, and pneumatic methods, have been used to induce elastic waves. However, the lack of higher-frequency components within the elastic wave restricts their use in thin samples. The methods also require moving parts and/or tubing, which therefore ...
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    9. University of Houston Receives NIH Grant for Artificial Intelligence for Optical Coherence Tomography To Study Effects of Poly-Drug Exposure on Fetal Brain Development

      University of Houston Receives NIH Grant for Artificial Intelligence for Optical Coherence Tomography To Study Effects of Poly-Drug Exposure on Fetal Brain Development
      ...r the development of novel and innovative therapies for reversing teratology.

      University of Houston Receives a 2020 NIH Grant for $311,241 for Artificial Intelligence for Optical Coherence...

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  2. About University of Houston

    University of Houston

    University of Houston is a public doctoral/research university located in Houston, Texas. It is the flagship institution and the only doctoral degree-granting university in the University of Houston System, which includes three other universities and two multi-institution teaching centers.  Biomedical Optics Laboratory at the University of Houston is located within the Biomedical Engineering and Mechanical Enginnering Department at the University of Houston (UH). The research activities of the laboratory, under the direction of Dr. Kirill Larin, concern the development of new methods for protein biosensing (based on nanooptics) and tissue functional imaging (based on Optical Coherence Tomography).