1. University of Hong Kong

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    1. Mentioned In 87 Articles

    2. Detecting glaucoma based on spectral domain optical coherence tomography imaging of peripapillary retinal nerve fiber layer: a comparison study between hand-crafted features and deep learning model

      Detecting glaucoma based on spectral domain optical coherence tomography imaging of peripapillary retinal nerve fiber layer: a comparison study between hand-crafted features and deep learning model
      Purpose To develop a deep learning (DL) model for automated detection of glaucoma and to compare diagnostic capability against hand-craft features (HCFs) based on spectral domain optical coherence tomography (SD-OCT) peripapillary retinal nerve fiber layer (pRNFL) images. Methods A DL model with pre-trained convolutional neural network (CNN) based was trained using a retrospective training set of 1501 pRNFL OCT images, which included 690 images from 153 glaucoma patients and 811 ...
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    3. Macular Vessel Density Measured With Optical Coherence Tomography Angiography and Its Associations in a Large Population-Based Study

      Macular Vessel Density Measured With Optical Coherence Tomography Angiography and Its Associations in a Large Population-Based Study
      Purpose : We investigate macular perfusion and the systemic and ocular associations in a population-based setting. Methods : In this cross-sectional study, 2018 adults residing in Hong Kong underwent detailed ophthalmic examinations after consenting to participate. Macular perfusion was measured with optical coherence tomography angiography (OCTA) using the split-spectrum amplitude decorrelation angiography algorithm. The parafoveal flow index and vessel area density were quantified using automated custom-built software. Results : Of the 2018 participants ...
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    4. Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis

      Detection of glaucomatous optic neuropathy with spectral-domain optical coherence tomography: a retrospective training and validation deep-learning analysis
      ...60%), testing (20%), and primary validation (20%) from electronic medical and research records at the Chinese University of Hong Kong Eye Centre (Hong Kong, China) and the Hong Kong Eye Hospital (Hong Kong, China). Resid...
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    5. Swept-source optical coherence tomographic observation on prevalence and variations of cemento-enamel junction morphology

      Swept-source optical coherence tomographic observation on prevalence and variations of cemento-enamel junction morphology
      To investigate the prevalence of different patterns of cemento-enamel junction (CEJ) morphology under swept-source optical coherence tomography (SS-OCT). One hundred extracted human teeth were used consisting of incisors, premolars, and molars. Each sample was observed for every 500 m circumferentially along CEJ and OCT images of the pattern were noted. Microscopic observations were done for the representative sample using confocal laser scanning microscope (CLSM) and transmission electron microscope (TEM). The ...
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    6. Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment

      Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment
      Background and objective: Endometrial angiogenesis is a prerequisite for successful pregnancy. Optical coherence tomography (OCT) is a non-invasive physically optical imaging technique widely used in ophthalmology and cardiology. However, there is no study using OCT to evaluate endometrium. The aim of this study was to use OCT and traditionally histological methods to investigate endometrial vascularization in women undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment and to determine the association with ...
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    7. New Volumetric Analysis Method for Stent Expansion and its Correlation With Final Fractional Flow Reserve and Clinical Outcome An ILUMIEN I Substudy

      New Volumetric Analysis Method for Stent Expansion and its Correlation With Final Fractional Flow Reserve and Clinical Outcome An ILUMIEN I Substudy
      Download figure Open in new tab Download powerpoint Abstract Objectives This study sought to compare conventional methodology (CM) with a newly described optical coherence tomography (OCT)-derived volumetric stent expansion analysis in terms of fractional flow reserve (FFR)-derived physiology and device-oriented composite endpoints (DoCE). Background The analysis of coronary stent expansion with intracoronary imaging has used CM that relies on the analysis of selected single cross-sections for several decades ...
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    8. Establishment of healing profile and neointimal transformation in the new polymer-free Biolimus A9-coated coronary stent by longitudinal sequential optical coherence tomography assessments: The EGO-BIOFREEDOM study

      Establishment of healing profile and neointimal transformation in the new polymer-free Biolimus A9-coated coronary stent by longitudinal sequential optical coherence tomography assessments: The EGO-BIOFREEDOM study
      Aims: In patients at high bleeding risk treated with 1 month of dual antiplatelet therapy, the polymer-free, biolimus A9-coated BioFreedom stent (BFS) was found safer and more efficacious than bare metal stents. We used sequential optical coherence tomography (OCT) to assess the time course of strut coverage and neointimal transformation from 1 to 9 months. Methods and results: We randomly assigned 104 BFS recipients to 1 of 5 groups with ...
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    9. Spatio-temporally incremental fiber swept source

      Spatio-temporally incremental fiber swept source
      A spatio-temporally incremental fiber sweep source includes a laser light pulse generator for generating light pulses and a fiber array of individual optical fibers. The fiber array has an input end and an output end, with the fibers at the input end receiving the light pulses substantially simultaneously. The optical fibers at the output end are arranged in a raster scan pattern, e.g., a square pattern, wherein the optical ...
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    10. The OCT-ORION Study A Randomized Optical Coherence Tomography Study Comparing Resolute Integrity to Biomatrix Drug-Eluting Stent on the Degree of Early Stent Healing and Late Lumen Loss

      The OCT-ORION Study A Randomized Optical Coherence Tomography Study Comparing Resolute Integrity to Biomatrix Drug-Eluting Stent on the Degree of Early Stent Healing and Late Lumen Loss
      Background Durable polymers used in drug-eluting stents are considered a potential cause of hypersensitivity inflammatory response adversely affecting stent healing. Using a sequential follow-up with optical coherence tomography, we compared the differences in healing profiles of 2 drug-eluting stents with a biodegradable or durable polymer. Methods and Results Sixty patients with multivessel disease were prospectively enrolled to receive both study stents, which were randomly assigned to 2 individual vessels, a ...
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    11. The OCT-ORION Study: A Randomized Optical Coherence Tomography Study Comparing Resolute Integrity to Biomatrix Drug-Eluting Stent on the Degree of Early Stent Healing and Late Lumen Loss

      The OCT-ORION Study: A Randomized Optical Coherence Tomography Study Comparing Resolute Integrity to Biomatrix Drug-Eluting Stent on the Degree of Early Stent Healing and Late Lumen Loss
      ...and Late Lumen Loss) was a prospective, randomized, single-center study conducted at Queen Mary Hospital, the University of Hong Kong. This study was designed to enroll a real-world, all-comers population with symptomati...
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    12. Point-spread function manipulation of the swept-source optical coherence tomography through temporal phase modulation

      Point-spread function manipulation of the swept-source optical coherence tomography through temporal phase modulation
      Recent breakthroughs in microscopy have surpassed Abbes spatial diffraction limit, especially in the regime of fluorescence imaging. Microcopys depth-imaging relative tomography is, however, still confined to basic imaging quality, which is limited by the Fourier bandwidth. In this paper, we explore the analogy between spatial microscopy and temporal tomography based on the space-time duality, and hence enlighten the advancement of tomography. As a proof-of-principle demonstration, an all-optical manipulation of the ...
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    13. Differences in optical coherence tomography findings between an endothelial progenitor cell-capture sirolimuseluting stent and a paclitaxel-eluting stent: insights from the OCT substudy of the REMEDEE first-in-man trial

      Differences in optical coherence tomography findings between an endothelial progenitor cell-capture sirolimuseluting stent and a paclitaxel-eluting stent: insights from the OCT substudy of the REMEDEE first-in-man trial
      Aims: First-generation DES are associated with delayed endothelial coverage and poor stent healing, increasing the risk of late stent thrombosis, late catch-up and neoatherosclerosis. This observational REMEDEE substudy aimed to examine differences in vascular healing by OCT between the EPC-capture sirolimus-eluting COMBO stent and a paclitaxel-eluting stent (TAXUS). Methods and results: A subset of 33 patients (COMBO=23, TAXUS=10) with de novo coronary artery lesions in the REMEDEE study ...
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    14. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study

      Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
      Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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  2. About University of Hong Kong

    University of Hong Kong

    University of Hong Kong, as a leading international institution of higher learning in Asia, strives to attract and nurture outstanding scholars from around the world through excellence and innovation in teaching and learning, research and knowledge exchange, contributing to the advancement of society and the development of leaders through a global presence, regional significance and engagement with the rest of China.